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Longer titles found: Vicarious nucleophilic substitution (view)

searching for Nucleophilic substitution 67 found (189 total)

alternate case: nucleophilic substitution

Carboxylate (492 words) [view diff] no match in snippet view article find links to article

A carboxylate is the conjugate base of a carboxylic acid. Carboxylate salts have the general formula M(RCOO)n, where M is a metal and n is 1, 2,...; carboxylate
Quinazoline (1,049 words) [view diff] no match in snippet view article find links to article
Quinazoline is an organic compound with the formula C8H6N2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered
Corey–House synthesis (1,498 words) [view diff] exact match in snippet view article find links to article
can react directly (without copper) with an alkyl halide in a nucleophilic substitution reaction to form a new carbon–carbon bond. However, aside from
Radical-nucleophilic aromatic substitution (454 words) [view diff] no match in snippet view article find links to article
1002/0471264180.or054.01 Evidence for a radical mechanism of aromatic "nucleophilic" substitution Joseph F. Bunnett and Jhong Kook Kim J. Am. Chem. Soc.; 1970;
Haloalkane (2,448 words) [view diff] exact match in snippet view article find links to article
product is usually colorless and odorless. Alcohol undergoes nucleophilic substitution reaction by halogen acid to give Haloalkanes. Tertiary alkanol
Shiina esterification (1,449 words) [view diff] exact match in snippet view article find links to article
attacked by a hydroxyl group in alcohol through intermolecular nucleophilic substitution. Simultaneously, residual aromatic carboxylic acid salt, which
Acetoacetic ester synthesis (119 words) [view diff] exact match in snippet view article find links to article
conjugated and thus resonance stabilized. The carbon then undergoes nucleophilic substitution. When heated with aqueous acid, the newly alkylated ester is hydrolyzed
Ether (1,762 words) [view diff] exact match in snippet view article find links to article
ethers: 2 R–OH → R–O–R + H2O at high temperature This direct nucleophilic substitution reaction requires elevated temperatures (about 125 °C). The reaction
Prévost reaction (210 words) [view diff] exact match in snippet view article find links to article
(2) with an alkene gives another short-lived iodinium salt (3). Nucleophilic substitution (SN2) by the benzoate salt gives the ester (4). Another silver
Glybuzole (886 words) [view diff] exact match in snippet view article find links to article
and pyridine. The reaction that will proceed is a bimolecular nucleophilic substitution reaction (SN2) (Figure 2). The nitrogen atom from the amino-group
Shiina macrolactonization (1,152 words) [view diff] exact match in snippet view article find links to article
attacked by a hydroxyl group in the seco acid through intramolecular nucleophilic substitution. Simultaneously, residual aromatic carboxylic acid salt, which
Sulfonium (448 words) [view diff] exact match in snippet view article find links to article
to the methyl group. At the same time, as part of a concerted nucleophilic substitution mechanism (SN2), the iodide leaving group departs. This leaves
Non-nucleophilic base (354 words) [view diff] exact match in snippet view article find links to article
enolate in the Claisen ester condensation, instead of undergoing a nucleophilic substitution. This reaction (deprotonation with LDA) is commonly used to generate
Transamination (559 words) [view diff] exact match in snippet view article find links to article
second type of transamination reaction can be described as a nucleophilic substitution of one amine or amide anion on an amine or ammonium salt. For
Electrophilic amination (1,803 words) [view diff] exact match in snippet view article find links to article
latter reagent is more efficient than bromination followed by nucleophilic substitution by the azide anion Palladium on carbon and hydrogen gas reduce
Diol (1,066 words) [view diff] exact match in snippet view article find links to article
protonation of the hydroxyl group. Then, followed by intramolecular nucleophilic substitution, the second hydroxyl group attacks the electron deficient carbon
Ingrid del Carmen Montes González (1,261 words) [view diff] case mismatch in snippet view article find links to article
Engineering News, 87(44), June 22, 2009. “Counterion Effects in the Nucleophilic Substitution Reaction of the Acetate Ion with Alkyl Bromides in the Synthesis
Triazavirin (550 words) [view diff] exact match in snippet view article find links to article
Ulomskii EN, Medvedeva NR, Egorov VV, Kiselev OI, et al. (2015). "Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential
Hantzsch pyrrole synthesis (536 words) [view diff] exact match in snippet view article find links to article
(3) attacks the α-carbon of the α-haloketone (4) as part of a nucleophilic substitution, instead of attacking the carbonyl carbon. A generalization of
Organocobalt chemistry (849 words) [view diff] exact match in snippet view article find links to article
and at the same time the alpha-carbon position is activated for nucleophilic substitution. Cobalt compounds react with dialkynes and dienes to cyclic intermediates
Oxidative addition (1,197 words) [view diff] exact match in snippet view article find links to article
oxidative additions proceed analogously to the well known bimolecular nucleophilic substitution reactions in organic chemistry. Nucleophillic attack by the metal
Thiazole (1,053 words) [view diff] exact match in snippet view article find links to article
primary site for electrophilic substitution, and C2 as the site for nucleophilic substitution. Thiazoles are found in a variety of specialized products, often
Phosphonium (904 words) [view diff] case mismatch in snippet view article find links to article
Jennings, EV; Nikitin, K; Ortin, Y; Gilheany, DG (2014). "Degenerate Nucleophilic Substitution in Phosphonium Salts". J. Am. Chem. Soc. 136 (46): 16217–16226
Appel reaction (615 words) [view diff] case mismatch in snippet view article find links to article
William; Poulton, Andrew (2011). "Catalytic Phosphorus(V)-Mediated Nucleophilic Substitution Reactions: Development of a Catalytic Appel Reaction". Journal
Sulfenamide (739 words) [view diff] exact match in snippet view article find links to article
HCl The S-N bond formation generally obeys standard bimolecular nucleophilic substitution rules, with the basic nitrogen centre being the nucleophile. Primary
Von Richter reaction (591 words) [view diff] exact match in snippet view article find links to article
J. F. Bunnett (1958). "Mechanism and reactivity in aromatic nucleophilic substitution reactions". Quarterly Reviews, Chemical Society. 12 (1): 1–16
Trifluoromethanesulfonyl azide (306 words) [view diff] exact match in snippet view article find links to article
highly explosive azido-chloromethane and diazidomethane in situ by nucleophilic substitution on dichloromethane. Moreover, the volatility of dichloromethane
2,4,6-Tris(trinitromethyl)-1,3,5-triazine (147 words) [view diff] case mismatch in snippet view article
doi:10.1070/MC1995v005n01ABEH000440. Shastin, A. V. (2003). "Nucleophilic Substitution Reactions of 2,4,6-Tris(trinitromethyl)-1,3,5-triazine. 3. Reaction
3-Nitrochlorobenzene (283 words) [view diff] exact match in snippet view article find links to article
isomers of nitrochlorobenzene, the meta isomer is not activated to nucleophilic substitution at the chlorine center. However, 3-nitrochlorobenzene has other
2,4-Dinitrochlorobenzene (389 words) [view diff] exact match in snippet view article find links to article
virtue of the two nitro groups, the chloride is susceptible to nucleophilic substitution. In this way, the compound is a precursor to many other compounds
William Gould Young (699 words) [view diff] case mismatch in snippet view article find links to article
(1951). "Allylic Rearrangements. XXIX. Relative Tendencies of Nucleophilic Substitution in Organic Halides". Journal of the American Chemical Society
Sulfonic acid (1,628 words) [view diff] case mismatch in snippet view article find links to article
Bunnett, Joseph F.; Zahler, Roland E. (1951-10-01). "Aromatic Nucleophilic Substitution Reactions". Chemical Reviews. 49 (2): 273–412. doi:10.1021/cr60153a002
Hammond's postulate (2,551 words) [view diff] exact match in snippet view article find links to article
methyl transition state is very far to the right. Bimolecular nucleophilic substitution (SN2) reactions are concerted reactions where both the nucleophile
Cyclopropenium ion (1,000 words) [view diff] exact match in snippet view article find links to article
formation of a peptide bond via acid chloride formation followed by nucleophilic substitution with the unprotected amino acid. This method of mildly generating
P-Toluenesulfonic acid (609 words) [view diff] case mismatch in snippet view article find links to article
77 (15): 4183–4184. doi:10.1021/ja01620a078. ISSN 0002-7863. "Nucleophilic Substitution". L. Field and J. W. McFarland (1963). "p-Toluenesulfonic Anhydride"
Three-center four-electron bond (1,187 words) [view diff] exact match in snippet view article find links to article
serve as models for studying the transition states of bimolecular nucleophilic substitution reactions. Hypervalent molecule Greenwood, Norman N.; Earnshaw
Selectfluor (881 words) [view diff] exact match in snippet view article find links to article
1039/C39920000595. Differring, Edmond; Wehrli, Markus (1991). "Nucleophilic substitution versus electron transfer: 2. SN2 at fluoride and electron transfer
Bargellini reaction (1,005 words) [view diff] exact match in snippet view article find links to article
attack the oxirane due to formation of tertiary carbocation in a nucleophilic substitution SN1 concerted elimination of one atom of chlorine. The nucleophilic
Cycloalkane (1,669 words) [view diff] exact match in snippet view article find links to article
hydrogenation. Medium rings exhibit larger rates in for example nucleophilic substitution reactions but smaller ones in ketone reduction. This is due to
Dihydroxylation (1,822 words) [view diff] exact match in snippet view article find links to article
The anion from the corresponding silver salt is then added by nucleophilic substitution to the iodinium ion. In the Prévost reaction, the iodinium ion
Alkyne trimerisation (1,669 words) [view diff] exact match in snippet view article find links to article
functionalization of pre-formed aromatic compounds through electrophilic or nucleophilic substitution, the regioselectivity of which can sometimes be difficult to control
Carbonyl oxidation with hypervalent iodine reagents (1,207 words) [view diff] exact match in snippet view article find links to article
iodine(III) enolate intermediate forms, which then undergoes either nucleophilic substitution (α-functionalization), elimination (dehydrogenation), or rearrangement
Crich beta-mannosylation (809 words) [view diff] exact match in snippet view article find links to article
DTBMP (2,6-di-tert-butyl-4-methylpyridine) as a base, followed by nucleophilic substitution of glycosyl acceptors (HOR3) to provide the 1,2-cis-β-glycoside
Saccharin (2,751 words) [view diff] exact match in snippet view article find links to article
prepare exclusively disubstituted amines from alkyl halides via a nucleophilic substitution, followed by a Gabriel synthesis. Saccharose Sugar substitute
Stannylene (1,237 words) [view diff] case mismatch in snippet view article find links to article
Stannylene with Iodoalkanes, Enones, and Dienes. Inhibition of Nucleophilic Substitution at Tin(IV) Centers". Organometallics. 21: 2430–2437. Neumann,
Resorcinol (1,667 words) [view diff] exact match in snippet view article find links to article
electrophilic aromatic addition, resorcinol (and other poly-ols) undergo nucleophilic substitution via the enone tautomer. Nitration with concentrated nitric acid
RTI-274 (477 words) [view diff] exact match in snippet view article find links to article
(2002). "Rearrangement of a mesylate tropane intermediate in nucleophilic substitution reactions. Synthesis of aza-bicyclo3.2.1octane and aza-bicyclo3
Fluorinase (1,027 words) [view diff] exact match in snippet view article find links to article
pathway of salinosporamide A. The fluorinase catalyses an SN2-type nucleophilic substitution at the C-5' position of SAM, while L-methionine acts as a neutral
Skeletal formula (3,452 words) [view diff] exact match in snippet view article find links to article
phthalimide-1-yl group Sulfonate esters are often leaving groups in nucleophilic substitution reactions. See the articles on sulfonyl and sulfonate groups for
1,2-Dimethyldiborane (1,606 words) [view diff] exact match in snippet view article find links to article
Blay, N. J. (1960). "970. Boron hydride derivatives. Part V. Nucleophilic substitution in decaborane". Journal of the Chemical Society (IV): 5012–5015
Nicolaou Taxol total synthesis (1,905 words) [view diff] exact match in snippet view article find links to article
alcohol 6.2. The Taxol ring (D) was added by an intramolecular nucleophilic substitution involving this hydroxyl group to give oxetane 6.3. After acetylation
Diazonium compound (3,645 words) [view diff] exact match in snippet view article find links to article
+ N2 + Cu+}}} The cyano group usually cannot be introduced by nucleophilic substitution of haloarenes, but such compounds can be easily prepared from
George S. Hammond (3,719 words) [view diff] case mismatch in snippet view article find links to article
Learning. p. 333. Curtis, Rachael (October 2, 2013). "Kinetics of Nucleophilic Substitution Reactions". Chemwiki. UCDavis. Retrieved November 21, 2015. Justik
Oxocarbenium (2,168 words) [view diff] case mismatch in snippet view article find links to article
Tabacco, S. A.; Woerpel, K. A. (1999), "Stereochemical Reversal of Nucleophilic Substitution Reactions Depending upon Substituent: Reactions of Heteroatom-Substituted
Fluorographene (1,766 words) [view diff] exact match in snippet view article find links to article
mobility increases significantly. Fluorographene is susceptible for nucleophilic substitution and reductive defluorination, which makes it an extraordinary
Aryldialkylphosphatase (2,087 words) [view diff] exact match in snippet view article find links to article
PTE is also located. Catalysis of organophosphates occurs via a nucleophilic substitution with inversion of configuration (SN2 mechanism) about the phosphorus
Potassium iodide (5,266 words) [view diff] exact match in snippet view article find links to article
iodides are in turn used to attach aryl groups to other organics by nucleophilic substitution, with iodide ion as the leaving group. Potassium iodide is an
Reactions of organocopper reagents (1,724 words) [view diff] exact match in snippet view article find links to article
the corresponding lower-order cyanocuprates. The mechanism of nucleophilic substitution by lower-order organocuprates depends in a profound way on the
Organofluorine chemistry (4,534 words) [view diff] exact match in snippet view article find links to article
fluorides, e.g. fluoroanilines and fluorophenols, often undergo nucleophilic substitution efficiently. Formally, fluorocarbons only contain carbon and fluorine
Trifluoroperacetic acid (3,232 words) [view diff] exact match in snippet view article find links to article
"Polyfluoroaryl organometallic compounds. Part VIII. Synthesis of and nucleophilic substitution in octafluorodibenzofuran". J. Chem. Soc. C: 1560–1565. doi:10
BRAF (gene) (5,523 words) [view diff] exact match in snippet view article
oxygen atom on the γ-phosphate group of ATP through bimolecular nucleophilic substitution. The kinase (CR3) domain of human Raf kinases is inhibited by
Transition state theory (5,315 words) [view diff] exact match in snippet view article find links to article
Figure 1: Reaction coordinate diagram for the bimolecular nucleophilic substitution (SN2) reaction between bromomethane and the hydroxide anion
Energy profile (chemistry) (3,490 words) [view diff] case mismatch in snippet view article
Robert C. Neuman, Jr. pp. Ch.7, 1–71. Organic Chemistry Portal. "Nucleophilic Substitution". Retrieved 2013-10-25. Silverman, Richard (2004). The Organic
4-Ipomeanol (3,272 words) [view diff] exact match in snippet view article find links to article
alcohol group is a strongly basic leaving group that cannot undergo nucleophilic substitution reactions. However, it becomes a better leaving group after protonation
Plumbylene (3,055 words) [view diff] exact match in snippet view article find links to article
the electron-deficient lead.27 Plumbylenes are known to undergo nucleophilic substitution with organometallic reagents to form transmetallated products
2-Norbornyl cation (5,927 words) [view diff] case mismatch in snippet view article find links to article
D. (ed.). Reaction Mechanisms in Organic Chemistry. Volume I: Nucleophilic Substitution at a Saturated Carbon Atom. Amsterdam: Elsevier Publishing Company
Aza-Cope rearrangement (5,685 words) [view diff] exact match in snippet view article find links to article
6-dihydropyridinium salt adducts. Synthons for general electrophilic and nucleophilic substitution of the piperidine ring system". J. Am. Chem. Soc. 102 (3): 1064–1082