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searching for Essential gene 69 found (74 total)

Patched (442 words) [view diff] exact match in snippet view article find links to article

Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations

Defective interfering particle (2,726 words) [view diff] exact match in snippet view article find links to article

classed as DIPs if they are rendered non-infectious due to at least one essential gene of the virus being lost or severely damaged as a result of the defection

Gene cluster (1,917 words) [view diff] exact match in snippet view article find links to article

the new genetic information exhibited by the duplicated copy of the essential gene would not serve a practical advantage; however, over a long, evolutionary

NuA4 histone acetyltransferase complex (381 words) [view diff] exact match in snippet view article find links to article

subunit of the complex has been identified as the product of ESA1, an essential gene required for cell cycle progression in yeast. Antibodies against Esa1p

Insertional mutagenesis (1,037 words) [view diff] exact match in snippet view article find links to article

viral DNA is inserted. If the DNA is inserted into the middle of an essential gene, the effects on the cell will be drastic. Additionally, insertion into

Histone H2A (2,082 words) [view diff] exact match in snippet view article find links to article

nucleosomes occurs in H2A.Z by binding to H1 factor. H2A.Z gene is an essential gene in yeast and it is denoted as Htz1. Comparatively, vertebrates have

Ethyl methanesulfonate (1,014 words) [view diff] exact match in snippet view article find links to article

However, since it is unlikely the same essential gene is mutated in independent gametes, and if loss of the essential gene did not kill the gamete itself, downstream

Sec14 (983 words) [view diff] exact match in snippet view article find links to article

plays a role in the localization of lipid raft proteins. Sec14p is an essential gene in yeast, and is homologous in function to phosphatidylinositol transfer

Reassortment (683 words) [view diff] exact match in snippet view article find links to article

damaged in such a way as to prevent replication or expression of an essential gene, the virus is inviable when it, alone, infects a host cell (single infection)

RAD21 (5,500 words) [view diff] exact match in snippet view article find links to article

RAD21 gene. RAD21 (also known as Mcd1, Scc1, KIAA0078, NXP1, HR21), an essential gene, encodes a DNA double-strand break (DSB) repair protein that is evolutionarily

Microviridae (2,393 words) [view diff] exact match in snippet view article find links to article

Chen M, Uchiyama A, Fane BA (2007) Eliminating the requirement of an essential gene product in an already very small virus: scaffolding protein B-free øX174

Zygosity (2,010 words) [view diff] exact match in snippet view article find links to article

Zygosity is an important factor in human medicine. If one copy of an essential gene is mutated, the (heterozygous) carrier is usually healthy. However,

Chondrocyte (1,816 words) [view diff] exact match in snippet view article find links to article

and ensures enough cells gather in the cartilage anlage. Xylt1 is an essential gene in regards to chondrocytes and proper skeletal formation, and is a key

You Are My Sunshine (2,787 words) [view diff] case mismatch in snippet view article find links to article

1967. Retrieved 2021-08-28. "GeneAutry.com: Music, Movies & More - The Essential Gene Autry, 1931-1953". www.geneautry.com. Archived from the original on

Cytophagales (3,025 words) [view diff] exact match in snippet view article find links to article

(2017), who isolated the fabZ gene in Cytophaga hutchinsonii. FabZ is an essential gene for flexirubin pigment synthesis. The FabZ mutant that failed to produce

PIAS3 (2,265 words) [view diff] exact match in snippet view article find links to article

1999). "Zimp encodes a homologue of mouse Miz1 and PIAS3 and is an essential gene in Drosophila melanogaster". Gene. 229 (1–2): 109–16. doi:10

ERB1 (176 words) [view diff] exact match in snippet view article find links to article

(September 2001). "ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAs". Nucleic

Sexual differentiation (2,821 words) [view diff] exact match in snippet view article find links to article

in females and XY in males. The Y chromosome must carry at least one essential gene which determines testicular formation (originally termed TDF). In transgenic

Thyroid hormone receptor (2,294 words) [view diff] exact match in snippet view article find links to article

with steroid hormone receptors in order to regulate the production of essential gene products. Retinoic acid receptors bind corepressors in the absence of

Rudolph, the Red-Nosed Reindeer (song) (1,729 words) [view diff] case mismatch in snippet view article

U.S. Govt. Print. Off. "GeneAutry.com: Music, Movies & More - The Essential Gene Autry, 1931-1953". Autry.com. Archived from the original on December

Fire and Ice (1983 film) (1,908 words) [view diff] no match in snippet view article

would help if you were a sex-obsessed 12-year-old boy, but it isn't essential." Gene Siskel of the Chicago Tribune gave the film two stars out of four and

Nuclear receptor 4A2 (2,223 words) [view diff] exact match in snippet view article find links to article

CH (December 2001). "Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients".

RNA-induced silencing complex (3,844 words) [view diff] exact match in snippet view article find links to article

were then transfected with Drosophila cyclin E dsRNA. Cycline E is an essential gene for cell cycle progression into the S phase. Cyclin E dsRNA arrested

Insecticide (5,130 words) [view diff] exact match in snippet view article find links to article

of double stranded RNA as a spray for potato fields. It targets the essential gene for proteasome subunit beta type-5 (PSMB5) in the Colorado potato beetle

Run Rudolph Run (1,727 words) [view diff] case mismatch in snippet view article find links to article

Rudolph Run (Chuck Berry) "GeneAutry.com: Music, Movies & More - The Essential Gene Autry, 1931-1953". www.Autry.com. Archived from the original on 2018-12-05

Reverse genetics (2,635 words) [view diff] exact match in snippet view article find links to article

yeast model system directed deletions have been created in every non-essential gene in the yeast genome. In the case of the plant model system huge mutant

Huda Zoghbi (3,612 words) [view diff] case mismatch in snippet view article find links to article

Hugo J.; Lysakowski, Anna; Zoghbi, Huda Y. (11 June 1999). "Math1: An Essential Gene for the Generation of Inner Ear Hair Cells". Science. 284 (5421): 1837–1841

RRS1 (419 words) [view diff] case mismatch in snippet view article find links to article

Miyoshi K, Tsujii R, Miyakawa T, Mizuta K (Mar 2000). "RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis

T-box transcription factor T (3,996 words) [view diff] exact match in snippet view article find links to article

aneuploidy or focal duplication. Brachyury is the most selectively essential gene in chordoma relative to other cancer types. Brachyury is associated

Calmodulin (4,221 words) [view diff] exact match in snippet view article find links to article

the cytosol and also Ca2+ spike occurs around the nucleus. DMI3, an essential gene for Nod factor signaling functions downstream of the Ca2+ spiking signature

Gaiti Hasan (837 words) [view diff] exact match in snippet view article find links to article

signaling in neurons: Unraveling specificity, compensatory mechanisms and essential gene function". Current Opinion in Neurobiology. 23 (1): 62–7. doi:10.1016/j

Teneurin (1,005 words) [view diff] exact match in snippet view article find links to article

Trzebiatowska, Agnieszka; Chiquet-Ehrismann, Ruth (2005-06-01). "ten-1, an essential gene for germ cell development, epidermal morphogenesis, gonad migration

Phosphoglucosamine mutase (345 words) [view diff] exact match in snippet view article find links to article

Mengin-Lecreulx D, van Heijenoort J (1996). "Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli". J. Biol

Porcine circovirus (1,656 words) [view diff] exact match in snippet view article find links to article

orientation to ORF1 in the genome. This gene is transcribed and is an essential gene involved in viral replication. Porcine circovirus is a replicating entity

GHMP kinase family (309 words) [view diff] exact match in snippet view article find links to article

Robinson GW (February 1991). "Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase".

Coprinopsis cinerea (1,455 words) [view diff] exact match in snippet view article find links to article

markers (requires lost gene to be inserted) or prototrophy (when causing essential gene deletion) be used for selection. Coprinopsis cinerea is known to produce

Heat shock protein (5,533 words) [view diff] exact match in snippet view article find links to article

cardiovascular Heat shock protein) as cardiac heat shock protein. Gata4 is an essential gene responsible for cardiac morphogenesis. It also regulates the gene expression

Protocell (7,479 words) [view diff] exact match in snippet view article find links to article

protocell (e.g. by blocking replication or inhibiting the function of an essential gene). Vulnerability to damage could be reduced by maintaining two or more

Sonic hedgehog protein (7,249 words) [view diff] exact match in snippet view article find links to article

subsequent sonic hedgehog protein, earning it the distinction of being an essential gene to development. The sonic hedgehog (SHH) signaling molecule assumes

Candida albicans (9,974 words) [view diff] exact match in snippet view article find links to article

Ketela T, Veillette K, Breton A, et al. (October 2003). "Large-scale essential gene identification in Candida albicans and applications to antifungal drug

Ataxia telangiectasia and Rad3 related (3,429 words) [view diff] exact match in snippet view article find links to article

Cotsarelis G, et al. (June 2007). "Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss"

Potyvirus (4,878 words) [view diff] exact match in snippet view article find links to article

Chung BY, Miller WA, Atkins JF, Firth AE (April 2008). "An overlapping essential gene in the Potyviridae". Proceedings of the National Academy of Sciences

Gene Summers (3,301 words) [view diff] case mismatch in snippet view article find links to article

Sweden Reminisce Cafe 2008, USA Taboo! 2011, USA Gotta Lotta That The Essential Gene Summers 2012, USA Rock-A-Dallas 2016, USA Country Song Roundup 2018

BOP1 (1,175 words) [view diff] exact match in snippet view article find links to article

Z, Lau LF (2001). "ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAs". Nucleic

Barakat-Perenthaler syndrome (1,174 words) [view diff] exact match in snippet view article find links to article

caused by the loss of expression of a tissue relevant isoform of an essential gene. Recently, bi-allelic loss of UDP-Glucose 6-Dehydrogenase (UGDH), another

Horizontal gene transfer (12,329 words) [view diff] exact match in snippet view article find links to article

thought to be transferred from bacteria in the beetle's gut. oskar is an essential gene for the specification of the germline in Holometabola and its origin

RNA world (10,733 words) [view diff] exact match in snippet view article find links to article

protocell (e.g., by blocking replication or inhibiting the function of an essential gene). Vulnerability to damage could be reduced by maintaining two or more

Susan Golden (2,901 words) [view diff] exact match in snippet view article find links to article

Lowe LC, Curtin G, Arkin AP, Deutschbauer A, Golden SS (2015). "The essential gene set of a photosynthetic organism". Proc Natl Acad Sci USA. 112 (48):

DNA repair-deficiency disorder (3,756 words) [view diff] exact match in snippet view article find links to article

Velez M, Bhandoola A, Brown EJ (2007). "Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss"

Joachim Lingner (1,077 words) [view diff] exact match in snippet view article find links to article

Josef; Keller, Walter (1991-12-12). "Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae". Nature. 354 (6353): 496–498

Verve Records discography (723 words) [view diff] case mismatch in snippet view article find links to article

Johnny Hodges and Wild Bill Davis Mess of Blues V/V6 8571 Gene Krupa The Essential Gene Krupa V/V6 8572 Anita O'Day Incomparable! V/V6 8573 Kai Winding Mondo

Isogenic human disease models (2,046 words) [view diff] exact match in snippet view article find links to article

Lichter NF, Fattah KR, Oh S, Hendrickson EA (June 2008). "Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic

CRISPR interference (2,898 words) [view diff] exact match in snippet view article find links to article

(2019-10-15). "Modulated efficacy CRISPRi reveals evolutionary conservation of essential gene expression-fitness relationships in bacteria". bioRxiv: 805333. doi:10

Protein inhibitor of activated STAT (3,257 words) [view diff] exact match in snippet view article find links to article

1999). "Zimp encodes a homologue of mouse Miz1 and PIAS3 and is an essential gene in Drosophila melanogaster". Gene. 229 (1–2): 109–16. doi:10

Recombinant AAV mediated genome engineering (2,673 words) [view diff] exact match in snippet view article find links to article

Lichter NF, Fattah KR, Oh S, Hendrickson EA (June 2008). "Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic

Glucosamine-phosphate N-acetyltransferase (1,602 words) [view diff] exact match in snippet view article find links to article

Yamada-Okabe H (January 1999). "Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine

Purinosome (1,672 words) [view diff] exact match in snippet view article find links to article

Field; Donald D. Anderson; Patrick J. Stover (2011). "Mthfs is an essential gene in mice and a component of the purinosome". Front Genet. 2 (36): 36

DNA damage theory of aging (11,101 words) [view diff] exact match in snippet view article find links to article

Velez M, Bhandoola A, Brown EJ (2007). "Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss"

SNED1 (2,400 words) [view diff] exact match in snippet view article find links to article

severe craniofacial and skeletal anomalies, indicating that Sned1 is an essential gene. Leimeister C, Schumacher N, Diez H, Gessler M (June 2004). "Cloning

NUMB (gene) (4,144 words) [view diff] exact match in snippet view article

Meneses JJ, Pedersen RA, Jan LY, Jan YN (June 2000). "Mouse numb is an essential gene involved in cortical neurogenesis". Proc. Natl. Acad. Sci. U.S.A. 97

Epistasis and functional genomics (1,936 words) [view diff] exact match in snippet view article find links to article

~100,000 distinct double mutant pairs. The generation of libraries of essential gene mutants presents significant difficulties however, as these mutations

Gene desert (3,459 words) [view diff] exact match in snippet view article find links to article

rather than their functions may include buffering effects. An example of essential gene deserts with inessential DNA content are the telomeres that protect

Alpha-D-phosphohexomutase superfamily (2,583 words) [view diff] exact match in snippet view article find links to article

Mengin-Lecreulx D, van Heijenoort J (January 1996). "Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli". The Journal

Helicoverpa zea nudivirus 2 (4,486 words) [view diff] exact match in snippet view article find links to article

PMID 10943556. Konrad M (December 1992). "Cloning and expression of the essential gene for guanylate kinase from yeast". The Journal of Biological Chemistry

MOP flippase (2,689 words) [view diff] exact match in snippet view article find links to article

H, Tsuji N, Fujisaki S, Kato J (November 2008). "Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli". Journal of Bacteriology

Proneural genes (5,032 words) [view diff] exact match in snippet view article find links to article

biological processes, there is evidence that ‘’daughterless (da’’) - an essential gene for the formation of the entire Drosophila peripheral nervous system

Be Honest with Me (919 words) [view diff] case mismatch in snippet view article find links to article

U.S. Govt. Print. Off. "GeneAutry.com: Music, Movies & More - The Essential Gene Autry, 1931-1953". www.geneautry.com. Retrieved 2022-02-07. Russell

Thermal shift assay (5,887 words) [view diff] exact match in snippet view article find links to article

LE, et al. (March 2005). "Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology". The Journal

Manyuan Long (2,811 words) [view diff] exact match in snippet view article find links to article

the patterns of gene origination, for example, the rapid evolution of essential gene functions in fruit flies, gene traffics between the X chromosomes and