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searching for 5-HT1A receptor 32 found (432 total)

Epix Pharmaceuticals (137 words) [view diff] exact match in snippet view article find links to article

products included the following agents:[citation needed] PRX-00023—5-HT1A receptor full agonist (later discovered to be an antagonist): for major depression

CTN-986 (114 words) [view diff] exact match in snippet view article find links to article

hippocampus. The neurogenesis appears to be mediated by activation of the 5-HT1A receptor, as co-administration with the 5-HT1A antagonist WAY-100,635 abolished

List of investigational antidepressants (11,427 words) [view diff] exact match in snippet view article find links to article

receptor 1 (TAAR1) agonist Ulotaront (SEP-363856; SEP-856) – serotonin 5-HT1A receptor agonist and trace amine-associated receptor 1 (TAAR1) agonist PRAX-114

PB-28 (338 words) [view diff] exact match in snippet view article find links to article

Perrone R, Tortorella V, Govoni S, Lucchi L (1996). "New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives". J. Med. Chem

Alverine (680 words) [view diff] exact match in snippet view article find links to article

antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype". The Journal of Pharmacy and Pharmacology. 53 (10): 1419–1426

C22H25N3O3 (71 words) [view diff] exact match in snippet view article find links to article

Spiroxatrine, a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor This set index page lists chemical

C22H31N3O3 (64 words) [view diff] exact match in snippet view article find links to article

The molecular formula C22H31N3O3 may refer to: BMY-7378, a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist MDMB-CHMINACA

C26H38N2O4 (60 words) [view diff] exact match in snippet view article find links to article

molecular formula C26H38N2O4 may refer to: Alnespirone, a selective 5-HT1A receptor full agonist of the azapirone chemical class Mazipredone, a synthetic

C16H21N3O2 (73 words) [view diff] exact match in snippet view article find links to article

to pindolol which acts as both a β1 adrenoceptor antagonist and a 5-HT1A receptor antagonist This set index page lists chemical structure articles associated

7-OH-DPAT (647 words) [view diff] exact match in snippet view article find links to article

Oerther S, Ahlenius S (July 2001). "Additive hypothermic effects of the 5-HT1A receptor agonist 8-OH-DPAT and the dopamine D2/3 receptor agonist 7-OH-DPAT

Diarylpropionitrile (560 words) [view diff] exact match in snippet view article find links to article

Muma NA, Li Q (August 2010). "Estradiol-induced desensitization of 5-HT1A receptor signaling in the paraventricular nucleus of the hypothalamus is independent

CC2D1A (612 words) [view diff] exact match in snippet view article find links to article

type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene". J. Neurochem. 88 (4): 857–68. doi:10.1046/j.1471-4159.2003.02223

Aporphine (2,135 words) [view diff] exact match in snippet view article find links to article

"11-substituted (R)-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions". Journal of Medicinal Chemistry. 39 (18): 3503–3513.

List of investigational antipsychotics (746 words) [view diff] exact match in snippet view article find links to article

(RG-7906, RO-6889450) – TAAR1 agonist Ulotaront (SEP-856, SEP-363856) – 5-HT1A receptor and TAAR1 agonist Usmarapride (SUVN-D4010) – 5-HT4 receptor partial

Barratt Impulsiveness Scale (1,629 words) [view diff] exact match in snippet view article find links to article

"Ipsapirone challenge in aggressive men shows an inverse correlation between 5-HT1A receptor function and aggression". Psychopharmacology. 148 (4): 344–9. doi:10

List of investigational obsessive–compulsive disorder drugs (944 words) [view diff] exact match in snippet view article find links to article

CR-5542 – orexin receptor antagonist [7] Dual SSRIs and serotonin 5-HT1A receptor agonists (SSA-426, WAY-163426, WAY-211612, WAY-253752, WAY-426) [8]

Glutamate hypothesis of schizophrenia (3,899 words) [view diff] exact match in snippet view article find links to article

S2CID 27008041. Bantick, R. A.; Deakin, J. F.; Grasby, P. M. (2001). "The 5-HT1A receptor in schizophrenia: a promising target for novel atypical neuroleptics

Receptor antagonist (3,921 words) [view diff] exact match in snippet view article find links to article

S2CID 6599658. Fletcher A, Cliffe IA, Dourish CT (December 1993). "Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents". Trends

TPH1 (1,459 words) [view diff] exact match in snippet view article find links to article

(2002). "Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease". J. Neurochem. 82

Biology of obsessive–compulsive disorder (2,993 words) [view diff] exact match in snippet view article find links to article

reported to exacerbate OCD symptoms. Psilocybin, a 5-HT2C, 5-HT2A and 5-HT1A receptor agonist has been associated with acute improvement of OCD symptoms

Dopaminergic pathways (4,256 words) [view diff] exact match in snippet view article find links to article

receptors that exert a biphasic effects on firing, with low doses of 5-HT1A receptor agonists eliciting an increase in firing rate, and higher doses suppressing

Serotonin syndrome (5,327 words) [view diff] exact match in snippet view article find links to article

receptors appears to contribute substantially to the condition. The 5-HT1A receptor may still contribute through a pharmacodynamic interaction in which

Anxiety (10,352 words) [view diff] exact match in snippet view article find links to article

This category of drug works by initiating a physiological response at 5-HT1A receptor by increasing the action of serotonin at this receptor.[citation needed]

List of investigational attention deficit hyperactivity disorder drugs (3,170 words) [view diff] exact match in snippet view article find links to article

receptor modulator Buspirone [transdermal] (BuSpar Patch) – serotonin 5-HT1A receptor partial agonist, other actions Cipralisant (GT-2331; Perceptin) – histamine

Cancer and nausea (4,802 words) [view diff] exact match in snippet view article find links to article

in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation". British Journal of Pharmacology. 168 (6): 1456–1470. doi:10

Apical dendrite (5,967 words) [view diff] exact match in snippet view article find links to article

line-of-sight responses. Chronic administration of corticosteroids decreases 5-HT1A receptor binding, 5-HT2 receptor binding, serotonin levels, and expression of

Benzodiazepine dependence (8,852 words) [view diff] exact match in snippet view article find links to article

12–6. PMID 2891684. Miura S, Murasaki M (March 1992). "The future of 5-HT1A receptor agonists. (Aryl-piperazine derivatives)". Progress in Neuro-Psychopharmacology

Environmental enrichment (6,220 words) [view diff] exact match in snippet view article find links to article

et al. (January 1998). "Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus". Brain Res. Mol

Adult neurogenesis (12,331 words) [view diff] case mismatch in snippet view article find links to article

allows for the production of more brain cells, in particular at the 5-HT1a receptor in the dentate gyrus of the hippocampus which has been shown to improve

Biology of depression (14,956 words) [view diff] exact match in snippet view article find links to article

receptor may be underexpressed in the striatum of people with MDD. 5-HT1A receptor binding literature is inconsistent; however, it leans towards a general

Serotonin–norepinephrine–dopamine reuptake inhibitor (16,227 words) [view diff] exact match in snippet view article find links to article

antagonized. Azapirone-type drugs (e.g., buspirone), which act as 5-HT1A receptor agonists and partial agonists have been developed as anxiolytic agents

Molecular and epigenetic mechanisms of alcoholism (6,687 words) [view diff] no match in snippet view article find links to article

Ladenheim, E.E., Lyons, W.E. (2003). Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (?/-) mice. J Neurochem, 85, 1139–1147