Find link

language:

Find link is a tool written by Edward Betts.

searching for Inflammasome 86 found (177 total)

DPP9 (982 words) [view diff] exact match in snippet view article find links to article

with the NLRP1 protein and affects the level of activation of the NLRP1 inflammasome. This function involves binding to a complex of full-length NLRP1 and

Caspase 12 (636 words) [view diff] exact match in snippet view article find links to article

signaling pathway Cellular component NLRP3 inflammasome complex AIM2 inflammasome complex IPAF inflammasome complex endoplasmic reticulum cytoplasm Biological

NLRP2 (1,498 words) [view diff] exact match in snippet view article find links to article

Vaccari JP, Keane RW (July 2013). "Human astrocytes express a novel NLRP2 inflammasome". Glia. 61 (7): 1113–21. doi:10.1002/glia.22499. PMID 23625868. S2CID 24606692

Scaffold protein (2,156 words) [view diff] exact match in snippet view article find links to article

Dostert, Catherine; Muruve, Daniel A; Tschopp, Jürg (December 2007). "The inflammasome: a danger sensing complex triggering innate immunity". Current Opinion

Janelle Ayres (1,361 words) [view diff] exact match in snippet view article find links to article

coli involves inflammasome and IGF-1 signaling. (2015) Science. 350(6260):558-63. DOI: 10.1126/science.aac6468 Ayres, J.S. Inflammasome-microbiota interplay

Perfluorodecanoic acid (3,380 words) [view diff] exact match in snippet view article find links to article

concentration dependent manner. It also activated the NLP3 inflammasome. The inflammasome is crucial for induction of lipogenic genes expression in fatty

ARIH2 (772 words) [view diff] exact match in snippet view article find links to article

ubiquitination, ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages. GRCm38: Ensembl release 89: ENSMUSG00000064145

Tranilast (707 words) [view diff] exact match in snippet view article find links to article

types, in in vitro studies. It has also been shown to inhibit NALP3 inflammasome activation and is being studied as a treatment for NALP3-driven inflammatory

ZBP1 (831 words) [view diff] exact match in snippet view article find links to article

"ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2): aag2045

Caspase recruitment domain-containing protein 8 (566 words) [view diff] exact match in snippet view article find links to article

Martinon F, Burns K, et al. (2004). "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder". Immunity

Rickettsia australis (816 words) [view diff] exact match in snippet view article find links to article

David H.; Fang, Rong (2016-06-30). "Rickettsia australis Activates Inflammasome in Human and Murine Macrophages". PLOS ONE. 11 (6): e0157231. Bibcode:2016PLoSO

Eran Elinav (2,495 words) [view diff] exact match in snippet view article find links to article

advised by Richard Anthony Flavell, in which he discovered the NLRP6 inflammasome. In 2012 Elinav moved to the Weizmann Institute of Science and in 2016

Ampelopsin (510 words) [view diff] exact match in snippet view article find links to article

DHM protects against DOX-induced cardiotoxicity by inhibiting NLRP3 inflammasome activation via stimulation of the SIRT1 pathway. In a trial of 60 patients

Candida albicans (9,890 words) [view diff] exact match in snippet view article find links to article

in humans is encoded by the GSDMD gene and is a known target of the inflammasome and acts as an effector molecule of programmed cell death known as pyroptosis

NLRP9 (342 words) [view diff] exact match in snippet view article find links to article

binding nucleotide binding protein binding Cellular component cytoplasm inflammasome complex Biological process positive regulation of interleukin-18 production

Rab (G-protein) (1,327 words) [view diff] exact match in snippet view article

Small-scale transport, promoter for tumor development RAB27 Extracellular vesicles, endosome RAB29 Recruits LRRK2 to TGN RAB39A Binds Caspase-1 in inflammasome

Toll-like receptor 4 (9,082 words) [view diff] exact match in snippet view article find links to article

Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation". Infection and Immunity

NLRC3 (243 words) [view diff] exact match in snippet view article find links to article

production involved in inflammatory response negative regulation of NLRP3 inflammasome complex assembly negative regulation of NIK/NF-kappaB signaling intracellular

LUBAC (1,247 words) [view diff] exact match in snippet view article find links to article

Additionally, LUBAC has been shown to interact with PKC and NLRP3/ASC inflammasome,. Antagonistic to LUBAC are deubiquitinases such as OTULIN or CYLD, of

Toll-like receptor 6 (1,073 words) [view diff] exact match in snippet view article find links to article

structure receptor complex Biological process positive regulation of NLRP3 inflammasome complex assembly immune system process positive regulation of JUN kinase

Candidalysin (1,010 words) [view diff] exact match in snippet view article find links to article

intercalation and permeabilization. It causes IL-1β release and is a driver of inflammasome activation in macrophages. Epithelial immunity can recognize Ece1-III62–92K

Protein kinase R (4,105 words) [view diff] exact match in snippet view article find links to article

This metabolically activated inflammatory complex is called metabolic inflammasome or metaflammasome. Via the JNK signaling pathway, PKR also plays a role

NLRP6 (325 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm nuclear membrane membrane plasma membrane inflammasome complex nucleus Biological process response to bacterium immune system

Muckle–Wells syndrome (553 words) [view diff] exact match in snippet view article find links to article

Lee WP, Weinrauch Y, et al. (March 2006). "Cryopyrin activates the inflammasome in response to toxins and ATP". Nature. 440 (7081): 228–32. Bibcode:2006Natur

Mohammad Zahid Ashraf (1,050 words) [view diff] exact match in snippet view article find links to article

Chatterjee, Tathagata; Prabhakar, Amit (2 May 2017). "Activation of NLRP3 inflammasome complex potentiates venous thrombosis in response to hypoxia". Proceedings

IFI16 (1,371 words) [view diff] exact match in snippet view article find links to article

Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses". PLOS Pathogens. 11 (6): e1005030. doi:10

Dientamoeba fragilis (1,301 words) [view diff] exact match in snippet view article find links to article

Interactions Protect from Mucosal Infections through Activation of the Inflammasome". Cell. 167 (2): 444–456.e14. doi:10.1016/j.cell.2016.08.076. PMC 5129837

Vitiligo (3,728 words) [view diff] exact match in snippet view article find links to article

S2CID 20038695. Lamkanfi M, Vande Walle L, Kanneganti TD (2011). "Deregulated inflammasome signaling in disease". Immunol Rev (Review). 243 (1): 163–73. doi:10

Bamboo charcoal (1,114 words) [view diff] exact match in snippet view article find links to article

"Bamboo Vinegar Decreases Inflammatory Mediator Expression and NLRP3 Inflammasome Activation by Inhibiting Reactive Oxygen Species Generation and Protein

Myxoma virus (1,006 words) [view diff] exact match in snippet view article find links to article

binding to the CARD protein, which is part of the caspase-1-activating inflammasome complex. By binding, it is able to inhibit apoptosis, which is normally

GBP5 (82 words) [view diff] exact match in snippet view article find links to article

inflammatory response inflammatory response positive regulation of NLRP3 inflammasome complex assembly protein homotetramerization positive regulation of innate

Heyndrickxia coagulans (1,153 words) [view diff] exact match in snippet view article find links to article

effects on mouse model of multiple sclerosis by altering the expression of inflammasome and IDO genes and modulation of T helper cytokine profile". Metabolic

Rhs toxins (627 words) [view diff] exact match in snippet view article find links to article

Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome". Proceedings of the National Academy of Sciences of the United States

Clare Bryant (770 words) [view diff] exact match in snippet view article find links to article

Katherine A Fitzgerald (26 August 2009). "Molecular mechanisms involved in inflammasome activation". Trends in Cell Biology. 19 (9): 455–464. doi:10.1016/J.TCB

Candida parapsilosis (1,166 words) [view diff] exact match in snippet view article find links to article

Vágvölgyi; Mihai G. Netea; Attila Gácser (2017). "Specific pathways mediating inflammasome activation by Candida parapsilosis". Scientific Reports. 7: 43129. Bibcode:2017NatSR

Cis-Urocanic acid (457 words) [view diff] exact match in snippet view article find links to article

Piippo N, Hytti M, Kaarniranta K, et al. (April 2020). "UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial

Glibenclamide (1,066 words) [view diff] exact match in snippet view article find links to article

Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia". Molecular Neurobiology. 59 (10): 6590–6607

FSTL1 (1,415 words) [view diff] exact match in snippet view article find links to article

Vockley J, Hirsch R (May 2014). "Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages". European Journal

Dicer (3,276 words) [view diff] exact match in snippet view article find links to article

loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88". Cell. 149 (4): 847–59. doi:10.1016/j.cell.2012.03.036. PMC 3351582

CNOT8 (930 words) [view diff] exact match in snippet view article find links to article

(2007). "Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation". Infect. Immun. 75 (3): 1484–92. doi:10.1128/IAI.01315-06

Macromolecular assembly (2,286 words) [view diff] exact match in snippet view article find links to article

1007/s00249-011-0683-6. PMID 21336521. S2CID 26027815. Monie TP (2017). "The Canonical Inflammasome: A Macromolecular Complex Driving Inflammation". Macromolecular Protein

CCL7 (2,531 words) [view diff] exact match in snippet view article find links to article

Samikkannu T, et al. (June 2016). "Effect of Cocaine on HIV Infection and Inflammasome Gene Expression Profile in HIV Infected Macrophages". Scientific Reports

Epstein–Barr virus (5,937 words) [view diff] exact match in snippet view article find links to article

et al. (August 2013). "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and

Mefenamic acid (2,495 words) [view diff] exact match in snippet view article find links to article

Fasolino V, et al. (August 2016). "Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models". Nature Communications

Shaden Kamhawi (479 words) [view diff] exact match in snippet view article find links to article

during Bites of Infected Sand Flies Augment Severity of Leishmaniasis via Inflammasome-Derived IL-1β. Cell Host & Microbe. 2018 Jan;23(1):134-143.e6 "PLOS Neglected

Intestinal epithelium (3,041 words) [view diff] exact match in snippet view article find links to article

intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond". Current Opinion in Gastroenterology. 26 (6): 583–590. doi:10

Ziad Mallat (311 words) [view diff] exact match in snippet view article find links to article

PATHOLOGIE CARDIOVASCULAIRE) (1996) Academic work Institutions University of Cambridge Inserm Main interests atherosclerosis inflammasome vascular aneurysms

Katherine A. Fitzgerald (907 words) [view diff] exact match in snippet view article find links to article

(2009). "AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC". Nature. 458 (7237): 514–518. Bibcode:2009Natur.458..514H.

Nicotinic acetylcholine receptor (4,756 words) [view diff] exact match in snippet view article find links to article

(August 2014). "α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release". Molecular Medicine

Indium tin oxide (4,238 words) [view diff] exact match in snippet view article find links to article

Particles Induce Pro-Inflammatory Responses In Vitro, in Part through Inflammasome Activation". PLOS ONE. 10 (4): e0124368. Bibcode:2015PLoSO..1024368B

Ionophore (4,297 words) [view diff] exact match in snippet view article find links to article

Núñez, Gabriel (27 June 2013). "K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter". Immunity. 38

Impact of the COVID-19 pandemic on neurological, psychological and other mental health outcomes (6,267 words) [view diff] exact match in snippet view article find links to article

implicated in the antiviral response to COVID-19, including the NLRP3 inflammasome, interleukin-6, and ACE-2. Reported prevalence of mental health disorders

Sirtuin 2 (3,418 words) [view diff] exact match in snippet view article find links to article

regulation of protein catabolic process negative regulation of NLRP3 inflammasome complex assembly negative regulation of oligodendrocyte progenitor proliferation

Menna Clatworthy (597 words) [view diff] exact match in snippet view article find links to article

2013). "The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation". Cell. 153 (2): 348–61. doi:10.1016/J.CELL.2013.02.054. ISSN 0092-8674

Salmonellosis (6,758 words) [view diff] exact match in snippet view article find links to article

Resident macrophages can also recognize flagellin and activate NLRC4 inflammasome complex to activate caspase-1 and IL-1β and IL-18 release. Recruited

Clostridium septicum (1,990 words) [view diff] exact match in snippet view article find links to article

Man, Si Ming (2022). "Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins". Science Immunology. 7 (71): eabm1803

Vomocytosis (1,549 words) [view diff] exact match in snippet view article find links to article

2019). "Fluorescent antibiotics, vomocytosis, vaccine candidates and the inflammasome". Clinical & Translational Immunology. 8 (11): e01083. doi:10.1002/cti2

Leducq Foundation (1,600 words) [view diff] exact match in snippet view article find links to article

; Reilly, M. P.; Libby, P.; Wang, N.; Tall, A. R. (2021). "The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis". Nature. 592 (7853):

CD36 (5,199 words) [view diff] exact match in snippet view article find links to article

kinase/NF-kappaB signaling response to stilbenoid positive regulation of NLRP3 inflammasome complex assembly low-density lipoprotein particle clearance lipid storage

Circadian rhythm (12,903 words) [view diff] exact match in snippet view article find links to article

ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome". Communications Biology. 2: 353. doi:10.1038/s42003-019-0595-z. PMC 6776554

William Bachovchin (1,320 words) [view diff] exact match in snippet view article find links to article

Inhibition Enhances CD8 T Cell Recruitment and Activates Intrahepatic Inflammasome in a Murine Model of Hepatocellular Carcinoma. Cancers, 13(21), 5495

PELP-1 (3,909 words) [view diff] exact match in snippet view article find links to article

J; Thiruvaiyaru, D; Vadlamudi, R; Zhang, Q; Brann, D (2016). "NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation

Postbiotic (1,356 words) [view diff] exact match in snippet view article find links to article

et al., Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice. Nutrients

PELP-1 (3,909 words) [view diff] exact match in snippet view article find links to article

J; Thiruvaiyaru, D; Vadlamudi, R; Zhang, Q; Brann, D (2016). "NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation

Cellular senescence (6,395 words) [view diff] exact match in snippet view article find links to article

et al. (August 2013). "A complex secretory program orchestrated by the inflammasome controls paracrine senescence". Nature Cell Biology. 15 (8): 978–990

Serum amyloid A1 (4,261 words) [view diff] exact match in snippet view article find links to article

for a number of cellular functions including the activation of NLRP3 inflammasomes. SAA1 has been found to interact with outer membrane protein A (ompA)

Living medicine (950 words) [view diff] exact match in snippet view article find links to article

response and kills tumor cells by inducing apoptosis. ⑧ The macrophage inflammasome is activated through contact with bacterial components (LPS and flagellin)

Julio Licinio (4,628 words) [view diff] exact match in snippet view article find links to article

Morrison, M.; Wesselingh, S. L.; Rogers, G. B.; Licinio, J. (June 2016). "Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome

Jennifer Stow (1,613 words) [view diff] exact match in snippet view article find links to article

M.J.; Stow, J.L.; Schroder, K. (2016). "The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists"

Gap junction (10,914 words) [view diff] exact match in snippet view article find links to article

Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy". International Journal

Bacterial therapy (1,430 words) [view diff] exact match in snippet view article find links to article

response and kills tumor cells by inducing apoptosis. ⑧ The macrophage inflammasome is activated through contact with bacterial components (LPS and flagellin)

Charles Vacanti (2,333 words) [view diff] exact match in snippet view article find links to article

the low pH of the ATP solution, rather than as its properties as an inflammasome. She then returned to Japan and continued this work at RIKEN. Vacanti

Roslyn Kemp (721 words) [view diff] exact match in snippet view article find links to article

Rades; P Rod Dunbar; Sarah Hook (1 April 2014). "Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants". Immunology &

Carcinogenesis (13,933 words) [view diff] exact match in snippet view article find links to article

"Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome". The Journal of Biological Chemistry. 286 (44): 38703–13. doi:10.1074/jbc

SUCNR1 (9,204 words) [view diff] exact match in snippet view article find links to article

Cosín-Roger J (February 2022). "SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis". Biomedicines

Adipose tissue macrophages (2,339 words) [view diff] exact match in snippet view article find links to article

Rodeheffer, Matthew S.; Schultze, Joachim L.; Deep Dixit, Vishwa (2017). "Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during

Giulio Maria Pasinetti (3,281 words) [view diff] exact match in snippet view article find links to article

and characterization of small molecule inhibitors of NLRP3 and NLRC4 inflammasomes". Journal of Biological Chemistry. 296: 100597. doi:10.1016/j.jbc.2021

Sidonia Făgărășan (490 words) [view diff] exact match in snippet view article find links to article

facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome". Nature Communications. 6 (1): 6734. Bibcode:2015NatCo...6.6734M. doi:10

Jos van der Meer (1,558 words) [view diff] exact match in snippet view article find links to article

2010). "Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease". Proceedings

Chromosome 5 open reading frame 47 (1,178 words) [view diff] exact match in snippet view article find links to article

R, Kesner J, Rabadan R, Shapira SD (April 2017). "Germ-Cell-Specific Inflammasome Component NLRP14 Negatively Regulates Cytosolic Nucleic Acid Sensing

Bruce Beutler (12,100 words) [view diff] exact match in snippet view article find links to article

and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component". Nature Immunology. 17 (3): 250–258. doi:10.1038/ni.3333.

Inositol-trisphosphate 3-kinase (2,885 words) [view diff] exact match in snippet view article find links to article

Yeung RS (November 2016). "Inositol-Triphosphate 3-Kinase C Mediates Inflammasome Activation and Treatment Response in Kawasaki Disease". Journal of Immunology

Alzheimer's disease in African Americans (4,448 words) [view diff] exact match in snippet view article find links to article

of African Americans compared to Caucasians. Furthermore, the NLPR3 inflammasome that is thought to be critically involved in AD has increased activation

Innate lymphoid cell (10,510 words) [view diff] exact match in snippet view article find links to article

2014). "Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity". Nature Medicine

GPATCH2L (1,901 words) [view diff] exact match in snippet view article find links to article

DDX10 Probable ATP-dependent RNA helicase DDX10 1) it promotes AIM2-inflammasome activation by maintaining AIM2 protein stability. 2) it promotes human

Genome-wide CRISPR-Cas9 knockout screens (6,164 words) [view diff] exact match in snippet view article find links to article

Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation". The Journal of Biological Chemistry. 291 (1): 103–9. doi:10