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searching for Anthracycline 41 found (138 total)

EPOCH (chemotherapy) (684 words) [view diff] exact match in snippet view article

antineoplastic agent; Hydroxydaunorubicin, also known as doxorubicin: an anthracycline antibiotic that is able to intercalate DNA, damaging it and preventing

MINE (chemotherapy) (147 words) [view diff] exact match in snippet view article

antineoplastic agent from oxazafosforine group; Mitoxantrone - a synthetic anthracycline analogue (anthraquinone) that is able to intercalate DNA and thus prevent

Halichondrin B (1,463 words) [view diff] exact match in snippet view article find links to article

prior chemotherapy regimens for late-stage disease, including both anthracycline- and taxane-based chemotherapies. Eribulin is marketed by Eisai Co.

Streptomyces glomeratus (327 words) [view diff] exact match in snippet view article find links to article

VN; Maksimova, TS; Ol'khovatova, OL (June 1978). "[Formation of the anthracycline antibiotics, beromycin and nogalamycin, by a new actinomycete species

TopoTarget (2,976 words) [view diff] exact match in snippet view article find links to article

Commission for the treatment of anthracycline extravasation. Savene, developed by TopoTarget is used for the treatment of anthracycline extravasation, a rare complication

Extravasation (intravenous) (988 words) [view diff] exact match in snippet view article

(dexrazoxane for extravasation) is effective in preventing the progression of anthracycline extravasation into progressive tissue necrosis. In two open-label, single

Streptomyces violaceus (247 words) [view diff] exact match in snippet view article find links to article

Mikroorganismen und Zellkulturen [1] Krohn, volume editor, Karsten (2008). Anthracycline chemistry and biology. Berlin: Springer. ISBN 978-3-540-75814-3. {{cite

HTR3C (278 words) [view diff] exact match in snippet view article find links to article

show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy". J. Cancer Res. Clin. Oncol. 134 (10): 1079–86. doi:10

Streptomyces nogalater (695 words) [view diff] exact match in snippet view article find links to article

echinatus DSM40730, and S. peucetius subsp. Caesius ATCC27952 (producers of anthracycline antibiotics)". Cytology and Genetics. 47 (4): 197–201. doi:10.3103/S0095452713040063

Dihydroxyanthraquinone (475 words) [view diff] exact match in snippet view article find links to article

occurs widely in natural products, and is an important feature of the anthracycline antitumour antibiotics. In particular, 1,8-Dihydroxy-9,10-anthraquinone

Breast cancer chemotherapy (876 words) [view diff] exact match in snippet view article find links to article

presence is a highly significant indicator that the tumor will respond to anthracyclines. CEP17 is detected by a common and straightforward test (fluorescent

Streptomyces cinereoruber (301 words) [view diff] exact match in snippet view article find links to article

Karsten Krohn ; with contributions by O. Achmatowicz ... [et (2008). Anthracycline chemistry and biology. Berlin: Springer. ISBN 978-3-540-75815-0. {{cite

HTR3B (1,031 words) [view diff] exact match in snippet view article find links to article

show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy". J. Cancer Res. Clin. Oncol. 134 (10): 1079–1086. doi:10

Wulff–Dötz reaction (1,525 words) [view diff] exact match in snippet view article find links to article

1021/ja00052a090. Wulff, William D.; Tang, Peng Cho (January 1984). "Anthracycline synthesis with Fischer carbene complexes". Journal of the American Chemical

Kurt Hellmann (406 words) [view diff] exact match in snippet view article find links to article

In 1996, he predicted the importance of preventing pharmacological anthracycline cardiotoxicity in quality of life of cancer survivors. A native of Nürnberg

Cardiovascular Cell Therapy Research Network (2,057 words) [view diff] exact match in snippet view article find links to article

Failure in 2021. In September 2016, CCTRN opened enrollment in a study in anthracycline-induced cardiomyopathy (AIC): SENECA (NCT02509156). The purpose of the

Streptomyces violaceochromogenes (170 words) [view diff] exact match in snippet view article find links to article

Mikroorganismen und Zellkulturen [1] ATCC Krohn, Karsten, ed. (2008). Anthracycline chemistry and biology. Berlin: Springer. ISBN 978-3-540-75814-3. Buckingham

Carbonyl reductase (NADPH) (299 words) [view diff] exact match in snippet view article

and 2PFG. Ahmed NK, Felsted RL, Bachur NR (1978). "Heterogeneity of anthracycline antibiotic carbonyl reductases in mammalian livers". Biochem. Pharmacol

Capomycin (94 words) [view diff] exact match in snippet view article find links to article

PMID 3839783. Martins, Cristiane Soares; Souto-Maior, Ana Maria (June 2003). "Anthracycline production by Streptomyces capoamus in batch fermentation". Brazilian

Magnetic-targeted carrier (985 words) [view diff] exact match in snippet view article find links to article

targeted carrier complex, which is composed of a formulation of the anthracycline antibiotic doxorubicin and is bound to microscopic beads of activated

Streptomyces ruber (356 words) [view diff] exact match in snippet view article find links to article

Science + Business Media. ISBN 978-0-387-68233-4. Krohn, Karsten (2008). Anthracycline chemistry and biology. Berlin: Springer. ISBN 978-3-540-75814-3. Kim

CD135 (1,757 words) [view diff] exact match in snippet view article find links to article

FDA-approved test. Precisely, it should be used with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy

Quizartinib (1,236 words) [view diff] exact match in snippet view article find links to article

Quizartinib is indicated, in combination with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy

International Prognostic Index (1,151 words) [view diff] exact match in snippet view article find links to article

developed prior to the use of rituximab, which is now included with anthracycline-based combination chemotherapy as of the standard of care in B-cell

Germinal center B-cell like diffuse large B-cell lymphoma (2,450 words) [view diff] exact match in snippet view article find links to article

"14-3-3ζ Mediates Resistance of Diffuse Large B Cell Lymphoma to an Anthracycline-based Chemotherapeutic Regimen". Journal of Biological Chemistry. 284

Streptomyces purpurascens (497 words) [view diff] exact match in snippet view article find links to article

R; Kopio, A; Mäntsälä, P (June 1994). "Hybrid anthracycline antibiotics: production of new anthracyclines by cloned genes from Streptomyces purpurascens

Forkhead box C1 (1,692 words) [view diff] exact match in snippet view article find links to article

Longhurst TJ, O'Neill GM, Harvie RM, Davey RA (November 1996). "The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug

Iron oxide nanoparticle (3,102 words) [view diff] exact match in snippet view article find links to article

oxide nanoparticles to anticancer drug and tumor cells. In particular, anthracycline antitumor antibiotic doxorubicin, the native state of which is diamagnetic

Free radical damage to DNA (2,109 words) [view diff] exact match in snippet view article find links to article

intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores". Proceedings of the National Academy of Sciences

Basal-like carcinoma (1,745 words) [view diff] exact match in snippet view article find links to article

larger and of later stage, basal-like subtypes are more sensitive to anthracycline-based neoadjuvant chemotherapy than luminal breast cancers. Yet, despite

Topoisomerase (6,211 words) [view diff] exact match in snippet view article find links to article

anthracenedione that is chemically and functionally similar to anthracyclines. The anthracyclines were the first topoisomerase inhibitors used to treat cancer

Shelby Kutty (1,160 words) [view diff] exact match in snippet view article find links to article

(July 1, 2012) Changes in left ventricular longitudinal strain with anthracycline chemotherapy in adolescents precede subsequent decreased left ventricular

Childhood cancer (6,913 words) [view diff] exact match in snippet view article find links to article

heart disease. Survivors of childhood cancer, previously treated with anthracycline chemotherapy (including mitoxantrone) or radiotherapy in which the heart

Neuregulin 1 (4,488 words) [view diff] exact match in snippet view article find links to article

C, Miller TA, Eppenberger HM, Suter TM (April 2002). "Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta

Paul R. Rosenbaum (1,740 words) [view diff] exact match in snippet view article find links to article

"Randomization Inference With Imperfect Compliance in the ACE-Inhibitor After Anthracycline Randomized Trial". Journal of the American Statistical Association.

Tumor hypoxia (5,638 words) [view diff] exact match in snippet view article find links to article

Alshawsh MA, Chik Z (August 2021). "Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer

Johanna Meijer (2,530 words) [view diff] exact match in snippet view article find links to article

Johanna H.; Deboer, Tom (2022). "Induction of Fatigue by Specific Anthracycline Cancer Drugs through Disruption of the Circadian Pacemaker". Cancers

Roberta Gottlieb (2,110 words) [view diff] exact match in snippet view article find links to article

the treatment of reperfusion injury, mitochondria and stem cells in anthracycline-induced heart failure, rescue and role of complex I in myocardial ischemic

Nanoparticle drug delivery (5,277 words) [view diff] exact match in snippet view article find links to article

Various FDA-approved liposomal drugs are in clinical use in the US. The anthracycline drug doxorubicin is delivered with phospholipid-cholesterol liposomes

Joanna Poulton (1,441 words) [view diff] exact match in snippet view article find links to article

(January 2009). "Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs". Biochemical and Biophysical Research Communications. 378 (3):

Fallacinol (2,280 words) [view diff] exact match in snippet view article find links to article

1007/bf03051864. Benfaremo, Nicholas; Cava, Michael P. (1984). "Studies in anthracycline synthesis: simple Diels–Alder routes to pachybasin, ω-hydroxypachybasin