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searching for CYP2B6 22 found (92 total)

alternate case: cYP2B6

Constitutive androstane receptor (2,238 words) [view diff] exact match in snippet view article find links to article

Pascussi JM, Porrogi P, et al. (2007). "Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor". Drug Metab. Dispos. 35 (9):
Bromazolam (1,994 words) [view diff] exact match in snippet view article find links to article
bromazolam was catalysed by CYP2B6, CYP2C19, and CYP3A4. 4-hydroxy bromazolam, as well as α-hydroxy bromazolam, were formed by CYP2B6, CYP2C19, CYP3A4, and
Lumefantrine (1,242 words) [view diff] exact match in snippet view article find links to article
07.013. PMID 32921396. Zakaria Z, Badhan RK (July 2018). "The impact of CYP2B6 polymorphisms on the interactions of efavirenz with lumefantrine: Implications
Chlorethoxyfos (1,945 words) [view diff] exact match in snippet view article find links to article
important enzymes in metabolism of organophosphorus compounds are CYP1A1, CYP2B6, CYP3A4 and CYP2C19. The first three cytochromes catalyze the oxidative
Ticlopidine (1,724 words) [view diff] exact match in snippet view article find links to article
decreases the absorption of ticlopidine. Ticlopidine inhibits liver CYP2C19 and CYP2B6 and thus can affect blood levels of medications metabolized by these systems
Pregnane X receptor (1,978 words) [view diff] exact match in snippet view article find links to article
expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels". Drug Metabolism and Disposition. 31 (1): 7–10. doi:10.1124/dmd
Levomethadone (987 words) [view diff] exact match in snippet view article find links to article
Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers". Clinical Pharmacology and Therapeutics. 81 (5): 719–728
Prasugrel (2,024 words) [view diff] exact match in snippet view article find links to article
a likewise inactive thiolactone, which is then converted by CYP3A4 and CYP2B6, and to a minor extent by CYP2C9 and CYP2C19, to a pharmacologically active
UGT2B7 (3,244 words) [view diff] exact match in snippet view article find links to article
PMID 19956635. Kwara A, Lartey M, Sagoe KW, Kenu E, Court MH (October 2009). "CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose
Ilya B. Tsyrlov (1,341 words) [view diff] exact match in snippet view article find links to article
Following up discovery of mechanism for “phenobarbital-type” induction of CYP2B6 and applicability of induced-fit hypothesis for membrane-bound enzymes,
Norketamine (1,150 words) [view diff] exact match in snippet view article find links to article
metabolized by the superfamily of cytochrome P450 enzymes, particularly CYP2B6 and CYP3A. Though these enzymes are predominantly found in the liver, they
Ilya B. Tsyrlov (1,341 words) [view diff] exact match in snippet view article find links to article
Following up discovery of mechanism for “phenobarbital-type” induction of CYP2B6 and applicability of induced-fit hypothesis for membrane-bound enzymes,
Women's Interagency HIV Study (1,235 words) [view diff] exact match in snippet view article find links to article
Aouizerat, Bradley (1 November 2012). "A Single-Nucleotide Polymorphism in CYP2B6 Leads to >3-Fold Increases in Efavirenz Concentrations in Plasma and Hair
Abrocitinib (2,670 words) [view diff] exact match in snippet view article find links to article
by cytochrome P450 (CYP450) in liver such as CYP2C9, CYP2C19, CYP3A4 and CYP2B6. The major metabolites of abrocitinib are pyrrolidinone pyrimidine (inactive)
Sibutramine (3,661 words) [view diff] exact match in snippet view article find links to article
Retrieved 2007-04-29. Kim KA, Song WK, Park JY (November 2009). "Association of CYP2B6, CYP3A5, and CYP2C19 genetic polymorphisms with sibutramine pharmacokinetics
Metamizole (4,766 words) [view diff] exact match in snippet view article find links to article
arachidonoyl-4-aminoantipyrine (ARA-4-AA). Metamizole likely induces the CYP2B6 and CYP3A4 enzymes. Ludwig Knorr was a student of Emil Fischer, who won
Serotonin–dopamine reuptake inhibitor (1,782 words) [view diff] exact match in snippet view article find links to article
PMID 19689361. Kim, K A; Song, W K; Park, J Y (2009). "Association of CYP2B6, CYP3A5, and CYP2C19 Genetic Polymorphisms With Sibutramine Pharmacokinetics
ALDH1A1 (2,590 words) [view diff] exact match in snippet view article find links to article
(June 2008). "Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on
Development and discovery of SSRI drugs (5,336 words) [view diff] exact match in snippet view article find links to article
determined in humans 20 98 25–26 hours Extensive first-pass hepatic primarily by CYP2B6 Desmethyl-sertraline (limited activity) Faeces and urine in equal amount
Serotonin–norepinephrine–dopamine reuptake inhibitor (16,223 words) [view diff] exact match in snippet view article find links to article
Switzerland AG. Kim, K A; Song, W K; Park, J Y (2009). "Association of CYP2B6, CYP3A5, and CYP2C19 Genetic Polymorphisms With Sibutramine Pharmacokinetics
HepaRG (2,666 words) [view diff] exact match in snippet view article find links to article
factors. They also possess functional levels of phase I (CYP (CYP1A1/2, CYP2B6, CYP2Cs, CYP3A4, etc.) and II (UGT1A1, GSTA1, GSTA4, GSTM1) drug metabolizing
Evolutionary models of human drug use (6,484 words) [view diff] exact match in snippet view article find links to article
neurotoxins. The ubiquity of CYP genes in humans worldwide, including CYP2A6 and CYP2B6, which metabolize nicotine, as well as other drugs, might suggest an evolutionary