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searching for ILC2 14 found (29 total)

alternate case: iLC2

RAR-related orphan receptor alpha (2,681 words) [view diff] exact match in snippet view article find links to article

role in the development of type 2 innate lymphoid cells (ILC2) and mutant animals are ILC2 deficient. In addition, although present in normal numbers

Fumio Takei (1,066 words) [view diff] exact match in snippet view article find links to article

ILC2s play a major role in allergen-induced lung inflammation by developing ILC2 deficient mice. More studies by his group showed other roles of ILC2s such

Interleukin 25 (2,281 words) [view diff] exact match in snippet view article find links to article

the activation of natural lymphoid cells 2 (ILC2). IL-25 and IL-33 are the most potent activators of ILC2. IL-25 induces the production of other cytokines

Immune dysregulation (2,440 words) [view diff] exact match in snippet view article find links to article

including the involvement of IgE, mast cells, Innate lymphoid cells 2 (ILC2), eosinophils, and basophils. Allergy symptoms are often related to the body's

TOX (1,814 words) [view diff] exact match in snippet view article find links to article

development of innate lymphoid cells. Innate lymphoid cells include ILC1, ILC2, ILC3 and NK cells. Notch signaling can aid in the development of all innate

Immune response (1,834 words) [view diff] exact match in snippet view article find links to article

IgG isotypes. Type 2 IR is caused by toxins and multicellular parasites. ILC2, epithelial cells, Th2 lymphocytes, eosinophils, basophils, mast cells, IgE

PRKCQ (2,407 words) [view diff] exact match in snippet view article find links to article

inflammation in effector T cells. PKC-θ plays a role in the activation of ILC2 and contribute to the proliferation of Th2 cells. The kinase PKC-θ is crucial

Interleukin 4 (2,293 words) [view diff] exact match in snippet view article find links to article

2015). "T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production"

Interleukin 13 (3,008 words) [view diff] exact match in snippet view article find links to article

2015). "T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production"

Tuft cell (1,840 words) [view diff] exact match in snippet view article find links to article

amplifies type-2 cytokine response, characterized by secretion of cytokines from ILC2 cells. Tissue remodeling during type-2 immune response is based on cytokine

Gabrielle Belz (1,492 words) [view diff] exact match in snippet view article find links to article

Neeson PJ, Belz GT. Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma. Nat Immunol. 2021 Jul;22(7):851-864

Trained immunity (2,543 words) [view diff] exact match in snippet view article find links to article

pro-inflammatory cytokine and antigen specificity are critical. Lung specific ILC2 showed memory-like phenotype after allergen exposure Trained immunity relies

Regulatory macrophages (1,836 words) [view diff] exact match in snippet view article find links to article

Mregs. Other cells such as eosinophils and innate lymphoid cells type 2 (ILC2) can promote M2 polarization by cytokine secretion. IL-9 can function as

Ana Domingos (2,568 words) [view diff] exact match in snippet view article find links to article

Ana I Domingos, Henrique Veiga-Fernandes. Neuro-mesenchymal units control ILC2 and Obesity via a brain–adipose circuit. Nature 597, 410–414 (2021). O'Brien