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Longer titles found: Integrin-like receptors (view), Integrin-linked kinase (view), Integrin alphaXbeta2 (view), Integrin alpha 1 (view), Integrin alpha 10 (view), Integrin alpha 11 (view), Integrin alpha 2 (view), Integrin alpha 2b (view), Integrin alpha 3 (view), Integrin alpha 4 (view), Integrin alpha 5 (view), Integrin alpha 6 (view), Integrin alpha 7 (view), Integrin alpha 8 (view), Integrin alpha 9 (view), Integrin alpha D (view), Integrin alpha L (view), Integrin alpha M (view), Integrin alpha V (view), Integrin alpha X (view), Integrin beta 1 (view), Integrin beta 2 (view), Integrin beta 3 (view), Integrin beta 4 (view), Integrin beta 5 (view), Integrin beta 6 (view), Integrin beta 7 (view), Integrin beta 8 (view), Integrin subunit beta like 1 (view), Disintegrin (view)

searching for Integrin 203 found (1169 total)

alternate case: integrin

EIF6 (1,718 words) [view diff] exact match in snippet view article find links to article

Eukaryotic translation initiation factor 6 (EIF6), also known as Integrin beta 4 binding protein (ITGB4BP), is a human gene. Hemidesmosomes are structures
Oxypertine (186 words) [view diff] exact match in snippet view article find links to article
Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia. It was also evaluated
ADAM2 (683 words) [view diff] exact match in snippet view article find links to article
JM (October 1999). "Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin alpha6beta1: implications for murine
Etaracizumab (235 words) [view diff] exact match in snippet view article find links to article
"Tumor-selective response to antibody-mediated targeting of alphavbeta3 integrin in ovarian cancer". Neoplasia. 10 (11): 1259–67. doi:10.1593/neo.08740
Collagen, type XVI, alpha 1 (597 words) [view diff] exact match in snippet view article find links to article
Niland S, Mörgelin M, Grifka J, Grässel S (2006). "Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains". J. Biol. Chem
Costamere (1,124 words) [view diff] exact match in snippet view article find links to article
dystrophin-glycoprotein complex (DGC) and the integrin-vinculin-talin complex. The sarcoglycans of the DGC and the integrins of the integrin-vinculin-talin complex attach
Tetraspanin (388 words) [view diff] exact match in snippet view article find links to article
exhibit impaired "outside-in" signalling through αIIbβ3, the major platelet integrin. it is hypothesized that tetraspanins interact with and regulate other
SIBLING proteins (211 words) [view diff] exact match in snippet view article find links to article
non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked glycoprotein, are components of the extracellular
HPS5 (622 words) [view diff] exact match in snippet view article find links to article
Hermansky–Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky–Pudlak syndrome
Leukocidin (291 words) [view diff] exact match in snippet view article find links to article
cytotoxin’s “S” subunit recognizes specific protein-containing receptors, or an integrin on the host cell’s surface. The S subunit then recruits a second, “F” subunit
ITGB1BP1 (1,167 words) [view diff] exact match in snippet view article find links to article
Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene. The cytoplasmic domains of integrins are essential for
ADAM23 (663 words) [view diff] exact match in snippet view article find links to article
neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. GRCh38: Ensembl release 89: ENSG00000114948 - Ensembl
Laminin, alpha 5 (1,307 words) [view diff] exact match in snippet view article find links to article
2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal
Dystonin (1,453 words) [view diff] exact match in snippet view article find links to article
2003). "Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly". Journal of Cell Science
CLCA2 (920 words) [view diff] exact match in snippet view article find links to article
Abdel-Ghany M, Cheng HC, Elble RC, Pauli BU (2001). "The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis". J. Biol. Chem. 276
FAM20C (815 words) [view diff] exact match in snippet view article find links to article
both casein and other highly acidic proteins and members of the small integrin-binding ligand, the N-linked glycoproteins (SIBLING) family at the target
CIB1 (1,205 words) [view diff] exact match in snippet view article find links to article
Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene. The protein encoded by this gene is a member of the calcium-binding
FERMT3 (1,494 words) [view diff] exact match in snippet view article find links to article
are responsible for cell to cell crosstalk via cell-cell contacts and integrin mediated cell adhesion through focal adhesion proteins and as specialised
Tirofiban (1,008 words) [view diff] exact match in snippet view article find links to article
of the protein-protein interaction between fibrinogen and the platelet integrin receptor GP IIb/IIIa and is the first drug candidate whose origins can
DMP1 (1,073 words) [view diff] exact match in snippet view article find links to article
phosphoprotein is an extracellular matrix protein and a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family (other members being
ACER2 (394 words) [view diff] exact match in snippet view article find links to article
plays an important role in regulating integrin β1 subunit (ITGB1) maturation and cell adhesion mediated by β1 integrins. GRCh38: Ensembl release 89: ENSG00000177076
Alveolar macrophage (3,809 words) [view diff] exact match in snippet view article find links to article
alveolar epithelial cells, thus inducing the expression of the αvβ6 integrin. Integrins are dimeric cell-surface receptors composed of alpha and beta subunits
Laminin, gamma 3 (850 words) [view diff] exact match in snippet view article find links to article
"Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3)". Clin. Exp. Metastasis. 19 (2): 127–34. doi:10.1023/A:1014573204062
GPR56 (3,013 words) [view diff] exact match in snippet view article find links to article
cerebral cortex. Next to GPR56, the α3β1 integrin is also involved in pial BM maintenance. Study from Itga3 (α3 integrin)/Gpr56 double knockout mice showed
Tensin (717 words) [view diff] exact match in snippet view article find links to article
of plasma membrane called integrin-mediated focal adhesions (which are formed around a transmembrane core of an αβ integrin heterodimer). Genome sequencing
Osteopontin (7,467 words) [view diff] exact match in snippet view article find links to article
thrombin-cleaved OPN (OPN-R) exposes an epitope for integrin receptors of α4β1, α9β1, and α9β4. These integrin receptors are present on a number of immune cells
PTK2B (1,876 words) [view diff] exact match in snippet view article find links to article
in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells". J. Biol. Chem. 272 (7): 4230–6.
EMID2 (377 words) [view diff] exact match in snippet view article find links to article
chromosomal localization of human alpha(11) integrin. A collagen-binding, I domain-containing, beta(1)-associated integrin alpha-chain present in muscle tissues"
Rap1 (1,162 words) [view diff] exact match in snippet view article find links to article
to membranes where integrins are found. This provides a mechanism by which Rap1 can act directly on integrins and modulate integrin affinity and/or clustering
List of MeSH codes (D12.776.395) (778 words) [view diff] exact match in snippet view article
395.550.625.298 – integrin alpha2beta1 MeSH D12.776.395.550.625.379 – integrin alpha5beta1 MeSH D12.776.395.550.625.419 – integrin alpha6beta1 MeSH D12
TGF beta Activation (2,407 words) [view diff] exact match in snippet view article find links to article
integrins to participate in latent TGF-β1 activation, arose from studies that examined mutations/knockouts of β6 integrin, αV integrin, β8 integrin and
TSPAN4 (662 words) [view diff] exact match in snippet view article find links to article
sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced
ADAM11 (537 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • integrin binding • metalloendopeptidase activity • metallopeptidase activity Cellular component • GO:0005578 extracellular
Laminin, alpha 3 (1,230 words) [view diff] exact match in snippet view article find links to article
Weitzman S, Jones JC (1999). "A Cell Signal Pathway Involving Laminin-5, α3β1 Integrin, and Mitogen-activated Protein Kinase Can Regulate Epithelial Cell Proliferation"
ADAM28 (603 words) [view diff] exact match in snippet view article find links to article
(2002). "The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1". J. Biol. Chem. 277 (5): 3784–3792. doi:10.1074/jbc.M109538200
ISG15 (2,487 words) [view diff] exact match in snippet view article find links to article
can be detected in supernatant or blood plasma. ISG15 binds the LFA-1 integrin receptor on NK- and T-cells to potentiate their production of IFN-II, which
PARVB (718 words) [view diff] exact match in snippet view article find links to article
PMID 10591208. Yamaji S, Suzuki A, Sugiyama Y, et al. (2001). "A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage
EMILIN1 (613 words) [view diff] exact match in snippet view article find links to article
PMID 11278945. Spessotto P, Cervi M, Mucignat MT, et al. (2003). "beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain". J
ITGB3BP (804 words) [view diff] exact match in snippet view article find links to article
polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol. 131 (3): 807–16. doi:10.1083/jcb.131.3.807
TSPAN32 (522 words) [view diff] exact match in snippet view article find links to article
function Cellular component • integral component of membrane • cell surface • integrin alphaIIb-beta3 complex • integral component of plasma membrane • intracellular
Actinin alpha 3 (1,366 words) [view diff] exact match in snippet view article find links to article
1993). "Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin". Journal
Cilengitide (887 words) [view diff] exact match in snippet view article find links to article
based on the cyclic peptide cyclo(-RGDfV-), which is selective for αv integrins, which are important in angiogenesis (forming new blood vessels), and
PKC alpha (2,614 words) [view diff] exact match in snippet view article find links to article
SJ, Wright MO, Nuki G, Al-Jamal R, Salter DM (Nov 2002). "Activation of Integrin-RACK1/PKCalpha signalling in human articular chondrocyte mechanotransduction"
CLNS1A (1,143 words) [view diff] exact match in snippet view article find links to article
Sattler E, Harriott P, Cahill DJ, Moran N (Jun 2004). "ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation"
CXCL13 (514 words) [view diff] exact match in snippet view article find links to article
venule • positive regulation of integrin activation • positive regulation of cell-cell adhesion mediated by integrin • B cell chemotaxis • GO:0032861
Fibronectin binding protein A (694 words) [view diff] exact match in snippet view article find links to article
bind fibronectin present in the extracellular matrix. Similarly, the α5β1 integrin present on host cells also binds fibronectin to create a link to its actin
Fibrillin 1 (3,591 words) [view diff] case mismatch in snippet view article find links to article
Growth Factor-like Domains 1uzj: INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, HOLO FORM. 1uzk: INTEGRIN BINDING CBEGF22-TB4-CBEGF33
TENC1 (615 words) [view diff] exact match in snippet view article find links to article
(2003). "Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling"
Actinin alpha 4 (1,420 words) [view diff] exact match in snippet view article find links to article
Burridge K (1990). "An interaction between alpha-actinin and the beta 1 integrin subunit in vitro". J. Cell Biol. 111 (2): 721–9. doi:10.1083/jcb.111.2
Junctional epidermolysis bullosa (medicine) (996 words) [view diff] exact match in snippet view article
infection. Hands and fingers may be affected, as well as various joints. α6β4 integrin is a transmembrane protein found in hemidesmosomes. As a heterodimer molecule
FERMT1 (838 words) [view diff] exact match in snippet view article find links to article
protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion". J. Biol. Chem. 279 (8): 6824–33. doi:10.1074/jbc.M307978200
PLK2 (742 words) [view diff] exact match in snippet view article find links to article
"The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity"
Receptor for activated C kinase 1 (2,586 words) [view diff] exact match in snippet view article find links to article
1998). "Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit". The Journal of Biological Chemistry. 273 (4): 2379–83. doi:10
Endostatin (2,556 words) [view diff] exact match in snippet view article find links to article
adhesions, cell-cell adhesions, and cytoskeletal reorganization. By binding integrin α5β1 on endothelia cells it inhibits the signaling pathways of Ras and
CPNE8 (538 words) [view diff] exact match in snippet view article find links to article
calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. GRCh38: Ensembl release 89: ENSG00000139117
CPNE4 (415 words) [view diff] exact match in snippet view article find links to article
calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. GRCh38: Ensembl release 89: ENSG00000196353
CRKL (3,098 words) [view diff] exact match in snippet view article find links to article
1997). "Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to
CLCA1 (1,005 words) [view diff] exact match in snippet view article find links to article
Elble RC, Pauli BU (2002). "Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth". J. Biol. Chem. 277
NCK2 (1,543 words) [view diff] exact match in snippet view article find links to article
"The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells". Molecular and Cellular
FLNB (1,335 words) [view diff] exact match in snippet view article find links to article
affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits". J. Cell Biol. United States. 156 (2): 361–76. doi:10
FHL3 (1,130 words) [view diff] exact match in snippet view article find links to article
FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor". J. Biol. Chem. 279 (27): 28641–52. doi:10.1074/jbc.M312894200
VNN2 (745 words) [view diff] exact match in snippet view article find links to article
a beta2 integrin associated glycosylphosphatidylinositol-anchored protein, concentrates on pseudopodia without association with beta2 integrin during neutrophil
CPNE1 (610 words) [view diff] exact match in snippet view article find links to article
calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein
TSPAN7 (943 words) [view diff] exact match in snippet view article find links to article
role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric
Protein kinase D1 (1,305 words) [view diff] exact match in snippet view article find links to article
vascular endothelial growth factor receptor signaling pathway • regulation of integrin-mediated signaling pathway • positive regulation of NF-kappaB transcription
Glycoprotein IIb/IIIa inhibitors (175 words) [view diff] exact match in snippet view article find links to article
associated with increased mortality and hence should not be given. In integrin nomenclature glycoprotein IIb/IIIa is called αIIbβ3. Their development
ST3GAL5 (824 words) [view diff] exact match in snippet view article find links to article
proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane
Pemphigoid (5,854 words) [view diff] exact match in snippet view article find links to article
scar in bullous pemphigoid. Antibodies to the beta-4 integrin subunit of alpha-6-beta-4 integrin is shown to be associated with ocular disease while oral
RRAS (1,142 words) [view diff] exact match in snippet view article find links to article
contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras". J. Biol. Chem. 275 (7): 5222–7. doi:10.1074/jbc.275
Abrilumab (67 words) [view diff] exact match in snippet view article find links to article
Abrilumab Monoclonal antibody Type ? Source Human Target integrin alpha-4 beta-7 Clinical data Other names AMG 181 ATC code none Identifiers CAS Number
Actinin alpha 2 (2,571 words) [view diff] exact match in snippet view article find links to article
Schöck F (December 2007). "Zasp is required for the assembly of functional integrin adhesion sites". The Journal of Cell Biology. 179 (7): 1583–97. doi:10
ICAM5 (845 words) [view diff] exact match in snippet view article find links to article
(telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18". Eur. J. Immunol. 30 (3): 810–8. doi:10
PAC-1 (1,828 words) [view diff] exact match in snippet view article find links to article
This article refers to the anti-tumor molecule, and not the a2iib3 integrin activation specific antibody of the same name PAC-1 (first procaspase activating
Laminin, beta 2 (1,362 words) [view diff] exact match in snippet view article find links to article
2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal
Max Planck Institute of Biochemistry (654 words) [view diff] exact match in snippet view article find links to article
Single-Molecule Imaging, Biophysics) Molecular Medicine (Reinhard Fässler / Integrin, Adhesion Signalling, Mouse Genetics) Cell Dynamics (Günther Gerisch /
RAP1B (980 words) [view diff] exact match in snippet view article find links to article
small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3". Blood. 107 (7): 2728–35. doi:10.1182/blood-2005-07-3023
FHL2 (5,021 words) [view diff] exact match in snippet view article find links to article
FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor". The Journal of Biological Chemistry. 279 (27): 28641–52. doi:10
CYTH1 (1,401 words) [view diff] exact match in snippet view article find links to article
natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. CYTH1 protein is 83% homologous
LYN (3,767 words) [view diff] exact match in snippet view article find links to article
in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells". The Journal of Biological Chemistry
Vitaxin (255 words) [view diff] exact match in snippet view article find links to article
Vitaxin (MEDI-523) is a humanized monoclonal antibody against the vascular integrin alpha-v beta-3. It is shown to be a promising angiogenesis inhibitor used
Calx-beta motif (190 words) [view diff] exact match in snippet view article find links to article
The calx-beta motif is also present in the cytoplasmic tail of mammalian integrin-beta4, which mediates the bi-directional transfer of signals across the
David Schlaepfer (629 words) [view diff] exact match in snippet view article find links to article
Schlaepfer, D.D., Hanks, S.K., Hunter, T., and van der Geer, P. (1994). Integrin-mediated signal transduction linked to Ras Pathway by Grb2 Binding to Focal
MMP1 (1,513 words) [view diff] exact match in snippet view article find links to article
Parks WC, Santoro SA (August 2001). "Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction". J
Collagen, type V, alpha 1 (1,067 words) [view diff] exact match in snippet view article find links to article
matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin". EMBO J. 17 (6): 1606–13. doi:10.1093/emboj/17
Thrombospondin 1 (2,104 words) [view diff] exact match in snippet view article find links to article
least 12 cell adhesion receptors, including CD36, αv integrins, β1 integrins, syndecan, and integrin-associated protein (IAP or CD47). It also interacts
Marginal zone B-cell (1,482 words) [view diff] exact match in snippet view article find links to article
these cells shear flow via the LFA-1 integrin ligand ICAM-1 and adhere or migrate down the flow via the VLA-4 integrin ligand VCAM-1. While CXCR5/CXCL13
FERMT2 (861 words) [view diff] exact match in snippet view article find links to article
shape change. A major task of kindlins is to regulate the activation of integrins. FERMT2 has been shown to interact with FBLIM1. Loss of kindlin-2 in mice
GPVI (1,419 words) [view diff] exact match in snippet view article find links to article
PMID 12649139. Watson SP, Auger JM, McCarty OJ, Pearce AC (Aug 2005). "GPVI and integrin alphaIIb beta3 signaling in platelets". Journal of Thrombosis and Haemostasis
PTPN11 (4,244 words) [view diff] exact match in snippet view article find links to article
platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling". J. Biol. Chem. 272 (11): 6986–93. doi:10
Mir-542 microRNA precursor family (716 words) [view diff] exact match in snippet view article find links to article
T, Aozasa K, Okada M (March 2012). "MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression". Oncogene. 31 (13):
AUP1 (567 words) [view diff] exact match in snippet view article find links to article
sequence of the cytoplasmic tail of integrin alpha (IIb) subunits. These subunits play a crucial role in the integrin alpha (IIb) beta (3) inside-out signalling
TGF beta 2 (890 words) [view diff] exact match in snippet view article find links to article
progesterone • cell death • cardioblast differentiation • positive regulation of integrin biosynthetic process • protein phosphorylation • positive regulation of
Anoikis (765 words) [view diff] exact match in snippet view article find links to article
develop anoikis resistance by several mechanisms, including changes in integrin and matrix signaling, metabolic deregulation, and stress responses of cancer
CX3CL1 (1,433 words) [view diff] exact match in snippet view article find links to article
binding • CCR chemokine receptor binding • signaling receptor binding • integrin binding • CX3C chemokine receptor binding Cellular component • integral
Von Willebrand factor (2,081 words) [view diff] exact match in snippet view article find links to article
type A domain) the C4 domain, in which the RGD motif binds to platelet integrin αIIbβ3 when this is activated (von Willebrand factor type C domain) the
SH2D3C (976 words) [view diff] exact match in snippet view article find links to article
important regulator of lymphocyte adhesion, acting upstream of Rap1 in the integrin activation pathway. GRCh38: Ensembl release 89: ENSG00000095370 - Ensembl
ANGPTL3 (1,194 words) [view diff] exact match in snippet view article find links to article
domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This
EMP2 (696 words) [view diff] exact match in snippet view article find links to article
"Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium". Dev Biol. 287 (2): 336–45. doi:10.1016/j.ydbio.2005
EDIL3 (591 words) [view diff] exact match in snippet view article find links to article
humans is encoded by the EDIL3 gene. The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be
KIF14 (577 words) [view diff] exact match in snippet view article find links to article
• cytosol • Flemming body Biological process • negative regulation of integrin activation • cerebral cortex development • negative regulation of apoptotic
PAK4 (3,062 words) [view diff] exact match in snippet view article find links to article
though phosphorylation of its effector proteins, including, LIMK1-Thr508, integrin β5-Ser759/Ser762, p120-catenin-Ser288, superior cervical ganglia 10 (SCG10)-Ser50
ITGB1BP3 (452 words) [view diff] exact match in snippet view article find links to article
Medicine. Li J, Mayne R, Wu C (Feb 2000). "A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation". J Cell
CCL21 (1,328 words) [view diff] exact match in snippet view article find links to article
Zuzel M, Cawley JC (April 2002). "The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into
CSPG4 (1,488 words) [view diff] exact match in snippet view article find links to article
role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion". The Journal of Biological Chemistry.
KRIT1 (1,389 words) [view diff] exact match in snippet view article find links to article
2001). "Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation"
Uterine natural killer cells (1,044 words) [view diff] exact match in snippet view article find links to article
unique expression profile of certain proteins, specifically CD9, CD103 (an integrin) and killer immunoglobulin-like receptors (KIRs). Notably, mouse models
Laminin, beta 1 (1,251 words) [view diff] exact match in snippet view article find links to article
Leivo I, Franssila K, Virtanen I (1997). "Changes in the distribution of integrins and their basement membrane ligands during development of human thyroid
Syndecan-4 (2,087 words) [view diff] exact match in snippet view article find links to article
cytoskeletal and signaling proteins inside the cell to modulate the function of integrin in cell-matrix adhesion. Also, syndecans bind to FGFs and bring them to
Polycomb protein EED (1,317 words) [view diff] exact match in snippet view article find links to article
This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase
NME2 (1,235 words) [view diff] exact match in snippet view article find links to article
Dupé-Manet S, Bouvard D, Lacombe ML, Marie C, Block MR, Albiges-Rizo C (2002). "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly
CBL (gene) (3,758 words) [view diff] exact match in snippet view article
Golemis EA, Griffin JD (May 1997). "Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1)"
DAB2 (1,385 words) [view diff] exact match in snippet view article find links to article
(2003). "Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling"
Calnexin (2,168 words) [view diff] exact match in snippet view article find links to article
Vestweber D (Apr 1994). "The integrin chains beta 1 and alpha 6 associate with the chaperone calnexin prior to integrin assembly". The Journal of Biological
Congenital muscular dystrophy (2,040 words) [view diff] exact match in snippet view article find links to article
creatine kinase. Individual may show a diaphragmatic manner when breathing. Integrin α7 weakness which is present at birth, poor muscle tone with late walking
NEU3 (1,111 words) [view diff] exact match in snippet view article find links to article
"Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling"
NCK1 (3,425 words) [view diff] exact match in snippet view article find links to article
105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes". J. Exp. Med. 184 (4): 1365–75. doi:10
Erbin (protein) (1,517 words) [view diff] exact match in snippet view article
2001). "The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative
Horst Kessler (730 words) [view diff] exact match in snippet view article find links to article
Kantlehner; Horst Kessler; Joachim P Spatz (1 March 2004). "Activation of integrin function by nanopatterned adhesive interfaces". ChemPhysChem. 5 (3): 383–388
FBLN1 (1,653 words) [view diff] exact match in snippet view article find links to article
binding • extracellular matrix structural constituent • fibrinogen binding • integrin binding • protein C-terminus binding • GO:0001948 protein binding • identical
PRAM1 (694 words) [view diff] exact match in snippet view article find links to article
Koretzky GA, Peterson EJ (Dec 2004). "PRAM-1 Is Required for Optimal Integrin-Dependent Neutrophil Function". Mol Cell Biol. 24 (24): 10923–32. doi:10
PARVA (671 words) [view diff] exact match in snippet view article find links to article
Zhang Y, et al. (2001). "A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading". J. Cell Biol
Proto-oncogene tyrosine-protein kinase Src (2,781 words) [view diff] exact match in snippet view article find links to article
transferase activity • ephrin receptor binding • scaffold protein binding • integrin binding • GO:0001948 protein binding • protein kinase binding • cell adhesion
SH2D3A (544 words) [view diff] exact match in snippet view article find links to article
TA (Apr 1999). "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated
Mir-30 microRNA precursor (584 words) [view diff] exact match in snippet view article find links to article
found to be highly expressed in heart cells. It has been shown that the integrin ITGB3 and the ubiquitin conjugating E2 enzyme UBC9 are downregulated by
RTX toxin (2,523 words) [view diff] exact match in snippet view article find links to article
these cells). These toxins recognize protein receptors such as the β2-integrins, form pores at high concentrations, and cause cell rupture by mechanisms
FUT8 (996 words) [view diff] exact match in snippet view article find links to article
process • protein glycosylation in Golgi • regulation of gene expression • integrin-mediated signaling pathway • protein N-linked glycosylation • transforming
Mark Yeager (76 words) [view diff] exact match in snippet view article find links to article
American biologist, focusing in cardiac gap junction membrane channels, integrin water channels, rotavirus, reovirus and retrovirus. Yeager is a professor
Otilimab (718 words) [view diff] exact match in snippet view article find links to article
antibodies used in the treatment of multiple sclerosis: natalizumab (targets α4-integrin), daclizumab and alemtuzumab (both binding to CD25, the α-subunit of IL-2
Secretome (780 words) [view diff] exact match in snippet view article find links to article
Iyengar, Ravi; Geiger, Benjamin (August 2007). "Functional atlas of the integrin adhesome". Nature Cell Biology. 9 (8): 858–867. doi:10.1038/ncb0807-858
MMP14 (407 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • zinc ion binding • metal ion binding • integrin binding • peptidase activity • GO:0001948 protein binding • metalloendopeptidase
GIPC1 (1,891 words) [view diff] exact match in snippet view article find links to article
PMID 12724327. Tani TT, Mercurio AM (September 2001). "PDZ interaction sites in integrin alpha subunits. T14853, TIP/GIPC binds to a type I recognition sequence
Secretome (780 words) [view diff] exact match in snippet view article find links to article
Iyengar, Ravi; Geiger, Benjamin (August 2007). "Functional atlas of the integrin adhesome". Nature Cell Biology. 9 (8): 858–867. doi:10.1038/ncb0807-858
GIPC1 (1,891 words) [view diff] exact match in snippet view article find links to article
PMID 12724327. Tani TT, Mercurio AM (September 2001). "PDZ interaction sites in integrin alpha subunits. T14853, TIP/GIPC binds to a type I recognition sequence
GPR124 (719 words) [view diff] exact match in snippet view article find links to article
(TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans". J. Biol. Chem. 281 (45): 34179–88
Titanium biocompatibility (1,630 words) [view diff] exact match in snippet view article find links to article
to enhance integrin binding and signaling and stem cell differentiation. Increasing the density of ligand clustering also increased integrin binding. A
GSG2 (389 words) [view diff] exact match in snippet view article find links to article
"The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid
Francevillian biota (750 words) [view diff] exact match in snippet view article find links to article
Lang, F. B.; King, N.; Ruiz-Trillo, I. (2010). "Ancient origin of the integrin-mediated adhesion and signaling machinery". Proceedings of the National
Sarcospan (429 words) [view diff] exact match in snippet view article find links to article
complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin". Human Molecular Genetics. 24 (7): 2011–22. doi:10.1093/hmg/ddu615. PMC 4355028
HMGB1 (3,077 words) [view diff] exact match in snippet view article find links to article
kinase activator activity • GO:0001105 transcription coactivator activity • integrin binding Cellular component • cytoplasm • endosome • membrane • transcription
MGAT5B (918 words) [view diff] exact match in snippet view article find links to article
hdl:1874/5091. PMID 11530211. Abbott KL, Troupe K, Lee I, Pierce M (2006). "Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated
EIF2A (992 words) [view diff] exact match in snippet view article find links to article
(Jun 2005). "Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways". Proceedings
Matrix (biology) (646 words) [view diff] exact match in snippet view article
bind to cell surface receptor proteins called integrins that are built into the plasma membrane. Integrins span the membrane and bind on the cytoplasmic
Collagen, type VIII, alpha 2 (795 words) [view diff] exact match in snippet view article find links to article
endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study". Circulation. 114 (8):
Dally (gene) (825 words) [view diff] exact match in snippet view article
are Bone Morphogenetic Proteins, and the mammalian equal to Wg might be integrin-beta 4. The first one (Wg) controls cell proliferation and differentiation
S1PR3 (889 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function • signal transducer activity • lipid binding • integrin binding • sphingosine-1-phosphate receptor activity • G protein-coupled
DOK1 (1,374 words) [view diff] exact match in snippet view article find links to article
Clemmons DR (February 2005). "DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured
Aggregatibacter actinomycetemcomitans (905 words) [view diff] exact match in snippet view article find links to article
kills granulocytes, monocytes, and other white blood cells expressing integrin beta-2 (CD18) Cytolethal distending toxin Immunosuppression factors that
Tumstatin (1,490 words) [view diff] exact match in snippet view article find links to article
alpha chain on the collagen strand. Tumstatin interacts with the αvβ3 integrin found in the apoptosis pathway. There are two activation sites on the tumstatin
Collagen, type III, alpha 1 (3,414 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • metal ion binding • integrin binding • GO:0001948 protein binding • platelet-derived growth factor binding • SMAD binding
Papillomaviridae (7,083 words) [view diff] exact match in snippet view article find links to article
via interaction with a specific receptor, likely via the alpha-6 beta-4 integrin, and transported to membrane-enclosed vesicles called endosomes. The capsid
BCAR3 (930 words) [view diff] exact match in snippet view article find links to article
Stewart TA (1999). "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated
DOK1 (1,374 words) [view diff] exact match in snippet view article find links to article
Clemmons DR (February 2005). "DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured
Adapter molecule crk (2,930 words) [view diff] exact match in snippet view article find links to article
Sekiguchi K (2001). "Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathway".
Fatshark (772 words) [view diff] exact match in snippet view article find links to article
"Flatshark reste sig ur ruinerna av Grin" [Fatshark rose from the ruin of Integrin] (in Swedish). IDG.se. Retrieved 10 September 2012. "Fatshark profile page"
LPXN (643 words) [view diff] exact match in snippet view article find links to article
Woodside DG, et al. (2000). "Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses". Nature. 402 (6762): 676–81.
MZB1 (559 words) [view diff] exact match in snippet view article find links to article
"Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells". Immunity. 33 (5): 723–35. doi:10.1016/j
PTPRM (6,046 words) [view diff] exact match in snippet view article find links to article
interaction between PTPmu and catenins is only indirect through E-cadherin. α3β1 integrin and the tetraspanin CD151 regulate PTPmu gene expression to promote E-cadherin-mediated
Yu-Shan Lin (chemist) (1,105 words) [view diff] exact match in snippet view article
(September 2, 2016). "Mapping the Effect of Gly Mutations in Collagen on α2β1 Integrin Binding *". Journal of Biological Chemistry. 291 (36): 19196–19207. doi:10
Cancer cell (1,586 words) [view diff] exact match in snippet view article find links to article
Shumei Kato, Aleksandra Franovic, et al., & David A. Cheresh (2014). An integrin β3–KRAS–RalB complex drives tumour stemness and resistance to EGFR inhibition
GNAI1 (1,442 words) [view diff] exact match in snippet view article find links to article
PMID 10978845. S2CID 21002590. Brown EJ, Frazier WA (Mar 2001). "Integrin-associated protein (CD47) and its ligands". Trends in Cell Biology. 11
TXK (gene) (715 words) [view diff] exact match in snippet view article
cell population proliferation • peptidyl-tyrosine autophosphorylation • integrin-mediated signaling pathway • protein autophosphorylation • regulation of
CAPN1 (1,047 words) [view diff] exact match in snippet view article find links to article
Ginsberg MH (1995). "Calpain cleavage of the cytoplasmic domain of the integrin beta 3 subunit". J. Biol. Chem. 270 (44): 26146–51. doi:10.1074/jbc.270
Stromal cell-derived factor 1 (2,773 words) [view diff] exact match in snippet view article find links to article
chemoattractant activity • growth factor activity • signaling receptor binding • integrin binding • GO:0001948 protein binding Cellular component • plasma membrane
NME1 (1,379 words) [view diff] exact match in snippet view article find links to article
Bouvard D, Lacombe ML, Marie C, Block MR, Albiges-Rizo C (June 2002). "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly
List of target antigens in pemphigoid (190 words) [view diff] exact match in snippet view article find links to article
Cicatricial pemphigoid C-terminal of BPAG2 180 Ocular cicatricial pemphigoid Integrin beta-4 subunit 200 Antiepiligrin cicatricial pemphigoid Laminin 5 (Epiligrin
LCP1 (1,046 words) [view diff] exact match in snippet view article find links to article
PMID 9923600. Wang J, Brown EJ (August 1999). "Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A". The
Lee Byung-heon (biochemist) (2,891 words) [view diff] exact match in snippet view article
VEGF165-Induced Angiogenesis by Targeting the Interaction between VEGFR-2 and v 3 Integrin". Molecular Cancer Research. 10 (8): 1010–1020. doi:10.1158/1541-7786.MCR-11-0600
Annexin A5 (1,634 words) [view diff] exact match in snippet view article find links to article
Annexin A5 has been shown to interact with Kinase insert domain receptor and Integrin, beta 5. GRCh38: Ensembl release 89: ENSG00000164111 - Ensembl, May 2017
Lipid raft (6,373 words) [view diff] exact match in snippet view article find links to article
lipid rafts in non-coated vesicles. EV1 uses α2β1-integrin as cellular receptor. Multiple integrin heterodimers can bind to the adjacent sites of the
Stromal cell-derived factor 1 (2,773 words) [view diff] exact match in snippet view article find links to article
chemoattractant activity • growth factor activity • signaling receptor binding • integrin binding • GO:0001948 protein binding Cellular component • plasma membrane
PIEZO1 (936 words) [view diff] exact match in snippet view article find links to article
regulation of cell-cell adhesion mediated by integrin • cation transport • positive regulation of integrin activation • ion transport • cation transmembrane
Autotaxin (1,930 words) [view diff] exact match in snippet view article find links to article
Perrakis A (February 2011). "Structural basis of substrate discrimination and integrin binding by autotaxin". Nature Structural & Molecular Biology. 18 (2): 198–204
JAM3 (1,132 words) [view diff] exact match in snippet view article find links to article
molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1". J. Exp. Med. 196 (5): 679–91. doi:10.1084/jem.20020267. PMC 2194005
KLF10 (1,053 words) [view diff] exact match in snippet view article find links to article
beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter". J. Biol. Chem. 279 (26): 26948–58. doi:10.1074/jbc.M310634200
Safrole (3,331 words) [view diff] exact match in snippet view article find links to article
on the central nervous system. Safrole oxide inhibits the expression of integrin β4/SOD, which leads to apoptosis of the nerve cells. Safrole is listed
S1PR2 (1,111 words) [view diff] exact match in snippet view article find links to article
protein-coupled receptor binding • G protein-coupled receptor activity • integrin binding • GO:0001948 protein binding • sphingosine-1-phosphate receptor
NBR1 (864 words) [view diff] exact match in snippet view article find links to article
with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in
HOXD3 (962 words) [view diff] exact match in snippet view article find links to article
Varner JA (Feb 2004). "The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis". The Journal of
Whipple's disease (1,530 words) [view diff] exact match in snippet view article find links to article
disease. In particular, circulating cells which are CD11b (also known as integrin alpha) expressive are reduced in susceptible individuals. CD11b has a vital
ZNF148 (1,027 words) [view diff] exact match in snippet view article find links to article
finger transcription factor ZBP-89 is a repressor of the human beta 2-integrin CD11b gene". Blood. 101 (3): 894–902. doi:10.1182/blood-2002-03-0680. PMID 12393719
ESM1 (706 words) [view diff] exact match in snippet view article find links to article
(2001). "Human endothelial-cell specific molecule-1 binds directly to the integrin CD11a/CD18 (LFA-1) and blocks binding to intercellular adhesion molecule-1"
Hemicentin 1 (638 words) [view diff] exact match in snippet view article find links to article
Whittaker CA, Hynes RO (2003). "Distribution and Evolution of von Willebrand/Integrin A Domains: Widely Dispersed Domains with Roles in Cell Adhesion and Elsewhere"
Hemicentin 1 (638 words) [view diff] exact match in snippet view article find links to article
Whittaker CA, Hynes RO (2003). "Distribution and Evolution of von Willebrand/Integrin A Domains: Widely Dispersed Domains with Roles in Cell Adhesion and Elsewhere"
Glycoprotein (1,577 words) [view diff] exact match in snippet view article find links to article
(luteinizing hormone a follicle-stimulating hormone) glycoprotein IIb/IIIa, an integrin found on platelets that is required for normal platelet aggregation and
RAP1GAP (992 words) [view diff] exact match in snippet view article find links to article
Murata N, Harazaki M, Kaibuchi K, Minato N (April 2003). "AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific
Alpha-1B adrenergic receptor (1,241 words) [view diff] exact match in snippet view article find links to article
2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits". J. Biol. Chem. 279 (35): 36593–600. doi:10.1074/jbc.M402084200
Myofibroblast (1,065 words) [view diff] exact match in snippet view article find links to article
intracellular contraction and concomitant alignment of the collagen fibers by integrin-mediated pulling on to the collagen bundles. Pericytes and renal mesangial
Convergent extension (795 words) [view diff] exact match in snippet view article find links to article
certain cell-cell adhesion molecules, such as C-cadherin and fibronectin/integrin interactions, may also play a role. Reduction of the activity of these
Cardiomyoplasty (1,262 words) [view diff] exact match in snippet view article find links to article
purified natural biopolymers or by coupling the synthetic component with integrin and/or growth factor binding sites. Cardiomyoplasty. Carpentier, Alain
IAP (438 words) [view diff] exact match in snippet view article find links to article
suppression of programmed cell death (apoptosis) Integrated automation platform Integrin Associated Protein or CD47 protein Internet access provider, also known
Nephronectin (345 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • calcium ion binding • integrin binding • extracellular matrix structural constituent Cellular component • membrane •
PLK3 (1,197 words) [view diff] exact match in snippet view article find links to article
"The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity"
DAPK1 (1,168 words) [view diff] exact match in snippet view article find links to article
Yao CC, Chen RH (Oct 2002). "DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals". The Journal of Cell Biology
REV1 (1,092 words) [view diff] exact match in snippet view article find links to article
interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains". FEBS Lett. 445 (2–3): 351–5. doi:10.1016/S0014-5793(99)00151-9
CCL22 (1,116 words) [view diff] exact match in snippet view article find links to article
"Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion". J. Immunol. 169 (5): 2303–12. doi:10.4049/jimmunol
ZBTB17 (1,204 words) [view diff] exact match in snippet view article find links to article
Viklund EK, Strömblad S (Sep 2002). "P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration". The
PTP4A3 (936 words) [view diff] exact match in snippet view article find links to article
PMID 16203771. Peng L, Jin G, Wang L, et al. (2006). "Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3"
Epiblast (1,190 words) [view diff] exact match in snippet view article find links to article
Polarization results from the interaction between the mammalian blastocyst and β1-integrin from the extracellular matrix, produced from the extra-embryonic tissues
ABL (gene) (3,460 words) [view diff] exact match in snippet view article
105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes". J. Exp. Med. 184 (4): 1365–75. doi:10
PTPRZ1 (1,146 words) [view diff] exact match in snippet view article find links to article
receptor protein tyrosine phosphatase activity • hydrolase activity • integrin binding Cellular component • integral component of membrane • membrane
CCL28 (707 words) [view diff] exact match in snippet view article find links to article
Paquet AC, Yang YH, Erle DJ (July 2004). "Differential gene expression by integrin beta 7+ and beta 7- memory T helper cells". BMC Immunology. 5: 13. doi:10
PTPRA (1,270 words) [view diff] exact match in snippet view article find links to article
activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced
Actinin alpha 1 (1,326 words) [view diff] exact match in snippet view article find links to article
1007/BF02818986. PMID 8997639. Menko S, Philp N, Veneziale B, Walker J (1998). "Integrins and development: how might these receptors regulate differentiation of