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searching for MDA5 16 found (43 total)

alternate case: mDA5

Caetano Reis e Sousa (612 words) [view diff] exact match in snippet view article find links to article

Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature. 441 (7089):

Yorgo Modis (1,494 words) [view diff] exact match in snippet view article find links to article

by DNA curvature. EMBO J. 31, 919-31. Ian C. Berke & Yorgo Modis (2012). MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded

Theiler's encephalomyelitis virus (1,153 words) [view diff] exact match in snippet view article find links to article

phosphorylation, by inhibiting an unknown intermediate step after RIG-I/MDA5 activation of IKKε and TBK1 kinases. The L protein has been shown to be critical

Mga, max dimerization protein (241 words) [view diff] exact match in snippet view article find links to article

Retrieved 2018-03-23. Parsons KS, Hsu AC, Wark PA (January 2014). "TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial

DAK (gene) (538 words) [view diff] exact match in snippet view article

D, Zhai Z, Zhong B, Tien P, Shu HB (July 2007). "Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone

Shizuo Akira (743 words) [view diff] exact match in snippet view article find links to article

and later the RNA helicases, RIG-I (retinoic-acid-inducible protein I) and MDA5 (melanoma differentiation-associated protein 5). All molecules belong to

Viral strategies for immune response evasion (1,059 words) [view diff] exact match in snippet view article find links to article

viral protein processing but also cleave cytoplasmic recognition proteins MDA5 and RIG-I, further demonstrating the extent to which viruses can reduce Interferon

Interferon (7,065 words) [view diff] exact match in snippet view article find links to article

membrane bound toll like receptors or the cytoplasmic receptors RIG-I or MDA5, can trigger release of IFNs. Toll Like Receptor 3 (TLR3) is important for

Pestivirus (3,949 words) [view diff] exact match in snippet view article find links to article

2021). "Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production". Virus

ADAR (4,802 words) [view diff] exact match in snippet view article find links to article

Higuchi M, Hartner JC, et al. (September 2015). "RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself". Science. 349 (6252): 1115–1120.

Senescence-associated secretory phenotype (4,461 words) [view diff] exact match in snippet view article find links to article

Senescent cells release mt-dsRNA into the cytosol driving the SASP via RIGI/MDA5/MAVS/MFN1. Moreover, senescent cells are hypersensitive to mt-dsRNA-driven

Timeline of aging research (18,823 words) [view diff] exact match in snippet view article find links to article

senescent cells release mt-dsRNA into the cytosol driving the SASP via RIGI/MDA5/MAVS/MFN1, and in turn are hypersensitive to mt-dsRNA-driven inflammation

List of autoimmune diseases (6,053 words) [view diff] exact match in snippet view article find links to article

Fabien, Nicole; Coutant, Frédéric (2021-10-20). "Dermatomyositis With Anti-MDA5 Antibodies: Bioclinical Features, Pathogenesis and Emerging Therapies". Frontiers

2023 in anime (9,995 words) [view diff] exact match in snippet view article find links to article

(performed theme songs for The Gokusen, and Tottemo! Luckyman), dies from anti-MDA5 dermatomyositis and interstitial lung disease at age 73. Pineda, Rafael Antonio

Epitranscriptome (7,732 words) [view diff] case mismatch in snippet view article find links to article

for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5". Nature Immunology. 12 (2): 137–43. doi:10.1038/ni.1979. PMC 3182538. PMID 21217758

Stress granule (12,460 words) [view diff] exact match in snippet view article find links to article

Huntingtin Huntingtin IBTK IBTK Inhibitor Of Bruton Tyrosine Kinase IFIH1 MDA5 Interferon Induced With Helicase C Domain 1 IGF2BP1 IGF2BP1 Insulin-like