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searching for DNMT3B 21 found (51 total)

alternate case: dNMT3B

GLAD-PCR assay (628 words) [view diff] case mismatch in snippet view article find links to article

unmethylated DNA at all. Mammalian DNA-methyltransferases DNMT1, DNMT3a and DNMT3b catalyze a reaction of DNA methylation. DNMT1 maintains DNA methylation

5-Methylcytosine (2,598 words) [view diff] exact match in snippet view article find links to article

methyltransferases (DNMTs). There are 5 DNMTs in humans: DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L, and in algae and fungi 3 more are present (DNMT4, DNMT5, and

Mir-720 microRNA precursor family (696 words) [view diff] case mismatch in snippet view article find links to article

stem cells required miR-720 that repressed Nanog and induced Dnmt3a and Dnmt3b. MicroRNA Gu H, Li H, Zhang L, Luan H, Huang T, Wang L, et al. (2012). "Diagnostic

DNMT3L (1,119 words) [view diff] case mismatch in snippet view article find links to article

S (2004). "DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction". J. Biol. Chem. 279 (26): 27816–23. doi:10

SMARCA5 (1,266 words) [view diff] exact match in snippet view article find links to article

TM, Sankpal UT, Robertson AK, Zhao Y, Zhao Y, Robertson KD (May 2004). "DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components

DNA methylation in cancer (3,792 words) [view diff] exact match in snippet view article find links to article

miRNAs miR-29a, miR-29b and miR-29c target DNMT3A and DNMT3B; miR-148a and miR-148b target DNMT3B; and miR-152 and miR-301 target DNMT1. In addition, miR-34b

Transcription (biology) (6,780 words) [view diff] exact match in snippet view article

DNMT3A, and DNMT3B) catalyze the addition of methyl groups to cytosines in DNA. While DNMT1 is a maintenance methyltransferase, DNMT3A and DNMT3B can carry

SMC4 (1,452 words) [view diff] exact match in snippet view article find links to article

"Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic

Transcriptional regulation (6,343 words) [view diff] exact match in snippet view article find links to article

DNMT3A, and DNMT3B) catalyze the addition of methyl groups to cytosines in DNA. While DNMT1 is a “maintenance” methyltransferase, DNMT3A and DNMT3B can carry

Placenta (4,636 words) [view diff] exact match in snippet view article find links to article

DNA methylation in placental development reveals an essential role for DNMT3B. Nat Commun. 2023 Jan 23;14(1):371. doi: 10.1038/s41467-023-36019-9. PMID:

ZHX1 (882 words) [view diff] exact match in snippet view article find links to article

and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression". Biochemical and Biophysical Research

Dirk Schübeler (758 words) [view diff] exact match in snippet view article find links to article

D (2015) Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation. Nature 520:243-8 Baubec T, Ivanek R, Lienert F, Schübeler

Interleukin 6 (7,425 words) [view diff] exact match in snippet view article find links to article

it can be transcribed. DNMT1 recruits other DNMTs, including DNMT3A and DNMT3B, which, as a complex, recruit HDAC1. This complex adds methyl groups to

Alternative splicing (8,375 words) [view diff] exact match in snippet view article find links to article

modification that often has regulatory effects. Several abnormally spliced DNMT3B mRNAs are found in tumors and cancer cell lines. In two separate studies

Epigenetic regulation of neurogenesis (5,725 words) [view diff] case mismatch in snippet view article find links to article

corticogenesis has been shown through knockout experiments in mice. When DNMT3b and DNMT1 were ablated separately in mouse embryos they died due to impairment

XIST (4,229 words) [view diff] exact match in snippet view article find links to article

Soukoyan M, Pereira LV (2007). "XIST repression in the absence of DNMT1 and DNMT3B". DNA Research. 12 (5): 373–8. doi:10.1093/dnares/dsi013. PMID 16769694

DNA repair (15,715 words) [view diff] case mismatch in snippet view article find links to article

found that polymerase beta recruited the DNA methyltransferase protein DNMT3b to BER repair sites. They then evaluated the methylation pattern at the

Sunit Kumar Singh (1,539 words) [view diff] case mismatch in snippet view article find links to article

(June 2023). "Zika virus NS1 suppresses VE-cadherin via hsa-miR-29b-3p/DNMT3b/MMP-9 pathway in human brain microvascular endothelial cells". Cellular

Lee Byung-heon (biochemist) (2,910 words) [view diff] exact match in snippet view article

Park, R. W.; Kim, I. S.; Cho, Y. L.; Jung, T. H.; Park, J. Y. (2004). "DNMT3B polymorphisms and risk of primary lung cancer". Carcinogenesis. 26 (2):

Epigenetics of physical exercise (8,910 words) [view diff] case mismatch in snippet view article find links to article

expression of the gene-repressive DNA methylating enzymes DNMT1, DNMT3a and DNMT3b. The hippocampus has important functions in memory, spatial navigation and

Epigenetics of neurodegenerative diseases (13,392 words) [view diff] exact match in snippet view article find links to article

points to upregulation of the DNA methyltransferase genes DNMT1, DNMT3A, and DNMT3B in patients with myasthenia gravis. In addition to CTLA-4 methylation, hypermethylation