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Longer titles found: Cyclin E/Cdk2 (view), Cyclin E1 (view), Cyclin E2 (view)

searching for Cyclin E 41 found (98 total)

alternate case: cyclin E

Control of chromosome duplication (2,036 words) [view diff] exact match in snippet view article find links to article

frog embryos, cyclin E-Cdk2 is primarily responsible for activating origins. Removal of cyclin E with antibodies blocks replication. Cyclin E-CDk2 is also

Ubiquitin (11,029 words) [view diff] exact match in snippet view article find links to article

of cyclins or CDKs levels through ubiquitylation and degradation. When cyclin E is partnered with CDK2 and gets phosphorylated, an SCF-associated F-box

NPAT (gene) (929 words) [view diff] exact match in snippet view article

Hori T, Harlow E (Feb 1998). "Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry". Genes & Development. 12 (4): 456–61. doi:10

Cyclin D/Cdk4 (2,805 words) [view diff] exact match in snippet view article find links to article

regions. These genes include the cyclin E and A genes, and other genes associated with the G1/S transition. Synthesis of cyclin E and subsequent binding to constitutively

MAPK/ERK pathway (3,068 words) [view diff] exact match in snippet view article find links to article

transcriptional activity, preventing expression of S-phase entry genes including Cyclin E, Cyclin A2 and Emi1. ERK1/2 activation downstream of mitogen induced Ras

Histone (9,582 words) [view diff] exact match in snippet view article find links to article

transcription on chromosomes 1 and 6 of human cells. NPAT is also a substrate of cyclin E-Cdk2, which is required for the transition between G1 phase and S phase

SCF complex (2,021 words) [view diff] exact match in snippet view article find links to article

substrates of SCF complexes include: cyclin family proteins: Cyclin D, Cyclin E transcriptional regulators: Myc, E2f1, p130 cyclin-dependent kinase inhibitors

CCNC (gene) (1,235 words) [view diff] exact match in snippet view article

mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)". Cytogenet. Cell Genet. 69 (3–4):

Fasudil (1,191 words) [view diff] exact match in snippet view article find links to article

protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells". The Journal of Biological Chemistry. 276 (37): 34958–65

E2F5 (1,232 words) [view diff] exact match in snippet view article find links to article

Allen KE, La Thangue NB (Apr 2000). "Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators". Nature Cell Biology

CDKN3 (1,041 words) [view diff] exact match in snippet view article find links to article

mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)". Cytogenet Cell Genet. 69 (3–4): 190–2

RhoC (1,931 words) [view diff] exact match in snippet view article find links to article

GTP-ase Activating Protein): an effector of RhoC to enhance expression of cyclin E and cyclin D1. This resulted in cells being promoted to enter S phase more

CIP/KIP (2,181 words) [view diff] exact match in snippet view article find links to article

of G1/S and S-phase cyclin-CDK complexes including cyclin D-CDK4,6 and cyclin E-, A-CDK2 complexes. Traditionally it was assumed that CIP/KIP proteins

Retinoblastoma-like protein 1 (1,999 words) [view diff] exact match in snippet view article find links to article

S2CID 21761703. Shanahan F, Seghezzi W, Parry D, Mahony D, Lees E (Feb 1999). "Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex

Coilin (1,351 words) [view diff] exact match in snippet view article find links to article

Kung H, Matera AG (2000). "Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies". J. Cell Sci. 113 (9): 1543–52. doi:10

Embryonic diapause (1,832 words) [view diff] exact match in snippet view article find links to article

dacapo gene in the fruit fly, responsible for inhibiting the formation of cyclin E-cdk2 complexes necessary for DNA synthesis. There is also evidence pointing

Basal-like carcinoma (1,741 words) [view diff] exact match in snippet view article find links to article

gene and high expression of E2F Transcription Factor 3 (E2F-3) as well as Cyclin E genes. The Cyclin D-CDK4/CDK6 complex phosphorylates RB and promotes cell

S phase index (106 words) [view diff] exact match in snippet view article find links to article

SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation", Journal of Cell Science 116, 2321-2332 (2003). v t e

SMARCD3 (768 words) [view diff] exact match in snippet view article find links to article

PMID 8895581. Shanahan F, Seghezzi W, Parry D, Mahony D, Lees E (February 1999). "Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex

CCT7 (870 words) [view diff] exact match in snippet view article find links to article

Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998). "Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT". Molecular and Cellular

APPBP1 (2,792 words) [view diff] exact match in snippet view article find links to article

NF-κB transcription factor inhibitor pIκBα, and the cell cycle regulators cyclin E and p27. Thus, APPBP1 carries out an initiating step that controls major

CCT4 (827 words) [view diff] exact match in snippet view article find links to article

Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998). "Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT". Molecular and Cellular

NEDD8 (2,836 words) [view diff] exact match in snippet view article find links to article

Gurian-West M, Clurman B, Roberts JM (September 1999). "Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells". Genes & Development

MIZF (763 words) [view diff] exact match in snippet view article find links to article

van Wijnen AJ, Stein JL, Stein GS (2005). "HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell

SMARCC1 (1,285 words) [view diff] exact match in snippet view article find links to article

PMID 9744861. Shanahan F, Seghezzi W, Parry D, Mahony D, Lees E (1999). "Cyclin E Associates with BAF155 and BRG1, Components of the Mammalian SWI-SNF Complex

DNA re-replication (2,860 words) [view diff] exact match in snippet view article find links to article

activates due to overexpression of cyclin E, which has been shown to be important in regulating the licensing system. When cyclin E is overexpressed in U-2-OS

CCT2 (gene) (835 words) [view diff] exact match in snippet view article

Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998). "Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT". Molecular and Cellular

TSG101 (1,970 words) [view diff] exact match in snippet view article find links to article

"TSG101 expression in gynecological tumors: relationship to cyclin D1, cyclin E, p53 and p16 proteins". Cell. Mol. Biol. (Noisy-le-grand). 47 (7): 1187–93

Neuronal cell cycle (2,128 words) [view diff] exact match in snippet view article find links to article

DNA replication (Liu et al., 1998). The G1/S transition is regulated by cyclin E binding to Cdk2 which phosphorylates Rb as well (Merrick and Fisher, 2011)

Merkel-cell carcinoma (5,542 words) [view diff] exact match in snippet view article find links to article

that LT may also preserve cell proliferation signals such as c-Myc and cyclin E and cause DNA injury to the p53 tumor suppressor. Meanwhile, sT has been

Biochemical cascade (11,432 words) [view diff] exact match in snippet view article find links to article

p19Arf-p53-P21Cip1 signaling pathways. Embryonic stem cells have constitutive cyclin E-CDK2 activity, which hyperphosphorylates and inactivates Rb. This leads

CREB-binding protein (5,272 words) [view diff] exact match in snippet view article find links to article

post-translational modifications. It turned out that administration of cyclin E/CDK2 inhibitors did in fact inhibit the enzymatic activity of CBP's KAT

Mesothelin (2,787 words) [view diff] exact match in snippet view article find links to article

"Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein

GADD45G (3,081 words) [view diff] exact match in snippet view article find links to article

interacts with CRIF, which causes the inhibition of Cdc2-cyclin B1 and Cdk-cyclin E. GADD45 also works with the cyclin-dependent kinase inhibitor p21, which

PELP-1 (3,909 words) [view diff] exact match in snippet view article find links to article

E2-mediated cell proliferation and is a substrate of CDK4/cyclin D1, CDK2/cyclin E and CDK2/cyclin A complexes. Studies using TG mice model suggested the

CUL4B (2,948 words) [view diff] exact match in snippet view article find links to article

CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation". Cell Cycle. 5 (1): 71–7. doi:10.4161/cc.5.1.2266. PMID 16322693

SKP2 (3,999 words) [view diff] exact match in snippet view article find links to article

cancer pathogenesis is p27Kip1, which is involved primarily in inhibiting cyclin E-CDK2 complexes (and to a lesser extent cyclin D-CDK4 complexes). Levels

Ovarian follicle activation (4,011 words) [view diff] exact match in snippet view article find links to article

inhibits cell cycle progression at the G1 phase by preventing the action of cyclin E-Cdk2. Due to its important role in the cell cycle, it is found within the

DREAM complex (3,065 words) [view diff] exact match in snippet view article find links to article

stimuli and subsequent cyclin-CDK activity. Increasing cyclin D-CDK4 and cyclin E-CDK2 activity dissociates the DREAM complex from the promoter by phosphorylation

Biochemical switches in the cell cycle (6,678 words) [view diff] exact match in snippet view article find links to article

to control the checkpoint: cell cycle kinases CDK4/6-cyclin D and CDK2-cyclin E. The transcription complex that includes Rb and E2F is important in controlling

CSNK1D (14,740 words) [view diff] exact match in snippet view article find links to article

protein kinase A (PKA), protein kinase B (Akt), cyclin-dependent kinase 2/cyclin E (CDK2/E) and cyclin-dependent kinase 5/p35 (CDK5/p35), CDC-like kinase