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searching for Interleukin 6 215 found (644 total)

alternate case: interleukin 6

Vobarilizumab (213 words) [view diff] no match in snippet view article find links to article

autoimmune diseases. This drug was developed by Ablynx NV to block interleukin-6 receptor. Vobarilizumab has been evaluated in patients with rheumatoid
Ciliary neurotrophic factor receptor (146 words) [view diff] no match in snippet view article find links to article
the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell
Oncostatin M receptor (1,631 words) [view diff] exact match in snippet view article find links to article
type I cytokine receptor family. This protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with
Glial scar (2,950 words) [view diff] no match in snippet view article find links to article
well as a reduction in inflammation and angiogenesis, were observed. Interleukin-6 (IL-6) is thought to be a molecular mediator of glial scar formation
Hyper-IL-6 (1,664 words) [view diff] no match in snippet view article find links to article
four-helical cytokine Interleukin-6 and the soluble Interleukin-6 receptor which are covalently linked by a flexible peptide linker. Interleukin-6 on target cells
MAPK13 (1,013 words) [view diff] no match in snippet view article find links to article
"Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid". J. Biol
PTPN11 (4,300 words) [view diff] no match in snippet view article find links to article
2003). "SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130". J. Biol. Chem. 278 (1): 661–71. doi:10.1074/jbc
SOCS3 (1,922 words) [view diff] no match in snippet view article find links to article
2003). "SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130". J. Biol. Chem. 278 (1): 661–71. doi:10.1074/jbc
Mir-301 microRNA precursor family (551 words) [view diff] no match in snippet view article find links to article
of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes". Hepatology. 51 (3): 881–90. doi:10
PIAS3 (2,265 words) [view diff] case mismatch in snippet view article find links to article
PIAS3 was found to interact specifically with phosphorylated STAT3 in Interleukin -6 (IL-6) activated murine myeloblast M1 cells. This interaction is mediated
Signal-regulatory protein alpha (1,664 words) [view diff] no match in snippet view article find links to article
production regulation of interleukin-1 beta production regulation of interleukin-6 production regulation of tumor necrosis factor production negative regulation
PTPN2 (1,206 words) [view diff] no match in snippet view article find links to article
"The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation". Biochem
STAT1 (3,747 words) [view diff] exact match in snippet view article find links to article
Epidermal Growth Factor (EGF), Platelet Derived Growth Factor (PDGF), Interleukin 6 (IL-6), or IL-27. Type I interferons (IFN-α, IFN-ß) bind to receptors
MAPKAPK2 (1,726 words) [view diff] no match in snippet view article find links to article
1996). "The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor". The EMBO Journal. 15 (8):
Mir-365 microRNA precursor family (888 words) [view diff] no match in snippet view article find links to article
Chen HC, Fang LR (June 2011). "miR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kappaB". The
ADAM17 (2,387 words) [view diff] no match in snippet view article find links to article
activity may contribute to COVID-19 inflammation by cleavage of TNF-α and Interleukin-6 receptor. GRCh38: Ensembl release 89: ENSG00000151694 – Ensembl, May
HMGB4 (229 words) [view diff] no match in snippet view article find links to article
regulation of autophagy developmental process positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
Yoon Bo-hyun (1,019 words) [view diff] no match in snippet view article find links to article
BH; Romero, R; Yang, SH; Jun, JK; Kim, IO; Choi, JH; Syn, HC (1996). "Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with
Toll-like receptor 9 (2,551 words) [view diff] no match in snippet view article find links to article
process positive regulation of JUN kinase activity negative regulation of interleukin-6 production I-kappaB phosphorylation positive regulation of JNK cascade
Erdheim–Chester disease (2,228 words) [view diff] no match in snippet view article find links to article
(2003). "Biochemical markers of bone turnover, serum levels of interleukin-6/interleukin-6 soluble receptor and bisphosphonate treatment in Erdheim-Chester
Sialidase-3 (1,122 words) [view diff] no match in snippet view article find links to article
membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility". J. Biol. Chem. 281
Ian M. Kerr (222 words) [view diff] exact match in snippet view article find links to article
"Phosphotyrosine profiling to identify novel components of interferon and interleukin 6-family cytokine signalling". Proteomics. 1 (6): 767–772. doi:10
Hepatocyte growth factor (2,711 words) [view diff] no match in snippet view article find links to article
arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor". The Journal of
Eriocitrin (928 words) [view diff] no match in snippet view article find links to article
hemoglobin (−2%), glucagon (−6.5%), C-peptide (−5%), hsCRP (−12%), interleukin-6 (−13%), TNFα (−11%), lipid peroxidation (−17%), systolic blood pressure
Mevalonate kinase deficiency (1,889 words) [view diff] exact match in snippet view article find links to article
also produce higher levels of tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6) other than IL-Iβ During febrile (fever) attacks, C-reactive protein
Mir-370 microRNA precursor family (1,005 words) [view diff] no match in snippet view article find links to article
Patel T (January 2008). "Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes". Oncogene. 27 (3): 378–86. doi:10
ZBTB20 (567 words) [view diff] no match in snippet view article find links to article
gene expression transcription, DNA-templated positive regulation of interleukin-6 production positive regulation of interferon-beta production positive
Claire Greenhill (296 words) [view diff] no match in snippet view article find links to article
Philip R. Taylor, Brendan J. Jenkins, Nicholas Topley, Simon A. Jones, Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation, Immunity, Volume
LILRA2 (697 words) [view diff] no match in snippet view article find links to article
pathway granulocyte macrophage colony-stimulating factor production interleukin-6 production interleukin-8 production negative regulation of toll-like
POLD2 (899 words) [view diff] exact match in snippet view article find links to article
H, Tan CK, Downey KM, So AG (2001). "A tumor necrosis factor α- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase
PYCARD (1,338 words) [view diff] no match in snippet view article find links to article
Gene ontology Molecular function protein homodimerization activity interleukin-6 receptor binding BMP receptor binding protein binding identical protein
C1QTNF4 (gene) (150 words) [view diff] no match in snippet view article
signaling receptor activity positive regulation of interleukin-6 production positive regulation of interleukin-6-mediated signaling pathway positive regulation
FOXA3 (995 words) [view diff] exact match in snippet view article find links to article
nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T
ZCCHC6 (718 words) [view diff] no match in snippet view article find links to article
microRNA through uridylation. Genetic Inactivation of ZCCHC6 Suppresses Interleukin-6 Expression and Reduces the Severity of Experimental Osteoarthritis in
B3GAT1 (1,387 words) [view diff] exact match in snippet view article find links to article
"Function and molecular modeling of the interaction between human interleukin 6 and its HNK-1 oligosaccharide ligands". The Journal of Biological Chemistry
Toll-like receptor 8 (1,091 words) [view diff] no match in snippet view article find links to article
receptor signaling pathway toll-like receptor 8 signaling pathway immune response positive regulation of interleukin-6 production Sources:Amigo / QuickGO
PRKAG2 (1,084 words) [view diff] exact match in snippet view article find links to article
P, et al. (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
Diethylamino hydroxybenzoyl hexyl benzoate (284 words) [view diff] no match in snippet view article find links to article
UVA1-induced expression of matrix metalloproteinase-1, interleukin-1, and interleukin-6 in human dermal fibroblasts". Photochem Photobiol Sci. 5 (3): 275–82
Calpain-2 catalytic subunit (1,088 words) [view diff] no match in snippet view article find links to article
positive regulation of cardiac muscle cell apoptotic process regulation of interleukin-6 production cellular response to interferon-beta response to hydrogen
PTPRE (1,046 words) [view diff] no match in snippet view article find links to article
PTPepsilon C inhibits Jak-STAT signaling and differentiation induced by interleukin-6 and leukemia inhibitory factor in M1 leukemia cells". J. Biol. Chem
Proliferative vitreoretinopathy (1,471 words) [view diff] exact match in snippet view article find links to article
migration and its presence is also strongly detected in retinal membranes. Interleukin 6 levels are elevated in the vitreous humor during PVR. Leaver PK (1995)
Velamentous cord insertion (2,872 words) [view diff] no match in snippet view article find links to article
frequently assessed for high levels of inflammatory markers such as interleukin-6 which can indicate intra-amniotic inflammation. Upon diagnosis of velamentous
PRKACG (1,051 words) [view diff] exact match in snippet view article find links to article
Hofman F (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
PRKAG1 (1,137 words) [view diff] exact match in snippet view article find links to article
Hofman F (July 1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
Toll-like receptor 3 (1,057 words) [view diff] no match in snippet view article find links to article
production cellular response to exogenous dsRNA positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production cellular
Macrolide (2,804 words) [view diff] no match in snippet view article find links to article
1991). "Differential modulation of cytokine production by macrolides: interleukin-6 production is increased by spiramycin and erythromycin". Antimicrobial
UBE2Z (1,021 words) [view diff] exact match in snippet view article find links to article
Watanabe S, Yamada Y (April 2015). "Association of a polymorphism of the interleukin 6 receptor gene with chronic kidney disease in Japanese individuals".
Alpha-1B adrenergic receptor (1,333 words) [view diff] no match in snippet view article find links to article
1-adrenergic receptor subtypes by oligonucleotide microarrays: coupling to interleukin-6 secretion but differences in STAT3 phosphorylation and gp-130". Mol
NLRC3 (243 words) [view diff] no match in snippet view article find links to article
perinuclear region of cytoplasm Biological process negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production I-kappaB
Melanocortin 5 receptor (1,510 words) [view diff] exact match in snippet view article find links to article
Kim J, Suh PG, Ryu SH, Kim KT (April 2010). "Melanocortins induce interleukin 6 gene expression and secretion through melanocortin receptors 2 and 5
BMX (gene) (1,196 words) [view diff] exact match in snippet view article
is an effector of phosphatidylinositol 3′-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells". Proc
PRKD3 (1,073 words) [view diff] exact match in snippet view article find links to article
P, et al. (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
FER (gene) (968 words) [view diff] no match in snippet view article
chemotaxis protein phosphorylation Fc-epsilon receptor signaling pathway interleukin-6-mediated signaling pathway response to lipopolysaccharide cell adhesion
PRKD3 (1,073 words) [view diff] exact match in snippet view article find links to article
P, et al. (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article
Hofman F (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
RELB (1,560 words) [view diff] exact match in snippet view article find links to article
Giordano V, Baldassarre F, et al. (March 1994). "The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein".
SB-215505 (435 words) [view diff] no match in snippet view article find links to article
in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production
FOXA2 (1,550 words) [view diff] no match in snippet view article find links to article
transcription, DNA-templated positive regulation of gastrulation response to interleukin-6 positive regulation of transcription from RNA polymerase II promoter
PCK1 (1,026 words) [view diff] no match in snippet view article find links to article
response to hypoxia cellular response to fructose stimulus response to interleukin-6 glucose metabolic process human ageing response to methionine cellular
PTPRC (1,752 words) [view diff] no match in snippet view article find links to article
Tsuyama N, Abroun S, Liu S, Li FJ, Otsuyama K, et al. (September 2003). "Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation". Leukemia &
LPAR6 (1,014 words) [view diff] no match in snippet view article find links to article
PMID 15489334. Ihara H, Hirukawa K, Goto S, Togari A (2005). "ATP-stimulated interleukin-6 synthesis through P2Y receptors on human osteoblasts". Biochem. Biophys
Prostacyclin synthase (1,212 words) [view diff] no match in snippet view article find links to article
positive regulation of execution phase of apoptosis cellular response to interleukin-6 lipid metabolism icosanoid metabolic process cyclooxygenase pathway
Farber disease (1,401 words) [view diff] no match in snippet view article find links to article
disease. Anti-inflammatory medications, specifically tocilizumab (an interleukin-6 receptor inhibitor), has been shown to improve inflammation and pain
PRKCH (1,139 words) [view diff] exact match in snippet view article find links to article
P, et al. (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
KCTD13 (374 words) [view diff] exact match in snippet view article find links to article
Downey KM, So AG (October 2001). "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase
Leukemia inhibitory factor receptor (1,325 words) [view diff] exact match in snippet view article find links to article
(April 1994). "Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of
MMP8 (1,249 words) [view diff] no match in snippet view article find links to article
negative regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of DNA binding positive regulation of
CEBPA (1,473 words) [view diff] no match in snippet view article find links to article
positive regulation of macrophage activation positive regulation of inflammatory response interleukin-6-mediated signaling pathway Sources:Amigo / QuickGO
P-selectin glycoprotein ligand-1 (1,456 words) [view diff] no match in snippet view article find links to article
membrane plasma membrane raft Biological process cellular response to interleukin-6 leukocyte adhesive activation viral entry into host cell viral process
Arecoline (1,978 words) [view diff] exact match in snippet view article find links to article
respectively. It causes Oral Submucous Fibrosis by stimulating collagen, interleukin 6, keratinocyte growth factor-1, IGF-1, cystatin C, tissue inhibitor of
SLAMF1 (2,008 words) [view diff] no match in snippet view article find links to article
proliferation T-helper 1 cell cytokine production negative regulation of interleukin-6 production positive regulation of JNK cascade cell adhesion negative
SLAMF1 (2,008 words) [view diff] no match in snippet view article find links to article
proliferation T-helper 1 cell cytokine production negative regulation of interleukin-6 production positive regulation of JNK cascade cell adhesion negative
SOCS5 (726 words) [view diff] no match in snippet view article find links to article
differentiation negative regulation of signal transduction negative regulation of interleukin-6 production negative regulation of inflammatory response cellular response
LTBP1 (gene) (1,023 words) [view diff] exact match in snippet view article
postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression". Clin. Cancer
TICAM1 (616 words) [view diff] no match in snippet view article find links to article
transcription factor activity defense response to virus positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
SPI1 (1,741 words) [view diff] no match in snippet view article find links to article
through association with two transcription factors, nuclear factor-interleukin-6 and Spi-1". Blood. 90 (8): 3142–3153. doi:10.1182/blood.V90.8.3142.
RAB7B (411 words) [view diff] no match in snippet view article find links to article
regulation of toll-like receptor 4 signaling pathway positive regulation of interleukin-6 production cellular response to interferon-gamma intracellular protein
Swietenia macrophylla (1,503 words) [view diff] no match in snippet view article find links to article
(iNOS), cyclooxygenase-2 (COX-2), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6). SMEAF inhibited nuclear translocation of nuclear factor-kappa
Farnesoid X receptor (1,979 words) [view diff] no match in snippet view article find links to article
regulation of tumor necrosis factor production negative regulation of interleukin-6 production triglyceride homeostasis negative regulation of interferon-gamma
Toll-like receptor 7 (1,264 words) [view diff] no match in snippet view article find links to article
mechanical stimulus microglial cell activation positive regulation of interleukin-6 production MyD88-dependent toll-like receptor signaling pathway signal
Bemotrizinol (587 words) [view diff] no match in snippet view article find links to article
UVA1-induced expression of matrix metalloproteinase-1, interleukin-1, and interleukin-6 in human dermal fibroblasts". Photochem Photobiol Sci. 5 (3): 275–82
Periodic fever, aphthous stomatitis, pharyngitis and adenitis (880 words) [view diff] exact match in snippet view article find links to article
chemokines (IP-10/CXCL10, MIG/CXCL9), G-CSF and proinflammatory cytokines (interleukin 6, interleukin 18). Flares also manifest with a relative lymphopenia.
ICAM-1 (2,409 words) [view diff] no match in snippet view article find links to article
insulin cellular response to interferon-gamma cellular response to interleukin-6 cellular response to dexamethasone stimulus establishment of endothelial
Glucocerebrosidase (2,001 words) [view diff] no match in snippet view article find links to article
testosterone cellular response to starvation negative regulation of interleukin-6 production response to thyroid hormone ceramide biosynthetic process
Multiple organ dysfunction syndrome (1,914 words) [view diff] no match in snippet view article find links to article
mediators are: tumor necrosis factor-alpha (TNF-α), interleukin-1, interleukin-6, thromboxane A2, prostacyclin, platelet activating factor, and nitric
RNF14 (1,058 words) [view diff] no match in snippet view article find links to article
(2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells"
Fibroblast growth factor receptor 4 (1,289 words) [view diff] no match in snippet view article find links to article
Paillard V, Saunders M (1996). "Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction". J. Biol. Chem. 271 (11): 5961–4
IRAK3 (708 words) [view diff] no match in snippet view article find links to article
negative regulation of protein catabolic process negative regulation of interleukin-6 production interleukin-1-mediated signaling pathway positive regulation
Fibroblast growth factor 23 (1,854 words) [view diff] no match in snippet view article find links to article
differentiation negative regulation of bone mineralization cellular response to interleukin-6 vitamin D metabolic process regulation of bone mineralization phosphate
Adenosine A2B receptor (2,090 words) [view diff] no match in snippet view article find links to article
activity cellular defense response JNK cascade positive regulation of interleukin-6 production relaxation of vascular associated smooth muscle positive
KLF2 (2,219 words) [view diff] no match in snippet view article find links to article
regulation of nitric oxide biosynthetic process negative regulation of interleukin-6 production cellular response to tumor necrosis factor cellular response
AKIRIN2 (319 words) [view diff] no match in snippet view article find links to article
regulation of cell population proliferation positive regulation of interleukin-6 production positive regulation of transcription by RNA polymerase II
Genentech (3,361 words) [view diff] no match in snippet view article find links to article
day the product was approved. 2010: Actemra (tocilizumab): The first interleukin-6 (IL-6) receptor-inhibiting monoclonal antibody approved to treat rheumatoid
Genentech (3,361 words) [view diff] no match in snippet view article find links to article
day the product was approved. 2010: Actemra (tocilizumab): The first interleukin-6 (IL-6) receptor-inhibiting monoclonal antibody approved to treat rheumatoid
PTK2B (1,887 words) [view diff] no match in snippet view article find links to article
Anderson KC (September 2000). "SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells".
Fibrinogen gamma chain (471 words) [view diff] no match in snippet view article find links to article
maturation cellular response to interleukin-1 cellular response to interleukin-6 negative regulation of platelet aggregation post-translational protein
Epigenetics of schizophrenia (5,482 words) [view diff] exact match in snippet view article find links to article
the onset of schizophrenia, as seen in studies in which amounts of interleukin 6 and interleukin 10, pro- and anti- inflammatory, respectively, were
Multidrug resistance-associated protein 2 (1,709 words) [view diff] no match in snippet view article find links to article
lipopolysaccharide cellular response to interleukin-1 cellular response to interleukin-6 cellular response to tumor necrosis factor cellular response to dexamethasone
NetPath (755 words) [view diff] no match in snippet view article find links to article
pathway Interleukin-3 pathway Interleukin-4 pathway Interleukin-5 pathway Interleukin-6 pathway Interleukin-7 pathway Interleukin-9 pathway The cancer signaling
Beneficial Microbes (739 words) [view diff] no match in snippet view article find links to article
The overall experiment revealed a sharp decrease in the production of interleukin-6 and interleukin-1β when grown ex vivo, which will lead to potential
Prohibitin (2,386 words) [view diff] no match in snippet view article find links to article
process regulation of transcription, DNA-templated cellular response to interleukin-6 negative regulation of protein catabolic process negative regulation
Evolution of schizophrenia (3,380 words) [view diff] no match in snippet view article find links to article
Zhang PY, Wu GY, Cao LY, Shen YC (2002). "Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: Association
NFKB1 (2,363 words) [view diff] no match in snippet view article find links to article
lumen specific granule lumen Biological process cellular response to interleukin-6 positive regulation of canonical Wnt signaling pathway regulation of
HSF1 (2,447 words) [view diff] exact match in snippet view article find links to article
IL-1beta gene through physical interaction with the nuclear factor of interleukin 6". The Journal of Biological Chemistry. 277 (14): 11802–10. doi:10.1074/jbc
CTR9 (475 words) [view diff] no match in snippet view article find links to article
pathway transcription, DNA-templated stem cell population maintenance interleukin-6-mediated signaling pathway endodermal cell fate commitment positive
MAPK1 (2,322 words) [view diff] no match in snippet view article find links to article
gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6". FEBS Lett. 401 (2–3): 133–7. doi:10.1016/s0014-5793(96)01456-1. PMID 9013873
Arrestin beta 1 (1,584 words) [view diff] no match in snippet view article find links to article
activity involved in apoptotic process endocytosis negative regulation of interleukin-6 production positive regulation of histone acetylation negative regulation
Clusterin (2,433 words) [view diff] no match in snippet view article find links to article
Fabiola S, Boothman DA, David BA, Spagnoli LG, Luigi SG (Feb 2009). "Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin
Thymic stromal lymphopoietin (2,415 words) [view diff] no match in snippet view article find links to article
positive regulation of interleukin-5 production positive regulation of interleukin-6 production positive regulation of mast cell activation positive regulation
MYD88 (2,250 words) [view diff] no match in snippet view article find links to article
stimulus regulation of inflammatory response positive regulation of interleukin-6 production positive regulation of I-kappaB kinase/NF-kappaB signaling
AZI2 (547 words) [view diff] no match in snippet view article find links to article
function protein binding Cellular component cytoplasm Biological process interleukin-6 production dendritic cell differentiation cytokine production tumor
Cholesterol crystal (494 words) [view diff] no match in snippet view article find links to article
PMC 3623938. PMID 23412688. Ridker PM (2016). "From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection"
Cholesterol crystal (494 words) [view diff] no match in snippet view article find links to article
PMC 3623938. PMID 23412688. Ridker PM (2016). "From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection"
Etomidate (3,311 words) [view diff] no match in snippet view article find links to article
in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 levels and intubation with etomidate on adrenal function and mortality"
AZI2 (547 words) [view diff] no match in snippet view article find links to article
function protein binding Cellular component cytoplasm Biological process interleukin-6 production dendritic cell differentiation cytokine production tumor
PTPN6 (2,292 words) [view diff] no match in snippet view article find links to article
dephosphorylation cytokine-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production cellular
NOD2 (1,547 words) [view diff] no match in snippet view article find links to article
production regulation of inflammatory response positive regulation of interleukin-6 production protein complex oligomerization positive regulation of tumor
NLRX1 (818 words) [view diff] no match in snippet view article find links to article
membrane cell junction cytoplasm Biological process negative regulation of interleukin-6 production negative regulation of type I interferon production viral
Nuclear receptor coactivator 1 (1,699 words) [view diff] no match in snippet view article find links to article
(Oct 2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells"
Teleost leptins (3,213 words) [view diff] exact match in snippet view article find links to article
1996). "The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors". Proceedings of the National Academy of Sciences
NOD1 (937 words) [view diff] no match in snippet view article find links to article
positive regulation of ERK1 and ERK2 cascade positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
Castleman disease (2,400 words) [view diff] no match in snippet view article find links to article
recommended. If symptoms are due to an inflammatory syndrome, then anti-interleukin-6 (IL-6) therapy is recommended. If these treatments are not effective
FOXP3 (3,448 words) [view diff] no match in snippet view article find links to article
RNA polymerase II regulation of T cell anergy negative regulation of interleukin-6 production tolerance induction to self antigen regulation of transcription
Avobenzone (2,308 words) [view diff] no match in snippet view article find links to article
UVA1-induced expression of matrix metalloproteinase-1, interleukin-1, and interleukin-6 in human dermal fibroblasts". Photochem Photobiol Sci. 5 (3): 275–282
Toll-like receptor 4 (9,082 words) [view diff] no match in snippet view article find links to article
proliferation defense response to bacterium positive regulation of interleukin-6 production activation of innate immune response positive regulation
List of human endocrine organs and actions (687 words) [view diff] no match in snippet view article find links to article
(October 2008). "Muscle as an endocrine organ: focus on muscle-derived interleukin-6". Physiological Reviews. 88 (4): 1379–406. doi:10.1152/physrev.90100
Exerkine (756 words) [view diff] no match in snippet view article find links to article
"Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6". The Journal
DIO2 (1,084 words) [view diff] no match in snippet view article find links to article
"Inhibition of type 2,5'-deiodinase by tumor necrosis factor alpha, interleukin-6 and interferon gamma in human thyroid tissue". Immunol. Lett. 80 (1):
Neuromyelitis optica spectrum disorder (7,255 words) [view diff] no match in snippet view article find links to article
completely known. Some reports point to the metalloproteinase-2 and interleukin-6 as culprits responsible for the BBB failure. There is broad consensus
HMGB1 (3,154 words) [view diff] no match in snippet view article find links to article
positive regulation of interferon-beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
Cyclooxygenase-1 (2,122 words) [view diff] no match in snippet view article find links to article
vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element". The Journal of Biological
Conjunctivochalasis (988 words) [view diff] no match in snippet view article find links to article
Mocan MC, Bozkurt B, Gariboglu S, Irkec M, Orhan M. Elevated tear Interleukin-6 and Interleukin-8 in patients with Conjunctivochalasis Cornea. 2009
Janus kinase 2 (3,166 words) [view diff] no match in snippet view article find links to article
cytokine-mediated signaling pathway interleukin-23-mediated signaling pathway interleukin-6-mediated signaling pathway interleukin-27-mediated signaling pathway
CITED1 (779 words) [view diff] no match in snippet view article find links to article
response to interleukin-4 response to interferon-gamma response to interleukin-6 placenta development regulation of transcription by RNA polymerase II
CITED1 (779 words) [view diff] no match in snippet view article find links to article
response to interleukin-4 response to interferon-gamma response to interleukin-6 placenta development regulation of transcription by RNA polymerase II
RAD23B (1,848 words) [view diff] no match in snippet view article find links to article
silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells". The Journal of Biological
RIPK2 (965 words) [view diff] no match in snippet view article find links to article
regulation of alpha-beta T cell proliferation positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
AP-1 transcription factor (4,407 words) [view diff] exact match in snippet view article find links to article
2005). "Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein
Ruth Stephens Gani Medal (452 words) [view diff] no match in snippet view article find links to article
largest asthma genetics study in Australia; identified a gene – the interleukin-6 receptor – that has a more active version and a less active version
Arrestin beta 2 (1,962 words) [view diff] no match in snippet view article find links to article
of release of cytochrome c from mitochondria negative regulation of interleukin-6 production receptor internalization transcription by RNA polymerase
Siderophore (5,316 words) [view diff] no match in snippet view article find links to article
and macrophages. Infection leads to inflammation and the release of interleukin-6 (IL-6 ) which stimulates hepcidin expression. In humans, IL-6 production
LMO4 (925 words) [view diff] no match in snippet view article find links to article
Novotny-Diermayr V, Lin B, Gu L, Cao X (2005). "Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4
Mir-10 microRNA precursor family (3,499 words) [view diff] no match in snippet view article find links to article
endometriotic cells via dysregulation of the proteolytic milieu and interleukin-6 secretion". Fertility and Sterility. 99 (3): 871–881.e1. doi:10.1016/j
COVID-19 drug development (13,107 words) [view diff] no match in snippet view article find links to article
multiple countries mid-2020 Sarilumab human monoclonal antibody against interleukin-6 receptor rheumatoid arthritis (US, Europe) Regeneron-Sanofi Multiple
Ganesan Venkatasubramanian (1,598 words) [view diff] no match in snippet view article find links to article
DA, Maitra A, Ravi V, Gangadhar BN (May 2014). "Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia:
ZMYM2 (967 words) [view diff] no match in snippet view article find links to article
ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors". The Journal of Biological Chemistry. 278 (18):
5-HT2B receptor (3,702 words) [view diff] no match in snippet view article find links to article
in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production
Adrenocortical hormone (1,516 words) [view diff] no match in snippet view article find links to article
al., it was concluded that GABA-1 transcription factor activates the interleukin-6-gene. This gene codes for a protein that activates the inflammatory
Lipopolysaccharide binding protein (1,454 words) [view diff] no match in snippet view article find links to article
positive regulation of interleukin-8 production positive regulation of interleukin-6 production positive regulation of neutrophil chemotaxis positive regulation
Apparent death (5,487 words) [view diff] no match in snippet view article find links to article
Kulikov, A.V.; Popova, N.K. (2011). "Effects of lipopolysaccharide and interleukin-6 on cataleptic immobility and locomotor activity in mice". Neuroscience
CD47 (4,164 words) [view diff] no match in snippet view article find links to article
interleukin-10 production regulation of interleukin-12 production regulation of interleukin-6 production regulation of tumor necrosis factor production heterotypic
Saururus chinensis (557 words) [view diff] no match in snippet view article find links to article
Mun-Chual (2011). "Manassantin A and B From Saururus chinensis Inhibit Interleukin-6–Induced Signal Transducer and Activator of Transcription 3 Activation
SRA1 (1,467 words) [view diff] no match in snippet view article find links to article
(October 2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells"
Mothers against decapentaplegic homolog 4 (3,464 words) [view diff] no match in snippet view article find links to article
acetylation regulation of transforming growth factor beta2 production interleukin-6-mediated signaling pathway negative regulation of transcription by RNA
VAV1 (1,999 words) [view diff] no match in snippet view article find links to article
gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6". FEBS Lett. 401 (2–3): 133–7. doi:10.1016/s0014-5793(96)01456-1. PMID 9013873
Aphthous stomatitis (5,223 words) [view diff] no match in snippet view article find links to article
adrenal steroids and reduce production of TNF-α, interleukin-1 and interleukin-6. Smokeless tobacco products also seem to protect against aphthous stomatitis
Brain natriuretic peptide 32 (4,329 words) [view diff] no match in snippet view article find links to article
stimulated by pro-inflammatory cell factors, such as interleukin-1β, interleukin-6 and tumor necrosis factor-α. Dilates the afferent glomerular arteriole
Vanadium (8,468 words) [view diff] no match in snippet view article find links to article
(2006). "Pentavalent vanadium induces hepatic metallothionein through interleukin-6-dependent and -independent mechanisms". Toxicology. 228 (2–3): 162–170
Carmela Abraham (719 words) [view diff] exact match in snippet view article find links to article
"Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6". Proceedings of the National Academy of Sciences of the United States
List of human clusters of differentiation (467 words) [view diff] no match in snippet view article find links to article
Interleukin-5 receptor subunit alpha; encoded by IL5RA gene. CD126 Interleukin-6 receptor subunit alpha; encoded by IL6R gene. CD127 the IL-7 receptor
CBL (gene) (3,814 words) [view diff] no match in snippet view article
negative regulation of neuron death cytokine-mediated signaling pathway interleukin-6-mediated signaling pathway ubiquitin-dependent protein catabolic process
List of human clusters of differentiation (467 words) [view diff] no match in snippet view article find links to article
Interleukin-5 receptor subunit alpha; encoded by IL5RA gene. CD126 Interleukin-6 receptor subunit alpha; encoded by IL6R gene. CD127 the IL-7 receptor
CBL (gene) (3,814 words) [view diff] no match in snippet view article
negative regulation of neuron death cytokine-mediated signaling pathway interleukin-6-mediated signaling pathway ubiquitin-dependent protein catabolic process
Impact of the COVID-19 pandemic on neurological, psychological and other mental health outcomes (6,242 words) [view diff] no match in snippet view article find links to article
the antiviral response to COVID-19, including the NLRP3 inflammasome, interleukin-6, and ACE-2. Reported prevalence of mental health disorders vary depending
HLA-B (1,889 words) [view diff] no match in snippet view article find links to article
of immune response regulation of T cell anergy viral process regulation of interleukin-6 production neutrophil degranulation Sources:Amigo / QuickGO
PRKAR1B (1,189 words) [view diff] exact match in snippet view article find links to article
Hofman F (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
GAS6 (1,270 words) [view diff] no match in snippet view article find links to article
transmembrane transport cell-substrate adhesion negative regulation of interleukin-6 production positive regulation of dendritic cell chemotaxis signal peptide
PPARGC1A (3,322 words) [view diff] no match in snippet view article find links to article
regulation of glycolytic process response to fructose cellular response to interleukin-6 rhythmic process cellular response to resveratrol response to thyroid
Giovanna Tosato (623 words) [view diff] no match in snippet view article find links to article
started. Tosato, G; Jones, Kd (March 1990). "Interleukin-1 induces interleukin-6 production in peripheral blood monocytes". Blood. 75 (6): 1305–1310
Lupus (13,042 words) [view diff] exact match in snippet view article find links to article
B-lymphocyte stimulator (BLyS), also known as B-cell activating factor (BAFF), interleukin 6, interleukin 17, interleukin 18, type I interferons, and tumor necrosis
ARHGEF2 (1,134 words) [view diff] no match in snippet view article find links to article
establishment of mitotic spindle orientation positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive
Cerebritis (923 words) [view diff] no match in snippet view article find links to article
of neutrophils in brain tissue. Two cytokines, interferon alpha and interleukin-6, have been found in the CSF of SLE patients with psychosis. However
PRKAR2B (1,406 words) [view diff] exact match in snippet view article find links to article
Hofman F (Jul 1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase
GSTA4 (1,100 words) [view diff] no match in snippet view article find links to article
(2002). "Pro-inflammatory cytokines tumor necrosis factor alpha and interleukin-6 and survival factor epidermal growth factor positively regulate the
Teratocarcinoma-derived growth factor 1 (902 words) [view diff] no match in snippet view article find links to article
region Biological process cell differentiation cellular response to interleukin-6 epidermal growth factor receptor signaling pathway somatic stem cell
ORM1 (982 words) [view diff] no match in snippet view article find links to article
collagen-containing extracellular matrix Biological process negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production regulation
FTH1 (1,349 words) [view diff] no match in snippet view article find links to article
PMID 7931301. S2CID 22225445. Rogers JT (March 1996). "Ferritin translation by interleukin-6: the role of sequences upstream of the start codons of the heavy and
Beta-2 microglobulin (2,117 words) [view diff] no match in snippet view article find links to article
Klein B (November 1992). "Serum levels of beta 2 microglobulin and interleukin-6 to differentiate monoclonal gammopathy of undetermined significance"
ZC3H12A (189 words) [view diff] no match in snippet view article find links to article
cell death positive regulation of autophagy negative regulation of interleukin-6 production positive regulation of lipid storage negative regulation
CD36 (5,085 words) [view diff] no match in snippet view article find links to article
regulation of cytosolic calcium ion concentration positive regulation of interleukin-6 production positive regulation of peptidyl-tyrosine phosphorylation
Entolimod (1,044 words) [view diff] no match in snippet view article find links to article
2012). "Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure"
FNDC5 (2,181 words) [view diff] no match in snippet view article find links to article
(October 2008). "Muscle as an endocrine organ: focus on muscle-derived interleukin-6". Physiological Reviews. 88 (4): 1379–406. doi:10.1152/physrev.90100
FCER1G (612 words) [view diff] no match in snippet view article find links to article
regulation of mast cell cytokine production positive regulation of interleukin-6 production regulation of immune response positive regulation of tumor
Proteases in angiogenesis (5,423 words) [view diff] no match in snippet view article find links to article
progenitor cells, and the shedding of interleukin-6 receptors by ADAM10 and ADAM17 which facilitates interleukin-6 signaling in endothelial cells. Semaphorin
Phosphotyrosine interaction domain containing 1 (551 words) [view diff] no match in snippet view article find links to article
negative regulation of protein phosphorylation cellular response to interleukin-6 cellular response to tumor necrosis factor regulation of reactive oxygen
HSP90AB1 (3,113 words) [view diff] no match in snippet view article find links to article
Matsuda T (Jan 2003). "Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3". Biochemical and Biophysical
Proteases in angiogenesis (5,423 words) [view diff] no match in snippet view article find links to article
progenitor cells, and the shedding of interleukin-6 receptors by ADAM10 and ADAM17 which facilitates interleukin-6 signaling in endothelial cells. Semaphorin
DNA vaccine (8,381 words) [view diff] exact match in snippet view article find links to article
motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma". Proceedings of the National
RELA (6,578 words) [view diff] no match in snippet view article find links to article
response to amino acid response to interleukin-1 cellular response to interleukin-6 response to progesterone response to organic substance Fc-epsilon receptor
Shift-and-persist model (3,693 words) [view diff] no match in snippet view article find links to article
Mary; Love, Gayle D.; Singer, Burton H.; Ryff, Carol D. (2007). "Plasma interleukin-6 and soluble IL-6 receptors are associated with psychological well-being
Phosphotyrosine interaction domain containing 1 (551 words) [view diff] no match in snippet view article find links to article
negative regulation of protein phosphorylation cellular response to interleukin-6 cellular response to tumor necrosis factor regulation of reactive oxygen
Proliferating cell nuclear antigen (6,158 words) [view diff] exact match in snippet view article find links to article
Downey KM, So AG (October 2001). "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase
ERAP1 (4,773 words) [view diff] no match in snippet view article find links to article
Hawari F, Levine SJ (2003). "An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding". Journal of Biological Chemistry. 278 (31): 28677–85
Group 5 element (8,537 words) [view diff] no match in snippet view article find links to article
(2006). "Pentavalent vanadium induces hepatic metallothionein through interleukin-6-dependent and -independent mechanisms". Toxicology. 228 (2–3): 162–170
Rabbit hybridoma (1,279 words) [view diff] no match in snippet view article find links to article
Liguori MJ, Hoff-Velk JA, Ostrow DH (June 2001). "Recombinant human interleukin-6 enhances the immunoglobulin secretion of a rabbit-rabbit hybridoma"
Arsenic poisoning (9,442 words) [view diff] no match in snippet view article find links to article
Andrikopoulos S, Koukoulas I, Proietto J, Febbraio MA (March 2003). "Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle
Urocortin (2,194 words) [view diff] no match in snippet view article find links to article
cardiac muscle contraction feeding behavior positive regulation of interleukin-6 production response to auditory stimulus learning or memory social behavior
Ferritin light chain (1,879 words) [view diff] no match in snippet view article find links to article
PMID 8554925. Rogers JT (March 1996). "Ferritin translation by interleukin-6: the role of sequences upstream of the start codons of the heavy and
Cedillo v. Secretary of Health and Human Services (5,362 words) [view diff] no match in snippet view article find links to article
(2006). "Uncoupling of ATP-Mediated Calcium Signaling and Dysregulated Interleukin-6 Secretion in Dendritic Cells by Nanomolar Thimerosal". Environmental
Beverly Mock (309 words) [view diff] exact match in snippet view article find links to article
Hilbert, D M; Kopf, M; Mock, B A; Köhler, G; Rudikoff, S (July 1, 1995). "Interleukin 6 is essential for in vivo development of B lineage neoplasms". Journal
TNFAIP3 (1,971 words) [view diff] no match in snippet view article find links to article
tumor necrosis factor-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of B cell activation negative regulation
Obesity-associated morbidity (5,053 words) [view diff] no match in snippet view article find links to article
Annette T.; Levy, Bruce D.; Israel, Elliot; et al. (July 2016). "Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional
Occupational health psychology (10,603 words) [view diff] exact match in snippet view article find links to article
Theorell, T.; Hasselhorn, H.; Vingård, E.; Andersson, B. (2000). "Interleukin 6 and cortisol in acute musculoskeletal disorders: Results from a case–referent
Childbirth (18,233 words) [view diff] no match in snippet view article find links to article
Morello R, Levy G, Ballet JJ (March 2000). "Fetal distress increases interleukin-6 and interleukin-8 and decreases tumour necrosis factor-alpha cord blood
Estrogen receptor alpha (6,357 words) [view diff] no match in snippet view article find links to article
PMID 9817600. Stein B, Yang MX (September 1995). "Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta"
ISL1 (1,484 words) [view diff] no match in snippet view article find links to article
regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production regulation
GroEL (5,438 words) [view diff] no match in snippet view article find links to article
immune response to tumor cell protein refolding positive regulation of interleukin-6 production positive regulation of apoptotic process response to cold
Attachment theory (22,213 words) [view diff] no match in snippet view article find links to article
attachment style produce higher levels of the pro inflammatory cytokine interleukin-6 (IL-6) when reacting to an interpersonal stressor, while individuals
Shalini Prasad (932 words) [view diff] no match in snippet view article find links to article
Simultaneous Measurement of Glial Fibrillary Acidic Protein (GFAP) and Interleukin-6 (IL-6) for Management of Traumatic Brain Injuries". Biosensors. 12 (12):
SELS (gene) (1,062 words) [view diff] no match in snippet view article
gluconeogenesis establishment of protein localization negative regulation of interleukin-6 production response to glucose negative regulation of glycogen biosynthetic
Elina Zúñiga (2,548 words) [view diff] no match in snippet view article find links to article
PMID 22704622; PMCID: PMC3377983. Harker JA, Lewis GM, Mack L, Zuniga EI. Late interleukin-6 escalates T follicular helper cell responses and controls a chronic
Carcinogenesis (13,948 words) [view diff] exact match in snippet view article find links to article
PMID 22951309. Nelson AM, Katseff AS, Ratliff TS, Garza LA (February 2016). "Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration"
RIG-I (2,831 words) [view diff] no match in snippet view article find links to article
positive regulation of interleukin-8 production positive regulation of interleukin-6 production negative regulation of type I interferon production detection
George P. Chrousos (1,401 words) [view diff] no match in snippet view article find links to article
Manolagas, S.C., Chrousos, G.P. (1998) The Pathophysiologic Roles of Interleukin-6 in Humans. Ann. Intern. Med. 128:127-137. [8] Gold, P.W., Goodwin, F
Albert P. Li (1,512 words) [view diff] exact match in snippet view article find links to article
Hepatic Differentiation: Results with the Model Pro-inflammatory Cytokine Interleukin 6. Drug Metabolism Letters 8(1), 12–18. Li, A. P. (2012) Editorial: metabolism