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searching for H3K9me2 16 found (29 total)

alternate case: h3K9me2

Epigenetics of cocaine addiction (3,867 words) [view diff] exact match in snippet view article find links to article

on histone modification in the nucleus accumbens. They suggest that the H3K9me2 modification in this area of the brain plays a role in the stress and depression
FOSB (7,188 words) [view diff] exact match in snippet view article find links to article
to cocaine. This depends on ΔFosB inhibiting G9a gene expression, i.e. H3K9me2 synthesis which in turn inhibits transcription factors for ΔFosB. For this
SETD6 (741 words) [view diff] exact match in snippet view article find links to article
target genes by recruiting the PKMT G9a-like protein (GLP), which catalyzes H3K9me2 and leads to chromatin silencing and gene repression. In response to stimulation
Demethylase (3,087 words) [view diff] exact match in snippet view article find links to article
KDM4A, KDM4B and KDM4C demethylate H3K9me2/3, H3K9me3 and H3K36me2/3, and KDM4D, KDM4E and KDM4F demethylate H3K9me2/3. KDM4A, KDM4B, KDM4C and KDM4D have
Epigenetics of chronic pain (2,206 words) [view diff] exact match in snippet view article find links to article
sensitivity overall. There was an increase in G9a expression and its product H3K9me2 when a nerve injury occurred. A chromatin-immunoprecipitation assay showed
Toxoplasmosis (14,438 words) [view diff] exact match in snippet view article find links to article
2010; Sun et al., 2012a). Such drug-induced downregulation of G9a and H3K9me2 also sensitizes animals to the deleterious effects of subsequent chronic
Epigenetics of schizophrenia (5,482 words) [view diff] exact match in snippet view article find links to article
prominent example is the increased repressive methylation of histone 3 (H3K9me2), which has been associated with both age of disease onset and treatment
KDM3A (229 words) [view diff] exact match in snippet view article find links to article
transcript variants. KDM3A catalyzes the demethylation of H3K9me1 and H3K9me2 residues. Its function is dependent on the presence of cofactors Fe(II)
Addiction (31,267 words) [view diff] exact match in snippet view article find links to article
2010; Sun et al., 2012a). Such drug-induced downregulation of G9a and H3K9me2 also sensitizes animals to the deleterious effects of subsequent chronic
BHLHE41 (3,150 words) [view diff] exact match in snippet view article find links to article
methyltransferase G9a. G9a then catalyzes repressive histone 3 lysine 9 dimethylation (H3K9me2) at promoter sites of target genes of MyoD. G9a also methylates MyoD, which
Sexual addiction (7,780 words) [view diff] exact match in snippet view article find links to article
to cocaine. This depends on ΔFosB inhibiting G9a gene expression, i.e. H3K9me2 synthesis which in turn inhibits transcription factors for ΔFosB. For this
DNA oxidation (4,790 words) [view diff] exact match in snippet view article find links to article
Abbondanza C, Avvedimento EV (January 2008). "DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression". Science. 319 (5860):
Epigenetics (20,133 words) [view diff] exact match in snippet view article find links to article
to cocaine. This depends on ΔFosB inhibiting G9a gene expression, i.e. H3K9me2 synthesis which in turn inhibits transcription factors for ΔFosB. For this
Thomas Jenuwein (2,081 words) [view diff] exact match in snippet view article find links to article
Mechtler K, Kowalski JR, Hamon CA, Kelly TA, Jenuwein T (2007). "Reversal of H3K9me2 by a small molecule inhibitor for the G9a histone methyltransferase". Molecular
Reward system (13,122 words) [view diff] exact match in snippet view article find links to article
to cocaine. This depends on ΔFosB inhibiting G9a gene expression, i.e. H3K9me2 synthesis which in turn inhibits transcription factors for ΔFosB. For this
CCDC190 (2,085 words) [view diff] exact match in snippet view article find links to article
the microarray data on GEO database of NCBI, it can be found that the H3K9me2 methyltransferase G9a depletion can increase the expression amount of c1orf110