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Longer titles found: Multiple c2 domains, transmembrane 2 (view)

searching for C2 domain 64 found (139 total)

alternate case: c2 domain

CC2D2A (611 words) [view diff] exact match in snippet view article find links to article

Coiled-coil and C2 domain-containing protein 2A that in humans is encoded by the CC2D2A gene. This gene encodes a coiled-coil and calcium binding domain

SYT1 (1,503 words) [view diff] exact match in snippet view article find links to article

Südhof TC, Rizo J (Jan 1997). "Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch". Neuron. 18 (1): 133–42. doi:10

Factor VIII (2,001 words) [view diff] exact match in snippet view article find links to article

domains belong to the phospholipid-binding discoidin domain family, and the C2 domain mediate membrane binding. Activation of factor VIII to factor VIIIa is

PIK3C2G (989 words) [view diff] exact match in snippet view article find links to article

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide is an enzyme that in humans is encoded by the PIK3C2G gene. The protein

PIK3C2B (1,114 words) [view diff] exact match in snippet view article find links to article

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide is an enzyme that in humans is encoded by the PIK3C2B gene. The protein

CC2D1A (612 words) [view diff] exact match in snippet view article find links to article

Coiled-coil and C2 domain-containing protein 1A is a protein that in humans is encoded by the CC2D1A gene. GRCh38: Ensembl release 89: ENSG00000132024

Brain-specific angiogenesis inhibitor 1 (1,207 words) [view diff] exact match in snippet view article find links to article

"Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochemical and Biophysical

Lysophospholipase (692 words) [view diff] exact match in snippet view article find links to article

phospholipase B (EC 3.1.1.5) and cytosolic phospholipase A2 which also has a C2 domain InterPro: IPR000008. Phospholipase B enzymes catalyse the release of fatty

PRKCD (1,096 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1bdy: C2 DOMAIN FROM PROTEIN KINASE C DELTA 1ptq: PROTEIN KINASE C DELTA CYS2 DOMAIN 1ptr: PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED

RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article

tissues. RasGAP contains one SH3 domain and two SH2 domains, a PH domain, a C2 domain, and a GAP domain. RAS p21 protein activator 1 has been shown to interact

Phosphatidylinositol-4-phosphate 3-kinase (196 words) [view diff] no match in snippet view article find links to article

Other names in common use include type II phosphoinositide 3-kinase, C2-domain-containing phosphoinositide 3-kinase, and phosphoinositide 3-kinase. This

NEDD4L (3,265 words) [view diff] exact match in snippet view article find links to article

heart and the kidney contains a C2 domain. Three predominant forms of NEDD4L are isoform I containing a novel C2 domain with a start codon in exon1, isoform

Extended synaptotagmin-2 (463 words) [view diff] exact match in snippet view article find links to article

(Sep 2007). "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans"

NEDD4 (3,414 words) [view diff] exact match in snippet view article find links to article

and a carboxyl-terminal catalytic HECT ubiquitin ligase domain. The C2 domain targets proteins to the phospholipid membrane, and can also be involved

SYT13 (503 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1wfm: The first C2 domain of human synaptotagmin XIII

Annexin A6 (1,264 words) [view diff] exact match in snippet view article find links to article

"Mapping the site of interaction between annexin VI and the p120GAP C2 domain". FEBS Letters. 460 (1): 166–72. doi:10.1016/S0014-5793(99)01336-8. PMID 10571081

SYT4 (492 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1ugk: Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342) 1w15: RAT SYNAPTOTAGMIN 4 C2B

SYT7 (553 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 2d8k: Solution structure of the first C2 domain of synaptotagmin VII

Syndecan-4 (2,088 words) [view diff] exact match in snippet view article find links to article

– actin-association cytoskeleton Variable domain – syndecan-specific C2 domain – attach to PDZ proteins Syndecans normally form homodimers or multimers

CDCP1 (1,079 words) [view diff] exact match in snippet view article find links to article

CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP (April 2005). "The C2 domain of PKCdelta is a phosphotyrosine binding domain". Cell. 121 (2): 271–80

Extended synaptotagmin-1 (488 words) [view diff] exact match in snippet view article find links to article

(Sep 2007). "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans"

PRKCE (6,268 words) [view diff] exact match in snippet view article find links to article

have preferred affinity to the (RACK/RACK2) isoform; specifically, the C2 domain of PKCε at amino acids 14–21 (also known as εV1-2) binds (RACK/RACK2)

STX1A (2,987 words) [view diff] exact match in snippet view article find links to article

Südhof TC, Rizo J (January 1997). "Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch". Neuron. 18 (1): 133–42. doi:10

PRKCG (526 words) [view diff] case mismatch in snippet view article find links to article

NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, 30 STRUCTURES 2uzp: CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN PROTEIN KINASE C GAMMA.

Exocytosis (1,782 words) [view diff] no match in snippet view article find links to article

calcium sensors for exocytosis are EF-hand proteins (Ex: Calmodulin) and C2-domain (Ex: Ferlins, E-synaptotagmin, Doc2b) containing proteins. It is unclear

WWC1 (1,113 words) [view diff] exact match in snippet view article find links to article

1016/S0006-291X(02)02945-5. PMID 12559952. "Entrez Gene: WWC1 WW and C2 domain containing 1". "dbSNP: rs17070145". Need AC, Attix DK, McEvoy JM, Cirulli

PRKCB1 (675 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1a25: C2 DOMAIN FROM PROTEIN KINASE C (BETA) 2i0e: Structure of catalytic domain of human protein kinase C beta II complexed with a

Annexin A13 (616 words) [view diff] exact match in snippet view article find links to article

"Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb". The Journal of Cell Biology. 149 (7): 1473–84. doi:10

SMURF1 (1,916 words) [view diff] exact match in snippet view article find links to article

that include an N-terminal C2 domain, two to three WW domains containing tryptophan residues, and an HECT domain. The C2 domain plays a crucial role in mediating

SYTL2 (1,265 words) [view diff] exact match in snippet view article find links to article

by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein

Dephosphorylation (2,174 words) [view diff] exact match in snippet view article find links to article

phosphatase and tensin homolog (PTEN). The active site of the blue N-terminal phosphatase domain is shown in yellow. The C-terminal C2 domain is shown in red.

Annexin A4 (1,046 words) [view diff] exact match in snippet view article find links to article

novel protein complex containing annexin VI, Fyn, Pyk2, and the p120(GAP) C2 domain". FEBS Letters. 469 (1): 88–92. doi:10.1016/S0014-5793(00)01252-7. PMID 10708762

CD48 (2,192 words) [view diff] no match in snippet view article find links to article

the 4 domains of CD48: signal peptide, variable (V) domain, constant 2 (C2) domain and the glycophosphatidylinositol anchor (GPI anchor). The cDNA sequence

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (1,005 words) [view diff] case mismatch in snippet view article find links to article

"Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module". Molecular Cell. 71 (2): 343–351.e4. doi:10.1016/j.molcel.2018

PTK2B (1,887 words) [view diff] exact match in snippet view article find links to article

novel protein complex containing annexin VI, Fyn, Pyk2, and the p120(GAP) C2 domain". FEBS Lett. 469 (1): 88–92. doi:10.1016/s0014-5793(00)01252-7. PMID 10708762

Phosphoinositide 3-kinase (3,463 words) [view diff] exact match in snippet view article find links to article

and function. The distinct feature of Class II PI3Ks is the C-terminal C2 domain. This domain lacks critical Asp residues to coordinate binding of Ca2+

Bacterial initiation factor (2,501 words) [view diff] exact match in snippet view article find links to article

the initiator fMet-tRNA to the P-site of the 30S ribosomal subunit. The C2 domain of IF2 has a unique recognition and binding affinity towards the initiator

PKC alpha (2,643 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1dsy: C2 DOMAIN FROM PROTEIN KINASE C (ALPHA) COMPLEXED WITH CA2+ AND PHOSPHATIDYLSERINE

DOC2A (445 words) [view diff] exact match in snippet view article find links to article

DOC2A Identifiers Aliases DOC2A, Doc2, double C2 domain alpha External IDs OMIM: 604567; MGI: 109446; HomoloGene: 2657; GeneCards: DOC2A; OMA:DOC2A -

SYTL1 (555 words) [view diff] exact match in snippet view article find links to article

Johnson JL, Ruedi JM, Thon V, Babior BM (June 2001). "JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase". The Journal

TC2N (369 words) [view diff] exact match in snippet view article find links to article

PMID 11526914. S2CID 33045301. "Entrez Gene: MTAC2D1 membrane targeting (tandem) C2 domain containing 1". Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The

CPNE4 (418 words) [view diff] exact match in snippet view article find links to article

Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved

PLA2G4A (1,023 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1bci: C2 DOMAIN OF CYTOSOLIC PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE 1cjy: HUMAN CYTOSOLIC PHOSPHOLIPASE A2 1rlw: CALCIUM-PHOSPHOLIPID

TOLLIP (1,283 words) [view diff] exact match in snippet view article find links to article

subcellular membrane compartments such as endosome and lysosome through its C2 domain binding with phosphoinositides. By coordinating organelle communications

ADCY2 (1,512 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1ab8: RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX 1azs: COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL

RIMS2 (828 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1v27: Solution structure of the first C2 domain of RIM2 1wfg: PDZ domain of human RIM2B 2bwq: CRYSTAL STRUCTURE OF THE RIM2 C2A-DOMAIN

CPNE8 (541 words) [view diff] exact match in snippet view article find links to article

Tomsig JL, Snyder SL, et al. (1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved

DOC2B (877 words) [view diff] exact match in snippet view article find links to article

DOC2B Identifiers Aliases DOC2B, DOC2BL, double C2 domain beta External IDs OMIM: 604568; MGI: 1100497; HomoloGene: 20796; GeneCards: DOC2B; OMA:DOC2B

OS9 (gene) (770 words) [view diff] exact match in snippet view article

1999). "Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified

BAIAP3 (689 words) [view diff] exact match in snippet view article find links to article

"Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochem Biophys Res Commun

SMURF2 (1,326 words) [view diff] exact match in snippet view article find links to article

"Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain". Cell. 130 (4): 651–62. doi:10.1016/j.cell.2007.06.050. PMID 17719543

Multilateral Interoperability Programme (848 words) [view diff] exact match in snippet view article find links to article

the taxonomic and semantic foundation for information exchange in the C2 domain. The goal is to harmonize current information exchange concepts and create

Multimerin 1 (899 words) [view diff] exact match in snippet view article find links to article

et al. (2005). "Identification of the MMRN1 binding region within the C2 domain of human factor V". J. Biol. Chem. 279 (49): 51466–71. doi:10.1074/jbc

Ram Rajasekharan (2,486 words) [view diff] exact match in snippet view article find links to article

PMC 3265875. PMID 22128159. Rupwate, Sunny D; Rajasekharan, Ram (2011). "C2 domain is responsible for targeting rice phosphoinositide specific phospholipase

RAB11FIP5 (1,583 words) [view diff] exact match in snippet view article find links to article

Jiang S, Mitok KA, Li L, Attie AD, Martin TFJ (July 2017). "BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in

PASLI disease (1,244 words) [view diff] exact match in snippet view article find links to article

1): adaptor-binding domain, a Ras GTPase-binding domain, a PI(3)K-type C2 domain, helical domain, and a kinase domain. Mutations have been identified in

George J. Augustine (729 words) [view diff] no match in snippet view article find links to article

Augustine, George J. (1993). "Inhibition of Neurotransmitter Release by C2-domain Peptides Implicates Synaptotagmin in Exocytosis". Nature. 363 (6425):

PLCG1 (3,774 words) [view diff] exact match in snippet view article find links to article

X and Y catalytic region comprising the TIM barrel; and a C-terminal C2 domain. Specific to the PLCG isozymes is a large separation between the X and

Plasmodium falciparum erythrocyte membrane protein 1 (6,604 words) [view diff] exact match in snippet view article find links to article

highly variable Duffy-binding-like (DBL) domain, sometimes a Ca2+-binding C2 domain, and then one or two cysteine-rich interdomain regions (CIDRs). Duffy-binding-like

CPNE1 (1,863 words) [view diff] exact match in snippet view article find links to article

F, Beisson J, Cohen J (January 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved

Prothrombinase (3,112 words) [view diff] exact match in snippet view article find links to article

(January 2005). "The phosphatidylserine binding site of the factor Va C2 domain accounts for membrane binding but does not contribute to the assembly

Voltage sensitive phosphatase (2,191 words) [view diff] exact match in snippet view article find links to article

voltage sensor domain, and a phosphatase domain coupled to a lipid-binding C2 domain. The voltage sensor domain contains four transmembrane helices, named

C13orf38 (842 words) [view diff] exact match in snippet view article find links to article

1-acylglycerol-3-phosphate O-acyltransferases 0.471 BAIAP3 BAI1 associated protein 3; C2 domain containing 0.708 CLMP CXADR-like membrane protein; May be involved in

LRDD (5,966 words) [view diff] exact match in snippet view article find links to article

PIDDosome signaling: centrosomal protein 20 (CEP20, also known as FOPNL), C2 domain-containing protein 3 (C2CD3), which is involved in centriole elongation