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searching for Histone methyltransferase 102 found (178 total)

alternate case: histone methyltransferase

PRC2 (558 words) [view diff] exact match in snippet view article find links to article

proteins is PRC1 (Polycomb Repressive Complex 1). This complex has histone methyltransferase activity and primarily methylates histone H3 on lysine 27 (i.e

KMT2A (2,275 words) [view diff] exact match in snippet view article find links to article

enzyme that in humans is encoded by the KMT2A gene. MLL1 is a histone methyltransferase deemed a positive global regulator of gene transcription. This

ASH2L (744 words) [view diff] exact match in snippet view article find links to article

Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene. ASH2L has been shown to interact with

NSD1 (300 words) [view diff] case mismatch in snippet view article find links to article

Protein 1) is a transcription coregulator protein that encodes Histone Methyltransferase and is associated with Sotos syndrome and Weaver syndrome. GRCh38:

SUZ12 (1,230 words) [view diff] exact match in snippet view article find links to article

Erdjument-Bromage H, Tempst P, Reinberg D (November 2002). "Histone methyltransferase activity associated with a human multiprotein complex containing

RBBP5 (864 words) [view diff] exact match in snippet view article find links to article

(Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Molecular

PRMT6 (602 words) [view diff] exact match in snippet view article find links to article

transferase activity histone methyltransferase activity protein-arginine omega-N monomethyltransferase activity histone methyltransferase activity (H4-R3 specific)

SETD7 (659 words) [view diff] exact match in snippet view article find links to article

et al. (2002). "Crystal structure and functional analysis of the histone methyltransferase SET7/9". Cell. 111 (1): 105–15. doi:10.1016/S0092-8674(02)00964-9

Polycomb protein EED (1,317 words) [view diff] exact match in snippet view article find links to article

Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D (2002). "Histone methyltransferase activity associated with a human multiprotein complex containing

IWS1 (609 words) [view diff] exact match in snippet view article find links to article

(PRMT5), is essential for cell survival. It also recruits a SET2 histone methyltransferase (Huntingtin-interacting protein HYPB, also known as SETD2) to

SETDB1 (1,452 words) [view diff] exact match in snippet view article find links to article

GJ, Chansky HA (2003). "An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors

Set domain containing 1b (353 words) [view diff] exact match in snippet view article find links to article

humans is encoded by the SETD1B gene. SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et

WDR5 (1,154 words) [view diff] exact match in snippet view article find links to article

(Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Mol. Cell

SMYD3 (840 words) [view diff] exact match in snippet view article find links to article

Iimura Y, Silva FP, Li M, et al. (August 2004). "SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells". Nature Cell Biology

SUV39H2 (556 words) [view diff] exact match in snippet view article find links to article

B, Kim IJ, et al. (2006). "Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer". Carcinogenesis. 27 (11): 2217–22

KMT2D (3,946 words) [view diff] exact match in snippet view article find links to article

for H3K4 methyltransferase activity in all mammalian Set1-like histone methyltransferase complexes. WDR5 binds directly with FYRN/FYRC domains of C-terminal

KMT2C (1,221 words) [view diff] exact match in snippet view article find links to article

methyltransferase activity transferase activity DNA binding protein binding histone methyltransferase activity (H3-K4 specific) metal ion binding acyltransferase activity

CXXC1 (714 words) [view diff] exact match in snippet view article find links to article

protein binding cis-regulatory region sequence-specific DNA binding histone methyltransferase activity (H3-K4 specific) metal ion binding unmethylated CpG binding

STAT5 (1,215 words) [view diff] exact match in snippet view article find links to article

STAT5 can also form homo-tetramers, usually in concert with the histone methyltransferase EZH2, and act as a transcriptional repressor. In the activation

WHSC1L1 (633 words) [view diff] exact match in snippet view article find links to article

Ponder, BA; Maehara, Y; Nakamura, Y; Hamamoto, R (Feb 2013). "The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved

KMT5B (828 words) [view diff] exact match in snippet view article find links to article

with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins". Cancer Biol. Ther. 5 (1): 65–70

Epiblast-derived stem cell (961 words) [view diff] exact match in snippet view article find links to article

state has also been achieved by suppressing the activity of the histone methyltransferase MLL1, also known as KMT2A. The inhibition of MLL1 via the small-molecule

WHSC1 (988 words) [view diff] exact match in snippet view article find links to article

transferase activity sequence-specific DNA binding DNA binding histone methyltransferase activity (H4-K20 specific) chromatin binding metal ion binding

Protein arginine methyltransferase 5 (1,408 words) [view diff] exact match in snippet view article find links to article

Molecular function methyltransferase activity transferase activity histone methyltransferase activity (H4-R3 specific) transcription corepressor activity methyl-CpG

Tapas Kumar Kundu (2,284 words) [view diff] exact match in snippet view article find links to article

of histone methyltransferase (HMTASE) and process of preparation thereof". compounds of structural formula I as site-specific inhibitors of histone methyltransferase

Tapas Kumar Kundu (2,284 words) [view diff] exact match in snippet view article find links to article

of histone methyltransferase (HMTASE) and process of preparation thereof". compounds of structural formula I as site-specific inhibitors of histone methyltransferase

Yasmin Hurd (2,257 words) [view diff] exact match in snippet view article find links to article

Stephen J.; Ren, Yanhua (2010-01-08). "Essential role of the histone methyltransferase G9a in cocaine-induced plasticity". Science. 327 (5962): 213–216

SIN3A (3,124 words) [view diff] exact match in snippet view article find links to article

Chansky HA (February 2003). "An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors

MLL4 (646 words) [view diff] exact match in snippet view article find links to article

binding protein binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K4 specific) DNA-binding transcription factor activity

Zinc finger protein 507 (73 words) [view diff] exact match in snippet view article find links to article

promoter sequence-specific DNA binding Cellular component nucleus histone methyltransferase complex Biological process regulation of transcription, DNA-templated

UTP18 (517 words) [view diff] exact match in snippet view article find links to article

et al. (2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Mol. Cell

ZNF451 (505 words) [view diff] exact match in snippet view article find links to article

sequence-specific DNA binding Cellular component PML body nucleus nucleoplasm histone methyltransferase complex Biological process negative regulation of transcription

Sotos syndrome (1,019 words) [view diff] exact match in snippet view article find links to article

syndrome. The NSD1 gene provides instructions for making a protein (histone methyltransferase) that is involved in normal growth and development. The function

SETD5 (258 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein binding histone methyltransferase activity (H3-K9 specific) methyltransferase activity transferase activity histone-lysine

MLLT10 (698 words) [view diff] exact match in snippet view article find links to article

R, Dubois G, Mazo A, Croce CM, Canaani E (2002). "ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional

Histone H4 (1,585 words) [view diff] exact match in snippet view article find links to article

studied. Studies have shown that H4R3 methylation by PRMT1 (a histone methyltransferase) appears to be essential in vivo for the establishment or maintenance

MEN1 (2,664 words) [view diff] exact match in snippet view article find links to article

(July 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Molecular

PRDM12 (1,814 words) [view diff] exact match in snippet view article find links to article

et al. (August 2005). "Characterization of the PR domain of RIZ1 histone methyltransferase". Biochemical and Biophysical Research Communications. 333 (3):

ZFP64 (449 words) [view diff] exact match in snippet view article find links to article

promoter sequence-specific DNA binding Cellular component nucleus histone methyltransferase complex Biological process regulation of transcription, DNA-templated

C21orf58 (1,729 words) [view diff] exact match in snippet view article find links to article

Antibody". genecards.org. Retrieved 2018-05-06. "Ash2l - Set1/Ash2 histone methyltransferase complex subunit ASH2 - Mus musculus (Mouse) - Ash2l gene & protein"

KDM4B (593 words) [view diff] exact match in snippet view article find links to article

methylated histone binding Cellular component nucleoplasm nucleus histone methyltransferase complex Biological process regulation of transcription, DNA-templated

KDM4D (410 words) [view diff] exact match in snippet view article find links to article

nucleoplasm site of double-strand break pericentric heterochromatin histone methyltransferase complex Biological process regulation of protein phosphorylation

ATF7IP (863 words) [view diff] exact match in snippet view article find links to article

Xuerun; Ma, Tingnan; Tong, Rongsheng; Zhong, Lei (2022). "Role of histone methyltransferase SETDB1 in regulation of tumourigenesis and immune response". Frontiers

POGZ (599 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm chromosome nucleus nucleoplasm cytosol histone methyltransferase complex Biological process kinetochore assembly cell cycle mitotic

SIN3B (1,106 words) [view diff] exact match in snippet view article find links to article

Chansky HA (Feb 2003). "An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors

KDM5C (855 words) [view diff] exact match in snippet view article find links to article

histone binding Cellular component nucleus nucleoplasm cytosol histone methyltransferase complex Biological process negative regulation of transcription

PAXIP1 (780 words) [view diff] exact match in snippet view article find links to article

Cellular component nuclear matrix nucleoplasm MLL3/4 complex nucleus histone methyltransferase complex chromosome Biological process response to ionizing radiation

PRMT2 (793 words) [view diff] exact match in snippet view article find links to article

Molecular function methyltransferase activity transferase activity histone methyltransferase activity protein homodimerization activity progesterone receptor

UTX (gene) (823 words) [view diff] exact match in snippet view article

sequence-specific DNA binding Cellular component nucleoplasm MLL3/4 complex histone methyltransferase complex nucleus Biological process respiratory system process

POLR2A (1,339 words) [view diff] exact match in snippet view article find links to article

FP, Li M, Yagyu R, Nakamura Y (August 2004). "SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells". Nat. Cell Biol

JARID1B (1,072 words) [view diff] exact match in snippet view article find links to article

histone binding Cellular component nucleoplasm nucleus cytosol histone methyltransferase complex Biological process response to fungicide positive regulation

KDM5D (1,083 words) [view diff] exact match in snippet view article find links to article

component nucleus nucleoplasm fibrillar center cellular component histone methyltransferase complex Biological process histone H3-K4 demethylation T cell

PAX7 (1,377 words) [view diff] exact match in snippet view article find links to article

with PAXBP1; the interaction links PAX7 to a WDR5-containing histone methyltransferase complex By similarity. Interacts with DAXX too. PAX7 functions

KDM4C (710 words) [view diff] exact match in snippet view article find links to article

Cellular component nucleus nucleoplasm pericentric heterochromatin histone methyltransferase complex Biological process regulation of transcription by RNA

NCOA6 (1,868 words) [view diff] exact match in snippet view article find links to article

organelle transcription regulator complex nucleoplasm nucleus histone methyltransferase complex cytosol Biological process myeloid cell differentiation

KDM5A (1,598 words) [view diff] exact match in snippet view article find links to article

holoenzyme complex nucleoplasm protein-DNA complex nucleolus nucleus histone methyltransferase complex Biological process male gonad development regulation of

Biphenotypic acute leukaemia (1,904 words) [view diff] exact match in snippet view article find links to article

gene encode Histone-lysine N-methyltransferase (HRX), which is a histone methyltransferase. It is a positive regulator for gene transcription. It has been

DNA (cytosine-5)-methyltransferase 3A (3,924 words) [view diff] exact match in snippet view article

"The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase". Nucleic Acids Research. 31 (9): 2305–2312. doi:10.1093/nar/gkg332

NOL5A (729 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function histone methyltransferase binding protein binding snoRNA binding RNA binding cadherin binding Cellular component cytoplasm

RBBP7 (1,452 words) [view diff] exact match in snippet view article find links to article

Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D (2002). "Histone methyltransferase activity associated with a human multiprotein complex containing

JARID2 (1,133 words) [view diff] exact match in snippet view article find links to article

activity Cellular component ESC/E(Z) complex nucleoplasm nucleus histone methyltransferase complex mitochondrion Biological process cell differentiation

Mir-26 microRNA precursor family (3,054 words) [view diff] exact match in snippet view article find links to article

Wong, CF.; Tellam, RL. (Apr 2008). "MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis". J Biol Chem. 283

PRDM9 (2,017 words) [view diff] exact match in snippet view article find links to article

regulatory region sequence-specific DNA binding chromatin DNA binding histone methyltransferase activity (H3-K4 specific) DNA-binding transcription factor activity

RNA polymerase II (3,100 words) [view diff] case mismatch in snippet view article find links to article

Scott; Yates, John R.; Workman, Jerry L. (2003-03-14). "The Set2 Histone Methyltransferase Functions through the Phosphorylated Carboxyl-terminal Domain

PPP1R8 (1,231 words) [view diff] exact match in snippet view article find links to article

in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2". J. Biol. Chem. 293 (47): 18031–18039. doi:10.1074/jbc.AC118

RE1-silencing transcription factor (2,022 words) [view diff] exact match in snippet view article find links to article

nucleoplasm transcription repressor complex nucleus cytoplasm histone methyltransferase complex Biological process cellular response to electrical stimulus

SETD6 (753 words) [view diff] exact match in snippet view article find links to article

methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling". Nature

TRIM28 (2,254 words) [view diff] exact match in snippet view article find links to article

viral chromatin and then recruits Mi2α and SETB1. SETB1 is a histone methyltransferase that recruits HP1, thus inducing heterochromatin formation. This

HDAC9 (2,396 words) [view diff] exact match in snippet view article find links to article

deacetylase complex transcription regulator complex nucleoplasm nucleus histone methyltransferase complex Biological process histone H3 deacetylation peptidyl-lysine

Antisense RNA (2,995 words) [view diff] exact match in snippet view article find links to article

b) AsRNAs can induce histone methylation by recruiting of a histone methyltransferase (HMT). 'Co-transcriptional regulation:' c) AsRNAs can cause RNA

Host cell factor C1 (1,794 words) [view diff] exact match in snippet view article find links to article

(Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Molecular

Osteosarcoma (3,791 words) [view diff] exact match in snippet view article find links to article

include TP53, RB1, PTEN, MYC, PIK3CA. In contrast, mutations in the histone methyltransferase gene SETD2 are rare in human osteosarcoma, but have been identified

Frank Gannon (1,395 words) [view diff] case mismatch in snippet view article find links to article

Windloch, K; Gannon, F; Lee, JS (2015). "Functional Role of G9a Histone Methyltransferase in Cancer". Front Immunol. 6: 487. doi:10.3389/fimmu.2015.00487

HIST1H3F (833 words) [view diff] exact match in snippet view article find links to article

et al. (2003). "Structure and catalytic mechanism of the human histone methyltransferase SET7/9" (PDF). Nature. 421 (6923): 652–6. Bibcode:2003Natur.421

AEBP2 (327 words) [view diff] exact match in snippet view article find links to article

Cao R, Zhang Y (July 2004). "SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex".

KDM4A (1,569 words) [view diff] exact match in snippet view article find links to article

center cytosol nucleus pericentric heterochromatin cytoplasm histone methyltransferase complex Biological process histone demethylation regulation of

Epigenetics (18,430 words) [view diff] exact match in snippet view article find links to article

differentiate into cardiac competent cells when treated with G9a histone methyltransferase inhibitor BIX01294. Cell plasticity, which is the adaptation of

Matthew Fuchter (1,380 words) [view diff] exact match in snippet view article find links to article

Mecheri, S.; Scherf, A.; Fuchter, M. J. (2012). "Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood

Epigenetic regulation of neurogenesis (5,725 words) [view diff] exact match in snippet view article find links to article

Specifically, deletion of a portion of the PRC2 complex, Ezh2, encoding histone methyltransferase, led to a twofold reduction of POU3F2/BRN2-expressing and SATB2-expressing

CBX1 (1,213 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function histone methyltransferase binding enzyme binding chromatin binding protein binding protein homodimerization activity

CBX5 (gene) (2,429 words) [view diff] exact match in snippet view article

nucleoplasm chromocenter heterochromatin chromosome, centromeric region histone methyltransferase complex transcription repressor complex chromosome PML body protein-containing

HSP90AB1 (3,113 words) [view diff] exact match in snippet view article find links to article

activity DNA polymerase binding disordered domain specific binding histone methyltransferase binding protein binding identical protein binding ubiquitin protein

Protein c-Fos (3,981 words) [view diff] exact match in snippet view article find links to article

presumably several other repressive proteins such as a repressive histone methyltransferase Nestler EJ (October 2008). "Transcriptional mechanisms of addiction:

CBX3 (1,284 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein domain specific binding histone methyltransferase binding protein binding identical protein binding enzyme binding

PRDM2 (1,243 words) [view diff] exact match in snippet view article find links to article

S2CID 20152972. Kim KC, Geng L, Huang S (Nov 2003). "Inactivation of a histone methyltransferase by mutations in human cancers". Cancer Research. 63 (22): 7619–23

HDAC1 (5,476 words) [view diff] exact match in snippet view article find links to article

Chansky HA (February 2003). "An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors

Nucleomodulin (1,450 words) [view diff] exact match in snippet view article find links to article

pneumophila, responsible for legionellosis, secretes an enzyme with histone methyltransferase activity capable of methylating histones at different chromosome

Nucleomodulin (1,450 words) [view diff] exact match in snippet view article find links to article

pneumophila, responsible for legionellosis, secretes an enzyme with histone methyltransferase activity capable of methylating histones at different chromosome

PRDM16 (1,680 words) [view diff] exact match in snippet view article find links to article

DNA-binding transcription factor activity, RNA polymerase II-specific histone methyltransferase activity (H3-K9 specific) methyltransferase activity transferase

Histone deacetylase 2 (4,587 words) [view diff] exact match in snippet view article find links to article

et al. (February 2003). "An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors

Behavioral epigenetics (8,159 words) [view diff] exact match in snippet view article find links to article

presumably several other repressive proteins such as a repressive histone methyltransferase Nestler EJ (October 2008). "Transcriptional mechanisms of addiction:

Inflammation (9,469 words) [view diff] exact match in snippet view article find links to article

methyltransferases (DNMTs), a histone deacetylase (SIRT1), and a histone methyltransferase (EZH2), and thus induce DNA methylation. DNA methylation of a

Eric J. Nestler (3,748 words) [view diff] exact match in snippet view article find links to article

Tarakovsky A, Schaefer A, Nestler EJ (2010). "Essential role of the histone methyltransferase G9a in cocaine-induced plasticity". Science. 327 (5962): 213–216

Epigenetics of cocaine addiction (3,823 words) [view diff] case mismatch in snippet view article find links to article

Schaefer, Anne, Nestler, Eric J. (2010). "Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity". Science. 327 (5962): 213–216

Retinoblastoma protein (9,499 words) [view diff] exact match in snippet view article find links to article

repression by the retinoblastoma protein through the recruitment of a histone methyltransferase". Molecular and Cellular Biology. 21 (19): 6484–94. doi:10.1128/MCB

Pharmacoepigenetics (4,224 words) [view diff] exact match in snippet view article find links to article

Another way to alter epigenetic modifications is through the use of histone methyltransferase inhibitors. Loss of function in genes encoding DNA demethylases

Zebrafish (11,535 words) [view diff] exact match in snippet view article find links to article

Bilodeau S, Orlando DA, Battisti V, et al. (March 2011). "The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its

MECOM (4,864 words) [view diff] exact match in snippet view article find links to article

polymerase II-specific DNA-binding transcription factor activity histone methyltransferase activity (H3-K9 specific) methyltransferase activity transferase

Heat shock protein 90kDa alpha (cytosolic), member A1 (8,175 words) [view diff] exact match in snippet view article

Silva FP, Li M, Yagyu R, Nakamura Y (Aug 2004). "SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells". Nature Cell Biology

Addiction-related structural neuroplasticity (3,976 words) [view diff] exact match in snippet view article find links to article

PMC 2677656. PMID 19295158. Maze, I. (2010). "Essential role of the histone methyltransferase G9a in cocaine-induced plasticity". Science. 327 (5962): 213–216

O-GlcNAc (12,376 words) [view diff] case mismatch in snippet view article find links to article

"O-GlcNAcylation Regulates the Stability and Enzymatic Activity of the Histone Methyltransferase EZH2". Proceedings of the National Academy of Sciences of the

Epigenetics of physical exercise (8,910 words) [view diff] no match in snippet view article find links to article

related to transcription repression. Mice deficient in a particular histone-methyltransferase gene, KMT2A (also known as MLL1), in adult excitatory neurons