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searching for Immunoglobulin heavy chain 44 found (70 total)

alternate case: immunoglobulin heavy chain

IGHV@ (602 words) [view diff] exact match in snippet view article find links to article

protein that in humans is encoded by the IGHV@ gene. IGHV is the immunoglobulin heavy chain variable region genes; in B-cell neoplasms like chronic lymphocytic
Locus suicide recombination (165 words) [view diff] exact match in snippet view article find links to article
variant form of class switch recombination that eliminates all immunoglobulin heavy chain constant genes. It thus terminates immunoglobulin and B-cell receptor
Intraocular lymphoma (713 words) [view diff] exact match in snippet view article find links to article
(PCR) amplification to identify monoclonal rearrangements of the immunoglobulin heavy chain (IgH) gene (for B-cell lymphomas) or T-cell receptor (TCR, for
CRLF2 (590 words) [view diff] exact match in snippet view article find links to article
of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) (chromosome 14), or with P2Y purinoceptor 8 gene (P2RY8)
T. J. Hamblin (449 words) [view diff] exact match in snippet view article find links to article
lymphocytic leukaemia comes in two forms, depending on whether the immunoglobulin heavy chain variable region genes contain somatic mutations. If they do the
Suzanne Eaton (1,154 words) [view diff] exact match in snippet view article find links to article
Angeles in 1988. Her thesis, entitled Molecular analysis of an immunoglobulin heavy chain promoter, was completed under the supervision of Kathryn Calame
ARID3A (906 words) [view diff] no match in snippet view article find links to article
Ayers N, Desgranges ZP, Roy AL, Webb CF (Jun 2006). "Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires
CD79A (2,419 words) [view diff] exact match in snippet view article find links to article
function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with
TFE3 (1,350 words) [view diff] no match in snippet view article find links to article
family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al.
IGHA2 (604 words) [view diff] exact match in snippet view article find links to article
PMID 6804948. Flanagan JG, Rabbitts TH (Dec 1982). "Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment
Receptor editing (280 words) [view diff] no match in snippet view article find links to article
RR, Tarlinton, D (1986). 'Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly1+ B-cell lymphoma'
IGHD (793 words) [view diff] no match in snippet view article find links to article
Gaëta B, Malming HR, et al. (2006). "Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire"
MYC (625 words) [view diff] exact match in snippet view article find links to article
site is required for the deregulation of c-myc expression by the immunoglobulin heavy chain gene enhancers in Burkitt's lymphoma". J. Biol. Chem. 277 (12):
IL1RAPL2 (504 words) [view diff] exact match in snippet view article find links to article
translocation of variable and diversity segments of the human immunoglobulin heavy chain from chromosome 14 to chromosomes 15 and 16". Genomics. 22 (1):
DNAJC3 (1,471 words) [view diff] no match in snippet view article find links to article
are still only partly known. It was shown that loss of the BiP (immunoglobulin heavy-chain binding protein) co-chaperone DNAJC3 leads to diabetes mellitus
HOXC4 (1,162 words) [view diff] exact match in snippet view article find links to article
(2004). "The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch
Tasuku Honjo (1,476 words) [view diff] exact match in snippet view article find links to article
"Organization of the constant-region gene family of the mouse immunoglobulin heavy chain". Cell. Elsevier BV. 28 (3): 499–506. doi:10.1016/0092-8674(82)90204-5
Michael Neuberger (724 words) [view diff] exact match in snippet view article find links to article
in Suffolk." Neuberger MS (1983) Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells. EMBO J 2: 1373–1378 Neuberger
ARID domain (609 words) [view diff] no match in snippet view article find links to article
Kaplan MH, Lelsz DL, Das C, Scheuermann R, Tucker PW (1995). "The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific
MLIP (gene) (792 words) [view diff] exact match in snippet view article
Stein H, Versmold HT (March 2001). "The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants
ATF6 (1,281 words) [view diff] no match in snippet view article find links to article
pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription
Laser capture microdissection (1,741 words) [view diff] exact match in snippet view article find links to article
capture microdissection to cytologic specimens for the detection of immunoglobulin heavy chain gene rearrangement in patients with malignant lymphoma". Cancer
Somatic hypermutation (2,334 words) [view diff] exact match in snippet view article find links to article
overview of V(D)J recombination and somatic hypermutations at the immunoglobulin heavy chain variable region. Abbreviation of the regions: C = constant, D
Thyroglobulin (1,979 words) [view diff] exact match in snippet view article find links to article
of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein". J. Biol. Chem. 276 (24): 21337–42. doi:10.1074/jbc
YY1 (1,917 words) [view diff] no match in snippet view article find links to article
delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site". Proceedings of the National Academy of Sciences of
Susumu Tonegawa (1,614 words) [view diff] exact match in snippet view article find links to article
enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell, 33(3), 717-728. Mombaerts, P., Iacomini, J., Johnson
J. Donald Capra (1,683 words) [view diff] no match in snippet view article find links to article
PMC 54020. PMID 2111022. Pascual, V.; Capra, J. D. (1991). Human immunoglobulin heavy-chain variable region genes: Organization, polymorphism, and expression
E-box (3,720 words) [view diff] no match in snippet view article find links to article
Walter Gilbert's laboratories in 1985 as a control element in immunoglobulin heavy-chain enhancer. They found that a region of 140 base pairs in the tissue-specific
John S. K. Kauwe III (1,836 words) [view diff] case mismatch in snippet view article find links to article
Marijon; X, Jouven (2017-05-11). "Association Between a Common Immunoglobulin Heavy Chain Allele and Rheumatic Heart Disease Risk in Oceania". Nature Communications
Adenylylation (3,241 words) [view diff] no match in snippet view article find links to article
Hendershot LM, Ting J, Lee AS (October 1988). "Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein
Allelic exclusion (1,984 words) [view diff] case mismatch in snippet view article find links to article
Biomedical Literature (Report). doi:10.3410/f.1002314.23155. "Immunoglobulin Heavy Chain Variable, Diversity, and Joining Region Gene Rearrangement". National
Bcl-2 (4,655 words) [view diff] exact match in snippet view article find links to article
– which places the Bcl-2 gene from chromosome 18 next to the immunoglobulin heavy chain locus on chromosome 14. This fusion gene is deregulated, leading
DNA polymerase beta (2,435 words) [view diff] exact match in snippet view article find links to article
gland morphogenesis cellular response to DNA damage stimulus immunoglobulin heavy chain V-D-J recombination DNA replication somatic diversification of
DNA polymerase beta (2,435 words) [view diff] exact match in snippet view article find links to article
gland morphogenesis cellular response to DNA damage stimulus immunoglobulin heavy chain V-D-J recombination DNA replication somatic diversification of
Binding immunoglobulin protein (3,623 words) [view diff] exact match in snippet view article find links to article
(GRPs), is markedly increased. GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70
List of MeSH codes (G14) (3,088 words) [view diff] exact match in snippet view article
– genes, immunoglobulin MeSH G14.340.024.340.351.300 – genes, immunoglobulin heavy chain MeSH G14.340.024.340.351.300.249 – hinge exons MeSH G14.340.024
Thomas Jenuwein (2,071 words) [view diff] exact match in snippet view article find links to article
Heidelberg and performed postdoctoral studies (1987-1993) on the immunoglobulin heavy chain (IgH) enhancer with Rudolf Grosschedl at the University of California
Serum free light-chain measurement (3,336 words) [view diff] no match in snippet view article find links to article
approximately 40% excess immunoglobulin light-chain production over immunoglobulin heavy-chain synthesis. Possibly this is simply to allow proper conformation
Eosinophilia (5,480 words) [view diff] no match in snippet view article find links to article
leukemia resulted in the juxtaposition of the IL-3 gene and the immunoglobulin heavy-chain gene, causing overproduction production of IL-3, leading to blood
Follicular lymphoma (7,912 words) [view diff] exact match in snippet view article find links to article
2 (BCL2) gene on chromosome 18 at position q21.33 near to the immunoglobulin heavy chain locus (IGH@) on chromosome 14 at position q21. In consequence
Small Maf (3,041 words) [view diff] exact match in snippet view article find links to article
B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer". EMBO J. 17 (19): 5734–43. doi:10.1093/emboj/17
In situ lymphoid neoplasia (2,696 words) [view diff] exact match in snippet view article find links to article
lymphoma 2 (BCL2) gene on chromosome 18 at position q21.33 with the immunoglobulin heavy chain locus (IGH@) on chromosome 14 at position q21. In consequence
Split gene theory (8,021 words) [view diff] exact match in snippet view article find links to article
enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene". Cell. 33 (3): 717–728. doi:10.1016/0092-8674(83)90014-4
G-quadruplex (11,501 words) [view diff] exact match in snippet view article find links to article
has been suggested that quadruplex formation plays a role in immunoglobulin heavy chain switching. As cells have evolved mechanisms for resolving (i.e