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searching for Chromosome segregation 195 found (257 total)

alternate case: chromosome segregation

Anaphase (714 words) [view diff] exact match in snippet view article find links to article

reach their overall maximum condensation in late anaphase, to help chromosome segregation and the re-formation of the nucleus. Anaphase starts when the anaphase
Crescentin (804 words) [view diff] exact match in snippet view article find links to article
crescentin protein. Some of its homologs are erroneously labelled Chromosome segregation protein ParA. This protein family is found in Caulobacter and Methylobacterium
Carpediemonas (1,458 words) [view diff] exact match in snippet view article find links to article
tracking complex and all subunits of the Ndc80 complex involved in chromosome segregation. ORC and Cdc6 are proteins in charge of replication initiation and
SMC3 (939 words) [view diff] exact match in snippet view article find links to article
family are key regulators of DNA repair, chromosome condensation and chromosome segregation. The domain organisation of SMC proteins is evolutionarily conserved
SMC1A (2,075 words) [view diff] exact match in snippet view article find links to article
family are key regulators of DNA repair, chromosome condensation and chromosome segregation from bacteria to humans. The domain organisation of SMC proteins
SMC5 (1,067 words) [view diff] exact match in snippet view article find links to article
involved in DNA repair, transcriptional pathways, regulation of chromosome segregation, and immunity in Arabidopsis. In eukaryotes the structural maintenance
CAS/CSE protein family (580 words) [view diff] no match in snippet view article find links to article
mammalian cellular apoptosis susceptibility (CAS) proteins and yeast chromosome-segregation protein, CSE1. CAS is involved in both cellular apoptosis and proliferation
NDC80 (1,170 words) [view diff] exact match in snippet view article find links to article
"Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes". The Journal of Cell Biology. 216 (2):
Kinetochore (7,769 words) [view diff] exact match in snippet view article find links to article
daughter cells. The kinetochore is therefore essential for the chromosome segregation that is classically associated with mitosis and meiosis. The kinetochore
Dynein (3,242 words) [view diff] no match in snippet view article find links to article
Dynein is a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work
Central spindle (224 words) [view diff] exact match in snippet view article find links to article
signaling faults in cytokinesis can occur, resulting in unequal chromosome segregation or polyploid cells, greatly increasing the risk of cancer. Douglas
Spindle pole body (1,004 words) [view diff] exact match in snippet view article find links to article
microtubule nucleation capacity of the SPB, which is important for chromosome segregation. All SPB proteins can be divided into three groups: core components
FtsK (1,317 words) [view diff] exact match in snippet view article find links to article
1329 amino acid protein involved in bacterial cell division and chromosome segregation. FtsK stands for "Filament temperature sensitive mutant K" because
TTK (gene) (806 words) [view diff] exact match in snippet view article
signaling • peptidyl-tyrosine phosphorylation • female meiosis chromosome segregation • peptidyl-serine phosphorylation • peptidyl-threonine phosphorylation
Tomo Tanaka (240 words) [view diff] exact match in snippet view article find links to article
Fellow. His research group has been studying the mechanisms of chromosome segregation in mitosis, chromosome organisation in the nucleus, and how abnormalities
CDC14B (753 words) [view diff] exact match in snippet view article find links to article
"Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation". Nat. Cell Biol. 4 (4): 318–322. doi:10.1038/ncb777. PMID 11901424
Kirsten Bomblies (377 words) [view diff] exact match in snippet view article find links to article
studies the evolution of meiosis, particularly recombination and chromosome segregation. In her spare time she does illustrations, etchings and other art
Chromatin remodeling (5,070 words) [view diff] exact match in snippet view article find links to article
biological processes, egg cells DNA replication and repair; apoptosis; chromosome segregation as well as development and pluripotency. Aberrations in chromatin
BUB3 (2,194 words) [view diff] exact match in snippet view article find links to article
kinetochore of BUB1. BUB3 serves in oocyte meiosis as the regulator of chromosome segregation. Defects in BUB3 in the cell cycle can contribute to the following
CDC14A (916 words) [view diff] exact match in snippet view article find links to article
"Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation". Nat. Cell Biol. 4 (4): 317–22. doi:10.1038/ncb777. PMID 11901424
MLH1 (3,422 words) [view diff] exact match in snippet view article find links to article
chromosome segregation • oogenesis • male meiosis chromosome segregation • cellular response to DNA damage stimulus • meiotic chromosome segregation
Separase (1,033 words) [view diff] exact match in snippet view article find links to article
negative regulation of sister chromatid cohesion • chromosome segregation • homologous chromosome segregation • proteolysis • positive regulation of mitotic
Cyclin (1,770 words) [view diff] exact match in snippet view article find links to article
prometaphase to ensure efficient error correction and faithful chromosome segregation. Cells must separate their chromosomes precisely, an event that
NEK2 (1,172 words) [view diff] exact match in snippet view article find links to article
regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation". J. Biol. Chem. 277 (51): 49408–16. doi:10.1074/jbc.M207069200
BUB1 (2,220 words) [view diff] exact match in snippet view article find links to article
PMID 15239953. Klebig C, Korinth D, Meraldi P (Jun 2009). "Bub1 regulates chromosome segregation in a kinetochore-independent manner". The Journal of Cell Biology
Cellular apoptosis susceptibility protein (324 words) [view diff] exact match in snippet view article find links to article
CSE1 chromosome segregation 1-like (yeast) Identifiers Symbol CSE1L NCBI gene 1434 HGNC 2431 OMIM 601342 RefSeq NM_001316 UniProt P55060 Other data Locus
STAG2 (441 words) [view diff] case mismatch in snippet view article find links to article
A.; Waldman, Todd (2016-02-12). "Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2". PLOS
ZNF207 (73 words) [view diff] exact match in snippet view article find links to article
Biological process • regulation of transcription, DNA-templated • chromosome segregation • protein stabilization • microtubule polymerization • mitotic spindle
ARL8A (247 words) [view diff] exact match in snippet view article find links to article
GTPase subfamily capable of associating with tubulin is required for chromosome segregation". Journal of Cell Science. 117 (Pt 20): 4705–15. doi:10.1242/jcs
ADP/ATP translocase 2 (1,924 words) [view diff] exact match in snippet view article find links to article
"MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation". Molecular Cell. 39 (4): 632–40. doi:10.1016/j.molcel.2010.07.029
Polyamine-modulated factor 1 (470 words) [view diff] exact match in snippet view article find links to article
human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". The Journal of Cell Biology. 173 (1): 9–17. doi:10.1083/jcb.200509158
Spindle apparatus (3,288 words) [view diff] exact match in snippet view article find links to article
have roles in remodeling the mitotic spindle as well as promoting chromosome segregation during anaphase. The activities of these MAPs are carefully regulated
MIS12 (649 words) [view diff] exact match in snippet view article find links to article
human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10.1083/jcb.200509158. PMC 2063780
SGOL1 (1,211 words) [view diff] exact match in snippet view article find links to article
"PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation". Developmental Cell. 10 (5): 575–85. doi:10.1016/j.devcel.2006
ARL8B (554 words) [view diff] exact match in snippet view article find links to article
GTPase subfamily capable of associating with tubulin is required for chromosome segregation". J. Cell Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635
DSN1 (687 words) [view diff] exact match in snippet view article find links to article
human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10.1083/jcb.200509158. PMC 2063780
Non-random segregation of chromosomes (7,205 words) [view diff] exact match in snippet view article find links to article
As explained by the immortal DNA strand hypothesis, non-random chromosome segregation has a unique significance in asymmetric stem cell division; the
Centrosome cycle (2,137 words) [view diff] exact match in snippet view article find links to article
mammalian cells. Failure of centrosome regulation can cause mistakes in chromosome segregation and is associated with aneuploidy. A centrosome is composed of two
SMC6 (1,310 words) [view diff] exact match in snippet view article find links to article
via recombination • cellular senescence • positive regulation of chromosome segregation • double-strand break repair via homologous recombination • DNA
NSL1 (646 words) [view diff] exact match in snippet view article find links to article
human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10.1083/jcb.200509158. PMC 2063780
CellCognition (461 words) [view diff] exact match in snippet view article find links to article
Poser I, Hyman AA, Gerlich DW (2012). "Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores". Journal of
SUV39H1 (1,545 words) [view diff] exact match in snippet view article find links to article
Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. SUV39H1 has been shown to interact with:
CENPT (553 words) [view diff] exact match in snippet view article find links to article
CENP-A containing nucleosome assembly • chromosome organization • chromosome segregation • cell division • cell cycle • protein localization to kinetochore
Nuclear mitotic apparatus protein 1 (1,076 words) [view diff] exact match in snippet view article find links to article
regulation of hair follicle development • positive regulation of chromosome segregation • anastral spindle assembly • regulation of mitotic spindle organization
KNL1 (990 words) [view diff] exact match in snippet view article find links to article
"Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes". The Journal of Cell Biology. 216 (2):
WAPAL (634 words) [view diff] exact match in snippet view article find links to article
• regulation of cohesin loading • cell division • regulation of chromosome segregation • cell cycle • GO:0022415 viral process • protein localization to
KIAA0157 (396 words) [view diff] exact match in snippet view article find links to article
nucleus • microtubule minus-end • cytosol Biological process • chromosome segregation • cell division • mitotic spindle assembly • response to ischemia
FAM214A (1,908 words) [view diff] exact match in snippet view article find links to article
DUF4210 and Chromosome_Seg have been predicted to play a role in chromosome segregation during meiosis. The FAM214A gene is located on the negative DNA
Aurora B kinase (4,670 words) [view diff] exact match in snippet view article find links to article
phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation". The Journal of Cell Biology. 153 (4): 865–80. doi:10.1083/jcb
Neocentromere (4,100 words) [view diff] exact match in snippet view article find links to article
to carry out the functions of normal centromeres in regulating chromosome segregation and inheritance. This raises many questions on what is necessary
CSE (428 words) [view diff] no match in snippet view article find links to article
and epidural anaesthesia, an anaesthetic technique CSE1, a yeast chromosome-segregation protein and member of the CAS/CSE protein family Cystathionine gamma-lyase
Melina Schuh (818 words) [view diff] exact match in snippet view article find links to article
2015). "Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes". Science. 348 (6239): 1143–1147. doi:10
PTTG1 (1,376 words) [view diff] exact match in snippet view article find links to article
nucleus • cytosol Biological process • chromosome segregation • chromosome organization • homologous chromosome segregation • cellular response to DNA damage
Chromosome instability (3,332 words) [view diff] exact match in snippet view article find links to article
whole chromosomes; causing aneuploidy. Normal cells make errors in chromosome segregation in 1% of cell divisions, whereas cells with CIN make these errors
EIF3S6 (1,083 words) [view diff] exact match in snippet view article find links to article
fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14370–5. Bibcode:2000PNAS
MSH4 (1,489 words) [view diff] exact match in snippet view article find links to article
frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae". Genetics. 199 (2): 399–412. doi:10
SGOL2 (1,132 words) [view diff] exact match in snippet view article find links to article
named cohesin. This protective system is essential for faithful chromosome segregation during mitosis and meiosis, which is the physical basis of Mendelian
NEK6 (1,158 words) [view diff] exact match in snippet view article find links to article
important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation
Nucleoporin 43 (785 words) [view diff] exact match in snippet view article find links to article
pore outer ring • host cell Biological process • mRNA transport • chromosome segregation • cell division • protein transport • cell cycle • GO:0022415 viral
Viji Draviam (632 words) [view diff] exact match in snippet view article find links to article
essential for spindle pole organization in human somatic cells Chromosome segregation and genomic stability Draviam serves as an editor of the scientific
SMC2 (644 words) [view diff] exact match in snippet view article find links to article
meiotic chromosome condensation • chromosome organization • meiotic chromosome segregation • cell division • chromosome condensation • cell cycle • mitotic
SMC4 (741 words) [view diff] exact match in snippet view article find links to article
Biological process • mitotic sister chromatid segregation • meiotic chromosome segregation • cell division • cell cycle • kinetochore organization • mitotic
40S ribosomal protein S3 (1,016 words) [view diff] exact match in snippet view article find links to article
density • ribonucleoprotein complex • synapse Biological process • chromosome segregation • positive regulation of endodeoxyribonuclease activity • cellular
Mendel Lectures (853 words) [view diff] exact match in snippet view article find links to article
European Institute of Oncology, Milan, Italy "Molecular bases of chromosome segregation" 6 39 March 29, 2009 Jonas Frisén Karolinska Institutet, Stockholm
CSM1 (244 words) [view diff] exact match in snippet view article find links to article
with kinetochores during anaphase and is required for accurate chromosome segregation". Cell Cycle. 9 (17): 3611–8. doi:10.4161/cc.9.17.12885. PMC 3047622
CENPC1 (916 words) [view diff] exact match in snippet view article find links to article
furrow • intercellular bridge • Flemming body Biological process • chromosome segregation • cell division • kinetochore assembly • cell cycle • CENP-A containing
FAM214B (1,329 words) [view diff] exact match in snippet view article find links to article
DUF4210 domain of unknown function at the position 348 to 402, and a chromosome segregation domain at position 480 to 536. The DUF4210 domain is currently has
Combretastatin (602 words) [view diff] exact match in snippet view article find links to article
movement, cell movement, and formation of the mitotic spindle used in chromosome segregation and cellular division. The anti-cancer activity from this action
Divisome (1,385 words) [view diff] exact match in snippet view article find links to article
interactions between the division machinery and DNA replication during chromosome segregation in E. coli. The precise assembly process of the divisome is not
Haldane's rule (1,267 words) [view diff] case mismatch in snippet view article find links to article
A.F. (ed.). "Species-specific heterochromatin prevents mitotic chromosome Segregation to Cause hybrid lethality in Drosophila". PLOS Biology. 7 (10):
STAG1 (278 words) [view diff] exact match in snippet view article find links to article
complex • nuclear matrix • mitotic spindle pole Biological process • chromosome segregation • cell division • cell cycle • transcription by RNA polymerase II
J. Richard McIntosh (3,405 words) [view diff] exact match in snippet view article find links to article
force generated. Here, the researchers applied these findings to chromosome segregation and concluded that the microtubule dynamics create the forces needed
Population change (687 words) [view diff] exact match in snippet view article find links to article
declines with age. One of the biological reasons for this is abnormal chromosome segregation during cell division in older eggs. In some parts of society there
NCAPH (863 words) [view diff] exact match in snippet view article find links to article
chromosome condensation • meiotic chromosome condensation • meiotic chromosome segregation • positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
Acetylation (5,175 words) [view diff] exact match in snippet view article find links to article
shift in protein N-terminal acetylation and is important for normal chromosome segregation". PLOS Genet. 7 (7): e1002169. doi:10.1371/journal.pgen.1002169
USP44 (466 words) [view diff] exact match in snippet view article find links to article
GO:0060564, GO:1904190 negative regulation of ubiquitin protein ligase activity • protein deubiquitination • chromosome segregation Sources:Amigo / QuickGO
Molecular motor (1,854 words) [view diff] exact match in snippet view article find links to article
Dworkin J, Losick R (October 2002). "Does RNA polymerase help drive chromosome segregation in bacteria?". Proceedings of the National Academy of Sciences of
Centromere protein E (996 words) [view diff] exact match in snippet view article find links to article
• microtubule plus-end directed mitotic chromosome migration • chromosome segregation • mitotic metaphase plate congression • attachment of mitotic spindle
PPP1R7 (466 words) [view diff] exact match in snippet view article find links to article
Biological process • positive regulation of protein dephosphorylation • chromosome segregation • GO:0048552 regulation of catalytic activity • regulation of phosphoprotein
MIS18A (575 words) [view diff] exact match in snippet view article find links to article
• cell division • regulation of DNA methylation • cell cycle • chromosome segregation • CENP-A containing nucleosome assembly Sources:Amigo / QuickGO
Japan Academy Prize (academics) (1,357 words) [view diff] case mismatch in snippet view article
Fujishima 2003 (93rd) Mitsuhiro Yanagida - Regulation of Cell Cycle and Chromosome Segregation Noboru Karashima - History and Society in South India: The Cholas
Robin Allshire (2,428 words) [view diff] exact match in snippet view article find links to article
gene silencing to gain fundamental insights into the processes of chromosome segregation, and heterochromatin and kinetochore CENP-A chromatin establishment
BEX4 (131 words) [view diff] exact match in snippet view article find links to article
microtubule • spindle pole • cytoskeleton Biological process • chromosome segregation • regulation of cell migration • regulation of cell population proliferation
DNA replication factor CDT1 (1,420 words) [view diff] exact match in snippet view article find links to article
cycle • regulation of DNA-dependent DNA replication initiation • chromosome segregation • attachment of mitotic spindle microtubules to kinetochore • GO:0007067
NDE1 (778 words) [view diff] exact match in snippet view article find links to article
ciliary basal body-plasma membrane docking • microtubule nucleation • chromosome segregation • mitotic centrosome separation • cell migration • vesicle transport
MMS19 (584 words) [view diff] exact match in snippet view article find links to article
Biological process • regulation of transcription, DNA-templated • chromosome segregation • DNA metabolic process • cellular response to DNA damage stimulus
Coactivator (genetics) (1,690 words) [view diff] exact match in snippet view article
shift in protein N-terminal acetylation and is important for normal chromosome segregation". PLOS Genetics. 7 (7): e1002169. doi:10.1371/journal.pgen.1002169
Oenothera (1,707 words) [view diff] exact match in snippet view article find links to article
apparently has non-Mendelian genetic consequences; with this mode of chromosome segregation and a system of balanced-lethal genes, genetic recombination is
Sperm-associated antigen 5 (565 words) [view diff] exact match in snippet view article find links to article
organization • cell division • protein localization to centrosome • chromosome segregation • regulation of attachment of spindle microtubules to kinetochore
Cdc14 (2,731 words) [view diff] exact match in snippet view article find links to article
"Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation". Nature. 433 (7022): 171–176. Bibcode:2005Natur.433..171H. doi:10
NAS Award in Molecular Biology (1,692 words) [view diff] exact match in snippet view article find links to article
have provided insight into the mechanism of the central process of chromosome segregation and the regulation of segregation. Gregory J. Hannon (2007) For
RGS14 (1,160 words) [view diff] exact match in snippet view article find links to article
• regulation of G protein-coupled receptor signaling pathway • chromosome segregation • learning • response to oxidative stress • cell division • positive
TOP2A (564 words) [view diff] exact match in snippet view article find links to article
chromosome condensation • embryonic cleavage • rhythmic process • chromosome segregation • DNA metabolic process • protein sumoylation • cellular response
CEP290 (1,614 words) [view diff] exact match in snippet view article find links to article
13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and
HORMAD1 (682 words) [view diff] exact match in snippet view article find links to article
mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis". PLOS Genetics. 6 (11): e1001190. doi:10.1371/journal
Whitehead Institute (2,028 words) [view diff] exact match in snippet view article find links to article
proteins that assemble at the centromere and that are required for chromosome segregation and cell division; defining the roles of the different components
ZWINT (814 words) [view diff] exact match in snippet view article find links to article
sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control". Oncogene. 25 (52): 6901–14. doi:10
CIAO1 (656 words) [view diff] exact match in snippet view article find links to article
assembly • positive regulation of cell population proliferation • chromosome segregation • protein maturation by iron-sulfur cluster transfer Sources:Amigo
REC8 (734 words) [view diff] exact match in snippet view article find links to article
complex Biological process • reciprocal meiotic recombination • chromosome segregation • male meiosis I • sister chromatid cohesion • seminiferous tubule
ESCO2 (854 words) [view diff] exact match in snippet view article find links to article
• nucleoplasm • cell junction • chromosome Biological process • chromosome segregation • post-translational protein acetylation • cell cycle • protein
Ki-67 (protein) (1,371 words) [view diff] exact match in snippet view article
regeneration • hyaluronan metabolic process • cell cycle • regulation of chromosome segregation • cell population proliferation • regulation of mitotic nuclear
Lamin (2,196 words) [view diff] exact match in snippet view article find links to article
allows chromatin to condense and the DNA to be replicated. After chromosome segregation, dephosphorylation of nuclear lamins by a phosphatase promotes reassembly
CDK5RAP2 (1,224 words) [view diff] exact match in snippet view article find links to article
neurogenesis • negative regulation of neuron differentiation • chromosome segregation • positive regulation of transcription, DNA-templated • brain development
STAG3 (gene) (691 words) [view diff] exact match in snippet view article
cell cycle • GO:0007126 meiotic cell cycle • synaptonemal complex assembly • chromosome segregation • sister chromatid cohesion Sources:Amigo / QuickGO
A22 (antibiotic) (249 words) [view diff] exact match in snippet view article
the cytoskeleton of bacteria, causing defects of morphology and chromosome segregation. "MreB Perturbing Compound A22". www.emdmillipore.com. Retrieved
Centrosomal protein 85 (139 words) [view diff] exact match in snippet view article find links to article
process • regulation of mitotic centrosome separation • negative regulation of protein kinase activity • chromosome segregation Sources:Amigo / QuickGO
CDK5RAP2 (1,224 words) [view diff] exact match in snippet view article find links to article
neurogenesis • negative regulation of neuron differentiation • chromosome segregation • positive regulation of transcription, DNA-templated • brain development
Stephen C. West (1,110 words) [view diff] exact match in snippet view article find links to article
are regulated so that they act late in the cell cycle to ensure chromosome segregation. In addition to the discovery of cellular Holliday junction resolvases
Kim Nasmyth (1,580 words) [view diff] exact match in snippet view article find links to article
Nasmyth co-discovered the APC/C and showed that its activity induces chromosome segregation. Using temperature-sensitive mutants of the APC/C he found several
Cytoplasmic incompatibility (1,336 words) [view diff] exact match in snippet view article find links to article
Tram, U, Fredrick, K, Werren, J, Sullivan, W (2006). "Paternal chromosome segregation during the first mitotic division determines Wolbachia-induced cytoplasmic
MLF1IP (731 words) [view diff] exact match in snippet view article find links to article
kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation". Mol. Cell. 24 (3): 409–22. doi:10.1016/j.molcel.2006.10.016. PMID 17081991
Pseudolinkage (635 words) [view diff] exact match in snippet view article find links to article
progeny. In translocation heterozygote, however, certain patterns of chromosome segregation during meiosis produce genetically unbalanced gametes that at fertilization
TOP3B (734 words) [view diff] exact match in snippet view article find links to article
activity Cellular component • condensed chromosome • nucleus Biological process • chromosome segregation • DNA topological change Sources:Amigo / QuickGO
Chromatin bridge (1,030 words) [view diff] exact match in snippet view article find links to article
2011.07.001. PMID 21782962. Jallepalli PV, Lengauer C (2001). "Chromosome segregation and cancer: cutting through the mystery". Nature Reviews Cancer
PUM2 (873 words) [view diff] exact match in snippet view article find links to article
membrane • cytoplasm • cytosol Biological process • regulation of chromosome segregation • regulation of gene silencing by miRNA • positive regulation of
TLK2 (990 words) [view diff] exact match in snippet view article find links to article
GO:0007243 intracellular signal transduction • phosphorylation • chromosome segregation • regulation of chromatin assembly or disassembly • cellular response
Epulopiscium (1,085 words) [view diff] exact match in snippet view article find links to article
David R.; Angert, Esther R. (2018). "Developmental stage influences chromosome segregation patterns and arrangement in the extremely polyploid, giant bacterium
RAD21 (5,890 words) [view diff] exact match in snippet view article find links to article
function that is evolutionarily conserved and essential for proper chromosome segregation, chromosomal architecture, post-replicative DNA repair, and the
ECT2 (1,043 words) [view diff] exact match in snippet view article find links to article
"Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner". J. Biol. Chem. 280 (43):
MAGEA5 (192 words) [view diff] exact match in snippet view article find links to article
function • molecular function Cellular component • cellular component Biological process • regulation of chromosome segregation Sources:Amigo / QuickGO
RCC1 (1,269 words) [view diff] exact match in snippet view article find links to article
• chromosome • protein-containing complex Biological process • chromosome segregation • G1 phase • GO:0043148 mitotic spindle organization • cell division
PUM1 (857 words) [view diff] exact match in snippet view article find links to article
cell cycle • posttranscriptional gene silencing • regulation of chromosome segregation • positive regulation of RIG-I signaling pathway • mRNA destabilization
Prokaryotic cytoskeleton (2,919 words) [view diff] exact match in snippet view article find links to article
separating the plasmids. The system is analogous to eukaryotic chromosome segregation as ParM acts like eukaryotic tubulin in the mitotic spindle, ParR
POT1 (1,240 words) [view diff] exact match in snippet view article find links to article
recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Alternatively spliced transcript variants have been described.
Flap structure-specific endonuclease 1 (2,440 words) [view diff] exact match in snippet view article find links to article
the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage". Mol. Cell. Biol. 14 (7): 4878–88
USP9X (1,486 words) [view diff] exact match in snippet view article find links to article
gamete generation • ubiquitin-dependent protein catabolic process • chromosome segregation • neuron migration • negative regulation of transcription by RNA
Needhi Bhalla (324 words) [view diff] exact match in snippet view article find links to article
research in Andrew W. Murray's lab where she researched mitotic chromosome segregation in yeast. Bhalla researched meiosis in C. elegans during her postdoctoral
PPP2R1A (1,302 words) [view diff] exact match in snippet view article find links to article
• ceramide metabolic process • regulation of DNA replication • chromosome segregation • inactivation of MAPK activity • protein dephosphorylation • meiotic
CTCF (2,686 words) [view diff] exact match in snippet view article find links to article
chromatid cohesion • regulation of molecular function, epigenetic • chromosome segregation • nucleosome positioning • transcription, DNA-templated • positive
Spo11 (1,071 words) [view diff] exact match in snippet view article find links to article
and C. elegans undergo meiotic crossover recombination and proper chromosome segregation when dU:dG lesions are produced in their DNA. This crossover recombination
ERCC2 (1,825 words) [view diff] exact match in snippet view article find links to article
cleavage • hair follicle maturation • multicellular organism growth • chromosome segregation • transcription initiation from RNA polymerase I promoter • transcription
FtsZ (2,968 words) [view diff] exact match in snippet view article find links to article
LJ, Errington J (June 2004). "Coordination of cell division and chromosome segregation by a nucleoid occlusion protein in Bacillus subtilis". Cell. 117
MSH5 (1,435 words) [view diff] exact match in snippet view article find links to article
assembly • resolution of meiotic recombination intermediates • reciprocal meiotic recombination • homologous chromosome segregation Sources:Amigo / QuickGO
Barrier to autointegration factor 1 (1,052 words) [view diff] exact match in snippet view article find links to article
process • nuclear transport • negative regulation of viral genome replication • chromosome segregation • chromosome condensation Sources:Amigo / QuickGO
Varidnaviria (3,328 words) [view diff] exact match in snippet view article find links to article
superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging". Nucleic Acids Res. 32
TLK1 (1,192 words) [view diff] exact match in snippet view article find links to article
• cellular response to DNA damage stimulus • chromatin organization • chromosome segregation • peptidyl-serine phosphorylation Sources:Amigo / QuickGO
Mad2 (1,128 words) [view diff] exact match in snippet view article find links to article
anaphase is called the spindle checkpoint. As a safeguard against chromosome segregation errors, the spindle assembly checkpoint (SAC) delays anaphase until
DDX3Y (845 words) [view diff] exact match in snippet view article find links to article
process • translational initiation • regulation of gene expression • RNA secondary structure unwinding • chromosome segregation Sources:Amigo / QuickGO
SRPK1 (1,450 words) [view diff] exact match in snippet view article find links to article
transduction • phosphorylation • regulation of mRNA processing • chromosome segregation • mRNA processing • regulation of mRNA splicing, via spliceosome
Polo-like kinase (1,469 words) [view diff] exact match in snippet view article find links to article
revealed that Polo kinases coordinate the more complex pattern of chromosome segregation in meiosis. Budding yeast Cdc5 is required in meiosis I for the
Nettie Stevens (2,529 words) [view diff] exact match in snippet view article find links to article
some species, chromosomes are different between the sexes and when chromosome segregation occurs in sperm formation, this difference leads to outcomes of
Wilms' tumor (2,697 words) [view diff] exact match in snippet view article find links to article
Sandstedt B, Meeker AK, Gisselsson D (November 2007). "Defective chromosome segregation and telomere dysfunction in aggressive Wilms' tumors". Clinical
Paleopolyploidy (2,921 words) [view diff] exact match in snippet view article find links to article
exploited in a laboratory setting by using colchicine to inhibit chromosome segregation during meiosis, creating synthetic autopolyploid plants.[citation
UBE2I (2,824 words) [view diff] exact match in snippet view article find links to article
Biological process • ubiquitin-dependent protein catabolic process • chromosome segregation • protein sumoylation • cell division • global genome nucleotide-excision
Zhimin Lu (1,855 words) [view diff] exact match in snippet view article find links to article
gene expression, the spindle assembly protein Bub3 to regulate chromosome segregation and mitotic checkpoint in metaphase, and myosin light chain (MLC)
DDX3X (1,779 words) [view diff] exact match in snippet view article find links to article
intrinsic apoptotic signaling pathway • immune system process • chromosome segregation • negative regulation of protein-containing complex assembly • response
Testis expressed 11 (364 words) [view diff] exact match in snippet view article find links to article
Biological process • fertilization • chiasma assembly • male meiosis chromosome segregation • synaptonemal complex assembly • resolution of meiotic recombination
RAD18 (1,640 words) [view diff] exact match in snippet view article find links to article
UV • negative regulation of cell death • positive regulation of chromosome segregation • DNA damage response, detection of DNA damage • cellular response
Pachygyria (2,538 words) [view diff] exact match in snippet view article find links to article
nucleokinesis, somal translocation, cell motility, mitosis, and chromosome segregation. LIS1 encodes for a 45kDa protein called PAFAH1B1 that contains
Aurora A kinase (2,719 words) [view diff] exact match in snippet view article find links to article
Aurora B kinase is a chromosome passenger protein and regulates chromosome segregation and cytokinesis. Although there is evidence to suggest that Aurora
CDC6 (1,370 words) [view diff] exact match in snippet view article find links to article
start control point of mitotic cell cycle • positive regulation of chromosome segregation • positive regulation of cyclin-dependent protein serine/threonine
Shugoshin N terminal protein domain (552 words) [view diff] exact match in snippet view article find links to article
(2009). "The many faces of shugoshin, the "guardian spirit," in chromosome segregation". Cell Cycle. 8 (1): 35–7. doi:10.4161/cc.8.1.7327. PMID 19106605
NDEL1 (1,318 words) [view diff] exact match in snippet view article find links to article
GO:0032861, GO:0032862, GO:0032856 activation of GTPase activity • chromosome segregation • neuron migration • positive regulation of axon regeneration •
Adenomatous polyposis coli (3,125 words) [view diff] exact match in snippet view article find links to article
(April 2001). "A role for the Adenomatous Polyposis Coli protein in chromosome segregation". Nature Cell Biology. 3 (4): 429–32. doi:10.1038/35070123. PMID 11283619
Cell growth (4,627 words) [view diff] exact match in snippet view article find links to article
reproduce by binary fission, a process that includes DNA replication, chromosome segregation, and cytokinesis. Eukaryotic cell division either involves mitosis
PSMC2 (2,566 words) [view diff] case mismatch in snippet view article find links to article
"Hec1p, an Evolutionarily Conserved Coiled-Coil Protein, Modulates Chromosome Segregation through Interaction with SMC Proteins". Mol. Cell. Biol. 19 (8):
Minichromosome maintenance (3,056 words) [view diff] exact match in snippet view article find links to article
subset of the minichromosomes. The former were mutants defective in chromosome segregation such as mcm16, mcm20 and mcm21. Among the latter class of origin-specific
Biorientation (479 words) [view diff] exact match in snippet view article find links to article
kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation". Journal of Cell Biology. 196: 757–774. doi:10.1083/jcb.201107124
Pyr1 (684 words) [view diff] exact match in snippet view article find links to article
mitosis: they generate the mitotic spindle assembly, which allows chromosome segregation and the cell division. Their stabilization leads to the inability
Condensin (7,280 words) [view diff] exact match in snippet view article find links to article
are not arrested at a specific stage of cell cycle, displaying chromosome segregation defects (i.e., anaphase bridges) and progressing through abnormal
Glucocorticoid receptor (3,831 words) [view diff] exact match in snippet view article find links to article
signaling pathway • cell cycle • cell division • apoptotic process • chromosome segregation • covalent chromatin modification • negative regulation of transcription
TOP1 (2,120 words) [view diff] exact match in snippet view article find links to article
• programmed cell death • phosphorylation • rhythmic process • chromosome segregation • protein sumoylation • circadian regulation of gene expression
Jason Swedlow (1,202 words) [view diff] exact match in snippet view article find links to article
Prof. Swedlow's research focuses on mechanisms and regulation of chromosome segregation during mitotic cell division and the development of software tools
ZC3H12B (1,010 words) [view diff] exact match in snippet view article find links to article
shift in protein N-terminal acetylation and is important for normal chromosome segregation". PLoS Genetics. 7 (7): e1002169. doi:10.1371/journal.pgen.1002169
Cell cycle (6,979 words) [view diff] exact match in snippet view article find links to article
(August 2006). "The Forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry
Holliday junction (3,840 words) [view diff] exact match in snippet view article find links to article
frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae". Genetics. 199 (2): 399–412. doi:10
Trisha Davis (950 words) [view diff] exact match in snippet view article find links to article
Schizosaccharomyces pombe and performs an essential function in chromosome segregation". Journal of Cell Science. 110 (15): 1805–1812. ISSN 0021-9533.
Anaphase lag (1,522 words) [view diff] case mismatch in snippet view article find links to article
Kinase Promotes Turnover of Kinetochore Microtubules to Reduce Chromosome Segregation Errors". Current Biology. 16 (17): 1711–1718. doi:10.1016/j.cub
Microtubule (7,372 words) [view diff] exact match in snippet view article find links to article
support, organization of the cytoplasm, transport, motility and chromosome segregation. In developing neurons microtubules are known as neurotubules, and
Deubiquitinating enzyme (4,246 words) [view diff] case mismatch in snippet view article find links to article
PMID 28920074. Potapova T, Gorbsky GJ (February 2017). "The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis". Biology. 6 (1): 12. doi:10.3390/biology6010012
N-alpha-acetyltransferase 10 (5,349 words) [view diff] exact match in snippet view article find links to article
shift in protein N-terminal acetylation and is important for normal chromosome segregation". PLOS Genetics. 7 (7): e1002169. doi:10.1371/journal.pgen.1002169
Karen Oegema (832 words) [view diff] exact match in snippet view article find links to article
proteins involved in the regulation of kinetochores and their role in chromosome segregation, known now as CENP-AHCP-3, CENP-CHCP-4 and KNL-3. American Society
Single-cell DNA template strand sequencing (3,370 words) [view diff] case mismatch in snippet view article find links to article
Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation". Stem Cells. 26 (11): 2964–2973. doi:10.1634/stemcells.2008-0634
Survivin (8,364 words) [view diff] exact match in snippet view article find links to article
death, but showed defects in mitosis characterized by improper chromosome segregation or failed cytokinesis. Deletion of particular IAPs does not seem
Stable nucleic acid lipid particle (2,190 words) [view diff] exact match in snippet view article find links to article
with phosphorylation of a variety of proteins and KSP integral to chromosome segregation during mitosis. Specifically, bipolar mitotic spindles are unable
TRIP13 (1,821 words) [view diff] exact match in snippet view article find links to article
was shown to be required for the meiotic checkpoint to prevent chromosome segregation when the recombination or chromosome synapsis are defective. TRIP13
ChIP-on-chip (2,934 words) [view diff] exact match in snippet view article find links to article
as well as factors involved in chromatin assembly/condensation, chromosome segregation, and the mitotic spindle checkpoint Other applications for ChIP-on-chip
Schizosaccharomyces pombe (5,908 words) [view diff] exact match in snippet view article find links to article
duplication, which takes place in S (Synthetic) phase, followed by chromosome segregation and nuclear division (mitosis) and cell division (cytokinesis),
Epigenetics (14,131 words) [view diff] exact match in snippet view article find links to article
Gammaproteobacteria, adenine methylation provides signals for DNA replication, chromosome segregation, mismatch repair, packaging of bacteriophage, transposase activity
CDC20 (3,290 words) [view diff] case mismatch in snippet view article find links to article
Brennan, Paul; Bolanos-Garcia, Victor M. (2020). "Deregulation of Chromosome Segregation and Cancer". Annual Review of Cancer Biology. 4: 257–278. doi:10
ATG5 (2,808 words) [view diff] exact match in snippet view article find links to article
translocating to the nucleus and interacting with survivin to disturb chromosome segregation by antagonistically competing with the ligand Aurora B. As a key
XMAP215-Dis1 family (2,170 words) [view diff] case mismatch in snippet view article find links to article
"Cdc2 Phosphorylation of the Fission Yeast Dis1 Ensures Accurate Chromosome Segregation". Current Biology. 16 (16): 1627–1635. doi:10.1016/j.cub.2006.06
Subtelomere (2,709 words) [view diff] exact match in snippet view article find links to article
functions with Shugoshin protein. Shugoshin is a centromere protein for chromosome segregation during meiosis and mitosis. There are two types of Shugoshin protein:
Holotomography (1,764 words) [view diff] exact match in snippet view article find links to article
"PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation". Nature Communications. 11 (1): 612. doi:10.1038/s41467-020-14511-w
Iron response element (1,985 words) [view diff] exact match in snippet view article find links to article
"Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation". Nature Cell Biology. 4 (4): 317–322. doi:10.1038/ncb777. PMID 11901424
ZGRF1 (1,677 words) [view diff] case mismatch in snippet view article find links to article
Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation". PLoS Genetics. 12 (6): e1006102. doi:10.1371/journal.pgen.1006102
Kinesin family member 11 (7,040 words) [view diff] exact match in snippet view article find links to article
via MHC class II • regulation of mitotic centrosome separation • chromosome segregation • GO:0043148 mitotic spindle organization • cell division • spindle
NAA15 (3,001 words) [view diff] exact match in snippet view article find links to article
shift in protein N-terminal acetylation and is important for normal chromosome segregation". PLOS Genetics. 7 (7): e1002169. doi:10.1371/journal.pgen.1002169
BRCA1 (14,025 words) [view diff] exact match in snippet view article find links to article
Biological process • response to ionizing radiation • centrosome cycle • chromosome segregation • protein K6-linked ubiquitination • intrinsic apoptotic signaling
Hybridogenesis in water frogs (2,680 words) [view diff] exact match in snippet view article find links to article
contain mixed parental genomes, as normally occurs by independent chromosome segregation and crossover in meiosis (see also second Mendel's law, recombination)
Actin (20,847 words) [view diff] exact match in snippet view article find links to article
to cell viability and they are involved in cell morphogenesis, chromosome segregation, and cell polarity. ParM is an actin homologue that is coded in
MIPOL1 (1,953 words) [view diff] exact match in snippet view article find links to article
found in this protein (see Fig.3): COG1196 at position 106 - 340 (Chromosome segregation ATPase) and COG4372 at 259 - 431 (uncharacterized conserved protein
DNA repair protein XRCC4 (5,687 words) [view diff] no match in snippet view article find links to article
able to map the human complementing gene to chromosome 5 using chromosome-segregation analysis. Giaccia et al, tentatively assigned this human gene the
TPX2 (4,950 words) [view diff] exact match in snippet view article find links to article
"Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation". Nature. 433 (7022): 171–6. Bibcode:2005Natur.433..171H. doi:10
Eukaryotic DNA replication (14,271 words) [view diff] exact match in snippet view article find links to article
that are still in the process of replication. In eukaryotic cells chromosome segregation into the daughter cells is not initiated until replication is complete