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searching for DNA demethylation 63 found (105 total)

alternate case: dNA demethylation

Alkb homolog 1, histone h2a dioxygenase (583 words) [view diff] exact match in snippet view article find links to article

demethylation developmental growth regulation of gene expression RNA repair DNA demethylation positive chemotaxis metabolism neuron projection development DNA repair
Tet methylcytosine dioxygenase 3 (1,558 words) [view diff] exact match in snippet view article find links to article
(ten-eleven-translocation) family of genes and proteins that play a role in DNA demethylation. DNA demethylation is the removal of suppressive methyl groups from the cytosine
DPPA3 (420 words) [view diff] exact match in snippet view article find links to article
Arai Y, Umehara H, et al. (2007). "PGC7/Stella protects against DNA demethylation in early embryogenesis". Nat. Cell Biol. 9 (1): 64–71. doi:10.1038/ncb1519
Jian-Kang Zhu (2,365 words) [view diff] exact match in snippet view article find links to article
active DNA demethylation) established with genetic and biochemical evidence. It initiates a base-excision repair pathway for active DNA demethylation to erase
Epigenome editing (3,068 words) [view diff] exact match in snippet view article find links to article
well. Maeder et al. has constructed a ZF-TET1 protein for use in DNA demethylation. These zinc finger proteins work similarly to TALE proteins in that
5-Methylcytosine (2,621 words) [view diff] exact match in snippet view article find links to article
Passive DNA demethylation by dilution eliminates the mark gradually through replication by a lack of maintenance by DNMT. In active DNA demethylation, a series
Thymine-DNA glycosylase (1,599 words) [view diff] exact match in snippet view article find links to article
embryo development negative regulation of chromatin binding oxidative DNA demethylation negative regulation of transcription by RNA polymerase II negative
Activation-induced cytidine deaminase (2,466 words) [view diff] exact match in snippet view article find links to article
super-enhancer activity. Recently, AICDA has been implicated in active DNA demethylation. AICDA can deaminate 5-methylcytosine, which can then be replaced
Germline (1,893 words) [view diff] exact match in snippet view article find links to article
genome-wide DNA demethylation, followed by subsequent new methylation to reset the epigenome in order to form an egg or sperm. In the mouse, PGCs undergo DNA demethylation
Demethylation (1,390 words) [view diff] exact match in snippet view article find links to article
RM, Zhang Y (October 2013). "TET enzymes, TDG and the dynamics of DNA demethylation". Nature. 502 (7472): 472–9. Bibcode:2013Natur.502..472K. doi:10.1038/nature12750
FTO gene (4,353 words) [view diff] exact match in snippet view article find links to article
development DNA demethylation regulation of brown fat cell differentiation temperature homeostasis oxidative single-stranded DNA demethylation DNA repair
APOBEC2 (557 words) [view diff] exact match in snippet view article find links to article
protein binding Cellular component nucleus cytoplasm Biological process DNA demethylation mRNA processing mRNA modification cytidine deamination cytidine to
Elisabeth Binder (667 words) [view diff] exact match in snippet view article find links to article
; Rein, Theo; Binder, Elisabeth B. (2013). "Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions". Nature Neuroscience
APOBEC3D (593 words) [view diff] exact match in snippet view article find links to article
via double stranded DNA intermediate immune system process cytidine deamination cytidine to uridine editing DNA demethylation Sources:Amigo / QuickGO
OTUD4 (646 words) [view diff] exact match in snippet view article find links to article
response protein K63-linked deubiquitination positive regulation of DNA demethylation regulation of protein K48-linked deubiquitination negative regulation
FEZF1 (611 words) [view diff] exact match in snippet view article find links to article
oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer". International Journal
Institute of Molecular Biology (450 words) [view diff] case mismatch in snippet view article find links to article
Ketting) Modelling Biological Regulatory Networks (Stefan Legewie) DNA Demethylation, DNA Repair and Reprogramming (Christof Niehrs) Gene Expression, Transcriptional
XAF1 (1,045 words) [view diff] exact match in snippet view article find links to article
interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation". J. Clin. Oncol. 24 (23): 3771–9. CiteSeerX 10.1.1.1025.9291. doi:10
Neuroimmunology (2,716 words) [view diff] exact match in snippet view article find links to article
that have a broad set of biochemical modifications and can affect DNA demethylation and synergy with other therapeutic agents. The final therapy includes
Transgenerational epigenetic inheritance in plants (2,184 words) [view diff] exact match in snippet view article find links to article
methyl groups from DNA. Plants are unique in their use of active DNA demethylation. They use the Base Excision Repair (BER) pathway to remove methylated
Scientific misconduct (5,811 words) [view diff] exact match in snippet view article find links to article
H.; Takeyama, K. I.; Shibuya, H.; Ohtake, F.; Kato, S. (2009). "DNA demethylation in hormone-induced transcriptional derepression". Nature. 461 (7266):
Human epigenome (2,664 words) [view diff] exact match in snippet view article find links to article
experiments that in human preimplantation embryos there is a global DNA demethylation process. After fertilisation, the DNA methylation level decreases
APOBEC3H (952 words) [view diff] exact match in snippet view article find links to article
via double stranded DNA intermediate immune system process cytidine deamination cytidine to uridine editing DNA demethylation Sources:Amigo / QuickGO
USP9X (1,504 words) [view diff] exact match in snippet view article find links to article
deubiquitination protein deubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of DNA demethylation Sources:Amigo / QuickGO
APOBEC3F (934 words) [view diff] exact match in snippet view article find links to article
genome replication defense response to virus DNA cytosine deamination DNA demethylation innate immune response negative regulation of single stranded viral
APOBEC3B (927 words) [view diff] exact match in snippet view article find links to article
immune response immune system process defense response to virus cytidine deamination cytidine to uridine editing DNA demethylation Sources:Amigo / QuickGO
John Gurdon (1,841 words) [view diff] exact match in snippet view article find links to article
144. PMC 3116279. PMID 21552206. Simonsson, S.; Gurdon, J. (2004). "DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei"
Marisa Bartolomei (820 words) [view diff] exact match in snippet view article find links to article
(8 July 2011). "Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair". Cell. 146 (1): 67–79
FACT (biology) (641 words) [view diff] exact match in snippet view article
Tetsu; Choi, Yeonhee (2018-05-15). "FACT complex is required for DNA demethylation at heterochromatin during reproduction in Arabidopsis". Proceedings
TRIM28 (2,246 words) [view diff] exact match in snippet view article find links to article
polymerase II transcription, DNA-templated negative regulation of DNA demethylation protein phosphorylation protein complex oligomerization protein autophosphorylation
Epigenetics of anxiety and stress–related disorders (8,473 words) [view diff] exact match in snippet view article find links to article
5-hydroxymethylcytosine (5hmC) within the genome. This reaction initiates active DNA demethylation to ultimately alter gene expression. It has been found that the TET
Germline development (4,011 words) [view diff] exact match in snippet view article find links to article
and Prdm14 also elicit another epigenetic event that causes global DNA demethylation. Other notable genes positively regulated by Blimp1 and Prdm14 are:
DNA methyltransferase (3,569 words) [view diff] case mismatch in snippet view article find links to article
PMID 35098021. Bayraktar G, Kreutz MR (2018). "The Role of Activity-Dependent DNA Demethylation in the Adult Brain and in Neurological Disorders". Front Mol Neurosci
Yi Zhang (biochemist) (2,624 words) [view diff] exact match in snippet view article
5-carboxylcytosine (5caC) in mammalian genomic DNA, but also elucidated the DNA demethylation mechanism by demonstrating that Tet proteins can sequentially oxidize
Alkb homolog 3, alpha-ketoglutaratedependent dioxygenase (613 words) [view diff] exact match in snippet view article find links to article
DNA dealkylation involved in DNA repair oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation DNA repair Sources:Amigo
RNA-directed DNA methylation (14,790 words) [view diff] exact match in snippet view article find links to article
spreading, DNA methylation pathways are opposed by passive and active DNA demethylation. DNA methylation can be lost passively with each cell division, because
DNA glycosylase (4,014 words) [view diff] exact match in snippet view article find links to article
(2006). "Role of the Arabidopsis DNA glycosylase/lyase ROS1 in active DNA demethylation". Proc. Natl. Acad. Sci. U.S.A. 103 (31): 11796–11801. Bibcode:2006PNAS
5-Formylcytosine (915 words) [view diff] exact match in snippet view article find links to article
Retrieved 2020-07-26. Wu, Xiaoji; Zhang, Yi (2017). "TET-mediated active DNA demethylation: mechanism, function and beyond". Nature Reviews Genetics. 18 (9):
Protein arginine methyltransferase 5 (2,032 words) [view diff] case mismatch in snippet view article find links to article
Surani MA (Nov 2014). "PRMT5 Protects Genomic Integrity during Global DNA Demethylation in Primordial Germ Cells and Preimplantation Embryos". Molecular Cell
APEX1 (1,317 words) [view diff] exact match in snippet view article find links to article
muscle cell migration regulation of transcription, DNA-templated DNA demethylation cellular response to cAMP RNA phosphodiester bond hydrolysis, endonucleolytic
Charles Brenner (2,149 words) [view diff] case mismatch in snippet view article find links to article
PMID 23839987. Wu, B-K; Brenner, C (2014). "Suppression of TET1-Dependent DNA Demethylation Is Essential for KRAS-Mediated Transformation". Cell Reports. 9 (5):
APOBEC3C (1,887 words) [view diff] exact match in snippet view article find links to article
response GO:0022415 viral process negative regulation of transposition DNA demethylation cytidine to uridine editing negative regulation of single stranded
GATA3 (3,739 words) [view diff] exact match in snippet view article find links to article
differentiation parathyroid gland development negative regulation of DNA demethylation positive regulation of interleukin-4 production negative regulation
Carolyn J. Brown (1,354 words) [view diff] exact match in snippet view article find links to article
human active X chromosome in mouse/human somatic cell hybrids by DNA demethylation". Nucleic Acids Research. 26 (12): 2935–40. doi:10.1093/nar/26.12
USP7 (2,062 words) [view diff] exact match in snippet view article find links to article
process protein K48-linked deubiquitination positive regulation of DNA demethylation regulation of circadian rhythm rhythmic process Sources:Amigo / QuickGO
Regulation of gene expression (5,213 words) [view diff] exact match in snippet view article find links to article
BE, Costello JF, Wilkinson MF, Joung JK (December 2013). "Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion
Alpha-ketoglutarate-dependent hydroxylases (3,981 words) [view diff] exact match in snippet view article find links to article
protein hydroxylation), epigenetic regulations (e.g. histone and DNA demethylation), as well as sensors of energy metabolism. Many αKG-dependent dioxygenase
APOBEC3G (2,937 words) [view diff] exact match in snippet view article find links to article
process defense response to virus innate immune response GO:0022415 viral process cytidine to uridine editing DNA demethylation Sources:Amigo / QuickGO
Tumor necrosis factor (5,015 words) [view diff] exact match in snippet view article find links to article
et al. (April 2019). "The proinflammatory cytokine TNFα induces DNA demethylation-dependent and -independent activation of interleukin-32 expression"
APOBEC3A (1,680 words) [view diff] exact match in snippet view article find links to article
response to xenobiotic stimulus negative regulation of transposition DNA demethylation negative regulation of viral genome replication innate immune response
APOBEC1 (2,775 words) [view diff] exact match in snippet view article find links to article
to uridine editing response to gamma radiation mRNA stabilization DNA demethylation lipoprotein metabolic process lipoprotein transport GO:0048554 positive
Lamarckism (10,489 words) [view diff] case mismatch in snippet view article find links to article
Sengupta, Roopsha; Zylicz, Jan J.; et al. (January 25, 2013). "Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine". Science
TCF21 (gene) (3,600 words) [view diff] exact match in snippet view article
antisense orientation to TCF21. TARID then induces TET protein-dependent DNA demethylation, thus activating TCF21 transcription. This mechanism is regulated
Transgenerational epigenetic inheritance (8,122 words) [view diff] exact match in snippet view article find links to article
Murakami K, Lee C, Down TA, Surani MA (January 2013). "Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine". Science
George Church (geneticist) (5,391 words) [view diff] exact match in snippet view article
reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites
Epigenetics of autoimmune disorders (5,683 words) [view diff] exact match in snippet view article find links to article
that contains a high percentage of cytosine and guanine nucleotides. DNA demethylation is carried out by Ten-Eleven Translocation (TET) enzymes which convert
Farah Lubin (2,454 words) [view diff] exact match in snippet view article find links to article
Pacheco NL, Lubin FD. 2015. NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation. Frontiers in Molecular
Long non-coding RNA (12,140 words) [view diff] exact match in snippet view article find links to article
modulating pluripotency-specific chromosomal looping and TET2-mediated DNA demethylation". Nucleic Acids Research. 48 (7): 3935–3948. doi:10.1093/nar/gkaa097
Reelin (15,619 words) [view diff] exact match in snippet view article find links to article
"Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation". Proceedings of the National Academy of Sciences of the United States
George Tsokos (3,377 words) [view diff] exact match in snippet view article find links to article
S, Sharabi A, Li Y, Moulton VR, et al. (August 2018). "Precision DNA demethylation ameliorates disease in lupus-prone mice". JCI Insight. 3 (16): e120880
Epigenetics of physical exercise (7,042 words) [view diff] case mismatch in snippet view article find links to article
Bayraktar G, Kreutz MR (2018-05-23). "The Role of Activity-Dependent DNA Demethylation in the Adult Brain and in Neurological Disorders". Frontiers in Molecular
Mature T-cell lymphoma (3,083 words) [view diff] exact match in snippet view article find links to article
M.; Zhang, Yi (2013-10-24). "TET enzymes, TDG and the dynamics of DNA demethylation". Nature. 502 (7472): 472–479. Bibcode:2013Natur.502..472K. doi:10
Induced stem cells (24,741 words) [view diff] exact match in snippet view article find links to article
pluripotent state. The basis for this approach was that 5-azacytidine – a DNA demethylation reagent – can cause the formation of myogenic, chondrogenic, and adipogeni