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are implicated in angiogenesis, pulmonary hypertension, cancer, and cardioprotection from ischemia-reperfusion injury. They exhibit an intracellular vesicularBW373U86 (501 words) [view diff] exact match in snippet view article find links to article
(August 2001). "BW373U86, a δ Opioid Agonist, Partially Mediates Delayed Cardioprotection via a Free Radical Mechanism that is Independent of Opioid ReceptorTAN-67 (550 words) [view diff] exact match in snippet view article find links to article
Fryer RM, Hsu AK, Nagase H, Gross GJ (August 2000). "Opioid-induced cardioprotection against myocardial infarction and arrhythmias: mitochondrial versusDexrazoxane (928 words) [view diff] exact match in snippet view article find links to article
doxorubicin or > 540 mg/m2 epirubicin and general approval for use for cardioprotection. That showed a possibly higher rate of secondary malignancies and acuteTyrosol (500 words) [view diff] exact match in snippet view article find links to article
Penumathsa SV, Paul D, Maulik N (2008). "Akt/FOXO3a/SIRT1-Mediated Cardioprotection by n-Tyrosol against Ischemic Stress in Rat in Vivo Model of MyocardialLipid emulsion (1,502 words) [view diff] exact match in snippet view article find links to article
potential cardioprotective agent Lou et al. (2014) found that the cardioprotection aspect of Intralipid is initiated by the accumulation of acylcarnitinesWine chemistry (1,256 words) [view diff] exact match in snippet view article find links to article
red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection". Journal of Pineal ResearchTeprenone (97 words) [view diff] exact match in snippet view article find links to article
S (September 2008). "Low-dose sevoflurane inhalation enhances late cardioprotection from the anti-ulcer drug geranylgeranylacetone". Anesth. Analg. 107Gerd Heusch (1,786 words) [view diff] exact match in snippet view article find links to article
2020, his long-term collaborator Petra Kleinbongard is professor for cardioprotection at the University of Duisburg-Essen Medical School since 2020. HeuschVDAC2 (2,675 words) [view diff] exact match in snippet view article find links to article
remove "unwanted" cells. The VDAC2 protein has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioningAdenosine receptor (2,074 words) [view diff] exact match in snippet view article find links to article
PMC 2423946. PMID 18537674. Peart JN, Headrick JP (May 2007). "Adenosinergic cardioprotection: multiple receptors, multiple pathways". Pharmacology & TherapeuticsSOD2 (3,223 words) [view diff] exact match in snippet view article find links to article
cardioprotective effects. In addition, SOD2 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioningVDAC3 (2,560 words) [view diff] exact match in snippet view article find links to article
remove "unwanted" cells. In addition, VDAC3 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioningRoberta Gottlieb (2,108 words) [view diff] exact match in snippet view article find links to article
mitochondria and mitochondrial biogenesis as essential elements of cardioprotection; efficient removal of damaged mitochondria is important for limitingRemote ischemic conditioning (7,021 words) [view diff] exact match in snippet view article find links to article
NEJM. October 5, 2015. Heusch, Gerd (2015-02-13). "Molecular Basis of Cardioprotection Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning"ERA-45 (371 words) [view diff] exact match in snippet view article find links to article
Tabor C, Black D, Ederveen A, Gray GA (2008). "Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptorAnkyrin-2 (3,443 words) [view diff] exact match in snippet view article find links to article
regulate cardiac ankyrin-B levels, and ankyrin-B is required for normal cardioprotection following ischemia reperfusion injury. ITPR1 HDJ1/HSP40 SPTBN1 OBSCNBAY 60–6583 (334 words) [view diff] exact match in snippet view article find links to article
Grenz A, Köhler D, Mittelbronn M, Ledent C, et al. (March 2007). "Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors". CirculationDiallyl trisulfide (866 words) [view diff] exact match in snippet view article find links to article
Bhushan, Shashi; Lefer, David J (2011). "Hydrogen sulfide-mediated cardioprotection: Mechanisms and therapeutic potential". Clinical Science. 120 (6):Nicorandil (869 words) [view diff] exact match in snippet view article find links to article
"Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?". Circulation. 97 (24): 2463–2469. doi:10.1161/01.cir.97.24.2463.SOD1 (3,632 words) [view diff] exact match in snippet view article find links to article
cardioprotective effects. In addition, SOD1 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioningFatty acid oxidation inhibitors (164 words) [view diff] exact match in snippet view article find links to article
biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". J. Cardiovasc. Pharmacol. 48 (6):Spermidine (1,433 words) [view diff] exact match in snippet view article find links to article
U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A (2016). "Cardioprotection and lifespan extension by the natural polyamine spermidine". NatureATP-sensitive potassium channel (2,579 words) [view diff] exact match in snippet view article find links to article
5-hydroxydecanoic acid ("5-HD") or MCC-134 completely inhibits the cardioprotection afforded by IPC, and genetic knockout of sarcKATP genes in mice hasIRF3 (1,493 words) [view diff] exact match in snippet view article find links to article
response as a potential therapeutic target for post-myocardial infarction cardioprotection. IRF3 has been shown to interact with IRF7. GRCh38: Ensembl releaseVK2735 (175 words) [view diff] exact match in snippet view article find links to article
peptide-1/glucose-dependent insulinotropic polypeptide receptor co-agonists for cardioprotection, type 2 diabetes and obesity: a review of mechanisms and clinical data"PER2 (1,760 words) [view diff] exact match in snippet view article find links to article
PER2 in turn enhances oxygen-efficient glycolysis and hence provides cardioprotection from ischemia. Therefore, it is speculated that strong light may reduceMelatonin (7,124 words) [view diff] exact match in snippet view article find links to article
red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection". Journal of Pineal ResearchCalorie restriction (2,653 words) [view diff] exact match in snippet view article find links to article
Carter CS, Leeuwenburgh C (November 2009). "Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives"Aspartate transaminase (2,115 words) [view diff] exact match in snippet view article find links to article
(September 2007). "The role of existing and novel cardiac biomarkers for cardioprotection". Current Opinion in Investigational Drugs. 8 (9): 711–717. PMID 17729182CGMP-specific phosphodiesterase type 5 (2,092 words) [view diff] exact match in snippet view article find links to article
(March 2018). "Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?". Heart. 104 (15). British Cardiac Society: 1244–1250. doi:10Hsp20 (579 words) [view diff] exact match in snippet view article find links to article
PMID 21853411. G.C, Fan; G, Chu; EG, Kranies (May 2005). "Hsp20 and its cardioprotection". Trends Cardiovasc. Med. 15 (4): 138–41. doi:10.1016/j.tcm.2005.05Thomas Pieber (453 words) [view diff] exact match in snippet view article find links to article
S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M. Cardioprotection and lifespan extension by the natural polyamine spermidine. NatureEpoxyeicosatrienoic acid (5,915 words) [view diff] exact match in snippet view article find links to article
Isbell MA, Falck JR, Gross GJ (Aug 2006). "Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury". American Journal of PhysiologyG protein-coupled receptor kinase (2,053 words) [view diff] exact match in snippet view article find links to article
137026 G protein-coupled receptor kinase 5 Polymorphism associated with cardioprotection GRK5 600870 G protein-coupled receptor kinase 6 Knockout mice are supersensitiveTroponin (3,597 words) [view diff] exact match in snippet view article find links to article
troponins as biomarkers of drug- and toxin-induced cardiac toxicity and cardioprotection". Expert Opin Drug Metab Toxicol. 1 (4): 715–25. doi:10.1517/17425255HRS9531 (181 words) [view diff] exact match in snippet view article find links to article
peptide-1/glucose-dependent insulinotropic polypeptide receptor co-agonists for cardioprotection, type 2 diabetes and obesity: a review of mechanisms and clinical data"Adenosine A3 receptor (2,128 words) [view diff] exact match in snippet view article find links to article
1998). "A physiological role of the adenosine A3 receptor: sustained cardioprotection". Proceedings of the National Academy of Sciences of the United StatesHomeobox protein Nkx-2.5 (2,325 words) [view diff] exact match in snippet view article find links to article
profoundly involved in the generation of cardiac hypertrophy or in cardioprotection from cytotoxic stress in the adult heart. The NKX2-5 transcriptionSandra M. Swain (1,450 words) [view diff] exact match in snippet view article find links to article
E. Velez-Garcia, M. S. Ewer, J. R. Bianchine & R. A. Gams (1997). "Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breastAdenosine deaminase (2,965 words) [view diff] exact match in snippet view article find links to article
during ischemic stress". HIF-1α in the Heart: Provision of Ischemic Cardioprotection and Remodeling of Nucleotide Metabolism (PDF) (PhD). Electronic ThesesHSPB6 (750 words) [view diff] exact match in snippet view article find links to article
PMID 18579210. Fan GC, Chu G, Kranias EG (May 2005). "Hsp20 and its cardioprotection". Trends Cardiovasc. Med. 15 (4): 138–41. doi:10.1016/j.tcm.2005.05Δ-opioid receptor (3,262 words) [view diff] exact match in snippet view article find links to article
the rat model, introduction of DOR ligands results in significant cardioprotection. Until comparatively recently, there were few pharmacological toolsReperfusion injury (3,212 words) [view diff] exact match in snippet view article find links to article
as an Endpoint to Initiate Cell Death and as a Putative Target for Cardioprotection". Cellular Physiology and Biochemistry. 20 (1–4): 1–22. doi:10.1159/000103747Δ-opioid receptor (3,262 words) [view diff] exact match in snippet view article find links to article
the rat model, introduction of DOR ligands results in significant cardioprotection. Until comparatively recently, there were few pharmacological toolsBilophila wadsworthia (1,055 words) [view diff] exact match in snippet view article find links to article
there are some benefits to hydrogen sulfide production in the gut like cardioprotection, hydrogen sulfide production also contributes to disease pathologyGingerol (2,832 words) [view diff] exact match in snippet view article find links to article
Elberry AA, Ghareib SA, Azhar A, Banjar ZM, Watson ML (September 2016). "Cardioprotection by 6-gingerol in diabetic rats". Biochemical and Biophysical ResearchMitochondrial permeability transition pore (3,448 words) [view diff] exact match in snippet view article find links to article
permeability transition pore: molecular nature and role as a target in cardioprotection". Journal of Molecular and Cellular Cardiology. 78: 100–106. doi:10Intermittent fasting (6,656 words) [view diff] exact match in snippet view article find links to article
"Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial"Mir-1 microRNA precursor family (3,291 words) [view diff] exact match in snippet view article find links to article
rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection". Cardiovascular Research. 84 (3): 434–41. doi:10.1093/cvr/cvp232.NOL3 (1,190 words) [view diff] exact match in snippet view article find links to article
"Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress". Circulation. 113PPIC (1,387 words) [view diff] exact match in snippet view article find links to article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Similarly, PPIC may confer neuroprotectionIntracrine (2,687 words) [view diff] exact match in snippet view article find links to article
differentiation. The intracrine actions of VEGF have been implicated in cardioprotection, particularly in response to ischemic stress. Cardiac myocytes exposedPPIE (gene) (1,043 words) [view diff] exact match in snippet view article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expressionCiclosporin (5,376 words) [view diff] exact match in snippet view article find links to article
NeuroVive's formulation of ciclosporin called Neurostat (also known by its cardioprotection brand name of Ciclomulsion). This formulation uses a lipid emulsionPerfluorocarbon emulsions (2,213 words) [view diff] exact match in snippet view article find links to article
Unger, Evan C.; Martin, Diego R. (March 2019). "Imaging assessment of cardioprotection mediated by a dodecafluoropentane oxygen-carrier administered duringSodium nitroprusside (4,068 words) [view diff] exact match in snippet view article find links to article
Guanosine Monophosphate Signaling and Phosphodiesterase-5 Inhibitors in Cardioprotection". Journal of the American College of Cardiology. 59 (22): 1921–1927Forsythoside B (548 words) [view diff] exact match in snippet view article find links to article
PMID 8593444. Jiang WL, Fu FH, Xu BM, Tian JW, Zhu HB (July 2010). "Cardioprotection with forsythoside B in rat myocardial ischemia-reperfusion injury:Platelet (8,530 words) [view diff] exact match in snippet view article find links to article
"Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection". Seminars in Thrombosis and Hemostasis. 31 (2): 234–246. doi:10.1055/s-2005-869528Senescence (7,177 words) [view diff] exact match in snippet view article find links to article
O'Keefe JH, DiNicolantonio JJ, Lavie CJ (1 May 2018). "Coffee for Cardioprotection and Longevity". Progress in Cardiovascular Diseases. 61 (1): 38–42HMR 1883 (901 words) [view diff] exact match in snippet view article find links to article
, & Marban, E. (2000). The role of mitochondrial KATP channels in cardioprotection. Bas Res Cardiol 95, 285−289 Bohn, H., Englert, H. C., & SchoelkensDieting (6,619 words) [view diff] exact match in snippet view article find links to article
alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults". The American Journal of Clinical Nutrition. 90 (5):Peptidylprolyl isomerase A (1,588 words) [view diff] exact match in snippet view article find links to article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, PPIA expression is highlyAntiporter (7,840 words) [view diff] exact match in snippet view article find links to article
(2015-03-31). Faculty Opinions recommendation of Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioningAdenosine monophosphate deaminase deficiency type 1 (4,691 words) [view diff] exact match in snippet view article find links to article
Skalova, K; Luptak, I; Turcani, M; Hulin, I (2002). "Adenosine and cardioprotection: what can we learn from nature's genetic polymorphism?" (PDF). BratislavskeTopoisomerase (6,181 words) [view diff] exact match in snippet view article find links to article
Cvetković RS, Scott LJ (2005). "Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy". Drugs. 65 (7): 1005–1024. doi:10Tracy L. Johnson (4,233 words) [view diff] exact match in snippet view article find links to article
DeAntonio, J. H., Thayne, K., Ding, J. M., & Lust, R. M. (2013). Cardioprotection via preserved mitochondrial structure and function in the mPer2-mutantHanoch Senderowitz (1,512 words) [view diff] exact match in snippet view article find links to article
1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model". Journal of Medicinal ChemistryPPIF (1,594 words) [view diff] exact match in snippet view article find links to article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expressionMAPK14 (5,270 words) [view diff] exact match in snippet view article find links to article
chronic insulin stimulation. Inhibition of p38 MAPK activity confers cardioprotection against ischemia reperfusion injury in heart However, some reportsCaloric restriction mimetic (2,847 words) [view diff] exact match in snippet view article find links to article
Tobias; Harger, Alexandra; Schipke, Julia; Zimmermann, Andreas (2016). "Cardioprotection and lifespan extension by the natural polyamine spermidine". NaturePeptidylprolyl isomerase D (1,678 words) [view diff] exact match in snippet view article find links to article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expressionABT-702 (568 words) [view diff] exact match in snippet view article find links to article
"An adenosinergic positive feedback loop extends pharmacological cardioprotection duration". British Journal of Pharmacology. 181 (23): 4920–4936. doi:10Hepatocyte growth factor receptor (6,731 words) [view diff] exact match in snippet view article find links to article
channels. In the injured heart, HGF/MET axis plays important roles in cardioprotection by promoting pro-survival (anti-apoptotic and anti-autophagic) effectsGamma-butyrobetaine dioxygenase (2,772 words) [view diff] exact match in snippet view article find links to article
biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". Journal of Cardiovascular PharmacologyAlpha-ketoglutarate-dependent hydroxylases (3,976 words) [view diff] exact match in snippet view article find links to article
biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". Journal of Cardiovascular PharmacologyPPIB (2,598 words) [view diff] exact match in snippet view article find links to article
complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. PPIB contributes to the replicationHistone acetylation and deacetylation (7,036 words) [view diff] exact match in snippet view article find links to article
Stanmore DA, Backs J (May 2014). "Histone deacetylase signaling in cardioprotection". Cellular and Molecular Life Sciences. 71 (9): 1673–90. doi:10Influenza vaccine (18,986 words) [view diff] exact match in snippet view article find links to article
JA (January 13, 2022). "Universal flu vaccines: a shot at lifelong cardioprotection?". Nature Reviews Cardiology. 19 (3): 145–146. doi:10.1038/s41569-021-00670-wPurinergic signalling (5,964 words) [view diff] exact match in snippet view article find links to article
McIntosh VJ, Lasley RD (March 2012). "Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?". Journal of Cardiovascular