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Longer titles found: Thrombospondin-2 (view), Thrombospondin 1 (view), Thrombospondin 3 (view), Thrombospondin 4 (view)

searching for Thrombospondin 91 found (245 total)

ADAMTS10 (587 words) [view diff] exact match in snippet view article find links to article

A disintegrin and metalloproteinase with thrombospondin motifs 10 is an enzyme that in humans is encoded by the ADAMTS10 gene. This gene belongs to the

ADAMTS12 (539 words) [view diff] exact match in snippet view article find links to article

A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene. This gene encodes a member

ADAMTS2 (1,040 words) [view diff] exact match in snippet view article find links to article

A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS2) also known as procollagen I N-proteinase (PC I-NP) is an enzyme that in humans

ADAMTS9 (623 words) [view diff] exact match in snippet view article find links to article

A disintegrin and metalloproteinase with thrombospondin motifs 9 is an enzyme that in humans is encoded by the ADAMTS9 gene. This gene encodes a member

Brain-specific angiogenesis inhibitor 3 (542 words) [view diff] exact match in snippet view article find links to article

receptor that has a long N-terminus consisting of one cub domain, five BaI Thrombospondin type 1 repeats, and one hormone binding domain. BaI3 is expressed in

THSD1 (423 words) [view diff] exact match in snippet view article find links to article

Thrombospondin type-1 domain-containing protein 1 is a protein that in humans is encoded by the THSD1 gene. The protein encoded by this gene contains a

ADAMTSL1 (584 words) [view diff] exact match in snippet view article find links to article

resembling members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the propeptide region and the metalloproteinase

ADAMTS17 (727 words) [view diff] exact match in snippet view article find links to article

ADAM metallopeptidase with thrombospondin type 1 motif, 17 is a protein that in humans is encoded by the ADAMTS17 gene. This gene encodes a member of the

ADAMTS14 (148 words) [view diff] exact match in snippet view article find links to article

region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number

ADAMTS6 (392 words) [view diff] exact match in snippet view article find links to article

ADAM metallopeptidase with thrombospondin type 1 motif 6 is a protein that in humans is encoded by the ADAMTS6 gene. This gene encodes a member of the

CNTNAP2 (1,398 words) [view diff] exact match in snippet view article find links to article

F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein

ABT-510 (216 words) [view diff] exact match in snippet view article find links to article

Oncology, ABT-510 is a "subcutaneously (SC) administered nonapeptide thrombospondin analogue." Following inconclusive phase I clinical trials, a 2007 phase

SCO-spondin (621 words) [view diff] exact match in snippet view article find links to article

Dastugue B, Meiniel A (May 1996). "SCO-spondin: a new member of the thrombospondin family secreted by the subcommissural organ is a candidate in the modulation

CNTNAP4 (485 words) [view diff] exact match in snippet view article find links to article

type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. Alternative splicing results in two transcript

R-spondin 3 (483 words) [view diff] exact match in snippet view article find links to article

humans is encoded by the RSPO3 gene. This gene encodes a member of the thrombospondin type 1 repeat gene superfamily. In addition, the protein contains a

MiR-27b microRNA precursor (415 words) [view diff] exact match in snippet view article find links to article

disease. MiR-27b also targets Thrombospondin-1, an antiangiogenic protein. Reduction in miR-27b increases Thrombospondin-1 levels, which decreases angiogenesis

R-spondin 4 (545 words) [view diff] exact match in snippet view article find links to article

organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved

Collagen, type V, alpha 1 (1,067 words) [view diff] exact match in snippet view article find links to article

PMID 6501291. Mumby SM, Raugi GJ, Bornstein P (1984). "Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen"

B3GALTL (518 words) [view diff] exact match in snippet view article find links to article

the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain". Glycobiology. 16 (12): 1194–1206. doi:10.1093/glycob/cwl035

MTX1 (723 words) [view diff] exact match in snippet view article find links to article

S, Vos HL, Ginns EI (May 1995). "Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the

SEMA5A (587 words) [view diff] exact match in snippet view article find links to article

(June 1996). "A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis". Mechanisms

Chromosome 21 (2,969 words) [view diff] exact match in snippet view article find links to article

metalloproteinase with thrombospondin motifs 1 ADAMTS5: encoding enzyme a disintegrin and metalloproteinase with thrombospondin motifs 5 ADARB1: encoding

NELL2 (479 words) [view diff] exact match in snippet view article find links to article

extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins". J. Mol. Biol. 275 (5):

CCN protein (750 words) [view diff] exact match in snippet view article find links to article

domain (IGFBP), the Von Willebrand factor type C domain (VWC), the thrombospondin type 1 repeat (TSR), and a C-terminal domain (CT) with a cysteine knot

Membranous glomerulonephritis (2,291 words) [view diff] exact match in snippet view article find links to article

PLA2R autoantibodies. In 2014, a second autoantigen was discovered, the thrombospondin type 1 domain-containing 7A (THSD7A) system that might account for an

Fibroblast (1,677 words) [view diff] exact match in snippet view article find links to article

common. Examples of TAF-derived ECM components include Tenascin and Thrombospondin-1 (TSP-1), which can be found in sites of chronic inflammation and carcinomas

60S ribosomal protein L36a (782 words) [view diff] exact match in snippet view article find links to article

of a cDNA encoding the heparin and collagen binding domains of human thrombospondin". Proc Natl Acad Sci U S A. 83 (15): 5449–53. Bibcode:1986PNAS...83

Apadamtase alfa (407 words) [view diff] exact match in snippet view article find links to article

alfa is a human recombinant a disintegrin and metalloproteinase with thrombospondin motifs 13. It is given by injection into a vein. The most common side

ADAM (protein) (669 words) [view diff] exact match in snippet view article

anti-cancer therapy. ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs) family Ectodomain shedding Brocker, C; Vasiliou, V; Nebert,

Brain-specific angiogenesis inhibitor 1 (1,207 words) [view diff] exact match in snippet view article find links to article

(Oct 1997). "A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis". Oncogene. 15 (18):

Peters-plus syndrome (769 words) [view diff] exact match in snippet view article find links to article

caused by a defect in the beta1,3-glucosyltransferase that modifies thrombospondin type 1 repeats". Annals of Medicine. 41 (1): 2–10. doi:10.1080/07853890802301975

Integrin beta 6 (4,041 words) [view diff] exact match in snippet view article find links to article

TGF-β1 can still be activated by other proteins such as Thrombospondin-1. In itgb6/thrombospondin 1 (tsp-1) double-null mice, there is a higher incidence

PAPLN (320 words) [view diff] exact match in snippet view article find links to article

2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol

Chromosome 9 (1,594 words) [view diff] exact match in snippet view article find links to article

protein Actin-like protein 7A ADAMTS13: ADAM metallopeptidase with thrombospondin type 1 motif, 13 AIF1L: allograft inflammatory factor 1-like ALAD: aminolevulinate

Hennekam syndrome (473 words) [view diff] exact match in snippet view article find links to article

Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular Endothelial Growth Factor-C Activation".

Laminin, beta 3 (1,004 words) [view diff] exact match in snippet view article find links to article

(1999). "Two-hybrid analysis reveals multiple direct interactions for thrombospondin 1". Matrix Biol. 17 (6): 401–12. doi:10.1016/S0945-053X(98)90100-7.

Alpha-actinin-1 (1,374 words) [view diff] exact match in snippet view article find links to article

"Identification of the cytoskeletal protein alpha-actinin as a platelet thrombospondin-binding protein". FEBS Lett. 364 (2): 109–14. doi:10.1016/0014-5793(95)00362-D

CTGF (1,537 words) [view diff] exact match in snippet view article find links to article

(IGFBP) domain, the von Willebrand type C repeats (vWC) domain, the thrombospondin type 1 repeat (TSR) domain, and a C-terminal domain (CT) with a cysteine

Von Willebrand factor (2,069 words) [view diff] exact match in snippet view article find links to article

enzyme ADAMTS13 (acronym of "a disintegrin-like and metalloprotease with thrombospondin type 1 motif no. 13"). It is a metalloproteinase that cleaves VWF between

Chromosome 5 (2,298 words) [view diff] exact match in snippet view article find links to article

protein Actin-binding LIM protein 3 ADAMTS2: ADAM metallopeptidase with thrombospondin type 1 motif, 2 AGXT2: Alanine-glyoxylate aminotransferase 2 ANKRD31:

Multiple epiphyseal dysplasia (2,399 words) [view diff] exact match in snippet view article find links to article

MED. Lack of COMP was not compensated for by any other protein in the thrombospondin family. This study confirmed that the disease is not caused by reduced

WNT1-inducible-signaling pathway protein 3 (625 words) [view diff] exact match in snippet view article find links to article

factor binding protein (IGFBP), von Willebrand type C repeats (vWC), thrombospondin type 1 repeat (TSR), and a cysteine knot motif within the C-terminal

CCBE1 (702 words) [view diff] exact match in snippet view article find links to article

Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3-Mediated Vascular Endothelial Growth Factor-C Activation".

N-Feruloylserotonin (620 words) [view diff] exact match in snippet view article find links to article

metalloproteinases MMP3/13 and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), thus attenuating cartilage degradation. The biosynthetic

Muskelin (538 words) [view diff] exact match in snippet view article find links to article

intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1". EMBO J. 17 (17): 4964–74. doi:10.1093/emboj/17.17.4964. PMC 1170825

SCARB2 (2,546 words) [view diff] exact match in snippet view article find links to article

Smits JF, Daemen MJ, Crijns HJ, Bornstein P, Pinto YM (Sep 2004). "Thrombospondin-2 is essential for myocardial matrix integrity: increased expression

Gamma-glutamyltransferase 7 (368 words) [view diff] exact match in snippet view article find links to article

a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain". The Journal of Biological Chemistry

Peptide-O-fucosyltransferase (270 words) [view diff] exact match in snippet view article find links to article

Peter-Katalinic, J (2001). "C-mannosylation and O-fucosylation of the thrombospondin type 1 module". J. Biol. Chem. 276 (9): 6485–98. doi:10.1074/jbc.M008073200

Vascular endothelial growth factor C (3,104 words) [view diff] exact match in snippet view article find links to article

enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation".

NOV (gene) (1,878 words) [view diff] exact match in snippet view article

factor binding protein (IGFBP), von Willebrand type C repeats (vWC), thrombospondin type 1 repeat (TSR), and a cysteine knot motif within the C-terminal

Gabapentinoid (4,035 words) [view diff] exact match in snippet view article find links to article

Mosher DF, Barres BA (2009). "Gabapentin Receptor α2δ-1 is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis". Cell. 139 (2):

Jeffery D. Molkentin (960 words) [view diff] exact match in snippet view article find links to article

V; Nahrendorf, M; Sadayappan, S; et al. Nature. 2020; 577:405-409. A thrombospondin-dependent pathway for a protective ER stress response. Lynch, J. M.

MIR194-1 (552 words) [view diff] exact match in snippet view article find links to article

OV, Thomas-Tikhonenko A (Dec 2011). "p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers". Cancer Research. 71 (24):

Laminin (3,429 words) [view diff] exact match in snippet view article find links to article

neurexins (NRXN1, NRXN2, NRXN3), slit homologs (SLIT1, SLIT2, SLIT3), thrombospondins (THBS1, THBS2, THBS3, THBS4, TSPEAR), agrin (AGRIN), chondroitin sulfate

LRP5 (3,205 words) [view diff] exact match in snippet view article find links to article

lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1". The Journal of Cell Biology. 129 (5): 1403–10. doi:10.1083/jcb.129

Multimerin 1 (899 words) [view diff] exact match in snippet view article find links to article

associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation

Carla F. Kim (750 words) [view diff] exact match in snippet view article find links to article

differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis". Cell. 156 (3): 440–455. doi:10.1016/j.cell.2013.12.039. ISSN 1097-4172

Photoaging (2,292 words) [view diff] exact match in snippet view article find links to article

radiation would cause the down-regulation of an angiogenesis inhibitor, thrombospondin-1, and the up-regulation of an angiogenesis activator which is platelet-derived

Dihydrofolate reductase (4,581 words) [view diff] exact match in snippet view article find links to article

Vanguri VK, Wang S, Godyna S, Ranganathan S, Liau G (April 2000). "Thrombospondin-1 binds to polyhistidine with high affinity and specificity". The Biochemical

Fascin (1,556 words) [view diff] exact match in snippet view article find links to article

Roh MS (March 2009). "Fascin overexpression correlates with positive thrombospondin-1 and syndecan-1 expressions and a more aggressive clinical course in

List of human clusters of differentiation (467 words) [view diff] exact match in snippet view article find links to article

bone marrow cells. Receptor for collagen, laminin, fibronectin, and thrombospondin. CD49d Integrin alpha 4 subunit. Unlike other integrin alpha chains

WNT1-inducible-signaling pathway protein 1 (1,324 words) [view diff] exact match in snippet view article find links to article

factor binding protein (IGFBP), von Willebrand type C repeats (vWC), thrombospondin type 1 repeat (TSR), and a cysteine knot motif within the C-terminal

Reelin (15,715 words) [view diff] exact match in snippet view article find links to article

of Reelin, most likely by the influence of a newly proposed ligand, thrombospondin-1. In the adult dentate gyrus, reelin provides guidance cues for new

Thrombin (2,932 words) [view diff] exact match in snippet view article find links to article

hydrolase activity growth factor activity serine-type peptidase activity thrombospondin receptor activity protein binding serine-type endopeptidase activity

Haptotaxis (2,092 words) [view diff] exact match in snippet view article find links to article

Hutcheon, Audrey E.K; Zieske, James D. (January 28, 2013). "Role of Thrombospondin-1 in Repair of Penetrating Corneal Wounds". Investigative Ophthalmology

Aryl hydrocarbon receptor (5,962 words) [view diff] exact match in snippet view article find links to article

activators include proteases such as plasmin, cathepsins, and calpains. Thrombospondin 1, a glycoprotein that inhibits angiogenesis, and matrix metalloproteinase

Upshaw–Schulman syndrome (3,483 words) [view diff] exact match in snippet view article find links to article

ECG changes). The ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif 13) gene is located on chromosome 9q34 and encoding 29

Von Willebrand factor type A domain (791 words) [view diff] exact match in snippet view article find links to article

Willebrand factor type a domains? Sequence similarities with malaria thrombospondin-related anonymous protein, dihydropyridine-sensitive calcium channel

Tasquinimod (1,511 words) [view diff] exact match in snippet view article find links to article

quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors". Molecular Cancer. 9: 107. doi:10.1186/1476-4598-9-107

Macrophage (10,188 words) [view diff] exact match in snippet view article find links to article

state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice". PLOS ONE. 3 (12): e3950. Bibcode:2008PLoSO...3.3950B

Raymond L. Rodriguez (3,788 words) [view diff] exact match in snippet view article find links to article

M.M.J. Dawson, K. R. L. Rodriguez. 2011. Differential Expression of Thrombospondin (THBS1) in Turmorigenic and Nontumorigenic Prostate Epithelial Cells

Syndecan (2,370 words) [view diff] exact match in snippet view article find links to article

extracellular matrix molecules such as collagens I, III, V, fibronectin, thrombospondin, and tenascin to provide structural support for the adhesion [1, 2]

CORO1A (1,777 words) [view diff] exact match in snippet view article find links to article

S2CID 18159353. Vanguri VK, Wang S, Godyna S, Ranganathan S, Liau G (Apr 2000). "Thrombospondin-1 binds to polyhistidine with high affinity and specificity". The Biochemical

Plasmodium falciparum (9,982 words) [view diff] exact match in snippet view article find links to article

hepatocytes. Binding to and entering into the hepatocytes is aided by thrombospondin-related anonymous protein (TRAP). TRAP and other secretory proteins

Syndecan-4 (2,088 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function fibronectin binding protein binding thrombospondin receptor activity protein kinase C binding identical protein binding

MYH9 (6,346 words) [view diff] exact match in snippet view article find links to article

nonmuscle myosin heavy chain-A, and focal adhesion kinase from in thrombospondin-treated smooth muscle cells". Journal of Investigative Medicine. 48

Role of cell adhesions in neural development (1,859 words) [view diff] exact match in snippet view article find links to article

subcellular localization, and fibroblast migration, in response to thrombospondin-1/hep I". Chronology. 312 (19): 3752–3767. doi:10.1016/j.yexcr.2006

SNED1 (2,400 words) [view diff] exact match in snippet view article find links to article

Collagens with Interrupted triple-helices (FACITS), all containing a thrombospondin domain, COL12A1, COL14A1, COL16A1, COL20A1); and a number of ECM glycoproteins:

Michael Jeltsch (759 words) [view diff] exact match in snippet view article find links to article

Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular Endothelial Growth Factor-C Activation".

Induced stem cells (25,002 words) [view diff] exact match in snippet view article find links to article

approach to CRC is to inhibit CD47 – a membrane protein that is the thrombospondin-1 receptor. Loss of CD47 permits sustained proliferation of primary

CYR61 (4,894 words) [view diff] exact match in snippet view article find links to article

protein (IGFBP) domain, von Willebrand type C repeats (vWC) domain, thrombospondin type 1 repeat domain (TSR), and the C-terminal (CT) domain that contains

UNC-5 (2,577 words) [view diff] exact match in snippet view article find links to article

(October 1992). "UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans"

VLDL receptor (4,708 words) [view diff] exact match in snippet view article find links to article

(apoB), which is present in LDL. Receptor-associated protein (RAP) and thrombospondin-1 (THBS1) have been identified as compounds that bind VLDLR. In many

Organoid (9,321 words) [view diff] exact match in snippet view article find links to article

differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis". Cell. 156 (3): 440–55. doi:10.1016/j.cell.2013.12.039. PMC 3951122

UNC (biology) (2,673 words) [view diff] exact match in snippet view article

G. (1992). "UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. Elegans"

Christian Bréchot (2,258 words) [view diff] exact match in snippet view article find links to article

and MF Bourgeade. HCV core-mediated activation of latent TGF-β via thrombospondin drives the cross-talk between hepatocytes and stromal environment. J

George Stouffer (1,887 words) [view diff] exact match in snippet view article find links to article

"Beta3 integrins are upregulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells"

Perlecan (11,011 words) [view diff] exact match in snippet view article find links to article

development due to greatly increased expression of perlecan, fibronectin and thrombospondin-1 in the corneal mesenchyme. The effect was more pronounced in the βB-1

A. Mark Richards (2,610 words) [view diff] exact match in snippet view article find links to article

"microRNA-221 Inhibits Latent TGF-β1 Activation through Targeting Thrombospondin-1 to Attenuate Kidney Failure-Induced Cardiac Fibrosis". Molecular Therapy

Stem-cell niche (8,002 words) [view diff] exact match in snippet view article find links to article

angiogenic switch downregulates angiogenesis suppressor proteins, such as thrombospondin, angiostatin, endostatin and tumstatin. Angiogenesis is necessary for

Russell J. Howard (2,518 words) [view diff] exact match in snippet view article find links to article

Howard, R. J. (5 September 1992). "CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction". Journal