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Longer titles found: Cytochrome P450 BM3 (view), Cytochrome P450 aromatic O-demethylase (view), Cytochrome P450 engineering (view), Cytochrome P450 eryF (view), Cytochrome P450 omega hydroxylase (view), Cytochrome P450 oxidoreductase deficiency (view), Cytochrome P450 reductase (view), List of cytochrome P450 modulators (view), Cytochrome p450 family 19 subfamily a member 1 (view)

searching for Cytochrome P450 128 found (1266 total)

alternate case: cytochrome P450

3-Epi-6-deoxocathasterone 23-monooxygenase (160 words) [view diff] exact match in snippet view article find links to article

3-Epi-6-deoxocathasterone 23-monooxygenase (EC 1.14.13.112, cytochrome P450 90C1, CYP90D1, CYP90C1) is an enzyme with systematic name 3-epi-6-deoxocathasterone
Econazole (393 words) [view diff] no match in snippet view article find links to article
Econazole is an antifungal medication of the imidazole class. It was patented in 1968, and approved for medical use in 1974. Econazole is used as a cream
Methoxsalen (696 words) [view diff] no match in snippet view article find links to article
Methoxsalen, sold under the brand name Oxsoralen among others, is a medication used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas
Miconazole (1,086 words) [view diff] exact match in snippet view article find links to article
Formulary '45' March 2003 Becher R, Wirsel SG (August 2012). "Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human
Aldehyde oxidase (887 words) [view diff] exact match in snippet view article find links to article
hydroxylation of some heterocycles. It can also catalyze the oxidation of both cytochrome P450 (CYP450) and monoamine oxidase (MAO) intermediate products. AO plays
Xanthonoid (488 words) [view diff] exact match in snippet view article find links to article
intermediate is subsequently converted by a benzophenone 3′-hydroxylase, a cytochrome P450 monooxygenase, leading to the formation of 2,3′,4,6-tetrahydroxybenzophenone
6-Hydroxyflavone (143 words) [view diff] exact match in snippet view article find links to article
of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in Crocus and leaves of Barleria prionitis Linn
(+)-Menthofuran synthase (166 words) [view diff] exact match in snippet view article
13.104, menthofuran synthase, (+)-pulegone 9-hydroxylase, (+)-MFS, cytochrome P450 menthofuran synthase) is an enzyme with systematic name (+)-pulegone
Benzoyl-CoA (196 words) [view diff] exact match in snippet view article find links to article
intermediate is subsequently converted by a benzophenone 3′-hydroxylase, a cytochrome P450 monooxygenase, leading to the formation of 2,3′,4,6-tetrahydroxybenzophenone
Molecular Discovery (301 words) [view diff] exact match in snippet view article find links to article
well as pKa and tautomer modelling. Molecular Discovery manages a Cytochrome P450 Consortium aimed at generating a large set of homogeneous experimental
Irinotecan (2,121 words) [view diff] exact match in snippet view article find links to article
re-circulation of SN-38. Irinotecan is metabolized by intrahepatic cytochrome P450 enzymes, CYP3A4 and CYP3A5 into inactive metabolites APC
Kavalactone (798 words) [view diff] exact match in snippet view article find links to article
Mathews; Amy S. Etheridge; Sherry R. Black (2002). "Inhibition of Human Cytochrome P450 Activities by Kava Extract and Kavalactones". Drug Metabolism and Disposition
Lithocholate 6beta-hydroxylase (280 words) [view diff] exact match in snippet view article find links to article
lithocholate 6beta-monooxygenase, CYP3A10, 6beta-hydroxylase, and cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase. Teixeira J, Gil G (1991).
Salvestrol (188 words) [view diff] exact match in snippet view article find links to article
"Nutrition and the Prevention and Treatment of Cancer: Association of Cytochrome P450 CYP1B1 With the Role of Fruit and Fruit Extracts". Integrative Cancer
Aldehyde dehydrogenase (NAD(P)+) (268 words) [view diff] case mismatch in snippet view article
metabolism, phenylalanine metabolism, and metabolism of xenobiotics by cytochrome p450. As of late 2007, 4 structures have been solved for this class of enzymes
Grapefruit–drug interactions (5,734 words) [view diff] exact match in snippet view article find links to article
flavonoids). These chemicals inhibit key drug metabolizing enzymes, such as cytochrome P450 3A4 (CYP3A4). CYP3A4 is a metabolizing enzyme for almost 50% of drugs
Cycloleucine (453 words) [view diff] exact match in snippet view article find links to article
pathway. Cycloleucine treatment in conjunction with higher levels of cytochrome P450 2E1 (CYP2E1) and lower SAM levels in pyrazole hepatocytes had shown
Unspecific monooxygenase (908 words) [view diff] case mismatch in snippet view article find links to article
metabolism, linoleic acid metabolism, and metabolism of xenobiotics by cytochrome p450. It employs one cofactor, heme. As of late 2007, 53 structures have
Cycloleucine (453 words) [view diff] exact match in snippet view article find links to article
pathway. Cycloleucine treatment in conjunction with higher levels of cytochrome P450 2E1 (CYP2E1) and lower SAM levels in pyrazole hepatocytes had shown
Anthoceros agrestis (487 words) [view diff] exact match in snippet view article find links to article
11), a cytochrome P450-dependent hydroxylase. Cinnamic acid 4-hydroxylase (C4H; EC 1.14.13.11) is one of the first known plant cytochrome P450 monooxygenases
Tyrosine N-monooxygenase (447 words) [view diff] exact match in snippet view article find links to article
and Arabidopsis plants expressing the two multifunctional sorghum cytochrome P450 enzymes, CYP79A1 and CYP71E1, are cyanogenic and accumulate metabolites
Cholestanetriol 26-monooxygenase (463 words) [view diff] exact match in snippet view article find links to article
sterol 26-hydroxylase, cholesterol 27-hydroxylase, CYP27A, CYP27A1, and cytochrome P450 27A1'. This enzyme participates in bile acid biosynthesis and ppar
Menthofuran (412 words) [view diff] exact match in snippet view article find links to article
Murphy SE (May 2012). "Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol". Chemico-Biological
4-hydroxyphenylacetaldehyde oxime monooxygenase (325 words) [view diff] exact match in snippet view article find links to article
oxime monooxygenase, cytochrome P450II-dependent monooxygenase, NADPH-cytochrome P450 reductase (CYP71E1), CYP71E1, and 4-hydroxyphenylacetaldehyde oxime
Methysticin (295 words) [view diff] exact match in snippet view article find links to article
exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation". Molecular Pharmacology
Active metabolite (424 words) [view diff] exact match in snippet view article find links to article
inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development". Current Medicinal Chemistry
6β-Hydroxycortisol (358 words) [view diff] case mismatch in snippet view article find links to article
endogenous steroid. In humans, it is a metabolite of cortisol produced by cytochrome p450-3A monooxygenases, mainly, CYP3A4. 6β-hydroxycortisol is used as a
Quercetin (2,473 words) [view diff] exact match in snippet view article find links to article
In-vitro studies show that quercetin is a strong inhibitor of the cytochrome P450 enzymes CYP3A4 and CYP2C19 and a moderate inhibitor of CYP2D6. Drugs
Nicotyrine (419 words) [view diff] exact match in snippet view article find links to article
Murphy SE (May 2012). "Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol". Chemico-Biological
Avacopan (789 words) [view diff] exact match in snippet view article find links to article
Administration (FDA). Avacopan is a complement 5a receptor antagonist and a cytochrome P450 3A4 (CYP3A4) inhibitor. In the United States, avacopan is indicated
Ethylmorphine (377 words) [view diff] exact match in snippet view article find links to article
(January 1998). "Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes". Toxicology Letters. 94 (2):
Bufuralol (102 words) [view diff] exact match in snippet view article find links to article
PMC 1401192. PMID 2878678. Flockhart DA (2007). "Drug Interactions: Cytochrome P450 Drug Interaction Table". Indiana University School of Medicine. Retrieved
Pisatin (1,366 words) [view diff] exact match in snippet view article find links to article
for this catalysis and has been identified in N. haematococca as a cytochrome P450 enzyme. Most fungi capable of this metabolism are resistant to pisatin
1,8-Cineole 2-exo-monooxygenase (192 words) [view diff] exact match in snippet view article find links to article
monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes". Drug Metabolism and
Abietadiene hydroxylase (169 words) [view diff] exact match in snippet view article find links to article
"Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in
TPA-023 (625 words) [view diff] exact match in snippet view article find links to article
Polsky-Fisher SL, Vickers S, Cui D, Rodrigues AD (August 2007). "Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric
Carotene epsilon-monooxygenase (171 words) [view diff] case mismatch in snippet view article find links to article
(January 2004). "The Arabidopsis LUT1 locus encodes a member of the cytochrome p450 family that is required for carotenoid epsilon-ring hydroxylation activity"
Gene silencing pesticide (268 words) [view diff] exact match in snippet view article find links to article
led by Xiao-Ya Chen fed gossypol with dsRNA targeting the gene for cytochrome P450 to bollworm larvae to kill them off Devgen has developed a gene silencing
Albendazole monooxygenase (198 words) [view diff] exact match in snippet view article find links to article
albendazole sulfoxidase. It employs one cofactor, FAD. "Showing Protein Cytochrome P450 3A4 (HMDBP01018)". Human Metabolome Database. Retrieved 2017-08-05
Zileuton (1,269 words) [view diff] exact match in snippet view article find links to article
for the next largest amount (~2%). The drug is metabolized by the cytochrome P450 enzymes: CYP1A2, 2C9, and 3A4. The most common adverse reactions reported
Abieta-7,13-dien-18-al dehydrogenase (183 words) [view diff] exact match in snippet view article find links to article
"Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in
Cytochrome b5, type A (903 words) [view diff] exact match in snippet view article find links to article
ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems"
4-EA-NBOMe (232 words) [view diff] exact match in snippet view article find links to article
S2CID 206923339. Caspar AT, Meyer MR, Maurer HH (March 2018). "Human cytochrome P450 kinetic studies on six N-2-methoxybenzyl (NBOMe)-derived new psychoactive
Biliverdin reductase B (1,052 words) [view diff] exact match in snippet view article find links to article
heme oxygenase-1 (hHO-1) in conjunction with cytochrome p450 reductase to catalyzes the NADPH-cytochrome P450 reductase-dependent oxidation of heme to biliverdin
PGRMC1 (1,960 words) [view diff] exact match in snippet view article find links to article
Link AJ, Espenshade PJ (Feb 2007). "Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes". Cell Metabolism. 5 (2): 143–9. doi:10.1016/j.cmet.2006.12
Streptomyces bungoensis (312 words) [view diff] exact match in snippet view article find links to article
pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene". Journal of Bioscience and Bioengineering. 105 (6): 649–654.
Streptomyces bungoensis (312 words) [view diff] exact match in snippet view article find links to article
pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene". Journal of Bioscience and Bioengineering. 105 (6): 649–654.
Benzopyrene (614 words) [view diff] exact match in snippet view article find links to article
modification has been investigated extensively and relates to the activity of cytochrome P450 subclass 1A1 (CYP1A1). Seemingly, the high activity of CYP1A1 in the
Licodione synthase (209 words) [view diff] exact match in snippet view article find links to article
Otani K, Takahashi T, Furuya T, Ayabe S (1994). "Licodione Synthase, a Cytochrome P450 Monooxygenase Catalyzing 2-Hydroxylation of 5-Deoxyflavanone, in Cultured
Phenylalanine N-monooxygenase (163 words) [view diff] exact match in snippet view article find links to article
heme-thiolate protein (P-450). Wittstock U, Halkier BA (May 2000). "Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. Catalyzes the conversion of L-phenylalanine
Quinine 3-monooxygenase (304 words) [view diff] exact match in snippet view article find links to article
Relling MV, Evans R, Dass C, Desiderio DM, Nemec J (1992). "Human cytochrome P450 metabolism of teniposide and etoposide". J. Pharmacol. Exp. Ther. 261
Fucophlorethol A (77 words) [view diff] exact match in snippet view article find links to article
vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 enzymes. Sabine Parys, Stefan Kehraus, Anja Krick, Karl-Werner Glombitza
Azamulin (170 words) [view diff] exact match in snippet view article find links to article
Kishnani NS, Alton KB (December 2007). "Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor
Rivastigmine (1,419 words) [view diff] exact match in snippet view article find links to article
hydrolysis. Elimination bypasses the hepatic system, so hepatic cytochrome P450 (CYP) isoenzymes are not involved. The low potential for drug-drug
AHRR (47 words) [view diff] exact match in snippet view article find links to article
AHRR may refer to: Aryl hydrocarbon receptor repressor, gene Cytochrome P450, family 1, member A1, enzyme This disambiguation page lists articles associated
Drosophila nigrospiracula (1,648 words) [view diff] case mismatch in snippet view article find links to article
without the proper allelochemical detoxification enzymes – namely the cytochrome p450 system. In general, formation of plant decay can come from injury or
Banpeiyu (453 words) [view diff] exact match in snippet view article find links to article
Seen" at Jeffrey Friedl's Blog "Inhibitory effects of citrus fruits on cytochrome P450 3A (CYP3A) activity in humans" "Production of Haploid Plant of 'Banpeiyu'
Synergistic enhancer (antiretroviral) (686 words) [view diff] exact match in snippet view article
a common natural plant extract. The enzyme CYP3A4, a member of the Cytochrome P450 enzyme family, is present mostly in the liver but also in the lining
Tryptophan N-monooxygenase (318 words) [view diff] exact match in snippet view article find links to article
Mikkelsen MD, Hansen CH, Wittstock U, Halkier BA (October 2000). "Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to
Grape seed extract (581 words) [view diff] exact match in snippet view article find links to article
PMID 29651231. Wanwimolruk, S; Phopin, K; Prachayasittikul, V (2014). "Cytochrome P450 enzyme mediated herbal drug interactions (Part 2)". EXCLI Journal.
Bifluranol (690 words) [view diff] exact match in snippet view article find links to article
C (October 1998). "Inhibitors of enzymes of androgen biosynthesis: cytochrome P450(17) alpha and 5 alpha-steroid reductase". Natural Product Reports.
Taxane 10beta-hydroxylase (254 words) [view diff] exact match in snippet view article find links to article
differential transformations of taxadien-5 alpha-ol and its acetate ester by cytochrome P450 hydroxylases from Taxus suspension cells". Arch. Biochem. Biophys.
Cortisol (6,951 words) [view diff] case mismatch in snippet view article find links to article
Cortisol is also metabolized irreversibly into 6β-hydroxycortisol by cytochrome p450-3A monooxygenases, mainly, CYP3A4. Drugs that induce CYP3A4 may accelerate
Chromosome 8 (1,887 words) [view diff] exact match in snippet view article find links to article
helix repeat containing 1 CYP11B1: cytochrome P450, family 11, subfamily B, polypeptide 1 CYP11B2: cytochrome P450, family 11, subfamily B, polypeptide
Malignancy (2,464 words) [view diff] exact match in snippet view article find links to article
(2015). "Involvement of Cytochrome P450 in Reactive Oxygen Species Formation and Cancer". In Hardwick JP (ed.). Cytochrome P450 Function and Pharmacological
Didesmethylsibutramine (531 words) [view diff] exact match in snippet view article find links to article
SK, Cao S, Seo KA, Kim H, Kim MJ, Shon JH, et al. (August 2008). "Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine
Teicoplanin (1,836 words) [view diff] exact match in snippet view article find links to article
enzyme-bound intermediate is cyclized. Gene disruption studies indicate cytochrome P450 oxygenases as the enzymes that performs the coupling reactions. The
Molecular autopsy (1,910 words) [view diff] exact match in snippet view article find links to article
for forensic toxicology. This study is looking at the genotyping of cytochrome P450 3A4*1B and 3A5*3. Pharmacogenetics is the study of genetic contributions
3-hydroxyindolin-2-one monooxygenase (232 words) [view diff] exact match in snippet view article find links to article
some plants. Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation
Ticlopidine (1,681 words) [view diff] exact match in snippet view article find links to article
(2001). "Ticlopidine as selective mechanism-based inhibitor of human cytochrome P450 2C19". Biochemistry. 40 (40): 12112–12122. doi:10.1021/bi010254c. PMID 11580286
Absinthin (878 words) [view diff] exact match in snippet view article find links to article
Hydroxylation of terminal allylic carbon via Germacrene A hydroxylase, a cytochrome P450 enzyme. Oxidation of alcohol to aldol, via -germacrene A hydroxylase
Granulosa cell (1,011 words) [view diff] exact match in snippet view article find links to article
higher levels of mRNA expression of steroidogenic enzymes such as cytochrome P450. MGCs produce an increasing amount of estrogen which leads to the LH
Tricin (348 words) [view diff] exact match in snippet view article find links to article
1007/s11101-009-9161-5. Lam, PY; Zhu, FY; Chan, WL; Liu, H; Lo, C (2014). "Cytochrome P450 93G1 Is a Flavone Synthase II That Channels Flavanones to the Biosynthesis
Endothelium-derived hyperpolarizing factor (1,377 words) [view diff] exact match in snippet view article find links to article
one of four double bonds of the arachidonic acid carbon backbone by cytochrome P450 epoxygenase enzymes. In addition, in some cases hydrogen peroxide has
4'-Methyl-α-pyrrolidinobutiophenone (152 words) [view diff] exact match in snippet view article find links to article
Meyer MR, Theobald DS, Maurer HH (January 2008). "Identification of cytochrome P450 enzymes involved in the metabolism of the new designer drug
Taxane 13alpha-hydroxylase (249 words) [view diff] exact match in snippet view article find links to article
differential transformations of taxadien-5 alpha-ol and its acetate ester by cytochrome P450 hydroxylases from Taxus suspension cells". Arch. Biochem. Biophys.
Thiophene (2,252 words) [view diff] no match in snippet view article find links to article
(1991). "Thiophene S-oxides as new reactive metabolites: Formation by cytochrome-P450 dependent oxidation and reaction with nucleophiles". J. Am. Chem. Soc
2-Hydroxy-1,4-benzoxazin-3-one monooxygenase (173 words) [view diff] exact match in snippet view article find links to article
PMID 16668055. Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation
18-Hydroxycorticosterone (251 words) [view diff] exact match in snippet view article find links to article
Aldosterone synthase Reddish MJ, Guengerich FP (August 2019). "Human cytochrome P450 11B2 produces aldosterone by a processive mechanism due to the lactol
Perhexiline (869 words) [view diff] exact match in snippet view article find links to article
Pharmacology. 55:635–8, (2003). Zanger, U.M., Raimundo, S., Eichelbaum, M., Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.
Pharmaceutical bioinformatics (350 words) [view diff] exact match in snippet view article find links to article
Olsen, Lars (2010-06-10). "SMARTCyp: A 2D Method for Prediction of Cytochrome P450-Mediated Drug Metabolism". ACS Medicinal Chemistry Letters. 1 (3):
Alprazolam (8,005 words) [view diff] exact match in snippet view article find links to article
hours. Alprazolam is metabolized in the liver, mostly by the enzyme cytochrome P450 3A4 (CYP3A4). Two major metabolites are produced: 4-hydroxyalprazolam
FMO5 (835 words) [view diff] exact match in snippet view article find links to article
"Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450". Jpn. J. Pharmacol. 84 (2): 213–20. doi:10.1254/jjp.84.213. PMID 11128045
Sudan III (372 words) [view diff] exact match in snippet view article find links to article
Moustafa GG, Sakamoto KQ, Ishizuka M, Fujita S (2008). "The induction of cytochrome P450 1A1 by Sudan dyes". J. Biochem. Mol. Toxicol. 22 (2): 77–84. doi:10
Hydroxyflavone (60 words) [view diff] exact match in snippet view article find links to article
flavonols 6-Hydroxyflavone, one of the noncompetitive inhibitors of cytochrome P450 2C9 This set index page lists chemical compounds articles associated
Entropy (journal) (432 words) [view diff] exact match in snippet view article
Samsel, Anthony; Stephanie Seneff (2013). "Glyphosate's Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways
Bisnortilidine (69 words) [view diff] exact match in snippet view article find links to article
D.; Mikus, G.; Weiss, J. (2012). "In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite
Jeotgalicoccus (314 words) [view diff] exact match in snippet view article find links to article
2014). "Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium". Journal
Aromatization (1,113 words) [view diff] exact match in snippet view article find links to article
1080/01614949208020306. Lephart, E. D. (1996). "A review of brain aromatase cytochrome P450". Brain Res. Rev. 22 (1): 1–26. doi:10.1016/0165-0173(96)00002-1. PMID 8871783
Hypericum androsaemum (707 words) [view diff] exact match in snippet view article find links to article
intermediate is subsequently converted by a benzophenone 3′-hydroxylase, a cytochrome P450 monooxygenase, leading to the formation of 2,3′,4,6-tetrahydroxybenzophenone
Flavin containing monooxygenase 1 (849 words) [view diff] exact match in snippet view article find links to article
187. PMID 12527699. Attar M, Dong D, Ling KH, Tang-Liu DD (2003). "Cytochrome P450 2C8 and flavin-containing monooxygenases are involved in the metabolism
TYMP (gene) (1,080 words) [view diff] exact match in snippet view article
Yamazaki H, Shimada N, et al. (2001). "Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from
Landiolol (2,641 words) [view diff] exact match in snippet view article find links to article
metabolic activity of different cytochrome P450 molecular species (CYP1A2, 2C9, 2C19, 2D6 and 3A4) in vitro. The cytochrome P450 content was not affected in
Adrenodoxin reductase (1,938 words) [view diff] exact match in snippet view article find links to article
I (1996). "Electron transfer proteins of cytochrome P450 systems". Physiological Functions of Cytochrome P450 in Relation to Structure and Regulation (PDF)
Tybamate (189 words) [view diff] exact match in snippet view article find links to article
of phenobarbital and five 1,3-propanediol dicarbamates for hepatic cytochrome P450 induction in rats". Research Communications in Chemical Pathology and
Hydrocodone/paracetamol (1,855 words) [view diff] exact match in snippet view article find links to article
metabolized to norhydrocodone by cytochrome P450 3A4 and to hydromorphone, also biologically active, by cytochrome P450 2D6. For individuals who have a
Tropine acyltransferase (253 words) [view diff] exact match in snippet view article find links to article
genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement". Chemistry & Biology. 13 (5):
Leukotriene A4 (568 words) [view diff] exact match in snippet view article find links to article
cyclooxygenase pathway (also PGH synthase pathway), isoprostane pathway, and cytochrome P450 epoxygenases pathway following the arachidonic acid metabolism, but
1,3-Benzodioxole (167 words) [view diff] exact match in snippet view article find links to article
inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation", Curr. Drug Metab. 2000, volume 1, 67-84
Pseudobaptigenin synthase (107 words) [view diff] exact match in snippet view article find links to article
step in the biosynthesis of (-)-maackiain. Clemens S, Barz W (1996). "Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum". Phytochemistry
Oleanolic acid (828 words) [view diff] case mismatch in snippet view article find links to article
After the formation of beta amyrin, CYP716AATR2, also known as a cytochrome p450 enzyme, oxidizes carbon 28 turning it into alcohol. CYP716AATR2 converts
Astex Pharmaceuticals (1,034 words) [view diff] exact match in snippet view article find links to article
Vonrhein, C; Tickle, I. J.; Jhoti, H (2004). "Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone". Science. 305 (5684): 683–6
HLA-B (1,873 words) [view diff] case mismatch in snippet view article find links to article
ALLORECOGNITION: THE STRUCTURE OF HLA-B35011 PRESENTING AN EPITOPE DERIVED FROM CYTOCHROME P450. 2fyy: The role of T cell receptor alpha genes in directing human MHC
15α-Hydroxyestradiol (140 words) [view diff] exact match in snippet view article find links to article
metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5". J. Pharmacol. Exp. Ther. 298 (2): 420–32. PMID 11454902
Cruciferous vegetables (1,237 words) [view diff] exact match in snippet view article find links to article
2000). "Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response
Linoleate 8R-lipoxygenase (254 words) [view diff] exact match in snippet view article find links to article
a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450". The Journal of Biological Chemistry. 284 (18): 11792–805. doi:10
4'-Methyl-α-pyrrolidinohexiophenone (451 words) [view diff] exact match in snippet view article find links to article
in fission yeast heterologously expressing human cytochrome P450 2D6--a versatile alternative to multistep chemical synthesis". Journal
Ebastine (794 words) [view diff] exact match in snippet view article find links to article
administration, ebastine undergoes extensive first-pass metabolism by hepatic cytochrome P450 3A4 into its active carboxylic acid metabolite, carebastine. This conversion
Mevastatin (708 words) [view diff] case mismatch in snippet view article find links to article
that the oxidations are preformed by a polypeptide that is similar to cytochrome p450 monooxygenase, which is encoded by mlcC within the mevastatin gene
Premnaspirodiene oxygenase (142 words) [view diff] exact match in snippet view article find links to article
2007). "Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene
Monoclonal antibody (4,361 words) [view diff] exact match in snippet view article find links to article
Gastrointestinal perforation Mucositis List of monoclonal antibodies "Cytochrome P450 Mediated Drug and Carcinogen Metabolism using Monoclonal Antibodies"
Tricresyl phosphate (2,145 words) [view diff] exact match in snippet view article find links to article
through urine and feces, it is partially metabolized by the hepatic cytochrome P450 system. Pathways include hydroxylation at one or more methyl groups
UCHL3 (688 words) [view diff] case mismatch in snippet view article find links to article
A, Sekine A, et al. (2003). "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese
Germacrene A hydroxylase (176 words) [view diff] exact match in snippet view article find links to article
germacrene A carboxylic acid in chicory roots. Demonstration of a cytochrome P450 (+)-germacrene a hydroxylase and NADP+-dependent sesquiterpenoid dehydrogenase(s)
Chimera (molecular biology) (786 words) [view diff] exact match in snippet view article
1128/AEM.06516-11. PMC 3264099. PMID 22101057. "Entrez Gene: CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18". National Center for Biotechnology
Aristolochic acid (2,600 words) [view diff] exact match in snippet view article find links to article
benzyltetrahydroisoquinolines to aporphines. A potential role for CYP80G2, a cytochrome P450 that has been demonstrated to catalyze the intramolecular C-C phenol
27-Hydroxycholesterol (238 words) [view diff] exact match in snippet view article find links to article
Mast N, Lin JB, Pikuleva IA (2015). "Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy". Mol
AADAC (529 words) [view diff] case mismatch in snippet view article find links to article
A, Sekine A, et al. (2003). "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese
Terfenadine (780 words) [view diff] exact match in snippet view article find links to article
metabolized to the active form fexofenadine in the liver by the enzyme cytochrome P450 3A4. Due to its near complete metabolism by the liver immediately after
Mitomycins (975 words) [view diff] exact match in snippet view article find links to article
Hydroxylation of C-5, C-7 (followed by transamination), and C-9a. – Likely via cytochrome P450 monooxygenase or benzoate hydroxylase O-Methylation at C-9a – Likely
Afimoxifene (453 words) [view diff] exact match in snippet view article find links to article
evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6". J Pharmacol
Benzoxazinone biosynthesis (441 words) [view diff] exact match in snippet view article find links to article
M; Kliem, R; Saedler, H; Gierl, A (Jan 6, 1995). "Expression of a cytochrome P450 gene family in maize". Molecular & General Genetics. 246 (1): 100–9
Simcyp (586 words) [view diff] exact match in snippet view article find links to article
ratios of different standards used for immunoquantification of hepatic cytochrome P450 enzymes". Drug Metabolism and Disposition. 35 (10): 1733–1736. doi:10
Stokesia laevis (230 words) [view diff] case mismatch in snippet view article find links to article
(2002). Transgenic production of epoxy fatty acids by expression of a cytochrome p450 enzyme from Euphorbia lagascae seed. Plant Physiology 128(2), 615-24
6',7'-Dihydroxybergamottin (239 words) [view diff] exact match in snippet view article find links to article
(December 1996). "Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice". Drug Metabolism and Disposition. 24
Nornicotine (508 words) [view diff] exact match in snippet view article find links to article
nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase". Proceedings of the National Academy of Sciences. 102
Campine chicken (913 words) [view diff] exact match in snippet view article find links to article
Journal of Heredity 81 (2): 107-110. (subscription required) 107910: Cytochrome P450, family 19, subfamily A, polypeptide 1; CYP19A1. Online Mendelian Inheritance
20α-Dihydrodydrogesterone (199 words) [view diff] exact match in snippet view article find links to article
"Dydrogesterone metabolism in human liver by aldo-keto reductases and cytochrome P450 enzymes". Xenobiotica. 46 (10): 868–874. doi:10.3109/00498254.2015