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Longer titles found: Small GTPases (journal) (view)

searching for Small GTPase 308 found (367 total)

RHOBTB1 (522 words) [view diff] exact match in snippet view article find links to article

domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament

RAC3 (1,412 words) [view diff] exact match in snippet view article find links to article

Haataja L, Kaartinen V, Groffen J, Heisterkamp N (March 2002). "The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin

RRAD (gene) (950 words) [view diff] exact match in snippet view article

protein that in humans is encoded by the RRAD gene. RRAD is a Ras-related small GTPase that is regulated by p53 and plays a role in the regulation of aerobic

CEACAM3 (932 words) [view diff] exact match in snippet view article find links to article

directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific

RAB7A (2,313 words) [view diff] exact match in snippet view article find links to article

the Retromer Complex, most likely through the Vps35 subunit. RAB7 is a small GTPase that has the potential of causing malignancy from over 35 tumor types

Arfaptin (172 words) [view diff] exact match in snippet view article find links to article

the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory

RAB2B (981 words) [view diff] exact match in snippet view article find links to article

from the endoplasmic reticulum to the Golgi complex. It belongs to the small GTPase superfamily, specifically to the RAB protein family. Small GTPases are

RHOBTB2 (723 words) [view diff] exact match in snippet view article find links to article

cell projection Biological process regulation of small GTPase mediated signal transduction small GTPase mediated signal transduction cell morphogenesis

ROCK1 (2,273 words) [view diff] exact match in snippet view article find links to article

names are ROKβ and P160ROCK. ROCK1 is a major downstream effector of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes

Cytotoxic necrotising factor family (276 words) [view diff] exact match in snippet view article find links to article

fibres and focal adhesions by deamidating or polyaminating Gln63 of the small GTPase Rho. DNT is an A-B toxin composed of an N-terminal receptor-binding (B)

WASL (gene) (1,310 words) [view diff] exact match in snippet view article

demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal

RAB33A (437 words) [view diff] exact match in snippet view article find links to article

by the RAB33A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved

RAB5A (1,473 words) [view diff] exact match in snippet view article find links to article

Ullrich O, Zerial M (Nov 1995). "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion". Cell. 83 (3): 423–32. doi:10

TSC2 (1,843 words) [view diff] exact match in snippet view article find links to article

KL (September 2004). "Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity". Molecular and Cellular Biology. 24 (18):

Rubicon homology domain (441 words) [view diff] exact match in snippet view article find links to article

characterized, those of human Rubicon and PLEKHM1 mediate interaction with the small GTPase Rab7, which is found on late endosomes and autophagosomes. RH domains

TWF1 (466 words) [view diff] exact match in snippet view article find links to article

localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. GRCh38: Ensembl release 89: ENSG00000151239 – Ensembl, May 2017

RAP1B (982 words) [view diff] exact match in snippet view article find links to article

PMID 17318188. Carmona G, Göttig S, Orlandi A, et al. (2009). "Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis"

FGD3 (497 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function metal ion binding small GTPase binding guanyl-nucleotide exchange factor activity Cellular component cytoplasm cytosol

FGD4 (463 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function metal ion binding small GTPase binding actin binding guanyl-nucleotide exchange factor activity Cellular component cytoplasm

PLEKHG2 (1,151 words) [view diff] exact match in snippet view article find links to article

guanine nucleotide exchange activity that converts GDP on the Rho family Small GTPase (RhoGTPase) to GTP, and PLEKHG2 having this domain also acts as a Rho-specific

RHOQ (1,273 words) [view diff] exact match in snippet view article find links to article

Masayoshi, Miki Hiroaki, Takenawa Tadaomi, Endo Takeshi (January 2003). "Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation

SNX26 (537 words) [view diff] exact match in snippet view article find links to article

regulation of small GTPase mediated signal transduction protein transport positive regulation of GTPase activity signal transduction small GTPase mediated

FGD2 (523 words) [view diff] exact match in snippet view article find links to article

Molecular function phosphatidylinositol phosphate binding metal ion binding small GTPase binding protein binding guanyl-nucleotide exchange factor activity Cellular

RAB11A (1,394 words) [view diff] exact match in snippet view article find links to article

by the RAB11A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and

Rabaptin (432 words) [view diff] exact match in snippet view article find links to article

a 100kDa coiled-coil protein that interacts with the GTP form of the small GTPase Rab5 (see RAB5A, RAB5B, RAB5C) a potent regulator of endocytic transport

BCR (gene) (1,541 words) [view diff] exact match in snippet view article

pathway regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction negative regulation of inflammatory response

Pacer (protein) (622 words) [view diff] exact match in snippet view article

Rubicon homology (RH) domain at its C-terminus, which mediates binding to small GTPase Rab7. This domain is shared with RH domain containing family members

GDI2 (928 words) [view diff] exact match in snippet view article find links to article

activity regulation of small GTPase mediated signal transduction vesicle-mediated transport signal transduction small GTPase mediated signal transduction

ARF4 (1,002 words) [view diff] exact match in snippet view article find links to article

Lo JF, Yang Y, Yoo JS, Lee JD (Jan 2003). "ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2

RAB4A (1,214 words) [view diff] exact match in snippet view article find links to article

L, Van Der Sluijs P (Mar 2000). "Rabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesicles". The Biochemical

ARHGAP1 (1,284 words) [view diff] exact match in snippet view article find links to article

ZX, Zheng Y (1997). "Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison

RAPGEF4 (2,724 words) [view diff] exact match in snippet view article find links to article

Epac2 functions as a guanine nucleotide exchange factor for the Ras-like small GTPase Rap upon cAMP stimulation. Epac2 is involved in a variety of cAMP-mediated

DYNC1LI1 (456 words) [view diff] exact match in snippet view article find links to article

PMID 10893222. Bielli A, Thörnqvist PO, Hendrick AG, et al. (2001). "The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate

ARL8A (249 words) [view diff] exact match in snippet view article find links to article

Araki Y, Tada M, Tateno T, Kontani K, Katada T (September 2004). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome

ARL13B (504 words) [view diff] exact match in snippet view article find links to article

of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding

RAB7B (411 words) [view diff] exact match in snippet view article find links to article

is a protein that in humans is encoded by the RAB7B gene. Rab7 is a small GTPase that plays a role in the transport and degradation of proteins in endosomes

Lysophosphatidic acid (708 words) [view diff] exact match in snippet view article find links to article

(impaired bile flow) diseases. Downstream of LPA receptor activation, the small GTPase Rho can be activated, subsequently activating Rho kinase. This can lead

RAB6B (504 words) [view diff] exact match in snippet view article find links to article

de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (August 2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed

SRGAP1 (466 words) [view diff] exact match in snippet view article find links to article

transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10

RALA (2,012 words) [view diff] exact match in snippet view article find links to article

Ohta Y, Suzuki N, Nakamura S, Hartwig JH, Stossel TP (Mar 1999). "The small GTPase RalA targets filamin to induce filopodia". Proceedings of the National

Citron kinase (2,469 words) [view diff] exact match in snippet view article find links to article

actomyosin filaments are continuously assembled and disassembled. The small GTPase RhoA has been shown to be implicated, controlling CR assembly and dynamics

SRGAP3 (580 words) [view diff] exact match in snippet view article find links to article

transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10

RAB17 (683 words) [view diff] exact match in snippet view article find links to article

PMID 8125298. Lütcke A, Jansson S, Parton RG, et al. (1993). "Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization"

RAP1GDS1 (576 words) [view diff] exact match in snippet view article find links to article

PMID 12477932. de Bruyn KM, Zwartkruis FJ, de Rooij J, et al. (2003). "The small GTPase Rap1 is activated by turbulence and is involved in integrin [alpha]IIb[beta]3-mediated

MCF2L (681 words) [view diff] exact match in snippet view article find links to article

exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1". The Journal of Biological Chemistry. 282 (32): 23296–305. doi:10

PLEKHG5 (380 words) [view diff] exact match in snippet view article find links to article

encodes a protein which catalyzes the exchange of GDP for GTP within the small GTPase RhoA which in turn modulates the activation of mDia or Rock kinase to

FLNA (1,890 words) [view diff] exact match in snippet view article find links to article

Ohta Y, Suzuki N, Nakamura S, Hartwig JH, Stossel TP (March 1999). "The small GTPase RalA targets filamin to induce filopodia". Proc. Natl. Acad. Sci. U.S

ARL8B (569 words) [view diff] exact match in snippet view article find links to article

PMC 528928. PMID 15489334. Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome

ARHGAP31 (746 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction small GTPase mediated signal transduction Sources:Amigo

ARHGAP25 (265 words) [view diff] exact match in snippet view article find links to article

of small GTPase mediated signal transduction signal transduction phagocytosis, engulfment actin filament organization negative regulation of small GTPase

KIF20A (945 words) [view diff] exact match in snippet view article find links to article

van de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed

GPSM2 (677 words) [view diff] exact match in snippet view article find links to article

adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras". Mol. Cell. Biol. 23 (11): 3847–58. doi:10.1128/MCB.23.11.3847-3858

RHOJ (457 words) [view diff] exact match in snippet view article find links to article

cytoplasm cell cortex cell projection Biological process regulation of small GTPase mediated signal transduction retina vasculature morphogenesis in camera-type

TSC1 (2,424 words) [view diff] exact match in snippet view article find links to article

signaling by functioning as a GTPase-activating protein (GAP) for the small GTPase Rheb, an essential activator of mTORC1. The TSC complex has been implicated

RAB1B (893 words) [view diff] exact match in snippet view article find links to article

"The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b". EMBO Rep. 2 (4). England: 336–41. doi:10.1093/embo-reports/kve065

RASGRF2 (607 words) [view diff] exact match in snippet view article find links to article

of Rho protein signal transduction regulation of small GTPase mediated signal transduction small GTPase mediated signal transduction response to endoplasmic

OCRL (1,047 words) [view diff] exact match in snippet view article find links to article

dephosphorylation phosphatidylinositol biosynthetic process regulation of small GTPase mediated signal transduction signal transduction positive regulation

VAV2 (1,055 words) [view diff] exact match in snippet view article find links to article

transduction regulation of small GTPase mediated signal transduction cell migration signal transduction lamellipodium assembly small GTPase mediated signal transduction

SRGAP2 (780 words) [view diff] exact match in snippet view article find links to article

transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10

VAV3 (799 words) [view diff] exact match in snippet view article find links to article

activity vascular endothelial growth factor receptor signaling pathway small GTPase mediated signal transduction B cell receptor signaling pathway cell projection

Intersectin 1 (1,238 words) [view diff] exact match in snippet view article find links to article

of Rho protein signal transduction regulation of small GTPase mediated signal transduction small GTPase mediated signal transduction membrane organization

GRB2-associated-binding protein 1 (1,611 words) [view diff] exact match in snippet view article find links to article

"Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL"

GEM (gene) (663 words) [view diff] exact match in snippet view article

CRYSTAL STRUCTURE OF THE SMALL GTPASE GEM (GEMDNDCAM) IN COMPLEX TO MG.GDP 2g3y: Crystal structure of the human small GTPase GEM 2ht6: Crystal structure

RCC2 (733 words) [view diff] exact match in snippet view article find links to article

to have weak guanine nucleotide exchange factor (GEF) activity on the small GTPase Rac. TD-60 has also been shown to interact with the Chromosomal Passenger

SOS1 (3,595 words) [view diff] exact match in snippet view article find links to article

morphogenesis regulation of T cell proliferation positive regulation of small GTPase mediated signal transduction blood vessel morphogenesis epidermal growth

RALBP1 (1,239 words) [view diff] exact match in snippet view article find links to article

component cytosol membrane Biological process endocytosis regulation of small GTPase mediated signal transduction transmembrane transport regulation of GTPase

Bikont (703 words) [view diff] exact match in snippet view article find links to article

Romana; Tachezy, Jan (2016). "A paneukaryotic genomic analysis of the small GTPase RABL2 underscores the significance of recurrent gene loss in eukaryote

GPR97 (850 words) [view diff] exact match in snippet view article find links to article

cytoskeletal rearrangement, cell adhesion and migration through regulating the small GTPase RhoA and cdc42. In vertebrates, GPR97 has an indispensable role in the

RABEP1 (1,213 words) [view diff] exact match in snippet view article find links to article

Ullrich O, Zerial M (Nov 1995). "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion". Cell. 83 (3): 423–32. doi:10

IMD domain (682 words) [view diff] exact match in snippet view article find links to article

and bundle actin filaments, bind to membranes and interact with the small GTPase Rac. The IMD domain folds as a coiled coil of three extended alpha-helices

VAV1 (1,999 words) [view diff] exact match in snippet view article find links to article

pathway regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction positive regulation of natural killer cell

RILP (gene) (764 words) [view diff] exact match in snippet view article

Hong W, Song H (2005). "Structural basis for recruitment of RILP by small GTPase Rab7". EMBO J. 24 (8): 1491–501. doi:10.1038/sj.emboj.7600643. PMC 1142575

MYO9B (855 words) [view diff] exact match in snippet view article find links to article

activity regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction signal transduction Rho protein signal transduction

FGD1 (1,606 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function metal ion binding small GTPase binding guanyl-nucleotide exchange factor activity Cellular component cytoplasm Golgi apparatus

RAP1GAP (998 words) [view diff] exact match in snippet view article find links to article

KM, Rangarajan S, Reedquist KA, Figdor CG, Bos JL (August 2002). "The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated

RAPGEF1 (1,640 words) [view diff] exact match in snippet view article find links to article

"Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL"

Golgin subfamily A member 2 (1,705 words) [view diff] exact match in snippet view article find links to article

"The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b". EMBO Reports. 2 (4): 336–41. doi:10.1093/embo-reports/kve065

GDI1 (1,241 words) [view diff] exact match in snippet view article find links to article

regulation of catalytic activity regulation of small GTPase mediated signal transduction signal transduction small GTPase mediated signal transduction positive

Dedicator of cytokinesis protein 1 (2,406 words) [view diff] exact match in snippet view article find links to article

Retrieved 2020-09-13. Katoh H, Yasui H, Yamaguchi Y, et al. (October 2000). "Small GTPase RhoG Is a Key Regulator for Neurite Outgrowth in PC12 Cells". Mol. Cell

HMOX1 (679 words) [view diff] exact match in snippet view article find links to article

transcription from RNA polymerase II promoter in response to oxidative stress small GTPase mediated signal transduction negative regulation of DNA binding response

Wiskott–Aldrich syndrome protein (2,588 words) [view diff] exact match in snippet view article find links to article

proteins. These proteins, directly or indirectly, associate with the small GTPase CDC42, known to regulate formation of actin filaments, and the cytoskeletal

RICS (gene) (1,849 words) [view diff] exact match in snippet view article

regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction small GTPase mediated signal transduction Sources:Amigo

TRIO (gene) (1,025 words) [view diff] exact match in snippet view article

process regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction negative regulation of fat cell differentiation

RALB (1,603 words) [view diff] exact match in snippet view article find links to article

Iwamatsu A, Okawa K, Ohta Y (2002). "The exocyst complex binds the small GTPase RalA to mediate filopodia formation". Nat. Cell Biol. 4 (1): 73–8. doi:10

GRLF1 (819 words) [view diff] exact match in snippet view article find links to article

development negative regulation of transcription, DNA-templated regulation of small GTPase mediated signal transduction signal transduction negative regulation

ARHGAP44 (131 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction exocytosis regulation

ARL15 (75 words) [view diff] exact match in snippet view article find links to article

extracellular exosome intracellular anatomical structure Biological process small GTPase mediated signal transduction biological process Sources:Amigo / QuickGO

Giantin (1,627 words) [view diff] exact match in snippet view article find links to article

Alexey; Barnekow, Angelika (July 2007). "Giantin interacts with both the small GTPase Rab6 and Rab1". Experimental Cell Research. 313 (11): 2318–2325. doi:10

Formyl peptide receptor (1,417 words) [view diff] exact match in snippet view article find links to article

is an inducer of protein kinase C (PKC). Activation of the regulatory small GTPase, RAS. The active RAS can in turn activate RAF, a Ser/Thr kinase. In the

Abr, rhogef and gtpase activating protein (556 words) [view diff] exact match in snippet view article find links to article

intracellular signal transduction neuromuscular process controlling balance small GTPase mediated signal transduction negative regulation of blood vessel remodeling

DYNLL1 (1,545 words) [view diff] exact match in snippet view article find links to article

PO, Hendrick AG, Finn R, Fitzgerald K, McCaffrey MW (Mar 2001). "The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate

Filopodia (1,172 words) [view diff] exact match in snippet view article find links to article

Ohta Y, Suzuki N, Nakamura S, Hartwig JH, Stossel TP (March 1999). "The small GTPase RalA targets filamin to induce filopodia". Proceedings of the National

RACGAP1 (1,608 words) [view diff] exact match in snippet view article find links to article

et al. (December 2001). "Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation". Cell Structure and

Dedicator of cytokinesis protein 5 (562 words) [view diff] exact match in snippet view article find links to article

component plasma membrane membrane cytoplasm cytosol Biological process small GTPase mediated signal transduction negative regulation of vascular associated

Mycoplasma (5,460 words) [view diff] exact match in snippet view article find links to article

Another possible mechanism of carcinogenesis is RAC1 activation by a small GTPase-like protein fragment of Mycoplasma. A major feature that differentiates

Dedicator of cytokinesis protein 6 (556 words) [view diff] exact match in snippet view article find links to article

perinuclear region of cytoplasm cytoplasm cytosol Biological process small GTPase mediated signal transduction blood coagulation Sources:Amigo / QuickGO

Dedicator of cytokinesis protein 10 (636 words) [view diff] exact match in snippet view article find links to article

nucleoplasm cytosol intracellular anatomical structure Biological process small GTPase mediated signal transduction regulation of cell migration B cell homeostasis

ALS2 (905 words) [view diff] exact match in snippet view article find links to article

et al. (2003). "ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics". Hum. Mol. Genet. 12 (14):

ARL13A (77 words) [view diff] exact match in snippet view article find links to article

structure cilium ciliary membrane non-motile cilium Biological process small GTPase mediated signal transduction receptor localization to non-motile cilium

CHML (gene) (753 words) [view diff] exact match in snippet view article

transport protein geranylgeranylation regulation of catalytic activity small GTPase mediated signal transduction post-translational protein modification

RAB35 (334 words) [view diff] exact match in snippet view article find links to article

mitotic cytokinesis intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

KIF23 (1,849 words) [view diff] exact match in snippet view article find links to article

Nosaka T (December 2001). "Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation". Cell Struct. Funct

PRKCI (1,731 words) [view diff] exact match in snippet view article find links to article

recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase

RERG (127 words) [view diff] exact match in snippet view article find links to article

response to hormone negative regulation of cell growth signal transduction small GTPase mediated signal transduction Ras protein signal transduction Sources:Amigo

PRKCI (1,731 words) [view diff] exact match in snippet view article find links to article

recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase

RERG (127 words) [view diff] exact match in snippet view article find links to article

response to hormone negative regulation of cell growth signal transduction small GTPase mediated signal transduction Ras protein signal transduction Sources:Amigo

Bacterial translation (2,920 words) [view diff] exact match in snippet view article find links to article

bind. This binding is facilitated by elongation factor-Tu (EF-Tu), a small GTPase. For fast and accurate recognition of the appropriate tRNA, the ribosome

ARHGEF4 (469 words) [view diff] exact match in snippet view article find links to article

signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction lamellipodium assembly positive regulation

SIPA1L2 (394 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction biological process Sources:Amigo / QuickGO

CIB1 (2,206 words) [view diff] exact match in snippet view article find links to article

Haataja L, Kaartinen Vesa, Groffen John, Heisterkamp Nora (Mar 2002). "The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin

NKIRAS2 (275 words) [view diff] exact match in snippet view article find links to article

M, Mizuno N, Itoh H (Oct 2010). "KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional

TTC1 (479 words) [view diff] exact match in snippet view article find links to article

adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras". Mol. Cell. Biol. 23 (11): 3847–58. doi:10.1128/MCB.23.11.3847-3858

ARHGEF3 (551 words) [view diff] exact match in snippet view article find links to article

signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction Rho protein signal transduction positive

HMHA1 (729 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity intracellular signal transduction regulation of small GTPase mediated signal transduction signal transduction neutrophil degranulation

FRMD7 (672 words) [view diff] exact match in snippet view article find links to article

growth cone extracellular space Biological process positive regulation of small GTPase mediated signal transduction negative regulation of stress fiber assembly

RABIF (531 words) [view diff] exact match in snippet view article find links to article

Cellular component cytosol membrane Biological process protein transport small GTPase mediated signal transduction membrane fusion post-Golgi vesicle-mediated

Invasion (cancer) (6,024 words) [view diff] exact match in snippet view article

generated by the cortical actin cytoskeleton that is, in turn, controlled by small GTPase RhoA and its effector, ROCK kinase. This GTPase belongs to the superfamily

Rab escort protein 1 (1,240 words) [view diff] exact match in snippet view article find links to article

perception protein targeting to membrane regulation of catalytic activity small GTPase mediated signal transduction regulation of apoptotic process post-translational

RABL6 (588 words) [view diff] exact match in snippet view article find links to article

cytoplasm nucleus centrosome cytosol intracellular anatomical structure Biological process small GTPase mediated signal transduction Sources:Amigo / QuickGO

SH3BP1 (545 words) [view diff] exact match in snippet view article find links to article

establishment of epithelial cell apical/basal polarity negative regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway phagocytosis

RAB38 (450 words) [view diff] exact match in snippet view article find links to article

melanosome assembly mitochondrion organization vesicle-mediated transport small GTPase mediated signal transduction post-translational protein modification

SH2D3A (544 words) [view diff] exact match in snippet view article find links to article

Cellular component intracellular anatomical structure Biological process small GTPase mediated signal transduction JNK cascade positive regulation of signal

NET1 (541 words) [view diff] exact match in snippet view article find links to article

signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction regulation of cell growth signal transduction

Dedicator of cytokinesis protein 11 (966 words) [view diff] exact match in snippet view article find links to article

exchange factor activity Cellular component cytosol Biological process small GTPase mediated signal transduction blood coagulation B cell homeostasis marginal

ARHGEF9 (510 words) [view diff] exact match in snippet view article find links to article

process regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction G protein-coupled receptor signaling pathway

RUFY1 (505 words) [view diff] exact match in snippet view article find links to article

transport endocytosis phosphatidylinositol biosynthetic process regulation of endocytosis small GTPase mediated signal transduction Sources:Amigo / QuickGO

RABGAP1 (339 words) [view diff] exact match in snippet view article find links to article

de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (August 2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed

RAB5C (473 words) [view diff] exact match in snippet view article find links to article

degranulation transport intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

PLEKHM1 (828 words) [view diff] exact match in snippet view article find links to article

C-terminal Rubicon Homology (RH) domain, which mediates interaction with small GTPase Rab7. This domain is shared with family RH domain containing family members

RAB30 (137 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum to Golgi vesicle-mediated transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

RAPGEF6 (416 words) [view diff] exact match in snippet view article find links to article

membrane centrosome Biological process regulation of GTPase activity small GTPase mediated signal transduction positive regulation of GTPase activity Ras

ARHGAP24 (566 words) [view diff] exact match in snippet view article find links to article

positive regulation of GTPase activity cell differentiation regulation of small GTPase mediated signal transduction angiogenesis signal transduction Sources:Amigo

RAB21 (514 words) [view diff] exact match in snippet view article find links to article

Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (Jun 2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins"

Family with sequence similarity 13, member A1 (365 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction Sources:Amigo / QuickGO

Tuberous sclerosis protein (1,075 words) [view diff] exact match in snippet view article find links to article

has been shown to stimulate (down regulate) the GTPase activity of the small GTPase Rheb, which is – in its GTP bound form – an activator of mTORC1. TSC1

ARHGDIG (640 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity regulation of catalytic activity regulation of small GTPase mediated signal transduction Rho protein signal transduction regulation

MTG1 (651 words) [view diff] exact match in snippet view article find links to article

20697. PMID 9694811. Opdam FJ, Echard A, Croes HJ, et al. (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed

RAB37 (434 words) [view diff] exact match in snippet view article find links to article

regulation of exocytosis intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

RAB6C (451 words) [view diff] exact match in snippet view article find links to article

vesicle-mediated transport, Golgi to endoplasmic reticulum mitotic cell cycle small GTPase mediated signal transduction intracellular protein transport Rab protein

PTPLAD1 (580 words) [view diff] exact match in snippet view article find links to article

regulation by virus of viral protein levels in host cell lipid metabolism small GTPase mediated signal transduction fatty acid metabolic process JNK cascade

RUNDC3A (450 words) [view diff] exact match in snippet view article find links to article

binding Cellular component cytosol plasma membrane Biological process small GTPase mediated signal transduction positive regulation of guanylate cyclase

ARHGAP5 (813 words) [view diff] exact match in snippet view article find links to article

cytosol plasma membrane Biological process cell adhesion regulation of small GTPase mediated signal transduction Rho protein signal transduction signal transduction

EVI5 (463 words) [view diff] exact match in snippet view article find links to article

RH, Jackson PK, Eldridge AG (Jan 2007). "Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene". Proceedings of the National Academy

ARHGAP9 (500 words) [view diff] exact match in snippet view article find links to article

region secretory granule lumen cytoplasm Biological process regulation of small GTPase mediated signal transduction signal transduction positive regulation

DAAM1 (698 words) [view diff] exact match in snippet view article find links to article

subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity

IFT27 (135 words) [view diff] exact match in snippet view article find links to article

spermatogenesis Rab protein signal transduction cell differentiation signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

Dedicator of cytokinesis protein 3 (1,035 words) [view diff] exact match in snippet view article find links to article

factor activity Cellular component cytoplasm cytosol Biological process small GTPase mediated signal transduction positive regulation of non-membrane spanning

NRBP1 (724 words) [view diff] exact match in snippet view article find links to article

Senadheera D, Groffen J, Heisterkamp N (Apr 2002). "Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain". Int J Mol Med

MICALL1 (489 words) [view diff] exact match in snippet view article find links to article

PMID 11258795. Marzesco AM, Dunia I, Pandjaitan R, et al. (2002). "The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial

DLL4 (966 words) [view diff] exact match in snippet view article find links to article

(September 2007). "Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras". The Journal of Biological Chemistry. 282 (39): 28991–9001. doi:10

PREX1 (775 words) [view diff] exact match in snippet view article find links to article

TOR signaling positive regulation of apoptotic process regulation of small GTPase mediated signal transduction G protein-coupled receptor signaling pathway

Alpha-2-Macroglobulin (1,631 words) [view diff] exact match in snippet view article find links to article

negative regulation of complement activation, lectin pathway regulation of small GTPase mediated signal transduction positive regulation of GTPase activity negative

Dedicator of cytokinesis protein 8 (1,260 words) [view diff] exact match in snippet view article find links to article

structure Biological process negative regulation of T cell apoptotic process small GTPase mediated signal transduction immunological synapse formation blood coagulation

SIPA1L1 (545 words) [view diff] exact match in snippet view article find links to article

regulation of dendrite morphogenesis regulation of axonogenesis regulation of small GTPase mediated signal transduction regulation of dendritic spine morphogenesis

NRBP1 (724 words) [view diff] exact match in snippet view article find links to article

Senadheera D, Groffen J, Heisterkamp N (Apr 2002). "Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain". Int J Mol Med

RASGEF1A (368 words) [view diff] exact match in snippet view article find links to article

process positive regulation of Ras protein signal transduction cell migration MAPK cascade small GTPase mediated signal transduction Sources:Amigo / QuickGO

ARHGAP26 (995 words) [view diff] exact match in snippet view article find links to article

cytoskeleton focal adhesion cellular component Biological process regulation of small GTPase mediated signal transduction actin cytoskeleton organization nervous

ADCYAP1R1 (1,555 words) [view diff] exact match in snippet view article find links to article

ethanol cAMP-mediated signaling signal transduction positive regulation of small GTPase mediated signal transduction G protein-coupled receptor signaling pathway

ARHGAP29 (525 words) [view diff] exact match in snippet view article find links to article

process Rho protein signal transduction signal transduction regulation of small GTPase mediated signal transduction intracellular signal transduction positive

ABCA1 (2,082 words) [view diff] exact match in snippet view article find links to article

transporter activity phospholipid transporter activity cholesterol binding small GTPase binding protein binding syntaxin binding signaling receptor binding phospholipid

RAB8A (1,100 words) [view diff] exact match in snippet view article find links to article

Pimplikar S, Parton RG, Virta H, Zerial M, Simons K (Oct 1993). "Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma

ARHGAP8 (558 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm cytosol Biological process regulation of small GTPase mediated signal transduction signal transduction positive regulation

RAB13 (640 words) [view diff] exact match in snippet view article find links to article

(1998). "The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes". J. Biol. Chem. 273 (35): 22340–5. doi:10.1074/jbc

RasGEF domain family member 1C (75 words) [view diff] exact match in snippet view article find links to article

factor activity Cellular component intracellular anatomical structure Biological process small GTPase mediated signal transduction Sources:Amigo / QuickGO

RAP1GAP2 (431 words) [view diff] exact match in snippet view article find links to article

of GTPase activity negative regulation of neuron projection development regulation of small GTPase mediated signal transduction Sources:Amigo / QuickGO

RAPGEF5 (532 words) [view diff] exact match in snippet view article find links to article

Cellular component nucleus nucleoplasm nuclear body Biological process small GTPase mediated signal transduction nervous system development Sources:Amigo

ARHGEF5 (554 words) [view diff] exact match in snippet view article find links to article

fiber assembly positive regulation of apoptotic process regulation of small GTPase mediated signal transduction G protein-coupled receptor signaling pathway

Dedicator of cytokinesis protein 9 (1,047 words) [view diff] exact match in snippet view article find links to article

cytosol endomembrane system membrane Biological process blood coagulation small GTPase mediated signal transduction positive regulation of GTPase activity biological

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway small GTPase mediated signal transduction protein phosphorylation cell surface receptor

Dedicator of cytokinesis protein 4 (1,495 words) [view diff] exact match in snippet view article find links to article

plasma membrane intracellular anatomical structure Biological process small GTPase mediated signal transduction cell chemotaxis negative regulation of vascular

STARD13 (718 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity endothelial tube lumen extension regulation of small GTPase mediated signal transduction endothelial cell migration signal transduction

BCAR3 (943 words) [view diff] exact match in snippet view article find links to article

Cellular component intracellular anatomical structure Biological process small GTPase mediated signal transduction lens morphogenesis in camera-type eye signal

WASF1 (1,021 words) [view diff] exact match in snippet view article find links to article

(WASP) family, plays a critical role downstream of Rac, a Rho-family small GTPase, through its involvement in the WAVE regulatory complex in regulating

Obscurin (2,500 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation protein localization to M-band regulation of small GTPase mediated signal transduction cell differentiation phosphorylation G protein-coupled

ROBO1 (1,234 words) [view diff] exact match in snippet view article find links to article

transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10

Cinnamoyl-CoA reductase (2,340 words) [view diff] exact match in snippet view article find links to article

example, evidence suggests that the CCR1 homolog is an effector of Rac1, a small GTPase important for plant defense response. In this case, the Rac1 protein

RASGRF1 (187 words) [view diff] exact match in snippet view article find links to article

activity activation of GTPase activity cell population proliferation small GTPase mediated signal transduction positive regulation of Ras protein signal

INPP5B (627 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol dephosphorylation spermatogenesis regulation of small GTPase mediated signal transduction signal transduction positive regulation

RGS19 (1,562 words) [view diff] exact match in snippet view article find links to article

membrane Biological process G protein-coupled receptor signaling pathway small GTPase mediated signal transduction autophagy negative regulation of signal

Dedicator of cytokinesis protein 7 (1,196 words) [view diff] exact match in snippet view article find links to article

establishment of neuroblast polarity axonogenesis activation of GTPase activity small GTPase mediated signal transduction interkinetic nuclear migration nervous system

Chimerin 2 (1,024 words) [view diff] exact match in snippet view article find links to article

membrane Biological process intracellular signal transduction regulation of small GTPase mediated signal transduction signal transduction positive regulation

Intraflagellar transport (2,108 words) [view diff] exact match in snippet view article find links to article

Xiong, Y., Kong, S., Sun, Z., Alkuraya, F. S. (2014). "IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with

ECT2 (1,051 words) [view diff] exact match in snippet view article find links to article

regulation of attachment of spindle microtubules to kinetochore regulation of small GTPase mediated signal transduction protein homooligomerization activation of

RAB22A (736 words) [view diff] exact match in snippet view article find links to article

Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002). "The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking"

RAB34 (568 words) [view diff] exact match in snippet view article find links to article

Sun P, Yamamoto H, Suetsugu S, Miki H, Takenawa T, Endo T (Feb 2003). "Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and

ARFRP1 (733 words) [view diff] exact match in snippet view article find links to article

to Golgi apparatus intracellular protein transport protein localization to organelle small GTPase mediated signal transduction Sources:Amigo / QuickGO

RAPGEF2 (867 words) [view diff] exact match in snippet view article find links to article

regulation of cell population proliferation Rap protein signal transduction small GTPase mediated signal transduction negative regulation of cell population proliferation

RGL2 (757 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure cellular component Biological process small GTPase mediated signal transduction Ras protein signal transduction signal transduction

ARL2 (1,206 words) [view diff] exact match in snippet view article find links to article

Antoshechkin I, Han M (2002). "The C. elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis"

PEX5 (1,507 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein C-terminus binding small GTPase binding protein N-terminus binding peroxisome targeting sequence binding enzyme

ARL3 (850 words) [view diff] exact match in snippet view article find links to article

Biological process cilium assembly kidney development intraciliary transport small GTPase mediated signal transduction photoreceptor cell development post-Golgi

RRAGC (495 words) [view diff] exact match in snippet view article find links to article

Gtr1-Gtr2 GTPase complex Biological process regulation of TOR signaling small GTPase mediated signal transduction cellular response to amino acid starvation

ARFIP2 (673 words) [view diff] exact match in snippet view article find links to article

membrane ruffle cytosol cytoplasm Biological process ruffle organization small GTPase mediated signal transduction actin cytoskeleton organization regulation

Spindle apparatus (3,300 words) [view diff] exact match in snippet view article find links to article

cross-linking motor proteins. The guanine nucleotide exchange factor for the small GTPase Ran (Regulator of chromosome condensation 1 or RCC1) is attached to nucleosomes

RAB5B (815 words) [view diff] exact match in snippet view article find links to article

protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5". J. Biol. Chem. 277 (5): 3412–8. doi:10.1074/jbc.M106276200. PMID 11733506

PAK2 (2,164 words) [view diff] exact match in snippet view article find links to article

protein binding ATP binding protein kinase binding cadherin binding small GTPase binding Cellular component membrane plasma membrane perinuclear region

CENTD1 (493 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction Sources:Amigo / QuickGO

STARD8 (816 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction Sources:Amigo / QuickGO

Spindle apparatus (3,300 words) [view diff] exact match in snippet view article find links to article

cross-linking motor proteins. The guanine nucleotide exchange factor for the small GTPase Ran (Regulator of chromosome condensation 1 or RCC1) is attached to nucleosomes

CDON (1,111 words) [view diff] exact match in snippet view article find links to article

process regulation of neuron differentiation positive regulation of small GTPase mediated signal transduction positive regulation of protein phosphorylation

SH2D3C (976 words) [view diff] exact match in snippet view article find links to article

factor activity Cellular component cytoplasm membrane Biological process small GTPase mediated signal transduction JNK cascade positive regulation of signal

SLIT2 (999 words) [view diff] exact match in snippet view article find links to article

negative regulation of actin filament polymerization negative regulation of small GTPase mediated signal transduction negative regulation of retinal ganglion

DNAJA3 (1,956 words) [view diff] exact match in snippet view article find links to article

response to interferon-gamma negative regulation of protein kinase activity small GTPase mediated signal transduction protein stabilization mitochondrion organization

CYFIP1 (921 words) [view diff] exact match in snippet view article find links to article

(specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase". J. Biol. Chem. 273 (1): 291–5. doi:10.1074/jbc.273.1.291. PMID 9417078

RASGRP3 (1,031 words) [view diff] exact match in snippet view article find links to article

process intracellular signal transduction regulation of GTPase activity small GTPase mediated signal transduction MAPK cascade positive regulation of GTPase

Signal recognition particle receptor (829 words) [view diff] exact match in snippet view article find links to article

side and helices alpha2-alpha4 on the other. They interact with the small GTPase SR-beta, forming a complex that matches a class of small G protein-effector

CENTD2 (625 words) [view diff] exact match in snippet view article find links to article

cell shape negative regulation of stress fiber assembly regulation of small GTPase mediated signal transduction positive regulation of filopodium assembly

ARHGAP4 (782 words) [view diff] exact match in snippet view article find links to article

cytoskeleton organization Rho protein signal transduction regulation of small GTPase mediated signal transduction negative regulation of axon extension signal

NCKAP1 (1,034 words) [view diff] exact match in snippet view article find links to article

(specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase". The Journal of Biological Chemistry. 273 (1): 291–5. doi:10.1074/jbc

CD2AP (1,288 words) [view diff] exact match in snippet view article find links to article

localization to nucleus actin filament organization negative regulation of small GTPase mediated signal transduction cell-cell adhesion protein-containing complex

ERRFI1 (932 words) [view diff] exact match in snippet view article find links to article

domain binding kinase binding protein binding protein kinase binding small GTPase binding Cellular component membrane extrinsic component of cytoplasmic

TRIP10 (1,158 words) [view diff] exact match in snippet view article find links to article

exosome Biological process endocytosis cell communication regulation of small GTPase mediated signal transduction signal transduction positive regulation

CUL1 (1,072 words) [view diff] exact match in snippet view article find links to article

PMID 11359933. Senadheera D, Haataja L, Groffen J, Heisterkamp N (2001). "The small GTPase Rac interacts with ubiquitination complex proteins Cullin-1 and CDC23"

Cytokinesis (3,533 words) [view diff] exact match in snippet view article find links to article

the division plane by promoting concentration and activation of the small GTPase RhoA at the equatorial cortex. A third hypothesis is the astral relaxation

Dedicator of cytokinesis protein 2 (1,587 words) [view diff] exact match in snippet view article find links to article

granule lumen Biological process positive regulation of phagocytosis small GTPase mediated signal transduction alpha-beta T cell activation mitigation

RAB2A (994 words) [view diff] exact match in snippet view article find links to article

modification transport intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

ARHGAP11B (688 words) [view diff] exact match in snippet view article find links to article

activity Cellular component cytosol Biological process regulation of small GTPase mediated signal transduction signal transduction cerebral cortex development

IQGAP1 (3,922 words) [view diff] exact match in snippet view article find links to article

1091/mbc.3.5.475. PMC 275601. PMID 1611153. Narumiya S (August 1996). "The small GTPase Rho: cellular functions and signal transduction". J. Biochem. 120 (2):

RIT2 (734 words) [view diff] exact match in snippet view article find links to article

transcription by RNA polymerase II regulation of calcium-mediated signaling small GTPase mediated signal transduction adenylate cyclase-activating G protein-coupled

GARNL1 (506 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm nucleus Biological process regulation of small GTPase mediated signal transduction activation of GTPase activity positive regulation

Retinitis pigmentosa GTPase regulator (2,273 words) [view diff] exact match in snippet view article find links to article

been shown to preferentially interact with the GDP-bound form of the small GTPase RAB8A. RAB8A is involved in rhodopsin trafficking in primary cilia. The

RHOT2 (1,180 words) [view diff] exact match in snippet view article find links to article

homeostasis mitochondrion transport along microtubule regulation of small GTPase mediated signal transduction mitochondrial outer membrane permeabilization

TRAPP complex (979 words) [view diff] exact match in snippet view article find links to article

proteins starts with a protein called Sec12. This protein recruits a small GTPase called Sar1. Sar1 can be thought of as a switch which is active when

RAP2B (818 words) [view diff] exact match in snippet view article find links to article

Greco F, Sinigaglia F, Balduini C, Torti M (2005). "Activation of the small GTPase Rap2B in agonist-stimulated human platelets". J. Thromb. Haemost. 2 (12):

TBC1D24 (467 words) [view diff] exact match in snippet view article find links to article

PMID 10574461. Fukuda M (June 2011). "TBC proteins: GAPs for mammalian small GTPase Rab?". Bioscience Reports. 31 (3): 159–68. doi:10.1042/BSR20100112. PMID 21250943

Nematocida parisii (656 words) [view diff] exact match in snippet view article find links to article

John J.; Smelkinson, Margery G.; Troemel, Emily R. (2014-06-03). "The small GTPase RAB-11 directs polarized exocytosis of the intracellular pathogen N.

PLD2 (1,734 words) [view diff] exact match in snippet view article find links to article

signaling pathway involved in phagocytosis lipid metabolism cell motility small GTPase mediated signal transduction lipid catabolic process synaptic vesicle

USO1 (1,111 words) [view diff] exact match in snippet view article find links to article

protein transport vesicle-mediated transport Golgi organization transport small GTPase mediated signal transduction secretory granule localization regulation

RASGRP2 (682 words) [view diff] exact match in snippet view article find links to article

process cellular response to calcium ion intracellular signal transduction small GTPase mediated signal transduction positive regulation of GTPase activity regulation

Oncogene (3,182 words) [view diff] exact match in snippet view article find links to article

(constitutively), even without signals from outside the cell. Ras is a small GTPase that hydrolyses GTP into GDP and phosphate. Ras is activated by growth

ARF5 (1,027 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure membrane Biological process protein transport small GTPase mediated signal transduction vesicle-mediated transport retrograde vesicle-mediated

SIAH2 (1,158 words) [view diff] exact match in snippet view article find links to article

of cysteine-type endopeptidase activity involved in apoptotic process small GTPase mediated signal transduction regulation of protein ubiquitination negative

Alan Hall (1,975 words) [view diff] exact match in snippet view article find links to article

providing specificity. In the same year, Hall investigated the role of the small GTPase Ral in neurite branching. After microinjection of cortical and sympathetic

Meristem (4,541 words) [view diff] exact match in snippet view article find links to article

example, the CLV complex has been found to be associated with Rho/Rac small GTPase-related proteins. These proteins may act as an intermediate between the

PDE6D (1,053 words) [view diff] exact match in snippet view article find links to article

1998). "The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes". The Journal of Biological Chemistry. 273 (35):

Guanosine pentaphosphate (1,958 words) [view diff] exact match in snippet view article find links to article

inhibitor. ppGpp can bind with Obg protein which belongs to the conserved, small GTPase protein family. Obg protein interacts with several regulators (RsbT,

Michael Fischbach (965 words) [view diff] exact match in snippet view article find links to article

Hospital Cancer Center on the biochemistry of oncogenic mutants of the small GTPase Ras. In 2007, he earned his Ph.D. in Chemistry and Chemical Biology from

CENTD3 (539 words) [view diff] exact match in snippet view article find links to article

protein signal transduction cytoskeleton organization regulation of small GTPase mediated signal transduction vesicle-mediated transport signal transduction

RAB4B (1,093 words) [view diff] exact match in snippet view article find links to article

Grémeaux T, Bonnafous S, Gugenheim J, et al. (April 2009). "Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization

ARF1 (1,380 words) [view diff] exact match in snippet view article find links to article

exocytosis regulation of receptor internalization synaptic vesicle budding small GTPase mediated signal transduction cellular copper ion homeostasis long-term

EXOC2 (916 words) [view diff] exact match in snippet view article find links to article

K, Asano S, Tanaka K, et al. (2002). "The exocyst complex binds the small GTPase RalA to mediate filopodia formation". Nat. Cell Biol. 4 (1): 73–8. doi:10

GOPC (1,213 words) [view diff] exact match in snippet view article find links to article

transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10". J. Biol. Chem. 280 (5): 3731–9. doi:10.1074/jbc.M410026200. PMID 15546864

ARHGEF2 (1,134 words) [view diff] exact match in snippet view article find links to article

intracellular protein transport innate immune response regulation of small GTPase mediated signal transduction positive regulation of transcription by

Calcineurin B homologous protein 1 (929 words) [view diff] exact match in snippet view article find links to article

sodium:proton antiporter activity negative regulation of phosphatase activity small GTPase mediated signal transduction protein stabilization cellular response

Kalirin (3,328 words) [view diff] exact match in snippet view article find links to article

process regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction vesicle-mediated transport signal transduction

PIK3R2 (1,401 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol 3-kinase signaling T cell receptor signaling pathway regulation of small GTPase mediated signal transduction phosphatidylinositol-mediated signaling

RALGDS (1,574 words) [view diff] exact match in snippet view article find links to article

component cytosol brush border cytoplasm nucleus Biological process small GTPase mediated signal transduction Ras protein signal transduction signal transduction

Lewis C. Cantley (3,257 words) [view diff] exact match in snippet view article find links to article

required for activation of mTOR TORC1 kinase activity via regulation of the small GTPase rheb. The Cantley lab also was one of a few labs that nearly simultaneously

PIK3R2 (1,401 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol 3-kinase signaling T cell receptor signaling pathway regulation of small GTPase mediated signal transduction phosphatidylinositol-mediated signaling

Kalirin (3,328 words) [view diff] exact match in snippet view article find links to article

process regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction vesicle-mediated transport signal transduction

T-cell lymphoma invasion and metastasis-inducing protein 1 (1,315 words) [view diff] exact match in snippet view article find links to article

transduction regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction cell migration positive regulation of dendritic

OPHN1 (1,188 words) [view diff] exact match in snippet view article find links to article

process regulation of synaptic transmission, glutamatergic regulation of small GTPase mediated signal transduction actin cytoskeleton organization signal transduction

Lewis C. Cantley (3,257 words) [view diff] exact match in snippet view article find links to article

required for activation of mTOR TORC1 kinase activity via regulation of the small GTPase rheb. The Cantley lab also was one of a few labs that nearly simultaneously

RASGRP1 (1,140 words) [view diff] exact match in snippet view article find links to article

positive regulation of natural killer cell mediated cytotoxicity signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

GOLGA4 (1,021 words) [view diff] exact match in snippet view article find links to article

(2004). "Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1". Nat. Struct. Mol. Biol. 11 (1): 86–94. doi:10.1038/nsmb714. PMID 14718928

Phospholipase D1 (2,140 words) [view diff] exact match in snippet view article find links to article

process regulation of microvillus assembly lipid metabolism cell motility small GTPase mediated signal transduction lipid catabolic process chemotaxis Ras protein

ARHGDIA (1,302 words) [view diff] exact match in snippet view article find links to article

axonogenesis regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway regulation

DAB1 (1,845 words) [view diff] exact match in snippet view article find links to article

cell differentiation negative regulation of astrocyte differentiation small GTPase mediated signal transduction dendrite development neuron migration lateral

RHOT1 (1,262 words) [view diff] exact match in snippet view article find links to article

outer membrane Biological process cellular homeostasis regulation of small GTPase mediated signal transduction mitochondrial outer membrane permeabilization

Pseudoenzyme (1,384 words) [view diff] exact match in snippet view article find links to article

conformations, but is essential for nucleating the CENP-I, CENP-H, CENP-K small GTPase complex to regulate kinetochore assembly Regulation of protein localisation

YWHAQ (1,999 words) [view diff] exact match in snippet view article find links to article

signaling pathway membrane organization negative regulation of transcription, DNA-templated small GTPase mediated signal transduction Sources:Amigo / QuickGO

Myotonin-protein kinase (2,426 words) [view diff] exact match in snippet view article find links to article

activation of DMPK-1 and -2 may be mediated by transitory interaction with a small GTPase (G). A general model that accounts for DMPK oligomerization, processing

PLCE1 (1,740 words) [view diff] exact match in snippet view article find links to article

metabolism positive regulation of cytosolic calcium ion concentration small GTPase mediated signal transduction regulation of Ras protein signal transduction

Proto-oncogene tyrosine-protein kinase Src (2,795 words) [view diff] exact match in snippet view article find links to article

phosphorylation neurotrophin TRK receptor signaling pathway positive regulation of small GTPase mediated signal transduction bone resorption central nervous system development

T-cell receptor (5,385 words) [view diff] exact match in snippet view article find links to article

nucleotide exchange factor (GEF), to the membrane. RasGRP activates the small GTPase Ras by exchanging Guanosine diphosphate (GDP) bound to Ras against Guanosine

TBC domain (1,127 words) [view diff] exact match in snippet view article find links to article

PMC 3655817. PMID 23485563. Fukuda M (2011). "TBC proteins: GAPs for mammalian small GTPase Rab?". Bioscience Reports. 31 (3): 159–68. doi:10.1042/BSR20100112. PMID 21250943

Xenopus (5,801 words) [view diff] exact match in snippet view article find links to article

been critical to diverse studies of cell division. For example, the small GTPase Ran was first found to regulate interphase nuclear transport, but Xenopus

KRIT1 (1,398 words) [view diff] exact match in snippet view article find links to article

of establishment of cell polarity negative regulation of angiogenesis small GTPase mediated signal transduction angiogenesis negative regulation of endothelial

RAB18 (1,270 words) [view diff] exact match in snippet view article find links to article

brain development lipid droplet organization neutrophil degranulation small GTPase mediated signal transduction import into nucleus intracellular protein

Dendritic spine (5,682 words) [view diff] exact match in snippet view article find links to article

1159/000134729. PMID 9605859. Scott EK, Reuter JE, Luo L (April 2003). "Small GTPase Cdc42 is required for multiple aspects of dendritic morphogenesis". The

Rho gtpase activating protein 21 (710 words) [view diff] exact match in snippet view article find links to article

Golgi location signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction Sources:Amigo / QuickGO

BRAF (gene) (5,394 words) [view diff] exact match in snippet view article

ion binding kinase activity protein serine/threonine kinase activity small GTPase binding protein binding identical protein binding ATP binding MAP kinase

Angiomotin (2,235 words) [view diff] exact match in snippet view article find links to article

gastrulation positive regulation of embryonic development regulation of small GTPase mediated signal transduction positive regulation of stress fiber assembly

Schizosaccharomyces pombe (6,047 words) [view diff] exact match in snippet view article find links to article

kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42". Current Biology. 19 (15): 1314–9. doi:10.1016/j.cub.2009.06.057

Cingulin (2,075 words) [view diff] exact match in snippet view article find links to article

"Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA". Molecular Biology of the Cell. 17 (8): 3569–77. doi:10.1091/mbc

Actin assembly-inducing protein (2,132 words) [view diff] exact match in snippet view article find links to article

such as endocytosis and cell motility. Activated by Cdc42, a Rho-family small GTPase, WASP/N-WASP activates the Arp2/3 complex, which leads to rapid actin

Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article

JF, Yang Y, Yoo JS, Lee JD (January 2003). "ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2

CRKL (3,165 words) [view diff] exact match in snippet view article find links to article

"Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL"

DIRAS3 (gene) (1,750 words) [view diff] exact match in snippet view article

regulation of cyclin-dependent protein serine/threonine kinase activity signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO

T-cell activation RhoGTPase activating protein (831 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction Sources:Amigo / QuickGO

RASD1 (2,332 words) [view diff] exact match in snippet view article find links to article

allows glucocorticoids to induce expression of RASD1. This protein is a small GTPase belonging to the Ras superfamily. As a Ras superfamily member, RASD1

Syndecan-4 (2,088 words) [view diff] exact match in snippet view article find links to article

results in a decrease of invasive growth, and reduced expression of the small GTPase Rac1, Activating transcription factor 2 (ATF2), and MMP3. Syndecan-4

MTOR inhibitors (6,225 words) [view diff] exact match in snippet view article find links to article

phosphorylates PKCα, AKT and paxillin, and regulates the activity of the small GTPase, Rac, and Rho related to cell survival, migration and regulation of the

PSMC1 (3,857 words) [view diff] exact match in snippet view article find links to article

proteasome-inhibited megakaryocytes was due to upregulation and hyperactivation of the small GTPase, RhoA. It appears that proteasome function, through an underlying mechanisms

ARHGDIB (2,405 words) [view diff] exact match in snippet view article find links to article

redox state regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction regulation of catalytic activity Rho protein

C-Raf (8,674 words) [view diff] exact match in snippet view article find links to article

nucleotide binding metal ion binding protein serine/threonine kinase activity small GTPase binding protein binding identical protein binding ATP binding kinase

Madin-Darby canine kidney cells (2,658 words) [view diff] exact match in snippet view article find links to article

beyond the requirement for a signaling protein involved in regulating the small GTPase Rho. Moreover, the Gardel lab has shown that invasive motility of MDCK

Mir-449 microRNA precursor family (1,307 words) [view diff] exact match in snippet view article find links to article

control apical actin network formation during multiciliogenesis through small GTPase pathways"". Nature Communications. 18 (6): 8386. Bibcode:2015NatCo..

MDia1 (1,955 words) [view diff] exact match in snippet view article find links to article

mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin". EMBO J. 16 (11): 3044–56. doi:10.1093/emboj/16

Edgar Pick (1,878 words) [view diff] exact match in snippet view article find links to article

is best known for the finding (with A. Abo and A.W. Segal) that the small GTPase Rac is an essential participant in the activation of the NADPH oxidase

Eric J. Nestler (3,748 words) [view diff] exact match in snippet view article find links to article

Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling". Neuron. 89 (3): 566–582. doi:10.1016/j.neuron.2016.01.031

Halperin-Birk syndrome (1,457 words) [view diff] exact match in snippet view article find links to article

hierarchically, driven by the initial recruitment and activation of the small GTPase SAR1, which exists in a soluble cytoplasmic form when in its GDP-bound

Synaptic stabilization (2,927 words) [view diff] exact match in snippet view article find links to article

factor (GEF), ephexin1. Phosphorylated ephexin1 can then activate the small GTPase, RhoA, leading to subsequent activation of its effector, Rho-kinase (ROCK)

Cingulin-like protein 1 (2,104 words) [view diff] exact match in snippet view article find links to article

tight junction Biological process actin filament organization negative regulation of small GTPase mediated signal transduction Sources:Amigo / QuickGO

EVI5L (1,684 words) [view diff] exact match in snippet view article find links to article

PMC 3555715. Fukuda M (June 2011). "TBC proteins: GAPs for mammalian small GTPase Rab?". Bioscience Reports. 31 (3): 159–68. doi:10.1042/BSR20100112. PMID 21250943

RAPGEF3 (3,461 words) [view diff] exact match in snippet view article find links to article

reorganization intracellular signal transduction regulation of insulin secretion small GTPase mediated signal transduction Rap protein signal transduction positive

DLC1 (3,165 words) [view diff] exact match in snippet view article find links to article

cysteine-type endopeptidase activity involved in apoptotic process regulation of small GTPase mediated signal transduction negative regulation of focal adhesion assembly

FAM13B (842 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction Sources:Amigo / QuickGO

Prescient Therapeutics (2,313 words) [view diff] exact match in snippet view article find links to article

transferase-1(GGT-1). This enzyme, by posttranslationally modifying the small GTPase Rho with isoprenoid lipids, plays a role in malignant transformation

Lymphangioleiomyomatosis (11,094 words) [view diff] exact match in snippet view article find links to article

(mTOR) signaling complex by directly controlling the activity of the small GTPase Rheb via the GTPase activating protein (GAP) domain of TSC2. Rheb binds

Jean Gruenberg (2,708 words) [view diff] exact match in snippet view article find links to article

Jean (2002-03-15). "Late endosome motility depends on lipids via the small GTPase Rab7". The EMBO Journal. 21 (6): 1289–1300. doi:10.1093/emboj/21.6.1289

Endoplasmic reticulum membrane protein complex (3,054 words) [view diff] exact match in snippet view article find links to article

transfer of phosphatidylserine (PS) from the ER. EMC6 interacts with the small GTPase RAB5A and Beclin-1, regulators of autophagosome formation. This observation

Reelin (15,715 words) [view diff] exact match in snippet view article find links to article

positive regulation of neuron projection development positive regulation of small GTPase mediated signal transduction positive regulation of synaptic transmission

Slit-Robo (4,218 words) [view diff] exact match in snippet view article find links to article

transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10

Folliculin (5,618 words) [view diff] exact match in snippet view article find links to article

translocation of mTORC1 to the lysosomal surface for activation by the small GTPase Ras-homolog enriched in brain (Rheb). GTP-loading of RagA/B is a requirement

Juan Carlos Lacal (1,539 words) [view diff] exact match in snippet view article find links to article

carcinogenesis, and highlighted the critical role of several members of the small GTPase superfamily in addition to Ras and Rho A, in controlling key cellular

Clathrin-independent endocytosis (2,003 words) [view diff] exact match in snippet view article find links to article

destiny and budding as it relates to the Cavin 1 protein. RhoA is a small GTPase mechanism that aids in the correct sorting of the beta chain of the

Epigenetics of neurodegenerative diseases (13,392 words) [view diff] exact match in snippet view article find links to article

sporadic cases. C9orf72 likely functions as a guanine exchange factor for a small GTPase, but this is likely not related to the underlying cause of ALS. The hexanucleotide