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searching for Heat shock response 51 found (63 total)

Hsp90 cis-regulatory element (126 words) [view diff] exact match in snippet view article find links to article

translational efficiency during the heat shock response. The hsp90 gene product is involved in the Drosophila heat shock response. Translation of the hsp90 mRNA

HSF4 (741 words) [view diff] no match in snippet view article find links to article

the HSF4 gene. Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the

Heat shock protein (5,533 words) [view diff] exact match in snippet view article find links to article

dramatic upregulation of the heat shock proteins is a key part of the heat shock response and is induced primarily by heat shock factor (HSF). HSPs are found

Heat shock factor protein 1 (2,454 words) [view diff] exact match in snippet view article find links to article

Hsp70 negatively regulates HSF1. The HSF1 protein regulates the heat shock response (HSR) pathway in humans by acting as the major transcription factor

Bip internal ribosome entry site (IRES) (117 words) [view diff] exact match in snippet view article

protein expression has been found to be significantly enhanced by the heat shock response due to internal ribosome entry site (IRES)-dependent translation

Proteostasis (2,922 words) [view diff] exact match in snippet view article find links to article

theoretical mechanism for this approach includes upregulating the heat shock response response to rescue proteins from degradation during cellular stress

Herschel K. Mitchell (772 words) [view diff] exact match in snippet view article find links to article

(fruit flies), in particular the genetics and biochemistry of the heat shock response. Mitchell was born on November 27, 1913, in Los Nietos, California

Lon protease family (397 words) [view diff] exact match in snippet view article find links to article

after thermal stress, suggesting that PIM1 may play a role in the heat shock response. Lon proteases have two specific subfamilies: LonA and LonB, differentiated

Arimoclomol (841 words) [view diff] exact match in snippet view article find links to article

could treat a broad range of diseases. Arimoclomol activates the heat shock response. It is believed to act at Hsp70. Arimoclomol has been shown to extend

Andrew Dillin (102 words) [view diff] exact match in snippet view article find links to article

looks at the manipulation of stress response pathways, such as the heat shock response and the unfolded protein response of the mitochondria and the endoplasmic

Celastrol (1,174 words) [view diff] exact match in snippet view article find links to article

of proteasome function and activation of HSF1, which triggers the heat shock response. The available evidence indicates that celastrol bonds covalently

Arsenic poisoning (9,491 words) [view diff] exact match in snippet view article find links to article

1 mg/kg/day. Another aspect is the similarity of arsenic effects to the heat shock response. Short-term arsenic exposure has effects on signal transduction inducing

Cellular stress response (1,323 words) [view diff] exact match in snippet view article find links to article

artificially injected into it, it will trigger a stress response. The heat shock response involves a class of stress proteins called heat shock proteins. These

Hsp70 (5,687 words) [view diff] case mismatch in snippet view article find links to article

transcription of an unknown protein. This was later described as the "Heat Shock Response" and the proteins were termed the "Heat Shock Proteins" (Hsps). The

Eukaryotic translation elongation factor 1 alpha 1 (2,672 words) [view diff] exact match in snippet view article find links to article

interactions with mineralocorticoid receptors in the heart. Its role in heat shock response presents it as a target for treating related diseases like spinal

Importin α (1,829 words) [view diff] exact match in snippet view article find links to article

be mediated by importin αs including gametogenesis, development, heat shock response, protein degradation, and viral pathogen infection. Gametogenesis

Heat shock factor (743 words) [view diff] exact match in snippet view article find links to article

Cold-shock domain Sorger PK (May 1991). "Heat shock factor and the heat shock response". Cell. 65 (3): 363–6. doi:10.1016/0092-8674(91)90452-5. PMID 2018972

Regulon (647 words) [view diff] exact match in snippet view article find links to article

are those involved in response to stress such as heat shock. The heat shock response in E. coli is regulated by the sigma factor σ32 (RpoH), whose regulon

FourU thermometer (1,229 words) [view diff] exact match in snippet view article find links to article

of hairpin II from closed to open may have an important role in heat shock response. A later study used mutant analysis and calculations of enthalpy

HSF2 (973 words) [view diff] no match in snippet view article find links to article

HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Although the names

HSP90AB1 (3,113 words) [view diff] no match in snippet view article find links to article

B member 1". Retrieved 2019-08-30. Lindquist S (June 1986). "The heat-shock response". Annual Review of Biochemistry. 55 (1): 1151–1191. doi:10.1146/annurev

Zinc pyrithione (1,348 words) [view diff] exact match in snippet view article find links to article

Wondrak GT (May 2010). "The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in

TCIM (582 words) [view diff] exact match in snippet view article find links to article

2007). "TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response". Biochemical and Biophysical Research Communications. 360 (2): 447–52

RGS3 (1,052 words) [view diff] exact match in snippet view article find links to article

Iida J, Hata Y (2003). "C2PA is a nuclear protein implicated in the heat shock response". J. Cell. Biochem. 87 (1): 65–74. doi:10.1002/jcb.10279. PMID 12210723

Emerald rockcod (688 words) [view diff] exact match in snippet view article find links to article

Unlike most organisms, the emerald rockcod does not show a typical heat shock response; for example, it does not upregulate the heat shock protein gene

Susan Lindquist (2,779 words) [view diff] no match in snippet view article find links to article

1242/dmm.000810. PMC 2561974. PMID 19048046. Lindquist, S. (1986). "The Heat-Shock Response". Annual Review of Biochemistry. 55: 1151–91. doi:10.1146/annurev

Oxidation response (1,160 words) [view diff] exact match in snippet view article find links to article

between oxidative stress response and other regulatory networks like heat shock response, SOS response. The defenses against deleterious effects of active

Clusterin (2,433 words) [view diff] no match in snippet view article find links to article

heat-shock protein 90 (HSP90) inhibitor activity by suppressing the heat-shock response in castrate-resistant prostate cancer, and was tested in phase III

Inclusion bodies (2,583 words) [view diff] exact match in snippet view article find links to article

A, Goffin L, Georgopoulos C (August 1995). "The Escherichia coli heat shock response and bacteriophage lambda development". FEMS Microbiology Reviews

Zinc (16,224 words) [view diff] exact match in snippet view article find links to article

suggests that the topical antimicrobial zinc pyrithione is a potent heat shock response inducer that may impair genomic integrity with induction of PARP-dependent

VapBC (1,268 words) [view diff] exact match in snippet view article find links to article

solfataricus, for example, a vapBC gene cassette is thought to regulate heat shock response. Toxin-antitoxin database Robson, Jennifer; McKenzie, Joanna L.;

Transcription factory (1,688 words) [view diff] no match in snippet view article find links to article

1065–1071. doi:10.1038/ng1423. PMID 15361872. Lindquist S (1986). "The heat-shock response". Annu. Rev. Biochem. 55: 1151–1191. doi:10.1146/annurev.bi.55.070186

Tissue transglutaminase (3,913 words) [view diff] no match in snippet view article find links to article

Raia V, Maiuri L, Piacentini M (July 2018). "TG2 regulates the heat-shock response by the post-translational modification of HSF1". EMBO Reports. 19

Glutathione S-transferase (4,286 words) [view diff] exact match in snippet view article find links to article

the absence of oxidative stress, although ASK1 is also involved in heat shock response, which is likewise prevented during ASK1 sequestration. The fact

Cryopreservation (6,375 words) [view diff] no match in snippet view article find links to article

cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing". Cytotherapy. 14 (2): 147–52

Mitali Mukerji (2,873 words) [view diff] exact match in snippet view article find links to article

continued to work in trying to understand the mechanisms behind heat shock response systems and the functions of satellite non-coding RNA as a transcriptional

Transcription factor (8,057 words) [view diff] exact match in snippet view article find links to article

Shamovsky I, Nudler E (March 2008). "New insights into the mechanism of heat shock response activation". Cellular and Molecular Life Sciences. 65 (6): 855–61

Hana El-Samad (1,018 words) [view diff] exact match in snippet view article find links to article

Biological design principles for robustness, performance and selective interactions with noise : he E. coli heat shock response and other case studies. (2004)

Heavy water (9,923 words) [view diff] no match in snippet view article find links to article

concentrations of heavy water. In addition, the cells activated the heat-shock response pathway and the cell integrity pathway, and mutants in the cell integrity

Experimental cancer treatment (4,350 words) [view diff] exact match in snippet view article find links to article

death by apoptosis. There are many biochemical consequences to the heat shock response within the cell, including slowed cell division and increased sensitivity

PRKCE (6,268 words) [view diff] exact match in snippet view article find links to article

cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. PKCε translocates to cardiac muscle

Stem-cell therapy (9,660 words) [view diff] no match in snippet view article find links to article

cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing". Cytotherapy. 14 (2): 147–152

GroEL (5,440 words) [view diff] exact match in snippet view article find links to article

protein, has been shown to be involved in stress response as well. The heat shock response is a homeostatic mechanism that protects a cell from damage by upregulating

Anti-sigma factors (1,739 words) [view diff] exact match in snippet view article find links to article

factor σ38 Master regulator of general stress response RssB σ32 Heat shock response ≥ 37 °C Dnak σ28 Active late gene of flagellum assembly FIgM σ24

Niemann–Pick disease type C (5,153 words) [view diff] exact match in snippet view article find links to article

in 2016. Arimoclomol, which is orally administered, induces the heat shock response in cells and is well tolerated in humans.‹The template Excessive

Mitochondrial unfolded protein response (1,874 words) [view diff] exact match in snippet view article find links to article

restoration of protein homeostasis (proteostasis). In the cytosol, the heat shock response (HSR) manages the unfolded proteins through heat shock factor 1 (HSF1)

Ubiquitin C (4,261 words) [view diff] no match in snippet view article find links to article

regulation of many cellular events. Polyubiquitin-C doesn’t activate the heat-shock response, but it plays a key role in sustaining the response. UBC gene transcription

Sandro Santagata (1,492 words) [view diff] exact match in snippet view article find links to article

Biomedical Research studying the role of the master regulator of the heat shock response, HSF1, in the development of cancer. In 2013, he started his research

Rimicaris exoculata (1,272 words) [view diff] no match in snippet view article find links to article

Pierre-Marie; Jollivet, Didier; Shillito, Bruce (2003-07-15). "Heat-shock response and temperature resistance in the deep-sea vent shrimp Rimicaris

List of geneticists (7,871 words) [view diff] exact match in snippet view article find links to article

(fruit flies), in particular the genetics and biochemistry of the heat shock response. Felix Mitelman (born 1940), Swedish cancer geneticist and cytogeneticist

RNA-directed DNA methylation (14,822 words) [view diff] exact match in snippet view article find links to article

RdDM is involved in several abiotic stress responses including the heat shock response, and can silence TEs that would otherwise become active and transpose