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Agonist-Antagonist is a redirect to agonist-antagonist

searching for Agonist-Antagonist 182 found (230 total)

Oxymorphone-3-methoxynaltrexonazine (68 words) [view diff] case mismatch in snippet view article find links to article

selective μ-opioid receptor agonist, unlike the closely related mixed agonist-antagonist Oxymorphonenaltrexonazine. Naloxonazine Naloxone Naltrexone Oxymorphone

Lubabegron (394 words) [view diff] no match in snippet view article find links to article

approved for use in Canada. Lubabegron is a beta-adrenergic receptor agonist/antagonist. The antagonist activity of lubabegron at β1 and β2 receptors prevents

Interposed nucleus (382 words) [view diff] no match in snippet view article find links to article

interposed nucleus. The interposed nucleus is responsible for coordinating agonist/antagonist muscle pairs, and therefore a lesion in this area causes tremor. The

Dichloroisoprenaline (131 words) [view diff] no match in snippet view article find links to article

β2-adrenergic receptors. DCI has low potency and acts as a partial agonist/antagonist at these receptors. Although DCI was of no clinical value itself,

UH-232 (501 words) [view diff] case mismatch in snippet view article find links to article

UH-232 ((+)-UH232) is a drug which acts as a subtype selective mixed agonist-antagonist for dopamine receptors, acting as a weak partial agonist at the D3

O-823 (192 words) [view diff] no match in snippet view article find links to article

derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor CB1, meaning that it acts as an antagonist

18-Deoxyaldosterone (75 words) [view diff] case mismatch in snippet view article find links to article

18-Deoxyaldosterone is a steroidal antimineralocorticoid with mixed agonist–antagonist but predominantly antagonistic activity at the mineralocorticoid receptor

Selective estrogen receptor modulator (6,581 words) [view diff] no match in snippet view article find links to article

breast cancer. Class identifiers Synonyms SERM; Estrogen receptor agonist/antagonist; ERAA Use Breast cancer, infertility, osteoporosis, vaginal atrophy

Moxazocine (304 words) [view diff] no match in snippet view article find links to article

family which was never marketed. It acts as a partial agonist or mixed agonist/antagonist of the opioid receptors and binds preferentially to the κ-opioid receptor

Picenadol (381 words) [view diff] case mismatch in snippet view article find links to article

This means that the racemic mix of the two enantiomers is a mixed agonist-antagonist, with relatively low abuse potential, and little of the κ-opioid activity

Spinorphin (356 words) [view diff] no match in snippet view article find links to article

act as an antagonist of the P2X3 receptor, and as a weak partial agonist/antagonist of the FP1 receptor. Enkephalinase inhibitor Liang TS, Gao JL, Fatemi

Nalmexone (240 words) [view diff] case mismatch in snippet view article find links to article

EN-1620A and UM-592) is a semisynthetic, opioid partial agonist or mixed agonist-antagonist with both analgesic and narcotic antagonist properties that was never

Meptazinol (172 words) [view diff] no match in snippet view article find links to article

4-phenylazepanes. A partial μ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full

Ciproxifan (481 words) [view diff] no match in snippet view article find links to article

Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist. The histamine H3 receptor is an inhibitory autoreceptor located on histaminergic

O-806 (142 words) [view diff] no match in snippet view article find links to article

derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor CB1, meaning that it acts as an antagonist

Nalorphine dinicotinate (153 words) [view diff] case mismatch in snippet view article find links to article

dinicotinoylnalorphine, or niconalorphine, is a semisynthetic, mixed opioid agonist-antagonist which is described as a narcotic antagonist but may produce limited

BMY-7378 (66 words) [view diff] no match in snippet view article find links to article

BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist. Goetz AS, King HK, Ward SD, True TA, Rimele TJ,

Cyclofenil (1,158 words) [view diff] case mismatch in snippet view article find links to article

selective estrogen receptor modulator (SERM) and hence is a mixed agonist–antagonist of the estrogen receptor (ER), the biological target of estrogens

TM-38837 (166 words) [view diff] no match in snippet view article find links to article

TM-38837 is a small molecule inverse agonist/antagonist of the CB1 cannabinoid receptor, with peripheral selectivity. It is being developed for the treatment

Journal of Enzyme Inhibition and Medicinal Chemistry (99 words) [view diff] no match in snippet view article find links to article

research on enzyme inhibitors and inhibitory processes as well as agonist/antagonist receptor interactions in the development of medicinal and anti-cancer

Conorfone (257 words) [view diff] case mismatch in snippet view article find links to article

8-ethyl group and an N-cyclopropylmethyl group. It acts as a mixed agonist-antagonist at the μ-opioid receptor, and is slightly more potent than codeine

Cyclazocine (256 words) [view diff] no match in snippet view article find links to article

Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. This family of opioid drugs is called the benzomorphans

Profadol (221 words) [view diff] case mismatch in snippet view article find links to article

which was developed in the 1960s by Parke-Davis. It acts as a mixed agonist-antagonist of the μ-opioid receptor. The analgetic potency is about the same

Receptor modulator (982 words) [view diff] no match in snippet view article find links to article

addition, depending on the cell type, the specific effect, whether agonist, antagonist, inverse agonist, etc., could have a unique specific effect. An example

Ciramadol (474 words) [view diff] case mismatch in snippet view article find links to article

phencyclidine, tramadol, tapentadol and venlafaxine. It is a mixed agonist-antagonist for the μ-opioid receptor with relatively low abuse potential and

Enzyme modulator (106 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Reuptake modulator (52 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Enzyme inducer (170 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Neuroprosthetics (5,490 words) [view diff] case mismatch in snippet view article find links to article

neurally with high reliability. This surgical paradigm, termed the agonist-antagonist myoneural interface (AMI), provides the user with the ability to sense

Release modulator (175 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Jed Rose (scientist) (2,624 words) [view diff] case mismatch in snippet view article

commercial nicotine skin patches. Rose is also responsible for studying agonist-antagonist treatments that provided support for the development varenicline (Chantix)

Dezocine (2,499 words) [view diff] no match in snippet view article find links to article

gastrointestinal discomfort and dizziness. Because decozine has mixed agonist/antagonist effects at the opioid receptors, it has a lowered dependence potential

Raloxifene (4,794 words) [view diff] case mismatch in snippet view article find links to article

selective estrogen receptor modulator (SERM) and therefore a mixed agonist–antagonist of the estrogen receptor (ER). It has estrogenic effects in bone and

Histaminergic (97 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

GABAergic (139 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Histamine agonist (140 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Sodium channel opener (112 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Drug class (1,006 words) [view diff] no match in snippet view article find links to article

that biological target. For receptors, these activities include agonist, antagonist, inverse agonist, or modulator. Enzyme target mechanisms include

Receptor theory (2,007 words) [view diff] no match in snippet view article find links to article

fractional or proportional change. This is demonstrated by the effects of agonist/ antagonist combinations on the desensitization of receptors. This is also demonstrated

Glutamatergic (63 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Galangin (464 words) [view diff] no match in snippet view article find links to article

"The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor". British Journal of Cancer. 79 (9/10):

Alpinia officinarum (599 words) [view diff] no match in snippet view article find links to article

"The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor". British Journal of Cancer. 79 (9/10):

Aging movement control (2,976 words) [view diff] case mismatch in snippet view article find links to article

normalized force of the elbow flexors may be due to an increase in agonist-antagonist muscles coactivation. Compared to the young group, the old group has

Channel modulator (296 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Glycinergic (47 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Chloride channel blocker (486 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Melatonergic (44 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Oxymorphazone (422 words) [view diff] case mismatch in snippet view article find links to article

as lofentanil. Chlornaltrexamine, an irreversible mixed μ-opioid agonist-antagonist Chloroxymorphamine, another irreversible μ-opioid full agonist Naloxazone

Parasympatholytic (258 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Vasopressin receptor antagonist (1,059 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Channel opener (82 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

CGS-20625 (319 words) [view diff] no match in snippet view article find links to article

Bennett DA (1987). "Pharmacology of the pyrazolo-type compounds: agonist, antagonist and inverse agonist actions". Physiol. Behav. 41 (3): 241–5. doi:10

C22H31N3O3 (64 words) [view diff] no match in snippet view article find links to article

C22H31N3O3 may refer to: BMY-7378, a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist MDMB-CHMINACA, an indazole-based

Naloxazone (238 words) [view diff] case mismatch in snippet view article find links to article

opioid receptor binding. Chlornaltrexamine, an irreversible mixed agonist-antagonist Oxymorphazone, an irreversible μ-opioid full agonist Pasternak, G

Sympatholytic (1,304 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Adrenergic (286 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Excitatory amino acid receptor agonist (73 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Calcium channel opener (283 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Propiram (629 words) [view diff] no match in snippet view article find links to article

system are not well understood. Other drugs of the partial μ-opioid agonist/antagonist type include meptazinol, buprenorphine, butorphanol, phenazocine,

Enzyme repressor (48 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

40S ribosomal protein S19 (1,240 words) [view diff] no match in snippet view article find links to article

Tanaka Y, Nishino N, Shibuya Y, Yamamoto T (2003). "Switch Moiety in Agonist/Antagonist Dual Effect of S19 Ribosomal Protein Dimer on Leukocyte Chemotactic

Alpha-2 blocker (339 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Excitatory amino acid receptor antagonist (81 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Adrenergic agonist (757 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Jarisch–Herxheimer reaction (838 words) [view diff] no match in snippet view article find links to article

pressure. If available, meptazinol, an opioid analgesic of the mixed agonist/antagonist type, should be administered to reduce the severity of the reaction

Reverse transport (744 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Center-surround antagonism (70 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Potassium channel opener (831 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

GW0742 (827 words) [view diff] no match in snippet view article find links to article

investigated for drug use by GlaxoSmithKline. It is mixed PPAR-B agonist antagonist depending on its dosage. It has weak activity on multiple nuclear

Opioidergic (409 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Reuptake enhancer (403 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

7-Hydroxymitragynine (594 words) [view diff] no match in snippet view article find links to article

7-Hydroxymitragynine, like mitragynine, appears to be a mixed opioid receptor agonist/antagonist, with recent research indicating that it acts as a partial agonist

GABA receptor agonist (749 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Beta1-adrenergic agonist (322 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Ballistic movement (1,961 words) [view diff] no match in snippet view article find links to article

concurrent agonist and antagonist muscles or the characteristic triphasic agonist/antagonist/agonist muscle activation. Electromyography (EMG) recordings of demonstrate

Cholinesterase inhibitor (1,130 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Amputation (5,436 words) [view diff] case mismatch in snippet view article find links to article

with similar goals, which has been tested in a clinical trial, is Agonist-antagonist Myoneural Interface (AMI). In 1920, Dr. Janos Ertl Sr. of Hungary

Dopamine agonist (5,006 words) [view diff] case mismatch in snippet view article find links to article

studies suggest that ergot alkaloids have the properties of mixed agonist-antagonist with regards to certain presynaptic and postsynaptic receptors. N-n-Propyl

Adenosinergic (55 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Nicotinic antagonist (172 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Excitatory amino acid reuptake inhibitor (479 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Analgesic (5,853 words) [view diff] no match in snippet view article find links to article

hydrochloride salt. Full agonist at kappa opioid receptors, partial agonist/antagonist at the mu opioid receptors. IM, IV, SC. Protein binding = not significant;

Poor ovarian reserve (3,740 words) [view diff] no match in snippet view article find links to article

beginning of the stimulation protocol. Gonadotropin-releasing hormone agonist/antagonist conversion with estrogen priming (AACEP) protocol. Fisch, Keskintepe

4-Androstenediol (272 words) [view diff] no match in snippet view article find links to article

humans". Chen F, Knecht K, Leu C, et al. (August 2004). "Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol".

Hormonal contraception (5,332 words) [view diff] case mismatch in snippet view article find links to article

including ulipristal acetate (UPA), an oral progesterone receptor agonist-antagonist; levonorgestrel (LNG), an oral progestin; off-label use of combined

Strength training (9,500 words) [view diff] case mismatch in snippet view article find links to article

superset configurations are two exercises for the same muscle group, agonist-antagonist muscles, or alternating upper and lower body muscle groups. Exercises

Parasympathomimetic drug (618 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Neurotransmitter transporter (988 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Muscarinic agonist (858 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Adrenergic antagonist (1,535 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Endocannabinoid enhancer (357 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Glycine receptor antagonist (125 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Benzhydrocodone (1,175 words) [view diff] no match in snippet view article find links to article

Benzhydrocodone/APAP use with serotonergic drugs can cause serotonin syndrome. Mixed agonist/antagonist and partial agonist opioids may reduce the analgesic effect of benzhydrocodone/APAP

Glycine receptor agonist (41 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Opioid (19,900 words) [view diff] no match in snippet view article find links to article

Dezocine—agonist/antagonist Pentazocine—agonist/antagonist Phenazocine Buprenorphine—partial agonist Dihydroetorphine Etorphine Butorphanol—agonist/antagonist

Serotonin receptor antagonist (503 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Adenosine reuptake inhibitor (1,583 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Ganglionic blocker (446 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Allosteric modulator (2,293 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

RTI-51 (544 words) [view diff] no match in snippet view article find links to article

Bandyopadhyay BC, Araldi GL, Carmona G, et al. (April 2003). "Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidin

H4-CBD (303 words) [view diff] no match in snippet view article find links to article

contrast, CBD has been found to bind to the CB1 receptor as an inverse agonist/antagonist with a Ki ranging from 3.3 to 4.8 mM. In 2023 H4CBD epimers were elucidated

TRPV3 (1,448 words) [view diff] case mismatch in snippet view article find links to article

pain perception. 2-Aminoethoxydiphenyl borate (2-APB) is a mixed agonist-antagonist of the TRPV3 receptor, acting as an antagonist at low concentrations

Cholinergic (972 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Dopamine antagonist (2,530 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

RTI-31 (637 words) [view diff] no match in snippet view article find links to article

Bandyopadhyay BC, Araldi GL, Carmona G, et al. (April 2003). "Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidin

Anatomical terms of muscle (2,285 words) [view diff] no match in snippet view article find links to article

uncontrolled and disturbs the control of the joint action. This is called agonist/antagonist co-activation and serves to mechanically stiffen the joint. Not all

Everhardus Jacobus Ariëns (699 words) [view diff] no match in snippet view article find links to article

describe the behavior of agonists and antagonists as well as the dual agonist / antagonist behavior of partial agonists. An important accomplishment of Ariëns

Ospemifene (1,615 words) [view diff] no match in snippet view article find links to article

estrogen/progestin therapy.[citation needed] Ospemifene is "an estrogen agonist/antagonist that makes vaginal tissue thicker and less fragile resulting in a

Reuptake inhibitor (1,917 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Anticholinergic (2,614 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Dinalbuphine sebacate (832 words) [view diff] no match in snippet view article find links to article

packaged in a carton. Nalbuphine, and hence DNS, acts as a mixed agonist/antagonist opioid modulator, or more specifically as a moderate-efficacy partial

Selective androgen receptor modulator (6,716 words) [view diff] no match in snippet view article find links to article

between the N-terminus and C-terminus of AR which resulted in a mixed agonist/antagonist mode of action. In addition to the regulation of gene expression by

CCK-4 (897 words) [view diff] no match in snippet view article find links to article

M, Herranz R (2007). "Strategies for design of non peptide CCK1R agonist/antagonist ligands". Current Topics in Medicinal Chemistry. 7 (12): 1180–94.

Alpha-adrenergic agonist (1,308 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

SPEN (855 words) [view diff] case mismatch in snippet view article find links to article

PMID 14702039. Dotzlaw H, Papaioannou M, Moehren U, et al. (2004). "Agonist-antagonist induced coactivator and corepressor interplay on the human androgen

Beta2-adrenergic agonist (1,703 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Beta2-adrenergic agonist (1,703 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Drug (3,411 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

FGF5 (2,251 words) [view diff] no match in snippet view article find links to article

factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity". The Journal of Biological Chemistry

H1 antagonist (1,910 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

H3 receptor antagonist (2,202 words) [view diff] no match in snippet view article find links to article

propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology". Journal

Bionovo (987 words) [view diff] no match in snippet view article find links to article

SERMs, such as tamoxifen and raloxifene, since these drugs have mixed agonist/antagonist activity and are not selective in transcriptional regulation to one

Beta-adrenergic agonist (851 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

H2 receptor antagonist (2,249 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Serotonin receptor agonist (1,664 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Osemozotan (1,548 words) [view diff] no match in snippet view article find links to article

cocaine-induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice". Synapse. 60 (7): 479–84. doi:10.1002/syn.20323. PMID 16952156

Yuehchukene (737 words) [view diff] no match in snippet view article find links to article

or synthetic estrogen compounds (e.g bisphenol A). It is a mixed agonist/antagonist, binding competitively to rat uterine estrogen receptors, though with

Ligand (biochemistry) (3,166 words) [view diff] no match in snippet view article

quantitative magnitude of this response. This response may be as an agonist, antagonist, or inverse agonist, depending on the physiological response produced

RTI-113 (1,157 words) [view diff] no match in snippet view article find links to article

Bandyopadhyay BC, Araldi GL, Carmona G, et al. (April 2003). "Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidin

Antihistamine (3,300 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Metabotropic glutamate receptor 3 (3,103 words) [view diff] no match in snippet view article find links to article

used in previous trials of schizophrenia and anxiety disorder. The agonist, antagonist and allosteric modulator drugs of mGluR3 can now be explored as new

Walter Leal (2,002 words) [view diff] case mismatch in snippet view article find links to article

"Chemical communication in scarab beetles: reciprocal behavioral agonist-antagonist activities of chiral pheromones". Proceedings of the National Academy

Interstitial lung disease (2,996 words) [view diff] case mismatch in snippet view article find links to article

breathlessness symptoms in those with end stage lung disease. The opiate agonist-antagonist nalbuphine and morphine are also known to improve coughing in those

Adenosine receptor agonist (283 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Ligand-gated ion channel (2,599 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Channel blocker (3,020 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Umespirone (504 words) [view diff] case mismatch in snippet view article find links to article

PMID 1671523. Ahlenius S, Wijkström A (November 1992). "Mixed agonist-antagonist properties of umespirone at neostriatal dopamine receptors in relation

Neuromodulation (3,671 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Aripiprazole (9,668 words) [view diff] no match in snippet view article find links to article

is unlikely that the differential actions of aripiprazole as an agonist, antagonist, or partial agonist were entirely due to differences in relative

NK1 receptor antagonist (3,286 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Franca Ronchese (854 words) [view diff] no match in snippet view article find links to article

"Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell

ZK-93423 (614 words) [view diff] no match in snippet view article find links to article

relationship study of some benzodiazepine-receptor ligands having inverse agonist/antagonist and agonist actions". Drug Design and Discovery. 9 (2): 135–43. PMID 1338366

Alpha blocker (3,197 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Muscle imbalance (1,726 words) [view diff] case mismatch in snippet view article find links to article

unclear, tests confirmed that the cause was an imbalance with the agonist-antagonist functional relationship. Treatment now includes anti-inflammatory

Dopaminergic (2,798 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Monoaminergic (94 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Azapirone (2,701 words) [view diff] case mismatch in snippet view article find links to article

PMID 1685786. S2CID 9762359. Ahlenius S, Wijkström A (November 1992). "Mixed agonist-antagonist properties of umespirone at neostriatal dopamine receptors in relation

Alpha-1 blocker (4,296 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Buprenorphine/naloxone (3,519 words) [view diff] no match in snippet view article find links to article

profile than methadone and limited respiratory effects, due to both agonist/antagonist effects. But buprenorphine/naloxone may be less safe than methadone

Francisco Torrent-Guasp (1,398 words) [view diff] case mismatch in snippet view article find links to article

Rev Esp Cardiol. 1998 Jul;51(7):521-8. Torrent Guasp, Francisco. Agonist-antagonist mechanics of the descendente and ascendente segmentos of the ventricular

Enobosarm (12,937 words) [view diff] case mismatch in snippet view article find links to article

potentially also others like enobosarm, than men. In addition to its mixed agonist–antagonist activity at the AR, enobosarm is likely to also differ from steroidal

Μ-opioid receptor (4,884 words) [view diff] case mismatch in snippet view article find links to article

PMC 5561344. PMID 28303899. Hoskin PJ, Hanks GW (March 1991). "Opioid agonist-antagonist drugs in acute and chronic pain states". Drugs. 41 (3): 326–344. doi:10

Neural adaptation (3,694 words) [view diff] case mismatch in snippet view article find links to article

for increases in strength relating to neural adaptation include: agonist-antagonist muscle decreased co-activation, motor unit synchronization, and motor

NMDA receptor antagonist (4,196 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Cyproheptadine (2,232 words) [view diff] no match in snippet view article find links to article

DATTooltip Dopamine transporter 4100 Human The smaller the equilibrium constant, the more strongly the drug binds to the site. ↑ Agonist ↓ Antagonist

Ergoline (3,836 words) [view diff] no match in snippet view article find links to article

agonist behavior of the ergolines are substrate dependent and mixed agonist/antagonist behaviors of ergoline derivatives have been reported. The primary

Brilaroxazine (1,729 words) [view diff] no match in snippet view article find links to article

agonist D5 200 ND 5-HT1A 1.5 Partial agonist 5-HT2A 2.5 Weak partial agonist/ Antagonist 5-HT2B 0.19 Antagonist 5-HT2C 39 Antagonist 5-HT3 78 ND 5-HT6 51

Proprioception (7,067 words) [view diff] case mismatch in snippet view article find links to article

thought to regulate reciprocal inhibition in muscles, leading to agonist-antagonist muscle pairs. When planning complex movements such as reaching or

Polio (12,899 words) [view diff] no match in snippet view article find links to article

the difference in leg lengths. Other surgery to re-balance muscular agonist/antagonist imbalances may also be helpful. Extended use of braces or wheelchairs

Chloride channel opener (4,517 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Cannabinoid receptor antagonist (4,204 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Angiotensin II receptor blocker (5,341 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Muscarinic antagonist (2,060 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Dehydroepiandrosterone (4,197 words) [view diff] no match in snippet view article find links to article

Schmidt A, Harada S, Freedman LP, Reszka AA (November 2005). "Direct agonist/antagonist functions of dehydroepiandrosterone". Endocrinology. 146 (11): 4568–76

Cannabinoid (7,814 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Motion sickness (5,053 words) [view diff] case mismatch in snippet view article find links to article

operation of Sherrington's Law describing reciprocal inhibition between agonist-antagonist muscle pairs, and by implication the stretching of extraocular muscle

Nuclear receptor (6,513 words) [view diff] no match in snippet view article find links to article

while minimizing undesirable side effects. Drugs with this mixed agonist/antagonist profile of action are referred to as selective receptor modulators

5-HT3 antagonist (4,628 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Neuromuscular-blocking drug (6,872 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Proprioception and motor control (1,729 words) [view diff] case mismatch in snippet view article find links to article

Samantha; Song, Hyungeun; Barry, Robert L.; Herr, Hugh M. (2020-12-09). "Agonist-antagonist myoneural interface amputation preserves proprioceptive sensorimotor

Stimulant (13,257 words) [view diff] no match in snippet view article find links to article

dependence, however, caution is advised. Pitolisant is an inverse agonist (antagonist) of the histamine 3 (H3) autoreceptor. As such, pitolisant is an

FAUC50 (148 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Nicotinic agonist (4,207 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Toll-like receptor 4 (9,110 words) [view diff] no match in snippet view article find links to article

Pentoxifylline (and downregulate TLR4 expression) Tapentadol (mixed agonist/antagonist) TLR4-IN-C34 Palmitoylethanolamide GRCh38: Ensembl release 89: ENSG00000136869

Anabolic steroid (21,556 words) [view diff] no match in snippet view article find links to article

and aromatization in target tissues and the tissue-specific partial agonist/antagonist properties of some synthetic androgens may lead to more physiological

Degrees of freedom problem (3,545 words) [view diff] case mismatch in snippet view article find links to article

similarly complex. While each joint is commonly understood as having an agonist-antagonist pair, not all joint movement is controlled locally. Finally, movement

5-HT2C receptor agonist (5,032 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

List of cocaine analogues (5,561 words) [view diff] no match in snippet view article find links to article

Inhibitor ♦ Ion channel: Opener Blocker ♦ Receptor: Agonist Partial agonist Antagonist Inverse agonist Positive allosteric modulator (PAM) Negative allosteric

Head-twitch response (9,101 words) [view diff] case mismatch in snippet view article find links to article

head twitching in rats by lisuride: a mixed 5-hydroxytryptamine agonist-antagonist?". Neurosci Lett. 60 (2): 207–213. doi:10.1016/0304-3940(85)90245-9

Isamide (192 words) [view diff] case mismatch in snippet view article find links to article

tb13525.x. PMID 39134. Huidobro-Toro JP, Foree B (February 1980). "Dual agonist-antagonist effects of 5-hydroxytryptamine (5-HT) in the guinea pig ileum: evidence

Health effects of Bisphenol A (20,820 words) [view diff] no match in snippet view article find links to article

affecting estrogen. A study in mice shows that BPA as an EDC acts as an agonist/antagonist for behavioral effects. BPA caused a decrease in exploratory and spatial

Pharmacology of bicalutamide (20,584 words) [view diff] no match in snippet view article find links to article

selective androgen receptor modulator (SARM), or a tissue-selective mixed agonist/antagonist or partial agonist of the AR, with antiandrogenic effects in some