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searching for Mitophagy 33 found (55 total)

alternate case: mitophagy

Whi2 (251 words) [view diff] exact match in snippet view article find links to article

nutrient availability on to stress responsive elements and autophagy/mitophagy mechanisms. It is encoded by a 1.46 kbp gene located on chromosome 15
PINK1 (2,650 words) [view diff] exact match in snippet view article find links to article
Springer W, Kahle PJ (March 2011). "Regulation of PINK1-Parkin-mediated mitophagy". Autophagy. 7 (3): 266–78. doi:10.4161/auto.7.3.14348. PMID 21187721
MFN2 (1,027 words) [view diff] exact match in snippet view article find links to article
Langerhans and can inhibit mitochondrial quality control mechanisms such as mitophagy and autophagy - leading to a defect in insulin secretion and eventual
Mitochondrial permeability transition pore (3,457 words) [view diff] exact match in snippet view article find links to article
causing ROS-producing mitochondria to undergo selective lysosome-dependent mitophagy during nutrient starvation conditions. Under severe stress/pathologic
HDAC6 (1,433 words) [view diff] exact match in snippet view article find links to article
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization • positive regulation of mitophagy in response to mitochondrial depolarization
TSC2 (1,818 words) [view diff] exact match in snippet view article find links to article
positive regulation of macroautophagy • anoikis • negative regulation of mitophagy • negative regulation of TOR signaling • protein kinase B signaling Sources:Amigo
ATG8 (2,062 words) [view diff] exact match in snippet view article find links to article
phosphorylated by protein kinase A to suppress participation in autophagy/mitophagy. Other homologues are the transport factor GATE-16 (Golgi-associated ATPase
RNF41 (636 words) [view diff] exact match in snippet view article find links to article
protein autoubiquitination • apoptotic process • negative regulation of mitophagy • positive regulation of protein catabolic process Sources:Amigo / QuickGO
SMURF1 (965 words) [view diff] exact match in snippet view article find links to article
pathway, planar cell polarity pathway • parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization • substrate localization to
VDAC3 (2,521 words) [view diff] exact match in snippet view article find links to article
observed to target Parkin to defective mitochondria to eliminate them by mitophagy. Failure to eliminate these mitochondria result in the accumulation of
HSPA1L (2,268 words) [view diff] exact match in snippet view article find links to article
"High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy". Nature. 504 (7479): 291–5. doi:10.1038/nature12748. PMC 5841086. PMID 24270810
BNIP3 (2,663 words) [view diff] exact match in snippet view article find links to article
PA (July 2009). "Role of BNIP3 and NIX in cell death, autophagy, and mitophagy". Cell Death and Differentiation. 16 (7): 939–46. doi:10.1038/cdd.2009
BECN1 (1,399 words) [view diff] exact match in snippet view article find links to article
positive regulation of autophagosome assembly • autophagy of mitochondrion • mitophagy • autophagy • positive regulation of autophagy • response to mitochondrial
Respirasome (1,512 words) [view diff] exact match in snippet view article find links to article
(2009). "Coenzyme Q deficiency triggers mitochondria degradation by mitophagy". Autophagy. 5 (1): 19–33. doi:10.4161/auto.5.1.7174. hdl:10261/40287
Autophagy-related protein 13 (828 words) [view diff] exact match in snippet view article find links to article
assembly • positive regulation of protein targeting to mitochondrion • mitophagy • response to mitochondrial depolarisation • regulation of macroautophagy
LRRK2 (1,874 words) [view diff] exact match in snippet view article find links to article
imbalance, leading to excess mitochondrial clearance from dendrites by mitophagy. LRRK2 is also a substrate for chaperone-mediated autophagy. Mutations
Sequestosome 1 (1,854 words) [view diff] exact match in snippet view article find links to article
transcription from RNA polymerase II promoter • protein phosphorylation • mitophagy • response to mitochondrial depolarisation • macroautophagy • endosome
Optineurin (1,401 words) [view diff] exact match in snippet view article find links to article
to plasma membrane protein transport • parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization • positive regulation of xenophagy
HtrA serine peptidase 2 (1,919 words) [view diff] exact match in snippet view article find links to article
organization • cellular response to oxidative stress • negative regulation of mitophagy in response to mitochondrial depolarization • positive regulation of cysteine-type
PPARGC1A (2,796 words) [view diff] exact match in snippet view article find links to article
DA (2015). "Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle". American Journal of Physiology. 308 (9): C710-719
CLEC16A (1,647 words) [view diff] exact match in snippet view article find links to article
ubiquitin-dependent protein catabolic process • negative regulation of mitophagy • cellular response to starvation • negative regulation of autophagosome
CDC37 (1,485 words) [view diff] exact match in snippet view article find links to article
interferon-gamma-mediated signaling pathway • positive regulation of mitophagy in response to mitochondrial depolarization • regulation of protein kinase
ATM serine/threonine kinase (4,666 words) [view diff] exact match in snippet view article find links to article
mitochondrial homeostasis, as a regulator of mitochondrial autophagy (mitophagy) whereby old, dysfunctional mitochondria are removed. Increased ATM activity
Pseudomonas aeruginosa (7,250 words) [view diff] exact match in snippet view article find links to article
ISSN 1876-0341. PMID 30459101. Kirienko NV, Ausubel FM, Ruvkun G (February 2015). "Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa"
FBXO7 (1,430 words) [view diff] exact match in snippet view article find links to article
Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy". Nature Neuroscience. 16 (9): 1257–65. doi:10.1038/nn.3489. PMC 3827746
Complications of diabetes (5,204 words) [view diff] exact match in snippet view article find links to article
risk". CNN. 2011-09-19. Kobayashi S, Liang Q (May 2014). "Autophagy and mitophagy in diabetic cardiomyopathy". Biochim Biophys Acta. S0925-4439 (14): 148–43
P53 (13,589 words) [view diff] exact match in snippet view article find links to article
cycle arrest • positive regulation of cell aging • negative regulation of mitophagy • regulation of mitochondrial membrane permeability involved in apoptotic
Pyoverdine (3,877 words) [view diff] exact match in snippet view article find links to article
Kirienko, Natalia V.; Ausubel, Frederick M.; Ruvkun, Gary (2015-02-10). "Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa"
Cancer stem cell (9,244 words) [view diff] exact match in snippet view article find links to article
Łos MJ (September 2013). "Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer
TP53-inducible glycolysis and apoptosis regulator (3,415 words) [view diff] exact match in snippet view article find links to article
6-bisphosphate metabolic process • autophagy • negative regulation of mitophagy • cellular response to cobalt ion • response to ischemia • fructose 2
Chandrima Shaha (2,202 words) [view diff] exact match in snippet view article find links to article
1007/s11010-017-3267-7(2018). Kumar, A and Shaha, C*. SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation
Patrick Purdon (2,243 words) [view diff] exact match in snippet view article find links to article
Richard J (ed.). "Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila". eLife. 7: e35878. doi:10.7554/eLife.35878. PMC 6008047
Thirumala-Devi Kanneganti (3,914 words) [view diff] exact match in snippet view article find links to article
Ramnik J. (May 2013). "Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection". Nature Immunology