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searching for Developmental toxicity 95 found (119 total)

Piperonyl butoxide (2,709 words) [view diff] case mismatch in snippet view article find links to article

Alexander A.; McLaughlin, Matthew T.; Lipinski, Robert J. (2019). "Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog

Indole-3-acetic acid (2,769 words) [view diff] no match in snippet view article find links to article

Indole-3-acetic acid (IAA, 3-IAA) is the most common naturally occurring plant hormone of the auxin class. It is the best known of the auxins, and has

Joseph F. Holson (4,198 words) [view diff] exact match in snippet view article find links to article

Holson's career, while at NCTR, he led studies that assessed the developmental toxicity of FD&C Red No. 2, an amaranth dye, and the herbicide 2,4,5‐T (a

OECD Guidelines for the Testing of Chemicals (152 words) [view diff] case mismatch in snippet view article find links to article

Reproduction/Developmental Toxicity Screening Test 422 Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Nivalenol (3,570 words) [view diff] exact match in snippet view article find links to article

acute/subacute, subchronic, chronic and carcinogenicity, genotoxicity, developmental toxicity studies and studies on reproduction, immunotoxicity/hematotoxycity

Monobenzyl phthalate (350 words) [view diff] exact match in snippet view article find links to article

PMID 29328989. Ema M, Harazono A, Miyawaki E, Ogawa Y (July 1996). "Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the

Lithium hypochlorite (318 words) [view diff] exact match in snippet view article find links to article

Hoberman A. M.; Deprospo J. R.; Lochry E. A.; Christian M. S. (1990). "Developmental toxicity study of orally administered lithium hypochlorite in rats". Journal

Heneicosane (348 words) [view diff] exact match in snippet view article find links to article

Lomash, V; Jatav, PC; Kumar, A; Pant, SC (January 2016). "Prenatal developmental toxicity study of n-heneicosane in Wistar rats". Toxicology and Industrial

Gambogic acid (1,167 words) [view diff] exact match in snippet view article find links to article

the mouse central nervous system. In mice gambogic acid causes developmental toxicity in a dose-dependent manner, including low birth weight and inhibitory

Homosalate (802 words) [view diff] exact match in snippet view article find links to article

Jarry H, Wuttke W, Lichtensteiger W (2004). "Endocrine activity and developmental toxicity of cosmetic UV filters--an update". Toxicology. 205 (1–2): 113–122

Herbal Essences (574 words) [view diff] exact match in snippet view article find links to article

2023. Herbal Essences Official website Daston GP (August 2004). "Developmental toxicity evaluation of butylparaben in Sprague-Dawley rats". Birth Defects

Prallethrin (1,070 words) [view diff] exact match in snippet view article find links to article

toxicity studies (subchronic and chronic oral studies in dogs, developmental toxicity studies in the rat and rabbit, 21-day dermal and 28-day inhalation

Antimony trioxide (1,083 words) [view diff] case mismatch in snippet view article find links to article

E.; Schroeder, R. E.; Zwick, L.; Serex, T. (2004). "Inhalation Developmental Toxicity Studies In Rats With Antimony(III) oxide (Sb2O3)". Toxicologist

Food additive (2,099 words) [view diff] exact match in snippet view article find links to article

data) and chronic toxicity and carcinogenity; reproductive and developmental toxicity. A subset of food additives, micronutrients added in food fortification

Tasimelteon (1,110 words) [view diff] exact match in snippet view article find links to article

studies, administration of tasimelteon during pregnancy resulted in developmental toxicity (embryofetal mortality, neurobehavioral impairment, and decreased

Nickel(II) sulfate (1,004 words) [view diff] exact match in snippet view article

studies of highly exposed female workers have not shown adverse developmental toxicity effects. K. Lascelles, L. G. Morgan, D. Nicholls, D. Beyersmann

N-Methyl-2-pyrrolidone (711 words) [view diff] exact match in snippet view article find links to article

H319, H335). Studies show NMP exposure can increase the risk of developmental toxicity, including miscarriage and fetal death.: 24 Good ventilation and

In vitro (3,125 words) [view diff] exact match in snippet view article find links to article

based kinetic modeling to predict dose–response curves for in vivo developmental toxicity of glycol ethers in rat and man". Toxicological Sciences. 118 (2):

Boric acid (5,640 words) [view diff] exact match in snippet view article find links to article

residents living near boron-rich regions) produced no indicators of developmental toxicity in blood and semen tests. The highest estimated exposure was 5 mg

ISO 10993 (435 words) [view diff] case mismatch in snippet view article find links to article

Hemocompatibility Chronic Toxicity Carcinogenicity Reproductive/Developmental Toxicity Degradation Category Contact Surface device Intact skin A X X X

Methemoglobinemia (2,558 words) [view diff] exact match in snippet view article find links to article

an update on methemoglobinemia occurrence and reproductive and developmental toxicity". Regulatory Toxicology and Pharmacology. 23 (1 Pt 1): 35–43. doi:10

Ponceau 4R (751 words) [view diff] exact match in snippet view article find links to article

carcinogenicity, genotoxicity, neurotoxicity, or reproductive and developmental toxicity at the permitted dietary exposures; the European acceptable daily

CYP2J2 (1,896 words) [view diff] exact match in snippet view article find links to article

biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity". Toxicology and Applied Pharmacology. 165 (2): 158–62. doi:10.1006/taap

Plasticizer (2,692 words) [view diff] exact match in snippet view article find links to article

have been classified as potential endocrine disruptors with some developmental toxicity reported. Plasticizers can escape plastics due to migration and

Sunset yellow FCF (1,131 words) [view diff] exact match in snippet view article find links to article

: 465 Sunset yellow FCF has no carcinogenicity, genotoxicity, or developmental toxicity in the amounts at which it is used.: 465 It has been claimed since

Bevirimat (1,671 words) [view diff] exact match in snippet view article find links to article

potential for cytotoxicity. There is no evidence of any reproductive or developmental toxicity and it is not immunotoxic. Bevirimat was initially evaluated for

Chilean rose tarantula (1,358 words) [view diff] exact match in snippet view article find links to article

(2013). "Old World vs. New World: a preliminary comparison of the developmental toxicity of venom from two tarantula species, Grammostola rosea and Haplopelma

ZebraBox (360 words) [view diff] exact match in snippet view article find links to article

Wang W, Ma Q, Ding X, Xu Y, He M, Xu J, et al. (March 2022). "Developmental toxicity of bromoacetamide via the thyroid hormone receptors-mediated disruption

Cyanazine (1,713 words) [view diff] case mismatch in snippet view article find links to article

"Characterization of Maternal Influence on Teratogenicity: An Assessment of Developmental Toxicity Studies for the Herbicide Cyanazine1,2," Regul. Toxicol. Pharmacol

Protein (10,957 words) [view diff] case mismatch in snippet view article find links to article

National Research Council (US) Subcommittee on Reproductive and Developmental Toxicity (2001), "Experimental Animal and In Vitro Study Designs", Evaluating

Perfluorooctanesulfonic acid (5,377 words) [view diff] exact match in snippet view article find links to article

PMID 11999053. Lau C, Butenhoff JL, Rogers JM (July 2004). "The developmental toxicity of perfluoroalkyl acids and their derivatives". Toxicol. Appl. Pharmacol

Iodopropynyl butylcarbamate (826 words) [view diff] exact match in snippet view article find links to article

be a non-carcinogen with no genotoxicity and in reproductive and developmental toxicity studies using rats and mice, IPBC had no significant effect on fertility

Hydroxycarbamide (1,843 words) [view diff] exact match in snippet view article find links to article

(August 2007). "NTP-CERHR expert panel report on the reproductive and developmental toxicity of hydroxyurea". Birth Defects Research. Part B, Developmental and

Conium maculatum (2,862 words) [view diff] exact match in snippet view article find links to article

Forsyth, Carol S.; Frank, Anthony A. (July 1993). "Evaluation of developmental toxicity of coniine to rats and rabbits". Teratology. 48 (1): 59–64. doi:10

Bis(2-ethylhexyl) terephthalate (548 words) [view diff] exact match in snippet view article

[sic] to DEHP, has been shown to have potential reproductive and developmental toxicity." The NOAELs quoted are actually quite high, indicating the potential

Platinum nanoparticle (5,347 words) [view diff] exact match in snippet view article find links to article

through protein levels. Last is the developmental toxicity that can occur as an organism grows. Developmental toxicity looks at the impact the nanoparticle

Polychlorinated dibenzodioxins (6,921 words) [view diff] exact match in snippet view article find links to article

Kransler KM, McGarrigle BP, Olson JR (January 2007). "Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the hamster, rat and guinea

Cosmetology (4,227 words) [view diff] exact match in snippet view article find links to article

Donald, J. M; Hooper, K; Hopenhayn-Rich, C (1991). "Reproductive and developmental toxicity of toluene: A review". Environmental Health Perspectives. 94: 237–44

Polyethylene glycol (4,161 words) [view diff] case mismatch in snippet view article find links to article

May 2017. Andersen FA (1999). "Special Report: Reproductive and Developmental Toxicity of Ethylene Glycol and Its Ethers". International Journal of Toxicology

Safflower (3,017 words) [view diff] exact match in snippet view article find links to article

grade safflower concentrate: No evidence for reproduction and early developmental toxicity". Reproductive Toxicology. 104: 155–165. doi:10.1016/j.reprotox

Tetrachloroethylene (2,739 words) [view diff] exact match in snippet view article find links to article

Grandjean P, Landrigan PJ (March 2014). "Neurobehavioural effects of developmental toxicity". The Lancet. Neurology. 13 (3): 330–8. doi:10.1016/S1474-4422(13)70278-3

Mir-430 microRNA precursor family (784 words) [view diff] exact match in snippet view article find links to article

Schönbach C (ed.). "Analysis of microRNA expression in embryonic developmental toxicity induced by MC-RR". PLOS ONE. 6 (7): e22676. Bibcode:2011PLoSO..

Uranium in the environment (3,481 words) [view diff] exact match in snippet view article find links to article

PMID 12539863. S2CID 25310165. J. L. Domingo (2001). "Reproductive and developmental toxicity of natural and depleted uranium: a review". Reprod. Toxicol. 15

N-Nitroso-N-methylurea (407 words) [view diff] case mismatch in snippet view article find links to article

and Mutagenesis 11:1-10. Faustman, E., et al. (1989). In Vitro Developmental Toxicity of Five Direct-Acting Alkylating Agents in Rodent Embryos: Structure-Activity

Nimetazepam (1,799 words) [view diff] exact match in snippet view article find links to article

Takeno S, Hirano Y, Kitamura A, Sakai T (August 1993). "Comparative developmental toxicity and metabolism of nitrazepam in rats and mice". Toxicology and Applied

Chromium(III) phosphate (1,667 words) [view diff] exact match in snippet view article

affected. This may ultimately lead to nephrotoxicity, reproductive and developmental toxicity due to tissue damage, necrosis and inflammation. Mustafa, S.; Murtaza

Vibegron (2,260 words) [view diff] exact match in snippet view article find links to article

vibegron during the period of organogenesis and showed no embryo-fetal developmental toxicity up to 300 mg/kg/day. Similar data was found in rabbits. Maternal

Salicylic acid (3,382 words) [view diff] exact match in snippet view article find links to article

cosmetic products demonstrates no evidence of a health risk from developmental toxicity". Regulatory Toxicology and Pharmacology. 94: 245–251. doi:10.1016/j

Bread (6,767 words) [view diff] exact match in snippet view article find links to article

Acrylamide is neurotoxic, has adverse effects on male reproduction and developmental toxicity and is carcinogenic. A study has found that more than 99 percent

Manganism (2,471 words) [view diff] exact match in snippet view article find links to article

Treinen, Kimberley A.; Gray, Tim J. B.; Blazak, William F. (1995). "Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley

Magnetofection (2,414 words) [view diff] exact match in snippet view article find links to article

"Effects of iron oxide nanoparticles: Cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity". Environmental and Molecular Mutagenesis. 56

Iodoacetic acid (1,075 words) [view diff] case mismatch in snippet view article find links to article

(1996). "Quantitative Structure-Activity Relationships for the Developmental Toxicity of Haloacetic Acids in Mammalian Whole Embryo Culture". Teratology

Borax (4,529 words) [view diff] exact match in snippet view article find links to article

residents living near boron rich regions) produced no indicators of developmental toxicity in blood and semen tests. The highest estimated exposure was 5 mg

Benzyl butyl phthalate (3,118 words) [view diff] exact match in snippet view article find links to article

Reproduction : phthalates expert panel report on the reproductive and developmental toxicity of butyl benzyl phthalate ଝ (Vol. 16) NTP - CERHR. (2003). NTP-CERHR

Thallium (5,779 words) [view diff] exact match in snippet view article find links to article

exposure to thallium increases the risk of reproductive toxicity or developmental toxicity. Chronic high level exposure to thallium through inhalation has

T-2 mycotoxin (3,186 words) [view diff] exact match in snippet view article find links to article

Zhang T, Zhao J, Huang L, Peng S (April 2014). "T-2 toxin induces developmental toxicity and apoptosis in zebrafish embryos". Journal of Environmental Sciences

Diisobutyl phthalate (3,409 words) [view diff] exact match in snippet view article find links to article

2012). "Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency"

1,1,1,3,3,3-Hexachloropropane (978 words) [view diff] exact match in snippet view article find links to article

S. M. Munley, M. S. Swanson, K. M. McGown, M. E. Hurtt (2003): "Developmental toxicity and genotoxicity studies of 1,1,1,3,3,3-hexachloropropane (HCC-230fa)

In vitro to in vivo extrapolation (746 words) [view diff] exact match in snippet view article find links to article

based kinetic modeling to predict dose–response curves for in vivo developmental toxicity of glycol ethers in rat and man". Toxicological Sciences. 118 (2):

Bisphenol S (3,589 words) [view diff] case mismatch in snippet view article find links to article

Gaballah, Shaza; Lamendella, Regina; Tal, Tamara (2019-02-01). "Host Developmental Toxicity of BPA and BPA Alternatives Is Inversely Related to Microbiota Disruption

Indo-Pacific humpback dolphin (4,039 words) [view diff] exact match in snippet view article find links to article

marine mammals such as disease susceptibility, reproductive and developmental toxicity. Constant absorption of organic pollutants like plastic can be transferred

Persistent organic pollutant (5,526 words) [view diff] exact match in snippet view article find links to article

studies are ongoing, but it shows neuroendocrine disruption and developmental toxicity in animal studies. Hexabromodiphenyl ether (hexaBDE) and heptabromodiphenyl

Perfluorooctanoic acid (13,081 words) [view diff] exact match in snippet view article find links to article

hormone levels at very high concentrations. Animal studies show developmental toxicity from reduced birth size, physical developmental delays, endocrine

Methoxyacetic acid (514 words) [view diff] exact match in snippet view article find links to article

one-carbon moieties in 2-methoxyethanol and 2-methoxyacetic acid-induced developmental toxicity". Toxicology and Applied Pharmacology. 99 (1): 98–109. doi:10

Imidacloprid (4,909 words) [view diff] exact match in snippet view article find links to article

by the U.S. EPA (group E). It is not listed for reproductive or developmental toxicity, but is listed on EPA's Tier 1 Screening Order for chemicals to

Rabbit (12,875 words) [view diff] exact match in snippet view article find links to article

Carney, Edward W (2000). "The rabbit as a model for reproductive and developmental toxicity studies". Reproductive Toxicology. 14 (6): 477–493. Bibcode:2000RepTx

JeAnne Burg (487 words) [view diff] exact match in snippet view article find links to article

Kirby N. (1987), "Evaluation of 60 chemicals in a preliminary developmental toxicity test", Teratogenesis, Carcinogenesis, and Mutagenesis, 7 (1), Wiley:

Nickel (10,153 words) [view diff] exact match in snippet view article find links to article

studies of highly exposed female workers have not shown adverse developmental toxicity effects. People can be exposed to nickel in the workplace by inhalation

Pharmacy automation (2,705 words) [view diff] exact match in snippet view article find links to article

characteristics in humans or animals: carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity, organ toxicity at low doses, genotoxicity

Hedgehog signaling pathway (6,910 words) [view diff] case mismatch in snippet view article find links to article

Fink DM, Heyne GW, Melberg CG, Nelson KF, et al. (October 2019). "Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog

Microcystin-LR (3,054 words) [view diff] exact match in snippet view article find links to article

passes the intestinal barrier. Microcystins do not appear to show developmental toxicity. The WHO states microcystin-LR has no mutagenic effect. However

Novaluron (1,561 words) [view diff] exact match in snippet view article find links to article

effects were noted up to a dose of 1000 mg/kg/day and no maternal or developmental toxicity was noted. Based on available studies, there is also no concern

Aflatoxin B1 (3,654 words) [view diff] exact match in snippet view article find links to article

PMC 6359889. PMID 19642212. Geissler F, Faustman EM (February 1988). "Developmental toxicity of aflatoxin B1 in the rodent embryo in vitro: contribution of exogenous

Scathophaga stercoraria (2,771 words) [view diff] case mismatch in snippet view article find links to article

00984.x. PMID 22007907. Oecd (2008). Test No. 228: Determination of Developmental Toxicity of a Test Chemical to Dipteran Dung Flies (Scathophaga stercoraria

Endosulfan (7,079 words) [view diff] exact match in snippet view article find links to article

hormones and animal studies have demonstrated its reproductive and developmental toxicity, especially among males. A number of studies have documented that

Methanol economy (6,182 words) [view diff] case mismatch in snippet view article find links to article

(2004). "NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Methanol". Reproductive Toxicology. 18 (3): 303–390. Bibcode:2004RepTx

Zebrafish (12,449 words) [view diff] case mismatch in snippet view article find links to article

"Automated Morphological Feature Assessment for Zebrafish Embryo Developmental Toxicity Screens". Toxicological Sciences. 167 (2): 438–449. doi:10.1093/toxsci/kfy250

Glyphosate (16,484 words) [view diff] exact match in snippet view article find links to article

Kimmel GL, Kimmel CA, Williams AL, DeSesso JM (2013). "Evaluation of developmental toxicity studies of glyphosate with attention to cardiovascular development"

Electronic waste (16,589 words) [view diff] exact match in snippet view article find links to article

in mice have found the following health effects: Hepatotoxicity, developmental toxicity, immunotoxicity, hormonal effects and carcinogenic effects. Studies

CompuCell3D (2,070 words) [view diff] exact match in snippet view article find links to article

and biomedical research fields, including developmental biology, developmental toxicity, cancer biology, toxicology, immunology, and tissue engineering

Toxic Substances Control Act of 1976 (11,565 words) [view diff] exact match in snippet view article find links to article

Koduru, Sudha (June 1, 2000). "Chemicals in the environment and developmental toxicity to children: a public health and policy perspective". Environmental

Toxicodynamics (3,269 words) [view diff] case mismatch in snippet view article find links to article

Toxicological Characteristics of Endocrine-Disrupting Chemicals: Developmental Toxicity, Carcinogenicity, and Mutagenicity. Journal of Toxicology and Environmental

Pharmacoepigenetics (4,224 words) [view diff] exact match in snippet view article find links to article

mass spectrometry-based histone screening for assessing epigenetic developmental toxicity". Scientific Reports. 12 (1): 1256. doi:10.1038/s41598-022-05268-x

Topical fluoride (2,663 words) [view diff] exact match in snippet view article find links to article

development. While the exact pathophysiology of fluoride-induced developmental toxicity is not completely understood, most research suggested that excessive

Nutritional neuroscience (15,340 words) [view diff] exact match in snippet view article find links to article

Treinen, Kimberley A.; Gray, Tim J. B.; Blazak, William F. (1995). "Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley

Diafenthiuron (1,589 words) [view diff] exact match in snippet view article find links to article

Gao, Bo; Xiao, Peng; Li, Wenhua (May 2023). "Diafenthiuron causes developmental toxicity in zebrafish (Danio rerio)". Chemosphere. 323: 138253. Bibcode:2023Chmsp

Composition of electronic cigarette aerosol (12,834 words) [view diff] exact match in snippet view article find links to article

chloride 0.09 cerebellar lesions U.S. EPA Methyl ethyl ketone 5 developmental toxicity U.S. EPA Naphthalene 0.003 nasal effects U.S. EPA N-nitrosodi-n-butylamine

Health effects of electronic cigarettes (22,800 words) [view diff] exact match in snippet view article find links to article

Bloch M, Conway K, Cosgrove K, Grana R, et al. (January 2017). "Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for

Cancer epigenetics (12,533 words) [view diff] exact match in snippet view article find links to article

mass spectrometry-based histone screening for assessing epigenetic developmental toxicity". Scientific Reports. 12 (1): 1256. Bibcode:2022NatSR..12.1256V

Electronic cigarette and e-cigarette liquid marketing (18,273 words) [view diff] exact match in snippet view article find links to article

Theodore A.; Spindel, Eliot; Stroud, Laura; Wakschlag, Lauren (2017). "Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for

Single-walled carbon nanohorn (7,074 words) [view diff] exact match in snippet view article find links to article

assessments, including chronic (repeated dose), reproductive, and developmental toxicity studies, are still needed, yet the present results strongly suggest

Ethyl lauroyl arginate (3,566 words) [view diff] exact match in snippet view article find links to article

humans, mutagenic, acute, subchronic, chronic, reproductive, and developmental toxicity. The results of these studies have been published in the prestigious

Darryl B. Hood (2,225 words) [view diff] exact match in snippet view article find links to article

Hood DB, Ramesh A, Chirwa S, Khoshbouei H, Archibong AE (2011). "Developmental toxicity of polycyclic aromatic hydrocarbons". Reproductive and Developmental

Bis(2-ethylhexyl)tetrabromophthalate (2,807 words) [view diff] exact match in snippet view article

the European Union, which resulted in a request for a prenatal developmental toxicity study. A compliance check (the testing of products manufactured

Seed oil misinformation (3,782 words) [view diff] exact match in snippet view article find links to article

testing for subchronic toxicity, oncogenicity, reproductive toxicity, developmental toxicity, mutagencity, neurotoxicity, and inhalation and dermal pharmacokinetics