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searching for Mesothelin 12 found (28 total)

alternate case: mesothelin

CD28 family receptor (1,292 words) [view diff] exact match in snippet view article find links to article

response to a type of carcinomas called mesothelin. These T cells have a high affinity for human mesothelin. Upon mesothelin stimulation, the T cells proliferate

Malignant pleural effusion (1,147 words) [view diff] exact match in snippet view article find links to article

metalloproteinases and tumour markers such as carcinoembryonic antigen. Pleural fluid mesothelin has a sensitivity of 71%, greater than that of cytology, and a specificity

Monoclonal antibody (4,801 words) [view diff] exact match in snippet view article find links to article

affinity monoclonal antibodies recognize non-overlapping epitopes on mesothelin for monitoring and treating mesothelioma". Scientific Reports. 5: 9928

Asbestos-related diseases (2,556 words) [view diff] exact match in snippet view article find links to article

chemotherapy or multimodality treatment. Several tumour biomarkers (soluble mesothelin-related protein (SMRP), osteopontin and fibulin3) have been evaluated

Single-domain antibody (3,898 words) [view diff] exact match in snippet view article find links to article

Human single-domain antibodies targeting various tumor antigens including mesothelin, GPC2 and GPC3 were isolated by phage display. The HN3 human single-domain

Michel Sadelain (2,399 words) [view diff] exact match in snippet view article find links to article

Biotherapeutics, Inc. for a product candidate to treat malignant mesothelioma using mesothelin-targeted CAR T cells named icasM28z. In 2013, Sadelain co-founded Juno

Elizabeth Jaffee (1,022 words) [view diff] exact match in snippet view article find links to article

Diagnostic Biomarkers and Therapeutic Targets For Pancreatic Cancer, Mesothelin Vaccines and Model Systems, Annexina2 as Immunological Target, and Prostate

Folate targeting (3,023 words) [view diff] exact match in snippet view article find links to article

C, et al. (June 2007). "Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma". Gynecol. Oncol. 105 (3):

Coronary artery disease (10,701 words) [view diff] exact match in snippet view article find links to article

hair cells, and mutations lead to deafness. Steriocilin is a partner to mesothelin (MSN), a related super-helical protein, whose transcript is also modulated

Patient derived xenograft (3,156 words) [view diff] exact match in snippet view article find links to article

growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells". Protein & Cell. 8 (12): 926–931. doi:10.1007/s13238-017-0472-9

Raja M. Flores (1,801 words) [view diff] exact match in snippet view article find links to article

Gonzalez-Espinoza, R; Bott, M; Ladanyi, M; Rusch, V; Fleisher, M (Feb 2010). "Soluble mesothelin related peptides (SMRP) and osteopontin as protein biomarkers for malignant

Polymer-protein hybrid (4,985 words) [view diff] exact match in snippet view article find links to article

Mitchell; Beers, Richard; Zhao, Hong (May 2007). "Releasable PEGylation of Mesothelin Targeted Immunotoxin SS1P Achieves Single Dosage Complete Regression of