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searching for HCV genotypes 14 found (16 total)

Sofosbuvir/velpatasvir (1,161 words) [view diff] exact match in snippet view article find links to article

older or weighing at least 37 pounds (17 kilograms) with any of the six HCV genotypes—or strains—without cirrhosis (liver disease) or with mild cirrhosis

Danoprevir (487 words) [view diff] exact match in snippet view article find links to article

clinical candidate based on its favorable potency profile against multiple HCV genotypes 1–6 and key mutants (GT1b, IC50 = 0.2–0.4 nM; replicon GT1b, EC50 =

Glecaprevir (328 words) [view diff] exact match in snippet view article find links to article

Together they demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro. On 19 December 2016, AbbVie

Elbasvir/grazoprevir (1,817 words) [view diff] no match in snippet view article find links to article

(an NS3/4A inhibitor). It is used to treat chronic hepatitis C virus (HCV) genotypes 1 or 4 infection in both treatment-naïve and treatment-experienced patients

Hepatitis C virus nonstructural protein 2 (1,152 words) [view diff] exact match in snippet view article find links to article

the HPV sequence. Its structure is indeed highly conserved between HCV genotypes, with a flexible helix in residues 3-11 and an alpha helix in residues

Sofosbuvir (5,828 words) [view diff] exact match in snippet view article find links to article

combination with other drugs is part of all first-line treatments for HCV genotypes 1, 2, 3, 4, 5, and 6, and is also part of some second-line treatments

Glecaprevir/pibrentasvir (870 words) [view diff] no match in snippet view article find links to article

older or weighing at least 99 pounds with chronic hepatitis C virus (HCV) genotypes 1–6 and both without cirrhosis and with compensated cirrhosis who have

Hepatitis C vaccine (782 words) [view diff] exact match in snippet view article find links to article

Pharmaceuticals is developing a synthetic multi-antigen DNA vaccine covering HCV genotypes 1a and 1b and targeting the HCV antigens nonstructural protein 3 (NS3)

CXCL10 (1,231 words) [view diff] exact match in snippet view article find links to article

(“first phase decline”) during interferon/ribavirin therapy for all HCV genotypes. This also applies for patients co-infected with HIV, where pre-treatment

Hepatitis C and HIV coinfection (3,550 words) [view diff] exact match in snippet view article find links to article

the individual is infected with. There are a total of six different HCV genotypes. Knowing the specific genotype of the virus is important when deciding

Patrizia Pontisso (695 words) [view diff] exact match in snippet view article find links to article

C virus and provided the first evidences of clinical differences of HCV genotypes. She then conducted research on the mechanisms of carcinogenesis, identifying

Discovery and development of NS5A inhibitors (5,211 words) [view diff] exact match in snippet view article find links to article

variability of intrinsic conformations of the D2 and D3 domains between HCV genotypes. Therefore, it is still under debate which conformation\s of NS5A is

Interferon Lambda 4 (6,064 words) [view diff] exact match in snippet view article find links to article

IFNL4 genotype and impaired HCV clearance has been observed for other HCV genotypes as well. IFNL4-ΔG/TT is the likely primary functional variant that accounts

Hepatitis C (11,864 words) [view diff] exact match in snippet view article find links to article

of treatment. A sustained response was seen in 70–80% of people with HCV genotypes 2 and 3 following 24 weeks of treatment. A sustained response occurs