Find link

language:

jump to random article

Find link is a tool written by Edward Betts.

searching for CYP2C9 29 found (183 total)

alternate case: cYP2C9

Tienilic acid (614 words) [view diff] exact match in snippet view article find links to article

had liver failure after taking this drug contained antibodies recognizing CYP2C9 able to hydroxylate the drug and to give covalent binding. The above explanation
Tecarfarin (514 words) [view diff] exact match in snippet view article find links to article
warfarin patients (pint=0.16); among patients who had both a CYP2C9 variant allele and taking a CYP2C9 interacting drug, TTR was 76.5% and 69.5% for the tecarfarin
Gliclazide (1,259 words) [view diff] exact match in snippet view article find links to article
in human beings, mainly methylhydroxygliclazide and carboxygliclazide. CYP2C9 is involved in the formation of hydroxygliclazide in human liver microsomes
Cooperstown cocktail (342 words) [view diff] exact match in snippet view article find links to article
Warfarin (actually the S-warfarin enantiomer) is a specific probe for CYP2C9. The '+ 1' refers to the vitamin K that is given together with the warfarin
Flavones (565 words) [view diff] exact match in snippet view article find links to article
Oct;7(7):729-44. Si D, Wang Y, Zhou YH, et al. (March 2009). "Mechanism of CYP2C9 inhibition by flavones and flavonols". Drug Metab. Dispos. 37 (3): 629–34
Lobeglitazone (579 words) [view diff] exact match in snippet view article find links to article
South Korea Pharmacokinetic data Protein binding >99% Metabolism liver (CYP2C9, 2C19, and 1A2) Elimination half-life 7.8–9.8 hours Identifiers IUPAC name
Umbralisib (768 words) [view diff] exact match in snippet view article find links to article
None Legal status Legal status US: ℞-only Pharmacokinetic data Metabolism CYP2C9, CYP3A4, and CYP1A2 Elimination half-life 91 h Excretion Feces, urine Identifiers
Aconitine (3,342 words) [view diff] exact match in snippet view article find links to article
16-O-Demethyl-aconitine CYP3A4, CYP3A5, CYP2D6, CYP2C9 M3 N-deethyl-aconitine CYP3A4, CYP3A5, CYP2D6, CYP2C9 M4 O-didemethyl-aconitine CYP3A5, CYP2D6 M5
Coronaric acid (1,124 words) [view diff] exact match in snippet view article find links to article
linoleic acid by cytochrome P450 (CYP) epoxygenase enzymes. These CYPs (CYP2C9 and probably other CYPs that metabolize polyunsaturated fatty acids to epoxides)
Piroxicam (795 words) [view diff] exact match in snippet view article find links to article
Rheumatology. 4 (4): 393–404. PMID 342691. Dean L (2019). "Piroxicam Therapy and CYP2C9 Genotype". In Pratt VM, McLeod HL, Rubinstein WS, et al. (eds.). Medical
Robert J. Desnick (3,039 words) [view diff] exact match in snippet view article find links to article
PMID 17533632 Scott, SA, Edelmann, L, Kornreich, R, Erazo, M and Desnick, RJ: CYP2C9, CYP2C19, and CYP2D6 allele frequencies in the Ashkenazi Jewish population
Rifapentine (961 words) [view diff] exact match in snippet view article find links to article
rifampicin and rifabutin. Rifapentine induces metabolism by CYP3A4, CYP2C8 and CYP2C9 enzymes. It may be necessary to adjust the dosage of drugs metabolized by
Butabarbital (1,491 words) [view diff] exact match in snippet view article find links to article
Half-Life: ~100 hr Duration: 6-8 hr Onset: 45-60 min Enzymes induced: CYP1A2, CYP2C9/10, CYP3A4 Excretion: Urine The mechanism of action by which barbiturates
Lacosamide (3,388 words) [view diff] exact match in snippet view article find links to article
is eliminated in the feces. The major metabolic pathway of lacosamide is CYP2C9, CY2C19, and CYP3A4-mediated demethylation. The dose-response curve for
Prasugrel (2,101 words) [view diff] exact match in snippet view article find links to article
which is then converted by CYP3A4 and CYP2B6, and to a minor extent by CYP2C9 and CYP2C19, to a pharmacologically active metabolite (R-138727). R-138727
Constitutive androstane receptor (2,229 words) [view diff] exact match in snippet view article find links to article
LeCluyse EL, Negishi M, Goldstein JA (Sep 2002). "Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding
Moxifloxacin (3,129 words) [view diff] exact match in snippet view article find links to article
enzymes indicate that moxifloxacin does not inhibit 80 CYP3A4, CYP2D6, CYP2C9, CYP2C19, or CYP1A2, suggesting that moxifloxacin is unlikely to alter the
Medical cannabis (10,181 words) [view diff] exact match in snippet view article find links to article
rather than by urine. After delta-9-THC is hydroxylated into 11-OH-THC via CYP2C9, CYP2C19, and CYP3A4, it undergoes phase II metabolism into more than 30
Ritonavir (2,181 words) [view diff] exact match in snippet view article find links to article
concentrations of oxycodone; phenytoin—induction of phenytoin metabolism by CYP2C9;[medical citation needed] pimozide;[medical citation needed] quinidine;[medical
ALDH1A1 (1,459 words) [view diff] exact match in snippet view article find links to article
2008). "Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics
Discovery and development of cyclooxygenase 2 inhibitors (4,441 words) [view diff] exact match in snippet view article find links to article
oral doses, between 100 and 800 mg. Celecoxib is metabolized primarily by CYP2C9 isoenzyme to carboxylic acid and also by non-CYP-dependent glucuronidation
Single-nucleotide polymorphism (5,149 words) [view diff] exact match in snippet view article find links to article
0306-5251.2001.01499.x. PMC 2014584. PMID 11678778. Lee CR (July–August 2004). "CYP2C9 genotype as a predictor of drug disposition in humans". Methods and Findings
Personalized medicine (6,585 words) [view diff] exact match in snippet view article find links to article
prescribed drugs. However, with the discovery of polymorphic variants in CYP2C9 and VKORC1 genotypes, two genes that encode the individual anticoagulant
Ketamine (9,933 words) [view diff] exact match in snippet view article find links to article
Hijazi Y, Boulieu R (July 2002). "Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes". Drug
Blidy (2,220 words) [view diff] exact match in snippet view article find links to article
carbon monoxide. There are more than 50 CYP450 enzymes, but the CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 enzymes metabolize 90 percent of drugs
Eicosanoid (9,521 words) [view diff] exact match in snippet view article find links to article
The human cytochrome P450 (CYP) epoxygenases, CYP1A1, CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, and CYP2S1 metabolize arachidonic acid
Elagolix (5,978 words) [view diff] exact match in snippet view article find links to article
fluconazole (a strong inhibitor of CYP2C19 and a moderate inhibitor of CYP2C9 and CYP3A4). Elagolix is a substrate of the hepatic OATP1B1 transporter
Jonathan L. Halperin (1,719 words) [view diff] exact match in snippet view article find links to article
Kornreich, Ruth; Halperin, Jonathan L; Desnick, Robert J (August 2009). "CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic
Cornelia Ulrich (1,015 words) [view diff] exact match in snippet view article find links to article
Robert S.; McKeown-Eyssen, Gail E.; Ulrich, Cornelia M. (August 29, 2015). "CYP2C9 Variants Increase Risk of Colorectal Adenoma Recurrence and Modify Associations