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Longer titles found: Thymidylate synthase (FAD) (view), Thymidylate synthase inhibitor (view)

searching for Thymidylate synthase 22 found (318 total)

alternate case: thymidylate synthase

DirectHit (1,366 words) [view diff] case mismatch in snippet view article find links to article

Antiestrogens/Estrogen Receptor, Taxanes/beta-tubulin III, 5FU/Thymidylate Synthase. In these trials DirectHit analysis of estrogen receptor and HER-2/neu
Macropodid alphaherpesvirus 1 (335 words) [view diff] exact match in snippet view article find links to article
Mahony TJ (2002). "Macropodid herpesvirus 1 encodes genes for both thymidylate synthase and ICP34.5". Virus Genes. 24 (3): 207–213. doi:10.1023/A:1015396430131
Bruce Donald (1,291 words) [view diff] exact match in snippet view article find links to article
the structure determination of the enzyme dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Cryptosporidium hominis, an important advancement
Cellular thermal shift assay (287 words) [view diff] exact match in snippet view article find links to article
Nordlund, Pär (2016-03-24). "CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil".
Pteridine reductase (262 words) [view diff] exact match in snippet view article find links to article
"The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major"
APBB2 (655 words) [view diff] exact match in snippet view article find links to article
precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression". J. Biol. Chem. 277 (38): 35481–8. doi:10.1074/jbc.M205227200
5-Ethynyl-2'-deoxyuridine (496 words) [view diff] exact match in snippet view article find links to article
Friedecký D, Adam T, Koberna K (2015-02-11). "A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity". PLOS ONE. 10 (2): e0117459
Searching the conformational space for docking (1,070 words) [view diff] exact match in snippet view article find links to article
Perry KM (March 1993). "Structure-based discovery of inhibitors of thymidylate synthase". Science. 259 (5100): 1445–50. Bibcode:1993Sci...259.1445S. doi:10
Trifluridine/tipiracil (1,067 words) [view diff] exact match in snippet view article find links to article
TF-TMP then covalently binds to tyrosine 146 of the active site of thymidylate synthase (TS) inhibiting the enzyme's activity. TS is vital to the synthesis
E2F (1,909 words) [view diff] exact match in snippet view article find links to article
CASP3,7,8, MAP3K5,14 Nucleotide synthesis: thymidine kinase (tk), thymidylate synthase (ts), DHFR DNA repair: BARD1, RAD51, UNG1,2, FANCA, FANCC, FANCJ
Biosynthesis (6,657 words) [view diff] exact match in snippet view article find links to article
methyl group onto the uracil base of dUMP to generate dTMP. The thymidylate synthase reaction, dUMP + 5,10-methylenetetrahydrofolate ⇔ dTMP + dihydrofolate
Proton-coupled folate transporter (2,648 words) [view diff] exact match in snippet view article find links to article
these properties. Pemetrexed, an antifolate inhibitor primarily of thymidylate synthase, is a good substrate for PCFT even at neutral pH as compared to other
APBB1 (1,455 words) [view diff] exact match in snippet view article find links to article
it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have
Osnat Penn (1,633 words) [view diff] case mismatch in snippet view article find links to article
(2010-03-01). "An Evolutionary Analysis of Lateral Gene Transfer in Thymidylate Synthase Enzymes". Systematic Biology. 59 (2): 212–225. doi:10.1093/sysbio/syp104
Polypurine reverse-Hoogsteen hairpin (1,551 words) [view diff] exact match in snippet view article find links to article
(July 2020). "Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins".
Hytrosaviridae (3,667 words) [view diff] exact match in snippet view article find links to article
drug is converted into active metabolites by the virally-encoded thymidylate synthase. The active metabolites subsequently block viral replication resulting
Helicoverpa zea nudivirus 2 (4,466 words) [view diff] exact match in snippet view article find links to article
Santi DV (June 1995). "The catalytic mechanism and structure of thymidylate synthase". Annual Review of Biochemistry. 64 (1): 721–62. doi:10.1146/annurev
Intron (5,693 words) [view diff] exact match in snippet view article find links to article
Chu F, Maley F (June 1985). "Processing of the intron-containing thymidylate synthase (td) gene of phage T4 is at the RNA level". Cell. 41 (2): 375–382
Wafik El-Deiry (3,588 words) [view diff] exact match in snippet view article find links to article
dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting". Scientific Reports. 7 (1): 9711. Bibcode:2017NatSR
ERCC1 (5,372 words) [view diff] exact match in snippet view article find links to article
Kim HJ (March 2007). "Prognostic value of expression of ERCC1, thymidylate synthase, and glutathione S-transferase P1 for 5-fluorouracil/oxaliplatin
Treatment of lung cancer (6,487 words) [view diff] exact match in snippet view article find links to article
Pemetrexed Pemetrexed functions as an antimetabolite. Pemetrexed inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase
Somatic evolution in cancer (9,909 words) [view diff] exact match in snippet view article find links to article
Galizia G, et al. (March 2004). "Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic