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Longer titles found: Pleckstrin homology domain containing A4 (view), Pleckstrin homology domain containing S1 (view)

searching for Pleckstrin homology domain 83 found (127 total)

alternate case: pleckstrin homology domain

PLEKHA5 (595 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family A member 5 is a protein that in humans is encoded by the PLEKHA5 gene. GRCh38: Ensembl release 89: ENSG00000052126

PLEKHA6 (419 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family A member 6 is a protein that in humans is encoded by the PLEKHA6 gene. GRCh38: Ensembl release 89: ENSG00000143850

PLEKHO1 (918 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene. PLEKHO1 has been shown to interact

PLEKHA1 (503 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family A member 1 is a protein that in humans is encoded by the PLEKHA1 gene. PLEKHA1 has been shown to interact

PLEKHB2 (460 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family B member 2 is a protein that in humans is encoded by the PLEKHB2 gene. GRCh38: Ensembl release 89: ENSG00000115762

DNM1 (1,488 words) [view diff] exact match in snippet view article find links to article

D, Salim K, Gout I, et al. (1995). "Crystal structure of the pleckstrin homology domain from dynamin". Nat. Struct. Biol. 1 (11): 782–8. doi:10.1038/nsb1194-782

PLEKHM2 (271 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family M member 2 is a protein that in humans is encoded by the PLEKHM2 gene. GRCh38: Ensembl release 89: ENSG00000116786

DGKQ (575 words) [view diff] exact match in snippet view article find links to article

contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in

PLEKHF2 (448 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family F member 2 is a protein that in humans is encoded by the PLEKHF2 gene. GRCh38: Ensembl release 89: ENSG00000175895

PLEKHA8 (407 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain containing A8 is a protein that in humans is encoded by the PLEKHA8 gene. GRCh38: Ensembl release 89: ENSG00000106086 – Ensembl

PLEKHM1 (828 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain-containing family M member 1 also known as PLEKHM1 is a protein that in humans is encoded by the PLEKHM1 gene. PLEKHM1 may have

PLEKHG5 (380 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain containing, family G member 5 (PLEKHG5) is a protein that in humans is encoded by the PLEKHG5 gene. Eight transcript variants

FERMT2 (901 words) [view diff] exact match in snippet view article find links to article

Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans

CYTH3 (728 words) [view diff] exact match in snippet view article find links to article

requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain". Biochem. J. 335 ( Pt 1) (Pt 1): 139–46. doi:10.1042/bj3350139

DAPP1 (707 words) [view diff] no match in snippet view article find links to article

S, Currie RA, Campbell DG, et al. (2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities"

PLEKHG2 (1,151 words) [view diff] exact match in snippet view article find links to article

Pleckstrin homology domain containing, family G member 2 (PLEKHG2) is a protein that in humans is encoded by the PLEKHG2 gene. It is sometimes written

Diacylglycerol kinase (505 words) [view diff] exact match in snippet view article find links to article

a recoverin homology domain Type 2 - DGK-δ, DGK-η - contain a pleckstrin homology domain Type 3 - DGK-ε - has specificity for arachidonate-containing DAG

DGKD (621 words) [view diff] exact match in snippet view article find links to article

"Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine

Kalirin (3,328 words) [view diff] exact match in snippet view article find links to article

protein duo (DUO), or serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, is a protein that in humans is encoded by the KALRN gene. Kalirin

Oxysterol-binding protein (2,071 words) [view diff] no match in snippet view article find links to article

The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs). Concretely, they constitute a family of sterol

BMX (gene) (1,196 words) [view diff] no match in snippet view article

Pretlow TG, Kung HJ (1998). "Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3′-kinase and is involved

MPDZ (1,136 words) [view diff] no match in snippet view article find links to article

Lucocq JM, Alessi DR (February 2002). "Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the

PLCD1 (904 words) [view diff] exact match in snippet view article find links to article

Shimohama S, Kamiya S, Fujii M, et al. (1998). "Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss

CYTH2 (1,129 words) [view diff] case mismatch in snippet view article find links to article

variant of the ARNO Pleckstrin Homology Domain in complex with Ins(1,3,4,5)P4 1u29: Triglycine variant of the ARNO Pleckstrin Homology Domain in complex with

GRB10 (1,838 words) [view diff] exact match in snippet view article find links to article

localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma". J. Biol

PHLDB1 (390 words) [view diff] no match in snippet view article find links to article

Kular G, Downes CP, Alessi DR (October 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities"

PHLDB2 (287 words) [view diff] no match in snippet view article find links to article

Kular G, Downes CP, Alessi DR (October 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities"

SPTBN2 (755 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1wjm: Solution structure of pleckstrin homology domain of human beta III spectrin. 1wyq: Solution structure of the second CH domain of

RAB8B (424 words) [view diff] exact match in snippet view article find links to article

Bruyn KM, de Rooij J, Wolthuis RM, et al. (2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". J. Biol

OSBPL11 (412 words) [view diff] exact match in snippet view article find links to article

Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain

ELMO (protein) (439 words) [view diff] exact match in snippet view article

JF (November 2008). "An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac

SBF1 (541 words) [view diff] case mismatch in snippet view article find links to article

v t e PDB gallery 1v5u: Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse

Vincent Timmerman (245 words) [view diff] exact match in snippet view article find links to article

Pericak-Vance a, Nicholson G, Timmerman V, Vance M, Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease

CSNK2A2 (691 words) [view diff] exact match in snippet view article find links to article

2000). "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". J

PREX2 (484 words) [view diff] exact match in snippet view article find links to article

2005). "Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2".

PLEKHG4 (644 words) [view diff] exact match in snippet view article find links to article

1086/432518. PMC 1224530. PMID 16001362. "Entrez Gene: PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4". Flanigan

GNGT1 (920 words) [view diff] exact match in snippet view article find links to article

Ladak R, Swanson DA, et al. (2000). "PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer

MIS18A (575 words) [view diff] no match in snippet view article find links to article

Kular G, Downes CP, Alessi DR (Oct 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities"

SPTBN1 (997 words) [view diff] case mismatch in snippet view article find links to article

1btn: STRUCTURE OF THE BINDING SITE FOR INOSITOL PHOSPHATES IN A PH DOMAIN 1mph: PLECKSTRIN HOMOLOGY DOMAIN FROM MOUSE BETA-SPECTRIN, NMR, 50 STRUCTURES

CENTB2 (467 words) [view diff] no match in snippet view article find links to article

S, Currie RA, Campbell DG, et al. (2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities"

FERMT1 (852 words) [view diff] exact match in snippet view article find links to article

mutations in a new gene encoding a FERM family protein with a pleckstrin homology domain in Kindler syndrome". Hum. Mol. Genet. 12 (8): 925–35. doi:10

Rubicon homology domain (441 words) [view diff] exact match in snippet view article find links to article

& protein". www.uniprot.org. Retrieved 2022-05-31. "PLEKHM3 - Pleckstrin homology domain-containing family M member 3 - Homo sapiens (Human) - PLEKHM3

TRIO (gene) (1,025 words) [view diff] exact match in snippet view article

Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain". The Journal of Biological Chemistry. 282 (40): 29201–10. doi:10

MCF2L (681 words) [view diff] exact match in snippet view article find links to article

PMID 12376551. Cheng L, Mahon GM, Kostenko EV, Whitehead IP (Mar 2004). "Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange

OSBPL3 (639 words) [view diff] exact match in snippet view article find links to article

intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain

Ubiquitin-fold modifier conjugating enzyme 1 (489 words) [view diff] exact match in snippet view article find links to article

binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are

SOS1 (3,595 words) [view diff] exact match in snippet view article find links to article

D, Cowburn D (November 1997). "The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association

CLNS1A (1,161 words) [view diff] exact match in snippet view article find links to article

Tilly BC, Konrat R, Paulmichl M (2005). "ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor

PRKCB1 (675 words) [view diff] exact match in snippet view article find links to article

PMID 11278382. Yang XL, Zhang YL, Lai ZS, Xing FY, Liu YH (April 2003). "Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects

PLCD4 (821 words) [view diff] exact match in snippet view article find links to article

PMID 14702039. Lee SB, Várnai P, Balla A, et al. (2004). "The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical

SLK (gene) (969 words) [view diff] exact match in snippet view article

p21-activated kinase (PAK), germinal center kinases (GCK) and Pleckstrin homology domain containing PAK (PHPAK). SLK gene plays an important role in development

Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article

PMID 9671211. Waldron RT, Iglesias T, Rozengurt E (1999). "The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform

Suzanne Scarlata (731 words) [view diff] exact match in snippet view article find links to article

McLaughlin, Stuart; Rebecchi, Mario J. (December 1995). "The pleckstrin homology domain of phospholipase C-.delta.1 binds with high affinity to phosphatidylinositol

Ketan J. Patel (1,503 words) [view diff] exact match in snippet view article find links to article

K. L.; Thomas, J. E. (2007). "A transforming mutation in the pleckstrin homology domain of AKT1 in cancer". Nature. 448 (7152): 439–44. Bibcode:2007Natur

SH2B2 (994 words) [view diff] case mismatch in snippet view article find links to article

Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS 1v5m: Solution Structure of the Pleckstrin Homology Domain of Mouse APS

LSM4 (726 words) [view diff] exact match in snippet view article find links to article

Schedlbauer A, Gandini R, et al. (2005). "ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor

Dedicator of cytokinesis protein 4 (1,495 words) [view diff] case mismatch in snippet view article find links to article

et al. (September 2008). "An Alpha-Helical Extension of the ELMO1 Pleckstrin Homology Domain Mediates Direct Interaction to DOCK180 and Is Critical in Rac

Dedicator of cytokinesis protein 9 (1,047 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1wg7: Solution structure of pleckstrin homology domain from human KIAA1058 protein

DOK1 (1,385 words) [view diff] exact match in snippet view article find links to article

is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking

RASA3 (862 words) [view diff] exact match in snippet view article find links to article

Reynolds JS, et al. (2000). "GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association". J. Biol

GRB7 (1,581 words) [view diff] exact match in snippet view article find links to article

localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma". The

ITK (gene) (1,508 words) [view diff] exact match in snippet view article

which are often found in intracellular kinases: N-terminus – PH (pleckstrin homology domain) TH – Tec family homology domain (including Bruton's tyrosine

Granulosa cell tumour (1,249 words) [view diff] no match in snippet view article find links to article

juvenile granulosa cell tumours. In-frame duplications in the pleckstrin-homology domain of the protein were found in more than 60% of juvenile granulosa

T-cell lymphoma invasion and metastasis-inducing protein 1 (1,315 words) [view diff] exact match in snippet view article find links to article

membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal

Casein kinase 2, alpha 1 (1,175 words) [view diff] exact match in snippet view article find links to article

2000). "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". J

AKT2 (1,549 words) [view diff] case mismatch in snippet view article find links to article

WITH AMP-PNP AND GSK3 PEPTIDE 1p6s: Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt) 2jdo: STRUCTURE OF PKB-BETA

Avery August (1,055 words) [view diff] case mismatch in snippet view article find links to article

Inducible T cell Kinase (ITK) requires PI3 kinase activity and the Pleckstrin Homology domain of inducible T cell kinase." (1997) Proc. Natl. Acad. Sci. 94:

Phosphatidylinositol 4,5-bisphosphate (2,042 words) [view diff] exact match in snippet view article find links to article

1038/374173a0. PMID 7877690. S2CID 4365980. Holz RW, et al. (2000). "A pleckstrin homology domain specific for phosphatidylinositol 4, 5-bisphosphate (PtdIns-4

Eukaryotic translation elongation factor 1 alpha 1 (2,672 words) [view diff] exact match in snippet view article find links to article

Suh PG (May 2002). "Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity". The

Ceramide kinase (1,881 words) [view diff] exact match in snippet view article find links to article

"Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain". Biochem. Biophys. Res. Commun. 324 (4): 1215–9. doi:10.1016/j

Dedicator of cytokinesis protein 1 (2,406 words) [view diff] case mismatch in snippet view article find links to article

Laurin M, et al. (2008). "An α-Helical Extension of the ELMO1 Pleckstrin Homology Domain Mediates Direct Interaction to DOCK180 and Is Critical in Rac

RALA (2,012 words) [view diff] exact match in snippet view article find links to article

Wesenbeek J, Cool RH, Wittinghofer AH, Bos JL (Sep 2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". The Journal

Lewis C. Cantley (3,257 words) [view diff] case mismatch in snippet view article find links to article

signaling downstream of PI-3-kinase. They discovered that the Pleckstrin Homology domain of AKT binds to PtdIns(3,4,5)P3 (and PtdIns(3,4)P2) and that this

NBEAL1 (1,432 words) [view diff] case mismatch in snippet view article find links to article

acid 1886 until amino acid 1983, this domain is referred to as a Pleckstrin Homology domain in the BEACH domain. It has a PH because the fold of this domain

CSNK2B (2,258 words) [view diff] exact match in snippet view article find links to article

2000). "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". J

Akt/PKB signaling pathway (4,116 words) [view diff] exact match in snippet view article find links to article

independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation". J Biol Chem. 286 (43): 37389–98

PTPN11 (4,300 words) [view diff] exact match in snippet view article find links to article

PMID 11782427. Zhao C, Yu DH, Shen R, Feng GS (July 1999). "Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK

Phosphatidylinositol 3,4-bisphosphate (2,104 words) [view diff] case mismatch in snippet view article find links to article

Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

BAG3 (3,610 words) [view diff] exact match in snippet view article find links to article

Suh PG (May 2002). "Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity" (PDF)

PLCG1 (3,828 words) [view diff] exact match in snippet view article find links to article

Suh PG (May 2002). "Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity". The

Shapiro–Senapathy algorithm (6,804 words) [view diff] exact match in snippet view article find links to article

behavioral problems caused by a homozygous deletion of the SPTBN2 pleckstrin homology domain". American Journal of Medical Genetics Part A. 173 (9): 2494–2499

PAK1 (5,251 words) [view diff] case mismatch in snippet view article find links to article

Kim YB, Shin YJ, Roy A, Kim JH (August 2015). "The Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase

GRB2 (9,365 words) [view diff] exact match in snippet view article find links to article

PMID 11782427. Zhao C, Yu DH, Shen R, Feng GS (July 1999). "Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK