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Longer titles found: Viral vector vaccine (view), Retinal gene therapy using lentiviral vectors (view), Lentiviral vector in gene therapy (view)

searching for Viral vector 86 found (269 total)

alternate case: viral vector

Zika virus vaccine (1,263 words) [view diff] no match in snippet view article find links to article

A Zika virus vaccine is designed to prevent the symptoms and complications of Zika virus infection in humans. As Zika virus infection of pregnant women
Jesse Gelsinger (626 words) [view diff] exact match in snippet view article find links to article
having suffered a massive immune response triggered by the use of the viral vector to transport the gene into his cells, leading to multiple organ failure
Thermo Fisher Scientific (3,849 words) [view diff] case mismatch in snippet view article find links to article
Acquires Viral Vector Manufacturing Business from Novasep". BioSpace. "Thermo Fisher Takes Deep Dive into Cell and Gene Therapy with Viral Vector Business
Gene-activated matrix (183 words) [view diff] exact match in snippet view article find links to article
reproducible tissue regeneration. The matrix can be modified by incorporating a viral vector, mRNA or DNA bound to a delivery system, or a naked plasmid. Bonadio
Vaccine shedding (1,408 words) [view diff] exact match in snippet view article find links to article
vaccine technologies such as inactivated vaccine (killed-virus vaccines), viral vector vaccine, RNA vaccines (that contain no virus), or subunit vaccines (a
Mydicar (814 words) [view diff] exact match in snippet view article find links to article
The SERCA2a gene is delivered to the heart via an adeno-associated viral vector. Using the α-myosin heavy chain gene promoter in the cardiac muscle cells
Oncogene (3,182 words) [view diff] exact match in snippet view article find links to article
initially found to induce cancer in animals when they are introduced through viral vector infection, which carries genetic information from a prior host cell.
Ixoberogene soroparvovec (159 words) [view diff] exact match in snippet view article find links to article
Biotechnologies for wet age-related macular degeneration. It is delivered via the viral vector AAV.7m8. Gelfman, Claire M.; Grishanin, Ruslan; Bender, Kristina Oresic;
Christine Rollier (714 words) [view diff] exact match in snippet view article find links to article
professor at the University of Surrey. She focusses on the development of viral vector vaccines to treat infectious diseases. In particular, Rollier has focussed
Animal models of Parkinson's disease (3,147 words) [view diff] exact match in snippet view article find links to article
fibrils to the SNpc, thus, lacking abundant neurodegeneration. Through the viral vector-mediated delivery of alpha-synuclein, the vectors can target the dopaminergic
Transposase (2,547 words) [view diff] exact match in snippet view article find links to article
Hackett, P.B. (2011). The Sleeping Beauty transposon system – A non-viral vector for gene therapy. Hum. Mol. Genet. (in press)Aronovich EL, McIvor RS
Marylyn Addo (1,268 words) [view diff] exact match in snippet view article find links to article
disease and the MERS coronavirus EMC/2012. She is currently developing a viral vector based COVID-19 vaccine. Addo is the daughter of a Ghanaian father and
Etranacogene dezaparvovec (784 words) [view diff] exact match in snippet view article find links to article
adeno-associated virus vector-based gene therapy which consists of a viral vector carrying a gene for clotting Factor IX. The gene is expressed in the
Novasep (347 words) [view diff] exact match in snippet view article find links to article
headquarters was moved from Pompey in Lorraine to Lyon. Novasep's Belgium viral vector manufacturing division, Henogen, was sold to Thermo Fisher for €725 million
Transflammation (690 words) [view diff] exact match in snippet view article find links to article
These conclusions suggest that transcription factor transfer by the viral vector enhances reprogramming efficiency and processes that are involved in
Short hairpin RNA (1,259 words) [view diff] exact match in snippet view article find links to article
developed acute T-cell leukaemia. This was determined to have been caused by viral vector insertion location. Potential oversaturation of RISC is also a problem
Adrian V. S. Hill (1,080 words) [view diff] exact match in snippet view article find links to article
partial efficacy using Adenovirus and Modified vaccinia Ankara (MVA) viral vector vaccines in a prime-boost regime. From 2005 he has played a leading role
Jean Bennett (2,340 words) [view diff] exact match in snippet view article find links to article
testing visual function using virtual mobility tests, (2019). Trans-viral vector mediated gene transfer to the retina, (abandoned). Modified AAV8 capsid
Transposon mutagenesis (2,213 words) [view diff] exact match in snippet view article find links to article
Sleeping Beauty transposon system (SBTS) is the first successful non-viral vector for incorporation of a gene cassette into a vertebrate genome. Up until
Gene therapy for color blindness (2,323 words) [view diff] exact match in snippet view article find links to article
Gene expression could stabilize if a sufficiently high dose of the viral vector is given. In 2009, adult dichromatic squirrel monkeys were converted
Gene therapy of the human retina (4,699 words) [view diff] exact match in snippet view article find links to article
Bennett J (December 2001). "Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as
Human foamy virus (1,310 words) [view diff] exact match in snippet view article find links to article
(endoplasmic reticulum membrane); it results in low extracellular titers of the viral vector. Meiering, Christopher D.; Maxine L. Linial (January 2001). "Historical
Hydrodynamic delivery (1,000 words) [view diff] exact match in snippet view article find links to article
Alternative methods can be used to insert genes into an organism without a viral vector. These can be split into physical and chemical techniques. Physical methods:
Vole (2,794 words) [view diff] exact match in snippet view article find links to article
behavior to resemble that of prairie voles in experiments in which a viral vector was used to increase a single gene's expression within a particular brain
Katherine A. High (1,439 words) [view diff] exact match in snippet view article find links to article
sponsored, and conducted the first clinical trial of an adeno-associated viral vector (AAV) gene therapy injected into the skeletal muscle (1999), the first
Alipogene tiparvovec (1,171 words) [view diff] exact match in snippet view article find links to article
three patients for €1 each. The adeno-associated virus serotype 1 (AAV1) viral vector delivers an intact copy of the human lipoprotein lipase (LPL) gene to
Academy of Military Medical Sciences (1,000 words) [view diff] exact match in snippet view article find links to article
66% efficacy in a global trial. Convidecia is also similar to other viral vector vaccines like the Oxford–AstraZeneca vaccine and Sputnik V vaccine. Its
Mirus Bio (582 words) [view diff] exact match in snippet view article find links to article
mouse liver; new chemistries for transfection; development of a non-viral vector providing sustained liver-specific transgene expression for more than
Michael W. Bevan (821 words) [view diff] exact match in snippet view article find links to article
"Expression of a flower-specific Myb protein in leaf cells using a viral vector causes ectopic activation of a target promoter". Proceedings of the National
Neurturin (1,468 words) [view diff] exact match in snippet view article find links to article
Ceregene sponsored a double-blind phase II clinical trial of CERE-120, a viral vector mediated gene transfer drug that allows for the continuous delivery of
Genetically modified sperm (635 words) [view diff] exact match in snippet view article find links to article
inserted into living cells in order to change how proteins are created. A viral vector is often used to deliver the gene of interest to the chromosomes in the
Allotopic expression (725 words) [view diff] exact match in snippet view article find links to article
areas. The company suspected the outcome was due to the transferal of viral vector DNA from the treated eye to the untreated eye of each patient, and thus
ATC code J07 (708 words) [view diff] exact match in snippet view article find links to article
33, 45, 52, 58) J07BN01 Covid-19, RNA-based vaccine J07BN02 Covid-19, viral vector, non-replicating J07BN03 Covid-19, inactivated virus J07BN04 Covid-19
Orthobunyavirus (1,679 words) [view diff] exact match in snippet view article find links to article
paraensis). Although transmission by ticks and bed bugs may also occur. Viral vector preference is generally strict, with only a one or very small number
Conditional gene knockout (1,292 words) [view diff] exact match in snippet view article find links to article
recombination and gene trapping. Both methods usually have a modified viral vector or a linear fragment as the mode of transportation of the artificial
Sudhanshu Vrati (1,386 words) [view diff] exact match in snippet view article find links to article
December 2017. "Dna encoding ovine adenovirus (oav287) and its use as a viral vector". Google Patents. 12 December 2017. Retrieved 12 December 2017. "Biological
MVA-B (1,047 words) [view diff] exact match in snippet view article find links to article
titled Gag, Pol, Nef and Env. An improved version of the recombinant viral vector, which was titled MVA-B ΔA40R, was created and published in February
Cloning vector (2,517 words) [view diff] exact match in snippet view article find links to article
insertional mutagenesis caused by integration into host chromosomes by viral vector. Viruses that infect plant and animal cells have also been manipulated
Obsidian Kingdom (2,344 words) [view diff] case mismatch in snippet view article find links to article
2005–present Members Rider G Omega Ojete Mordaza II Om Rex Orale Jade Riot Cul Viral Vector Lips Past members Eaten Roll I Seerborn Ape Tot Zer0 Æmeour Íggdrasil
Viviana Gradinaru (1,056 words) [view diff] exact match in snippet view article find links to article
These technologies include optogenetics and CLARITY. She developed viral vector screening methods to create gene delivery vehicles that can cross the
LEAPER gene editing (783 words) [view diff] exact match in snippet view article find links to article
achieved when LEAPER editing using arRNA151 is delivered via a plasmid or viral vector or as a synthetic oligonucleotide, though this efficiency varied significantly
Stanley Center for Psychiatric Research at Broad Institute (984 words) [view diff] case mismatch in snippet view article find links to article
Neurobiology Jen Pan Director, Translational Research Jeff Cottrell Director, Medicinal Chemistry Florence Wagner Director, Viral Vector Engineering Ben Deverman
Video game piracy (2,143 words) [view diff] case mismatch in snippet view article find links to article
Moshirnia, Andrew (2018-01-01). "Typhoid Mario: Video Game Piracy as Viral Vector and National Security Threat". 93 Indiana Law Journal 975 (2018). 93
Molecular biology (5,069 words) [view diff] exact match in snippet view article find links to article
naked DNA, conjugation via cell-cell contact or by transduction via viral vector. Introducing DNA into eukaryotic cells, such as animal cells, by physical
BioMarin Pharmaceutical (1,669 words) [view diff] exact match in snippet view article find links to article
Valoctocogene roxaparvovec (branded as Roctavian) is an adeno-associated viral vector for treatment of hemophilia A that aims to transfer a working copy of
Sepik virus (2,022 words) [view diff] exact match in snippet view article find links to article
arboviruses, is transmitted from a host reservoir to humans through a viral vector. Some arboviruses can be maintained in a population with minimal input
Spark Therapeutics (904 words) [view diff] exact match in snippet view article find links to article
partnership with Pfizer. Fidanacogene elaparvovec is an adeno-associated viral vector which is designed to transfer a working copy of the Factor IX gene into
SEPT5 (1,358 words) [view diff] exact match in snippet view article find links to article
(October 2003). "Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1". Proceedings
R. Jude Samulski (948 words) [view diff] exact match in snippet view article find links to article
current FDA-approved AAV gene therapies. His work demonstrated AAV2 as a viral vector for gene therapy which led to the first U.S. Patent for inserting genes
Sanfilippo syndrome (3,055 words) [view diff] case mismatch in snippet view article find links to article
Marc (February 2014). "Intracerebral Administration of Adeno-Associated Viral Vector Serotype rh.10 Carrying Human SGSH and SUMF1 cDNAs in Children with
Vision rehabilitation (1,966 words) [view diff] exact match in snippet view article find links to article
treat visual impairments. In this approach, DNA is modified through a viral vector, and then cells related to vision cease translating faulty proteins.
Tobacco rattle virus (1,796 words) [view diff] exact match in snippet view article find links to article
such as alfalfa, to compete against weeds that may otherwise harbor the viral vector. In contrast, nightshade is a very problematic weed as it is an ideal
Programmed cell death protein 1 (4,993 words) [view diff] exact match in snippet view article find links to article
a role in negatively regulating CD8+ T cell responses, using an LCMV viral vector model of chronic infection, Rafi Ahmed's group showed that the PD-1-PD-L1
Myzus persicae (2,984 words) [view diff] exact match in snippet view article find links to article
different plant viruses, thus being the world's most versatile aphid viral vector. One useful control measure is to take advantage of the negative taxis
PerkinElmer (3,322 words) [view diff] exact match in snippet view article find links to article
the company announced it would acquire SIRION Biotech, a specialist in viral vector gene delivery methods. In July the business announced it would acquire
Optogenetics (11,915 words) [view diff] exact match in snippet view article find links to article
cells is challenging. A popular approach is to introduce an engineered viral vector that contains the optogenetic actuator gene attached to a specific promoter
Leaf Huang (297 words) [view diff] exact match in snippet view article find links to article
therapy and targeted drug delivery. He has pioneered the liposome non-viral vector and has designed and manufactured the cationic lipid vector for the first
Gene therapy in Parkinson's disease (1,819 words) [view diff] exact match in snippet view article find links to article
impact the development of the disease. There have been explored several viral vector-based gene delivery system that interfere with α- synuclein expression
Adherent culture (898 words) [view diff] exact match in snippet view article find links to article
"Adherent versus suspension based platforms: what is the near future of viral vector manufacturing?". BioInsights. Retrieved 2022-12-02. Kang, Wonmo; McNaughton
Onasemnogene abeparvovec (2,384 words) [view diff] exact match in snippet view article find links to article
transgene along with synthetic promoters. Upon administration, the AAV9 viral vector delivers the SMN1 transgene to the affected motor neurons, where it leads
Zoonosis (6,616 words) [view diff] exact match in snippet view article find links to article
attenuated vaccines. There are also new vaccine technologies such as viral vector vaccines and DNA/RNA Vaccines, which includes the SARS-CoV-2 Coronavirus
Genomic library (3,365 words) [view diff] exact match in snippet view article find links to article
above outlined steps. After a genomic library is constructed with a viral vector, such as lambda phage, the titer of the library can be determined. Calculating
Self-administration (3,793 words) [view diff] exact match in snippet view article find links to article
previously exposed to cocaine for extended periods. Animals infected with a viral vector overexpressing miR-212 in the dorsal striatum produced the same initial
Expression vector (4,178 words) [view diff] exact match in snippet view article find links to article
are being developed. The treatment is still a risky option due to the viral vector used which can cause ill-effects, for example giving rise to insertional
Suzanne Dickson (754 words) [view diff] exact match in snippet view article find links to article
studies in rats and transgenic mice and includes behavioural tasks, viral vector mapping, chemogenetics and RNAscope. Dickson is President and Executive
Sickle cell disease (14,970 words) [view diff] exact match in snippet view article find links to article
successfully treated in mice using gene therapy. The researchers used a viral vector to make the mice—which have essentially the same defect that causes human
Tablighi Jamaat (10,142 words) [view diff] exact match in snippet view article find links to article
Tablighi Jamaat event became India's worst coronavirus vector". "'Largest viral vector' — how Tablighi Jamaat spread coronavirus from Malaysia to India". 4
Diabrotica speciosa (1,545 words) [view diff] exact match in snippet view article find links to article
observed distances has been found. There is evidence that D. speciosa is a viral vector for comoviruses, southern bean mosaic virus, mimosa mosaic virus, tymoviruses
Sleeping Beauty transposon system (2,748 words) [view diff] exact match in snippet view article find links to article
Hackett PB (April 2011). "The Sleeping Beauty transposon system: a non-viral vector for gene therapy". Human Molecular Genetics. 20 (R1): R14–R20. doi:10
RNA silencing (5,475 words) [view diff] exact match in snippet view article find links to article
Species/formulation Packaging capacity Applications and considerations Viral vector Adenovirus Usually < 10 Kb dsDNA vector with large packaging capacity
George Church (geneticist) (6,630 words) [view diff] exact match in snippet view article
therapy with the new TLR9-edited Adeno-associated viruses (AAV) as a safer viral vector. Based on the research, Church and a postdoc from his lab who was also
Indiana University School of Medicine (8,594 words) [view diff] exact match in snippet view article find links to article
Clinical Cancer Center, and the only National Institute of Health-funded viral vector production facility for clinical grade therapeutics. The school is known
Microbubble (3,928 words) [view diff] exact match in snippet view article find links to article
macrophages do not engulf these particles. Microbubbles also serve a non-viral vector for gene transfection through electrostatic bonds between a positively
Polyvalent influenza vaccine (2,231 words) [view diff] exact match in snippet view article find links to article
with a baculovirus as a viral vector, which infects invertebrates. To guide the rapid HA antigen expression, the viral vector help deliver the flu HA
Glossary of cellular and molecular biology (M–Z) (19,756 words) [view diff] exact match in snippet view article
transduction The transfer of genetic material between cells by a virus or viral vector, either naturally or artificially. transfectant A cell which has undergone
Eocyte hypothesis (4,672 words) [view diff] exact match in snippet view article find links to article
into archaeal genomes. The transduction of genetic material through a viral vector led to an increase in complexity in the pre-eukaryotic cells. All these
Potato virus Y (5,658 words) [view diff] exact match in snippet view article find links to article
(Myzus persicae) has been found to be most effective in its role as viral vector, but others such as Aphis fabae, Aphis gossypii, Aphis nasturtii, Macrosiphum
Tetratricopeptide repeat protein 39B (1,318 words) [view diff] exact match in snippet view article find links to article
correlating with increased HDL-C. Knockdown of the mouse ortholog TTC39B via a viral vector (50% knockdown) resulted in significantly higher plasma HDL-C levels
Hippocampal replay (2,318 words) [view diff] exact match in snippet view article find links to article
previously injected bilaterally in the hippocampus with a recombinant viral vector containing an inhibitory designer receptor exclusively activated by a
Triatoma virus (2,484 words) [view diff] exact match in snippet view article find links to article
populations, and health concerns in humans, wild and domestic animals, viral vector controls are being investigated. Hesitations in early uses of Triatoma
Riccardo Cortese (2,833 words) [view diff] exact match in snippet view article find links to article
continued independent work in the further development and manufacture of viral vector-based therapeutics and vaccines. In 2015, Cortese founded a new company
Mavis Agbandje-McKenna (2,706 words) [view diff] exact match in snippet view article find links to article
to the patient's own immune system producing antibodies against the viral vector being used for treatment. Agbandje-McKenna and her colleagues at UF sought
Erythropoietin in neuroprotection (3,678 words) [view diff] exact match in snippet view article find links to article
inhibitor of wild type Epo from binding to its receptor. Though, the viral vector expressed R103-E Epo mutant was shown to be inhibitory to the progression
Science diplomacy and pandemics (9,834 words) [view diff] exact match in snippet view article find links to article
resulting in a variety of COVID-19 vaccines worldwide such as: DNA vaccine, viral vector vaccine, protein subunit vaccine, RNA vaccine, inactivated vaccine, and
David T. Curiel (1,653 words) [view diff] exact match in snippet view article find links to article
blood vessels in mice without affecting healthy tissues. His use of viral vector technology to optimize the immune system's response to vaccines earned
Murine respirovirus (31,225 words) [view diff] exact match in snippet view article find links to article
Kamada T, Takahara Y, Inoue M, et al. (November 2011). "Intranasal Sendai viral vector vaccination is more immunogenic than intramuscular under pre-existing