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searching for SKP2 22 found (39 total)

alternate case: sKP2

SCF complex (2,021 words) [view diff] case mismatch in snippet view article find links to article

aggregating to target proteins independently of the complex. Each FBP (e.g. Skp2) may recognize several different substrates in a manner that is dependent

F-box protein (735 words) [view diff] case mismatch in snippet view article find links to article

in few positions. It was first identified in cyclin F. The F-box motif of Skp2, consisting of three alpha-helices, interacts directly with the SCF protein

CDC34 (1,341 words) [view diff] exact match in snippet view article find links to article

Lorca T, et al. (December 2001). "Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome". Molecular

Leucine-rich repeat (1,070 words) [view diff] case mismatch in snippet view article find links to article

PMC 2645405. PMID 18986514. Eukaryotic Linear Motif resource motif class LIG_SCF_Skp2-Cks1_1 SCOP LRR fold CATH Alpha-beta horseshoe architecture LRRML: a conformational

Cyclin-dependent kinase 9 (1,460 words) [view diff] exact match in snippet view article find links to article

Ki K, Benkirane M (December 2001). "Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome". Mol

Androgen deprivation-induced senescence (310 words) [view diff] case mismatch in snippet view article find links to article

depletion induces senescence in prostate cancer cells through down-regulation of Skp2". Neoplasia. 13 (6): 526–36. doi:10.1593/neo.11182. PMC 3114246. PMID 21677876

DIAPH1 (1,260 words) [view diff] case mismatch in snippet view article find links to article

2004). "Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition". The Journal of Biological Chemistry

FOXP3 (3,448 words) [view diff] case mismatch in snippet view article find links to article

factor in cancer development. First, Foxp3 represses expression of HER2, Skp2, SATB1 and MYC oncogenes and induces expression of tumour suppressor genes

FZR1 (996 words) [view diff] case mismatch in snippet view article find links to article

Kirschner MW, Kaelin WG (March 2004). "Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex". Nature. 428 (6979):

Cyclin T1 (1,358 words) [view diff] exact match in snippet view article find links to article

Ki K, Benkirane M (December 2001). "Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome". Mol

Proteasome (12,663 words) [view diff] case mismatch in snippet view article find links to article

itself is regulated by the APC via ubiquitination of the adaptor protein, Skp2, which prevents SCF activity before the G1-S transition. Individual components

Zoi Lygerou (608 words) [view diff] case mismatch in snippet view article find links to article

license DNA for replication in fission yeast Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis Accurate Processing of a

NEDD8 (2,832 words) [view diff] case mismatch in snippet view article find links to article

of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1)". Biochemical and Biophysical Research Communications.

DREAM complex (3,065 words) [view diff] case mismatch in snippet view article find links to article

phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2)". Genes & Development. 16 (22): 2946–57. doi:10.1101/gad.1011202. PMC 187481

Michele Pagano (biochemist) (783 words) [view diff] exact match in snippet view article

Pagano, Michele (June 2008). "Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer". Nature Reviews. Cancer. 8 (6):

YWHAZ (3,619 words) [view diff] exact match in snippet view article find links to article

induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells". Cell Death & Disease. 5 (11): e1537. doi:10.1038/cddis

CUL3 (2,387 words) [view diff] exact match in snippet view article find links to article

cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A". Cell Growth & Differentiation. 9 (6): 435–49. PMID 9663463

APC/C activator protein CDH1 (1,551 words) [view diff] case mismatch in snippet view article find links to article

APCCdh1 target proteins, such as cyclin A and B, the kinase AuroraB, PLK1, Skp2 and Cdc20, another APC/c co- activator. The main function of Cdh1 is to suppress

FBXL2 (950 words) [view diff] case mismatch in snippet view article find links to article

Glaise D, Guguen-Guillouzo C (October 1999). "Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats". FEBS Letters

BTRC (gene) (3,356 words) [view diff] exact match in snippet view article

D, Pagano M (June 2008). "Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer". Nature Reviews. Cancer. 8 (6):

CUL4B (2,948 words) [view diff] case mismatch in snippet view article find links to article

Fujita M, Lygerou Z, Nishimoto T (Mar 2006). "Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis". The EMBO Journal. 25 (5):

FBXW11 (3,045 words) [view diff] exact match in snippet view article find links to article

Frescas D, Pagano M (Jun 2008). "Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer". Nature Reviews. Cancer. 8 (6):