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alternate case: histone demethylase
(Histone-H3)-lysine-36 demethylase
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JmjC domain-containing histone demethylase 1A, H3-K36-specific demethylase, histone-lysine (H3-K36) demethylase, histone demethylase, protein-6-N,6-N-dimethyl-L-lysineJARID1B (1,072 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 5B also known as histone demethylase JARID1B is a demethylase enzyme that in humans is encoded by the KDM5B gene. JARID1BKDM1A (2,086 words) [view diff] exact match in snippet view article find links to article
Lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a protein that in humans is encoded by the KDM1ADemethylase (3,087 words) [view diff] exact match in snippet view article find links to article
Buettner R (Dec 2006). "Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostateUTY (gene) (683 words) [view diff] exact match in snippet view article
Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene. This gene encodes a protein containing tetratricopeptide repeats whichKDM2B (1,477 words) [view diff] exact match in snippet view article find links to article
KDM2B protein has several domains including a JmjC domain that has a histone demethylase activity demethylating trimethylated Lys-4 and dimethylated Lys-36KDM1B (354 words) [view diff] exact match in snippet view article find links to article
Binda C, Mattevi A (Jun 2009). "A novel mammalian flavin-dependent histone demethylase". The Journal of Biological Chemistry. 284 (26): 17775–82. doi:10KDM7A (140 words) [view diff] exact match in snippet view article find links to article
Zhang T, Zhu Q, Zhang K, Jing N, Chen CD (2010). "Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4".KDM3A (229 words) [view diff] exact match in snippet view article find links to article
Eltzschig HK, Bührer C (August 2008). "Hypoxia upregulates the histone demethylase JMJD1A via HIF-1". Biochemical and Biophysical Research CommunicationsRCOR1 (1,128 words) [view diff] exact match in snippet view article find links to article
Matson C, Lan F, Iwase S, Baba T, Shi Y (2005). "Regulation of LSD1 histone demethylase activity by its associated factors". Mol. Cell. 19 (6): 857–64. doi:10KDM4A (1,569 words) [view diff] exact match in snippet view article find links to article
Ohlsson C, Poutanen M, Helin K (2017). "Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development". Development.KDM2A (956 words) [view diff] case mismatch in snippet view article find links to article
C, Zou T, Yao AY, Cooper MP, Boyartchuk V, Wang YX (2012). "The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis". PLOS Genetics. 8 (6):KDM6B (591 words) [view diff] exact match in snippet view article find links to article
(GSK-J1) has been developed to inhibit the jumonji domain of KDM6 histone demethylase family to modulate proinflammatory response in macrophages. MutationsKDM5A (1,598 words) [view diff] exact match in snippet view article find links to article
this gene. The Drosophila homolog, LID, was found to be an H3K4 histone demethylase that binds to c-Myc. It was recently renamed to Lysine DemethylaseLi Zhang (biologist) (946 words) [view diff] exact match in snippet view article
transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family; Heme: A versatile signaling molecule controllingBomedemstat (1,048 words) [view diff] exact match in snippet view article find links to article
associated with repression of DNA transcription. Identified as a histone demethylase in 2004, LSD1 demethylates H3K4me1 and H3K4me2 but not tri-methylatedKDM3B (650 words) [view diff] exact match in snippet view article find links to article
activity antioxidant activity dioxygenase activity metal ion binding histone demethylase activity transcription cis-regulatory region binding chromatin DNAPHF2 (205 words) [view diff] exact match in snippet view article find links to article
methylated histone binding protein binding oxidoreductase activity histone demethylase activity zinc ion binding Cellular component nucleoplasm chromosomeSHOX2 (696 words) [view diff] exact match in snippet view article find links to article
L (2009). "The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor". BMB Rep. 42KDM4D (410 words) [view diff] exact match in snippet view article find links to article
function oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity histone H3-methyl-lysine-9 demethylase activity DNA-bindingKDM4B (593 words) [view diff] exact match in snippet view article find links to article
function oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity histone H3-methyl-lysine-36 demethylase activity histoneKDM8 (161 words) [view diff] exact match in snippet view article find links to article
metal ion binding histone H3-methyl-lysine-36 demethylase activity histone demethylase activity protein binding peptidase activity hydrolase activity aminopeptidasePHF21A (554 words) [view diff] exact match in snippet view article find links to article
Matson C, Lan F, Iwase S, Baba T, Shi Y (2005). "Regulation of LSD1 histone demethylase activity by its associated factors". Mol. Cell. 19 (6): 857–64. doi:10Kabuki syndrome (3,368 words) [view diff] exact match in snippet view article find links to article
these genes code for a histone methyltransferase (KMT2D) and a histone demethylase (KDM6A), and play a part in the regulation of gene expression. UnderJMJD1C (267 words) [view diff] exact match in snippet view article find links to article
hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factorsRIOX2 (575 words) [view diff] exact match in snippet view article find links to article
function oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity identical protein binding histone H3-methyl-lysine-4 demethylaseARID5B (641 words) [view diff] exact match in snippet view article find links to article
DNA-binding transcription repressor activity, RNA polymerase II-specific histone demethylase activity DNA-binding transcription factor activity, RNA polymerasePHF8 (971 words) [view diff] exact match in snippet view article find links to article
activity histone H3-tri/di-methyl-lysine-27 demethylase activity histone demethylase activity zinc ion binding Cellular component nuclear membrane nucleoplasmKDM5C (855 words) [view diff] exact match in snippet view article find links to article
binding oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity zinc ion binding histone H3-methyl-lysine-4 demethylaseX-linked recessive inheritance (1,754 words) [view diff] exact match in snippet view article find links to article
intellectual disability and facial dysmorphism, caused by mutations in the histone demethylase PHF8 Simpson–Golabi–Behmel syndrome; coarse faces with protrudingCACUL1 (483 words) [view diff] exact match in snippet view article find links to article
regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1". FEBS Lett. 587 (1): 17–22. doi:10.1016/j.febslet.2012.10.054Vestigial-like family member 3 (422 words) [view diff] exact match in snippet view article find links to article
(March 2009). "The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor" (PDF). BMB ReportsSet domain containing 1b (353 words) [view diff] exact match in snippet view article find links to article
atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectualKDM4C (710 words) [view diff] exact match in snippet view article find links to article
dioxygenase activity metal ion binding chromatin binding enzyme binding histone demethylase activity androgen receptor binding zinc ion binding histone H3-methyl-lysine-36UTX (gene) (823 words) [view diff] exact match in snippet view article
binding histone H3-tri/di-methyl-lysine-27 demethylase activity histone demethylase activity chromatin binding sequence-specific DNA binding CellularChristopher J. Schofield (4,200 words) [view diff] exact match in snippet view article find links to article
Savitsky, Pavel; Gileadi, Opher (5 July 2007). "Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity". Nature. 448 (7149):Philip Kantoff (968 words) [view diff] exact match in snippet view article find links to article
inhibition controls aggressive prostate tumors deficient in Y-linked histone demethylase KDM5D". The Journal of Clinical Investigation. 128 (7): 2979–2995KDM5D (1,083 words) [view diff] exact match in snippet view article find links to article
binding oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity androgen receptor binding protein binding DNA-binding transcriptionYi Zhang (biochemist) (2,626 words) [view diff] exact match in snippet view article
Scott, Greg; Ray, Manas K.; Mishina, Yuji; Zhang, Yi (2007-11-01). "Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis"MiR-137 (2,115 words) [view diff] exact match in snippet view article find links to article
via miRecords database. Among these targets, LSD1 (Lysine-specific histone demethylase 1A, also known as KDM1A) has been shown to be directly downregulatedJMJD6 (1,276 words) [view diff] exact match in snippet view article find links to article
binding oxidoreductase activity peptidyl-lysine 5-dioxygenase activity histone demethylase activity signaling receptor activity transcription coactivator activityHOTAIR (1,244 words) [view diff] exact match in snippet view article find links to article
transcriptional silencing. The 3′ end of HOTAIR interacts with the histone demethylase LSD1. It is an important factor in the epigenetic differentiationJARID2 (1,133 words) [view diff] exact match in snippet view article find links to article
regulatory region sequence-specific DNA binding chromatin binding histone demethylase activity DNA-binding transcription repressor activity, RNA polymeraseCTBP2 (1,974 words) [view diff] exact match in snippet view article find links to article
then the histone methylase G9a can add methyl groups, while the histone demethylase lysine specific demethylase 1 (LSD1) can remove the activating markAkane Kawamura (463 words) [view diff] case mismatch in snippet view article find links to article
High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors". PLOS One. 5 (11): e15535. Bibcode:2010PLoSO...515535KH3K4me3 (2,323 words) [view diff] exact match in snippet view article find links to article
Clouaire T, Aguirrebengoa M, Legube G, Miller KM (July 2017). "Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNATranylcypromine (2,444 words) [view diff] exact match in snippet view article find links to article
serotonin release. Tranylcypromine has also been shown to inhibit the histone demethylase, BHC110/LSD1. Tranylcypromine inhibits this enzyme with an IC50 <Repressilator (2,190 words) [view diff] exact match in snippet view article find links to article
Evening-phased transcription factor CCA1 Hiking Expedition (CHE) and histone demethylase jumonji C domain-containing 5 (JMJD5) directly repress CCA1. OtherSónia Rocha (1,435 words) [view diff] exact match in snippet view article find links to article
Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG (2019). "Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate"Coiled-coil domain-containing 37 (FLJ40083) (820 words) [view diff] exact match in snippet view article
histone-lysine N-methyltransferase (SUV39H2), and lysine-specific histone demethylase 1A (KDM1A). In a study of the genes expressed in lung squamous cellEpigenetics in forensic science (1,686 words) [view diff] exact match in snippet view article find links to article
odontogenesis and quite a few affect the epigenome. For example, JMJD3 is a histone demethylase that modifies the methylation of homeobox and bone morphogeneticTemperature-dependent sex determination (3,823 words) [view diff] exact match in snippet view article find links to article
Yingjie; Cai, Cheng; Qian, Guoying; Capel, Blanche (2018-05-11). "The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtleSuccinic acid (4,290 words) [view diff] exact match in snippet view article find links to article
semialdehyde; PHD= prolyl hydroxylase; HIF-1a=hypoxia inducible factor 1a; TET= Ten-eleven Translocation Enzymes; JMJD3= Histone demethylase Jumonji D3H3K9me2 (2,601 words) [view diff] exact match in snippet view article find links to article
Chen J, Zhang J, Yang J, Xu L, Hu Q, Xu C, et al. (February 2017). "Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controlsHypoxia-inducible factor (4,911 words) [view diff] exact match in snippet view article find links to article
Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, et al. (March 2019). "Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate"FHL2 (5,030 words) [view diff] exact match in snippet view article find links to article
Buettner R (Dec 2006). "Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostateMothers against decapentaplegic homolog 3 (4,173 words) [view diff] exact match in snippet view article find links to article
S, Janknecht R (February 2008). "Repression of Smad3 activity by histone demethylase SMCX/JARID1C". Biochemical and Biophysical Research CommunicationsDNA oxidation (4,790 words) [view diff] exact match in snippet view article find links to article
promoter regions. Perillo et al., showed that the lysine-specific histone demethylase LSD1 generates a local burst of reactive oxygen species (ROS) thatTranscription (biology) (6,776 words) [view diff] exact match in snippet view article
(histone/nucleosome): Histone methylation/Histone methyltransferase EZH2 Histone demethylase Histone acetylation and deacetylation Histone deacetylase HDAC1 HistoneY chromosome (8,054 words) [view diff] exact match in snippet view article find links to article
inactivation. USP9Y USP9X Ubiquitin protease. DDX3Y DDX3X Helicase. UTY UTX Histone demethylase. TB4Y TB4X AZFb (none) Second AZF region on arm q. Prone to NAHRZebrafish (11,527 words) [view diff] exact match in snippet view article find links to article
PMID 17596452. Stewart S, Tsun ZY, Izpisua Belmonte JC (November 2009). "A histone demethylase is necessary for regeneration in zebrafish". Proceedings of the NationalEpigenetics of schizophrenia (5,482 words) [view diff] exact match in snippet view article find links to article
reelin transcripts in patients experiencing psychotic symptoms. HMT (histone demethylase) inhibitors also act on histones. They prevent the demethylationCancer epigenetics (12,530 words) [view diff] exact match in snippet view article find links to article
Similarly, expression of another epigenetic modifier, the LSD1 histone demethylase, is increased in chondrosarcoma, Ewing's sarcoma, osteosarcoma, andX-chromosome reactivation (5,094 words) [view diff] exact match in snippet view article find links to article
Crespin M, Ghariani SC, et al. (January 2012). "Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome". AmericanEpigenetics of neurodegenerative diseases (13,392 words) [view diff] exact match in snippet view article find links to article
inhibitors (HDACi), HAT modulators, DNA methyltransferase inhibitors, and histone demethylase inhibitors. The majority of epigenetic drugs tested for use against