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searching for EIF4E 46 found (97 total)

alternate case: eIF4E

EIF4E3 (165 words) [view diff] exact match in snippet view article find links to article

protein that in humans is encoded by the EIF4E3 gene. EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime

Hepatitis A virus internal ribosome entry site (IRES) (1,701 words) [view diff] exact match in snippet view article

whole complex made up of eIF4A, eIF4B, eIF4E, and eIF4G. eIF4F is used to refer to the complex that comprises eIF4E, 4G, and 4A. In cap-dependent translation

Katherine Borden (1,174 words) [view diff] exact match in snippet view article find links to article

metabolism in cancer using the eukaryotic translation initiation factor eIF4E as an exemplar. Her studies demonstrated that dysregulation of this factor

Nuclear cap-binding protein complex (1,489 words) [view diff] exact match in snippet view article find links to article

serves to control the quality of gene expression, while the translation of eIF4E-bound mRNAs serves to produce the majority of proteins. However, both of

MKNK1 (1,031 words) [view diff] exact match in snippet view article find links to article

translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E". EMBO J. 18 (1). ENGLAND: 270–9. doi:10.1093/emboj/18.1.270. ISSN 0261-4189

MIR141 (706 words) [view diff] exact match in snippet view article find links to article

host protein translation by targeting the translation initiation factor eIF4E". Cell Host Microbe. 9 (1): 58–69. doi:10.1016/j.chom.2010.12.001. PMID 21238947

VPg (731 words) [view diff] exact match in snippet view article find links to article

protein interacts directly with the cap-binding protein of the ribosome, eIF4E, and that this interaction is essential for viral translation. Principles

Sweet potato feathery mottle virus (2,446 words) [view diff] exact match in snippet view article find links to article

not known in full. After entry, helper component proteinase (HcPro) binds eIF4E, a eukaryotic cap-binding translation initiation factor that plays a crucial

Ribosome shunting (1,301 words) [view diff] exact match in snippet view article find links to article

translation. When eIF4E is abundant, the subunit binds to the 5' cap on mRNAs, forming an eIF4 complex leading to shunting; however, when eIF4E is altered or

Tikona Infinet Limited (440 words) [view diff] exact match in snippet view article find links to article

Michael J.; Elia, Androulla; Morley, Simon J. (2013). "Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis

EMX2 (948 words) [view diff] exact match in snippet view article find links to article

transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons". Proc. Natl. Acad. Sci. U.S

Dictyate (553 words) [view diff] exact match in snippet view article find links to article

remain together, then maskin binds the initiation factor eIF-4E, and thus eIF4E can no longer interact with the other initiation factors and no translation

Polysome (939 words) [view diff] exact match in snippet view article find links to article

formed by free polyadenylated mRNA in the presence of initiation factor eIF4E bound to the 5’ cap and PABP bound to the 3’-poly(A) tail. However, this

Polysome (939 words) [view diff] exact match in snippet view article find links to article

formed by free polyadenylated mRNA in the presence of initiation factor eIF4E bound to the 5’ cap and PABP bound to the 3’-poly(A) tail. However, this

Nektarios Tavernarakis (4,304 words) [view diff] exact match in snippet view article find links to article

N (2018). "Maintenance of proteostasis by P body-mediated regulation of eIF4E availability during ageing in Caenorhabditis elegans". Cell Reports. 25

PIM2 (gene) (1,992 words) [view diff] exact match in snippet view article

inhibition of the interaction between the translation initiation factors eIF4E and eIF4G". Cell. 128 (2): 257–67. doi:10.1016/j.cell.2006.11.046. PMID 17254965

HHEX (1,534 words) [view diff] exact match in snippet view article find links to article

proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth". The EMBO Journal. 22 (3):

UPF2 (1,292 words) [view diff] exact match in snippet view article find links to article

(Jul 2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". The EMBO Journal

Gabriella Gobbi (1,380 words) [view diff] exact match in snippet view article find links to article

Antidepressant actions of ketamine engage cell-specific translation via eIF4E. Nature, 590(7845), 315-319. "Dr. Gabriella Gobbi's Lab: Background". "Gabriella

Follicular dendritic cell sarcoma (2,551 words) [view diff] exact match in snippet view article find links to article

Pelletier, Jerry; Lowe, Scott W. (2004). "Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy". Nature. 428 (6980): 332–7. Bibcode:2004Natur

Argonaute (1,972 words) [view diff] exact match in snippet view article find links to article

homologue structure proposed to mimic the cap-binding structure motif found in eIF4E. It was later found that the MC motif is not involved in mRNA cap binding

TLK1 (1,213 words) [view diff] exact match in snippet view article find links to article

Meschonat C, Debenedetti A, Li BD (Jan 2004). "TLK1B is elevated with eIF4E overexpression in breast cancer". The Journal of Surgical Research. 116

UPF3B (1,176 words) [view diff] exact match in snippet view article find links to article

LE (2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". EMBO J. 21

Plant disease resistance (7,555 words) [view diff] case mismatch in snippet view article find links to article

barley. Natural alleles of host translation elongation initiation factors eif4e and eif4g are also recessive viral-resistance genes. Some have been deployed

RNPS1 (1,242 words) [view diff] exact match in snippet view article find links to article

(Jul 2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". The EMBO Journal

SRRM1 (978 words) [view diff] exact match in snippet view article find links to article

LE (2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". EMBO J. 21

RBM8A (1,257 words) [view diff] exact match in snippet view article find links to article

LE (2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". EMBO J. 21

TILLING (molecular biology) (1,335 words) [view diff] exact match in snippet view article

(2007). "EcoTILLING for the identification of allelic variants of melon eIF4E, a factor that controls virus susceptibility". BMC Plant Biology. 7: 34

Viral eukaryogenesis (1,640 words) [view diff] exact match in snippet view article find links to article

capped mRNA and contain homologues of the eukaryotic cap-binding protein eIF4E. Those supporting viral eukaryogenesis also point to the lack of these features

Doxorubicin (4,504 words) [view diff] exact match in snippet view article find links to article

A, Ray S, Kogan S, et al. (March 2004). "Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy". Nature. 428 (6980): 332–337. Bibcode:2004Natur

C15orf39 (1,090 words) [view diff] exact match in snippet view article find links to article

nucleocytoplasmic protein that shuttles the translation initiation factor eIF4E between the nucleus and cytoplasm. The protein interaction between C15orf39

Translation regulation by 5′ transcript leader cis-elements (1,680 words) [view diff] exact match in snippet view article find links to article

Sonenberg, Nahum (February 2005). "Regulation of cap-dependent translation by eIF4E inhibitory proteins". Nature. 433 (7025): 477–480. Bibcode:2005Natur.433

Exercise (10,562 words) [view diff] exact match in snippet view article find links to article

4EBP1: eukaryotic translation initiation factor 4E-binding protein 1 • eIF4E: eukaryotic translation initiation factor 4E • RPS6: ribosomal protein

John H. Healey (1,057 words) [view diff] exact match in snippet view article find links to article

PMID 21584898. Osborne TS, Ren L, Healey JH, et al. (October 2011). "Evaluation of eIF4E expression in an osteosarcoma-specific tissue microarray". J. Pediatr. Hematol

Exon junction complex (2,530 words) [view diff] exact match in snippet view article find links to article

(2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling". EMBO J. 21

Tumstatin (1,492 words) [view diff] exact match in snippet view article find links to article

also prevents the dissociation of eukaryotic initiation factor 4E protein (eIF4E) from 4Ebinding protein 1. These pathways are involved in cell proliferation

Jeffrey Hill (1,460 words) [view diff] exact match in snippet view article find links to article

; Rizzieri, David A.; Tan, Soo Yong (2013-06-18). "Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell

Adenovirus early region 1A (2,233 words) [view diff] exact match in snippet view article find links to article

initiation factor. Adenovirus likely displaces Mnk1 from eIF4G and inhibits eIF4E phosphorylation, both of which are important components of the eIF4a translation

Stress granule (12,460 words) [view diff] exact match in snippet view article find links to article

S, Venturi V, Pospisek M (August 2016). "Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules". BMC Molecular Biology

Cassava brown streak virus disease (2,278 words) [view diff] exact match in snippet view article find links to article

Rebecca S. (2018). "Simultaneous CRISPR/Cas9-mediated editing of cassava eIF4E isoforms nCBP-1 and nCBP-2 reduces cassava brown streak disease symptom

Β-Hydroxy β-methylbutyric acid (9,982 words) [view diff] exact match in snippet view article find links to article

4EBP1: eukaryotic translation initiation factor 4E-binding protein 1 • eIF4E: eukaryotic translation initiation factor 4E • RPS6: ribosomal protein

KIAA2013 (1,669 words) [view diff] exact match in snippet view article find links to article

Simons M, Hla T (December 2014). "ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis". Proceedings of the National

Alex Kentsis (1,797 words) [view diff] exact match in snippet view article find links to article

Topisirovic I, Culjkovic B, Shao L, Borden KL (2004). "Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine

Eric Klann (1,310 words) [view diff] exact match in snippet view article find links to article

(2011) Inhibition of the interactions between translation initiation factors eIF4E and eIF4G impairs long-term associative memory consolidation but not reconsolidation

WDR88 (2,370 words) [view diff] exact match in snippet view article find links to article

Sonenberg N, Gingras AC (April 1998). "The mRNA 5' cap-binding protein eIF4E and control of cell growth". Current Opinion in Cell Biology. 10 (2): 268–275

Lily mottle virus (3,420 words) [view diff] exact match in snippet view article find links to article

potyviruses also interacts directly with the translation initiation factors eIF4E and eIFiso4E. This could represent an as yet uncharacterized, Cap- and IRES-independent