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Longer titles found: Death Domain database (view), Leucine-rich repeats and death domain containing 1 (view)

searching for Death domain 124 found (148 total)

alternate case: death domain

Fas receptor (2,664 words) [view diff] exact match in snippet view article find links to article

This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. FADD also contains a death effector domain (DED) near
EDARADD (482 words) [view diff] exact match in snippet view article find links to article
protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for
Tumor necrosis factor receptor 1 (2,176 words) [view diff] exact match in snippet view article find links to article
"Tumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domain". Mol. Cell. Biol. 22 (8): 2536–43. doi:10.1128/MCB.22.8.2536-2543.2002
Death receptor 4 (1,020 words) [view diff] exact match in snippet view article find links to article
cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by
Decoy receptor 2 (897 words) [view diff] exact match in snippet view article find links to article
TRAIL-binding domain, a transmembrane domain, and a truncated cytoplasmic death domain. This receptor does not induce apoptosis, and has been shown to play
Tumor necrosis factor (4,947 words) [view diff] exact match in snippet view article find links to article
likely underestimated. At least partly because TNFR2 has no intracellular death domain, it shows neuroprotective properties. Upon contact with their ligand
Death receptor 3 (1,586 words) [view diff] no match in snippet view article find links to article
DV, Giles KM, Pun KT, Grinham CJ, Brown R, Farrow SN (Nov 1996). "A death-domain-containing receptor that mediates apoptosis". Nature. 384 (6607): 372–5
TRAIL (1,303 words) [view diff] exact match in snippet view article find links to article
which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). DcR1 functions as a TRAIL-neutralizing decoy-receptor. The cytoplasmic
Caspase-10 (248 words) [view diff] exact match in snippet view article find links to article
ICE-like apoptotic protease 4, apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1beta-converting enzyme 2) is an enzyme. This enzyme
Caspase 8 (2,274 words) [view diff] exact match in snippet view article find links to article
Stillman DJ, Thorburn A (September 2002). "Regulation of Fas-associated death domain interactions by the death effector domain identified by a modified reverse
Low-affinity nerve growth factor receptor (4,042 words) [view diff] exact match in snippet view article find links to article
say that, in contrast to the type I death domain found in other TNFR proteins, the type II intracellular death domain of p75NTR does nor self-associated
Death-inducing signaling complex (992 words) [view diff] exact match in snippet view article find links to article
receptor, or CD95), a tumor necrosis factor containing a functional death domain. This association leads to the formation of the DISC, thereby inducing
Decoy receptor 1 (978 words) [view diff] exact match in snippet view article find links to article
TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to
CRADD (923 words) [view diff] exact match in snippet view article find links to article
Death domain-containing protein CRADD is a protein that in humans is encoded by the CRADD gene. The protein encoded by this gene is a death domain (CARD/DD)-containing
RIPK1 (4,110 words) [view diff] exact match in snippet view article find links to article
contains a serine/threonine kinase domain (KD) in the 300 aa N-Terminus, a death domain (DD) in the 112 aa C-Terminus, and a central region between the KD and
Cleric (Dungeons & Dragons) (2,369 words) [view diff] case mismatch in snippet view article
or War. In addition to those, the Dungeon Master`s Guide contains the Death Domain under the Villainous Class Options section. Several sourcebooks since
DAPK1 (1,168 words) [view diff] exact match in snippet view article find links to article
autophagy • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • apoptotic signaling pathway • protein autophosphorylation
MADD (gene) (1,048 words) [view diff] exact match in snippet view article
MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling
Caspase 2 (918 words) [view diff] exact match in snippet view article find links to article
domain, including RIP-associated Ich-1/Ced-3-homologue protein with a death domain (RAIDD), apoptosis repressor with caspase recruitment domain (ARC), and
Anoikis (765 words) [view diff] exact match in snippet view article find links to article
Simpson CD, Hurren R, et al. (May 2007). "Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis
Caspase 10 (1,469 words) [view diff] exact match in snippet view article find links to article
PMID 15659383. Vincenz, C; Dixit V M (March 1997). "Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3
Ectodysplasin A receptor (1,666 words) [view diff] exact match in snippet view article find links to article
Overbeek PA (2002). "Gene defect in ectodermal dysplasia implicates a death domain adapter in development". Nature. 414 (6866): 913–6. doi:10.1038/414913a
CFLAR (275 words) [view diff] exact match in snippet view article find links to article
necroptotic process • regulation of extrinsic apoptotic signaling pathway via death domain receptors • GO:0022415 viral process • apoptotic process • GO:0048554
Lymphoproliferative disorders (763 words) [view diff] exact match in snippet view article find links to article
the TNF-receptor superfamily (TNFRSF6). The Fas receptor contains a death domain and has been shown to play a central role in the physiological regulation
BAG4 (812 words) [view diff] exact match in snippet view article find links to article
activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3
HMOX1 (675 words) [view diff] exact match in snippet view article find links to article
substance • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • angiogenesis • intrinsic apoptotic signaling pathway in response
Caspase (3,098 words) [view diff] exact match in snippet view article find links to article
of the receptor. The adaptor protein FADD will recruit (by a Death domain-Death domain interaction) pro-Caspase 8 via the DED domain. This FasR, FADD
TRAF2 (3,714 words) [view diff] exact match in snippet view article find links to article
S, Fairbrother WJ, Dixit VM (March 2002). "Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated
Chromosome 11 (1,777 words) [view diff] exact match in snippet view article find links to article
fibronectin type III domain containing 4 MADD: MAP kinase-activating death domain protein MEN1: Multiple endocrine neoplasia type 1 MIRLET7A2: microRNA
Ankyrin (967 words) [view diff] exact match in snippet view article find links to article
24 tandem ankyrin repeats, a central domain that binds to spectrin, a death domain that binds to proteins involved in apoptosis, and a C-terminal regulatory
Tumor necrosis factor receptor 2 (904 words) [view diff] exact match in snippet view article find links to article
antioxidative pathways. At least partly because TNRF2 has no intracellular death domain, TNFR2 is neuroprotective. TNFRSF1B has been shown to interact with:
MYD88 (2,687 words) [view diff] no match in snippet view article find links to article
Martin TE, Fakan S (August 1998). "Ultrastructural distribution of the death-domain-containing MyD88 protein in HeLa cells". Experimental Cell Research.
STK4 (1,023 words) [view diff] exact match in snippet view article find links to article
development • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of protein phosphorylation • GO:0007243
BMPR1B (523 words) [view diff] exact match in snippet view article find links to article
development • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • skeletal system development • cell differentiation • limb
HMGB2 (1,189 words) [view diff] exact match in snippet view article find links to article
bacterium • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • V(D)J recombination • spermatogenesis • positive regulation
NFKB2 (1,273 words) [view diff] exact match in snippet view article find links to article
v t e PDB gallery 1a3q: HUMAN NF-KAPPA-B P52 BOUND TO DNA 2d96: Solution structure of the Death domain of Nuclear factor NF-kappa-B p100
BinCARD (904 words) [view diff] no match in snippet view article find links to article
encoded by the C9orf89 gene on chromosome 9. BinCARD is a member of the death-domain superfamily and contains a caspase recruitment domain (CARD). This protein
Toll-Interleukin receptor (808 words) [view diff] case mismatch in snippet view article find links to article
adaptor protein found in mammals, contains a TIR domain associated to a DEATH domain (see InterPro: IPR000488). Besides the mammalian and Drosophila melanogaster
ICAM-1 (2,311 words) [view diff] exact match in snippet view article find links to article
activity • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of vasoconstriction • cellular response
Apoptosis (10,357 words) [view diff] exact match in snippet view article find links to article
intermediate membrane proteins TNF receptor-associated death domain (TRADD) and Fas-associated death domain protein (FADD). cIAP1/2 can inhibit TNF-α signaling
Nerve growth factor (4,565 words) [view diff] exact match in snippet view article find links to article
and PCD mechanisms are mediated through adaptor protein binding to the death domain of the p75NTR cytoplasmic tail. Survival occurs when recruited cytoplasmic
MALT1 (2,688 words) [view diff] exact match in snippet view article find links to article
receptors. Sequence analysis proposes that paracaspase has an N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the
CENPC1 (931 words) [view diff] exact match in snippet view article find links to article
"Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death". J. Cell Sci.
LIGHT (protein) (1,801 words) [view diff] no match in snippet view article
Goddard A, Ashkenazi A (April 1998). "Identification of a ligand for the death-domain-containing receptor Apo3". Current Biology. 8 (9): 525–8. doi:10
Necroptosis (1,568 words) [view diff] exact match in snippet view article find links to article
receptor by TNFα signals the recruitment of the TNF receptor-associated death domain (TRADD) which in turn recruits RIPK1. In the absence of active Caspase
SUMO1 (2,314 words) [view diff] exact match in snippet view article find links to article
protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis". The Journal of Biological Chemistry. 274 (15):
Plasminogen activator inhibitor-1 (1,435 words) [view diff] exact match in snippet view article find links to article
bacterium • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • circadian rhythm • angiogenesis • positive regulation of
TMC8 (668 words) [view diff] exact match in snippet view article find links to article
oligomerization • regulation of extrinsic apoptotic signaling pathway via death domain receptors • zinc ion homeostasis • ion transport • negative regulation
Fibrinogen alpha chain (1,095 words) [view diff] exact match in snippet view article find links to article
pathway • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of vasoconstriction • positive regulation
NFKB1 (2,718 words) [view diff] exact match in snippet view article find links to article
COMPLEXED TO THE IMMUNOGLOBULIN KB DNA 2dbf: Solution structure of the Death domain in human Nuclear factor NF-kappa-B p105 subunit 2i9t: Structure of NF-kB
PEA15 (1,244 words) [view diff] exact match in snippet view article find links to article
pathway via death domain receptors • regulation of apoptotic process • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
Hepatocyte growth factor (2,645 words) [view diff] exact match in snippet view article find links to article
proliferation • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • animal organ regeneration • cell morphogenesis • positive
PYCARD (1,320 words) [view diff] exact match in snippet view article find links to article
(CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes
ABCA1 (2,081 words) [view diff] exact match in snippet view article find links to article
interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein". The Journal of Biological Chemistry. 277 (44): 41307–10. doi:10
Cytotoxic T cell (2,427 words) [view diff] exact match in snippet view article find links to article
recruitment of the death-induced signaling complex (DISC). The Fas-associated death domain (FADD) translocates with the DISC, allowing recruitment of procaspases
CNTRL (639 words) [view diff] exact match in snippet view article find links to article
monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling". J. Biol. Chem. 274 (15): 10203–12. doi:10.1074/jbc.274.15
STX4 (2,086 words) [view diff] exact match in snippet view article find links to article
cell surface • regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of insulin secretion involved in cellular
PSMD2 (3,541 words) [view diff] exact match in snippet view article find links to article
to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'". FEBS Lett. 367 (1): 39–44. doi:10.1016/0014-5793(95)00534-G. PMID 7601280
Neurofibromin 1 (5,984 words) [view diff] exact match in snippet view article find links to article
expression • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of neurotransmitter secretion • positive
Fibrinogen gamma chain (431 words) [view diff] exact match in snippet view article find links to article
spreading • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of vasoconstriction • positive regulation
Bone morphogenetic protein 5 (1,025 words) [view diff] exact match in snippet view article find links to article
development • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of insulin-like growth factor receptor
Reactive oxygen species (8,445 words) [view diff] exact match in snippet view article find links to article
necessary for subsequent recruitment of Fas-associated protein with death domain and caspase 8 as well as apoptosis induction. In the intrinsic pathway
Drosophila melanogaster (15,775 words) [view diff] exact match in snippet view article find links to article
activation of downstream NF-κB signaling pathways, including multiple death domain containing proteins and negative regulators such as the ankyrin repeat
Endothelial NOS (3,995 words) [view diff] exact match in snippet view article find links to article
remodeling • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • angiogenesis • negative regulation of potassium ion transport
Bcl-2 (4,655 words) [view diff] exact match in snippet view article find links to article
pathway in absence of ligand • extrinsic apoptotic signaling pathway via death domain receptors • response to drug • release of cytochrome c from mitochondria
THOC1 (867 words) [view diff] exact match in snippet view article find links to article
PMID 15302935. Gasparri F, Sola F, Locatelli G, Muzio M (2004). "The death domain protein p84N5, but not the short isoform p84N5s, is cell cycle-regulated
Thrombospondin 1 (2,104 words) [view diff] exact match in snippet view article find links to article
production • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of cysteine-type endopeptidase activity
MBD4 (2,208 words) [view diff] exact match in snippet view article find links to article
Maddison K, Bird A, Clarke AR, Frisch SM (Apr 2003). "Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: A potential
BH3 interacting-domain death agonist (1,246 words) [view diff] exact match in snippet view article find links to article
membrane permeabilization • extrinsic apoptotic signaling pathway via death domain receptors • hepatocyte apoptotic process • release of cytochrome c from
PDCD6 (1,225 words) [view diff] exact match in snippet view article find links to article
Kim J W; Kim E (October 2001). "Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat
DNA damage-inducible transcript 3 (5,471 words) [view diff] exact match in snippet view article find links to article
death receptors. Upon activation, the receptor protein, Fas-associated death domain protein, forms death-inducing signaling complex, which activates the
Bcl-2-associated X protein (2,112 words) [view diff] exact match in snippet view article find links to article
protein oligomerization • extrinsic apoptotic signaling pathway via death domain receptors • release of cytochrome c from mitochondria • apoptotic process
SIVA1 (990 words) [view diff] exact match in snippet view article find links to article
P, et al. (2004). "Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent
BLOC1S2 (558 words) [view diff] exact match in snippet view article find links to article
membrane permeabilization • extrinsic apoptotic signaling pathway via death domain receptors • microtubule nucleation • lysosome localization • endosomal
ANK2 (3,673 words) [view diff] exact match in snippet view article find links to article
a central region with a highly conserved spectrin binding domain and death domain; and a C-terminal regulatory domain which is the least conserved and
Telomerase reverse transcriptase (5,294 words) [view diff] case mismatch in snippet view article find links to article
apoptosis. Apoptotic death factors like FADD (Fas-Associated protein with Death Domain) can be used to force cells expressing hTERT to undergo apoptosis. Viral
Itoigawa Domain (1,434 words) [view diff] no match in snippet view article find links to article
Naoyoshi, and became daimyō at the age of eight upon his father's sudden death. Domain affairs were handled by Matsudaira Naokata, who also oversaw his genpuku
MOAP1 (606 words) [view diff] exact match in snippet view article find links to article
apoptotic signaling pathway • extrinsic apoptotic signaling pathway via death domain receptors • intrinsic apoptotic signaling pathway in response to DNA
Bcl-2-associated death promoter (1,975 words) [view diff] exact match in snippet view article find links to article
cellular response to chromate • extrinsic apoptotic signaling pathway via death domain receptors • response to drug • response to hydrogen peroxide • response
C-Raf (8,652 words) [view diff] exact match in snippet view article find links to article
assembly • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • intermediate filament cytoskeleton organization • regulation
TMBIM1 (603 words) [view diff] exact match in snippet view article find links to article
remodeling • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • GO:0048553 negative regulation of catalytic activity • neutrophil
HSPA8 (3,519 words) [view diff] exact match in snippet view article find links to article
"Tumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domain". Molecular and Cellular Biology. 22 (8): 2536–43. doi:10.1128/MCB.22
BRCA1 (14,067 words) [view diff] exact match in snippet view article find links to article
indole-3-methanol • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of transcription, DNA-templated • positive
RFFL (385 words) [view diff] exact match in snippet view article find links to article
apoptosis • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • protein ubiquitination • negative regulation of signal transduction
APBB2 (645 words) [view diff] exact match in snippet view article find links to article
et al. (2007). "Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-κB, JNK1
RIPK2 (962 words) [view diff] exact match in snippet view article find links to article
Yano H, et al. (2001). "A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein
DEDD (671 words) [view diff] exact match in snippet view article find links to article
process • spermatogenesis • extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of protein catabolic process • decidualization
TNFAIP8 (467 words) [view diff] exact match in snippet view article find links to article
the consensus sequence of a death effector domain of fas-associated death domain-like interleukin- 1beta-converting enzyme-inhibitory protein". J Biol
TNFSF12 (1,133 words) [view diff] no match in snippet view article find links to article
Goddard A, Ashkenazi A (April 1998). "Identification of a ligand for the death-domain-containing receptor Apo3". Current Biology. 8 (9): 525–8. doi:10
GPX1 (2,930 words) [view diff] exact match in snippet view article find links to article
development • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • biological process involved in interaction with symbiont
MAL (gene) (984 words) [view diff] exact match in snippet view article
process • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • central nervous system development • cell differentiation
NLRP1 (2,218 words) [view diff] exact match in snippet view article find links to article
Tschopp J (February 2001). "The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation". Current Biology
CASP8AP2 (830 words) [view diff] exact match in snippet view article find links to article
involved in apoptotic process • extrinsic apoptotic signaling pathway via death domain receptors • signal transduction • apoptotic process • negative regulation
SKIL (1,085 words) [view diff] exact match in snippet view article find links to article
process • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • response to cytokine • lymphocyte homeostasis • response
Anticancer gene (6,286 words) [view diff] exact match in snippet view article find links to article
include, but not limited to, DNA, clyclinA-CDK2, and fas-associated death domain protein (FADD).[citation needed] Current apoptin therapeutic agents have
NLRP2 (1,575 words) [view diff] exact match in snippet view article find links to article
Tschopp J (February 2001). "The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation". Current Biology
DDX3X (1,791 words) [view diff] exact match in snippet view article find links to article
regulation of translation • extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of transcription by RNA polymerase II
GABARAP (1,670 words) [view diff] exact match in snippet view article find links to article
cytoskeleton organization • extrinsic apoptotic signaling pathway via death domain receptors • apoptotic process • GO:0000046 autophagosome maturation •
Fibrinogen beta chain (958 words) [view diff] exact match in snippet view article find links to article
spreading • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of vasoconstriction • cellular response
TRA2B (1,016 words) [view diff] exact match in snippet view article find links to article
Dollé L, et al. (2003). "Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic
RNF34 (571 words) [view diff] exact match in snippet view article find links to article
mediator • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • nucleotide-binding domain, leucine rich repeat containing
FAF1 (927 words) [view diff] exact match in snippet view article find links to article
process • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of cell death • positive regulation of
Diablo homolog (2,423 words) [view diff] exact match in snippet view article find links to article
involved in apoptotic process • extrinsic apoptotic signaling pathway via death domain receptors • apoptotic process • activation of cysteine-type endopeptidase
Otodental syndrome (1,659 words) [view diff] exact match in snippet view article find links to article
with signs of ocular coloboma, a microdeletion in the Fas-associated death domain (FADD) gene (11q13.3) was also found to be responsible. There is variable
BCL2-like 1 (2,210 words) [view diff] exact match in snippet view article find links to article
process • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • growth • negative regulation of protein localization to plasma
TNFAIP3 (1,920 words) [view diff] exact match in snippet view article find links to article
pathway • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • protein complex oligomerization • protein K11-linked deubiquitination
Interleukin-1 receptor associated kinase (3,628 words) [view diff] case mismatch in snippet view article find links to article
members are multidomain proteins consisting of a conserved N-terminal Death Domain (DD) and a central kinase domain (KD). The DD is a protein interaction
PIK3R1 (2,992 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway • extrinsic apoptotic signaling pathway via death domain receptors • phosphatidylinositol-mediated signaling • leukocyte migration
ARHGEF2 (1,134 words) [view diff] exact match in snippet view article find links to article
activity • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • cell morphogenesis • establishment of mitotic spindle orientation
DAB2IP (861 words) [view diff] exact match in snippet view article find links to article
epithelial cell migration • extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of epithelial to mesenchymal transition
Phorbol-12-myristate-13-acetate-induced protein 1 (1,208 words) [view diff] exact match in snippet view article find links to article
process • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • response to dsRNA • cellular response to glucose starvation
DDX47 (741 words) [view diff] exact match in snippet view article find links to article
process • mRNA processing • extrinsic apoptotic signaling pathway via death domain receptors • RNA secondary structure unwinding • RNA splicing • apoptotic
Galectin-3 (2,819 words) [view diff] exact match in snippet view article find links to article
differentiation • regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of T cell activation via T cell receptor
NGFRAP1 (835 words) [view diff] exact match in snippet view article find links to article
involved in apoptotic process • extrinsic apoptotic signaling pathway via death domain receptors • apoptotic process • negative regulation of cysteine-type
SFRP2 (1,122 words) [view diff] exact match in snippet view article find links to article
division • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of cell growth • neural tube development
STK3 (1,828 words) [view diff] exact match in snippet view article find links to article
development • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of protein kinase B signaling • GO:0007243
RIG-I-like receptor (3,009 words) [view diff] case mismatch in snippet view article find links to article
Journal of Virology. 88 (14): 8180–8. doi:10.1128/jvi.00737-14. PMC 4097766. PMID 24829334. PTHR14074: Helicase with Death Domain-Related (filter for human)
David Wallach (855 words) [view diff] exact match in snippet view article find links to article
NEMO (IKK-γ). Wallach’s work has contributed to the discovery of the ‘death domain’ protein motif, and provided the first evidence that proteases can serve
BAG3 (3,584 words) [view diff] exact match in snippet view article find links to article
cellular response to heat • extrinsic apoptotic signaling pathway via death domain receptors • apoptotic process • GO:0048552 regulation of catalytic activity
Sortilin 1 (3,268 words) [view diff] exact match in snippet view article find links to article
neuropeptide signaling pathway • extrinsic apoptotic signaling pathway via death domain receptors • nerve growth factor signaling pathway • post-Golgi vesicle-mediated
Imd pathway (1,878 words) [view diff] exact match in snippet view article find links to article
in the gut. The principle intracellular signalling protein is Imd, a death domain-containing protein that binds with FADD and Dredd to form a complex.
Louis Tartaglia (1,583 words) [view diff] case mismatch in snippet view article find links to article
papers on TNF (Tumour necrosis factor) receptors, coining the term “Death Domain” to refer to the signaling of programmed cell death; homologous domains
Secreted frizzled-related protein 1 (6,294 words) [view diff] exact match in snippet view article find links to article
assembly • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of planar cell polarity pathway involved
Protein acetylation (4,894 words) [view diff] exact match in snippet view article find links to article
adaptor protein RIP associated Ich-1/Ced-3 homologous protein with a death domain (RAIDD). This could activate caspase-2 and induce cell apoptosis. Ribosome