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searching for Gating (electrophysiology) 74 found (83 total)

alternate case: gating (electrophysiology)

Cys-loop receptor (907 words) [view diff] no match in snippet view article find links to article

channels are activated through allosteric interactions between the binding and gating domains. Once the agonist binds it brings about conformational changes (including

SK channel (2,730 words) [view diff] no match in snippet view article find links to article

(Intermediate conductance) due to its higher conductance 20 – 80 pS. The SK channel gating mechanism is controlled by intracellular calcium levels. Calcium enters

Voltage-gated potassium channel (1,770 words) [view diff] no match in snippet view article find links to article

transmembrane field and contribute to the gating charge. The position of these arginines, known as gating arginines, are highly conserved in all voltage-gated

HCN channel (1,554 words) [view diff] no match in snippet view article find links to article

kinetics, and a lower sensitivity to cAMP, while HCN4 channels are slowly gating and strongly sensitive to cAMP. HCN2 and HCN3 have intermediate properties

L-type calcium channel (2,004 words) [view diff] no match in snippet view article find links to article

channels, situated in the T-tubules. Muscle depolarization results in large gating currents, but anomalously low calcium flux, which is now explained by the

Sodium channel (5,591 words) [view diff] no match in snippet view article find links to article

channel – Ion channel complex through which calcium ions pass Chronaxie – Electrophysiology metric Epithelial sodium channel – Group of membrane proteins Ion

Voltage-gated ion channel (2,290 words) [view diff] no match in snippet view article find links to article

the membrane. It is thought that the first 4 arginines account for the gating current, moving toward the extracellular solvent upon channel activation

Acid-sensing ion channel (2,777 words) [view diff] no match in snippet view article find links to article

protein interactions and modulations, ion permeability, and gating. However, the gating and mechanics of each acid-sensing ion channel is determined

R-type calcium channel (1,325 words) [view diff] no match in snippet view article find links to article

2007). "The role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels". The Journal of Biological Chemistry. 282 (38): 27944–52

Calcium channel (759 words) [view diff] no match in snippet view article find links to article

affecting downstream signaling pathways. The following tables explain gating, gene, location and function of different types of calcium channels, both

Q-type calcium channel (81 words) [view diff] no match in snippet view article find links to article

By gating mechanism

Synthetic ion channels (3,025 words) [view diff] no match in snippet view article find links to article

usually required. Sophisticated experiments intended to probe selectivity, gating, and other channel parameters have been developed over the past two decades

Hodgkin–Huxley model (2,883 words) [view diff] no match in snippet view article find links to article

Anastassiou, Costas A. (2022-08-09). "Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types". Cell

KvLQT1 (1,503 words) [view diff] no match in snippet view article find links to article

Gerwert K, Attali B, Seebohm G (2011). "Structural basis of slow activation gating in the cardiac I Ks channel complex". Cellular Physiology and Biochemistry

HCN4 (1,313 words) [view diff] no match in snippet view article find links to article

Lichter P, Kaupp UB (Aug 1999). "Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus

Bueno-Orovio–Cherry–Fenton model (3,470 words) [view diff] no match in snippet view article find links to article

transmembrane potential, and three ODEs that define the evolution of the so-called gating variables, i.e. probability density functions whose aim is to model the

N-type calcium channel (2,011 words) [view diff] no match in snippet view article find links to article

"Alternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channels". The Journal of Physiology. 576 (Pt 1): 119–34

BK channel (3,715 words) [view diff] no match in snippet view article find links to article

(β1-4), each of which have different expression patterns that modify the gating properties of the BK channel. The β1 subunit is primarily responsible for

IK channel (305 words) [view diff] no match in snippet view article find links to article

explains why this process has a Hill coefficient of 4. This Ca2+–induced gating process resembles that which has been described for the small-conductance

Pacemaker current (1,195 words) [view diff] no match in snippet view article find links to article

pacemaker current: from basics to the clinics". Journal of Cardiovascular Electrophysiology. 18 (3): 342–7. doi:10.1111/j.1540-8167.2006.00736.x. PMID 17284289

Voltage-gated calcium channel (3,092 words) [view diff] no match in snippet view article find links to article

the associated subunits have several functions including modulation of gating. There are several different kinds of high-voltage-gated calcium channels

G protein-gated ion channel (3,706 words) [view diff] no match in snippet view article find links to article

allowing direct gating of calcium channels by G proteins to produce effects more quickly than the cAMP cascade could. This direct gating has also been found

SCN5A (2,996 words) [view diff] no match in snippet view article find links to article

abnormalities--one group of diseases, many genes". Journal of Cardiovascular Electrophysiology. 17 (4): 446–55. doi:10.1111/j.1540-8167.2006.00427.x. PMID 16643374

Cation channels of sperm (823 words) [view diff] no match in snippet view article find links to article

By gating mechanism

Channelome (522 words) [view diff] no match in snippet view article find links to article

can be performed by a variety of techniques, including patch clamp electrophysiology, PCR, and immunohistochemistry. Channelomics is being used to screen

Nav1.4 (1,578 words) [view diff] no match in snippet view article find links to article

By gating mechanism

Refractory period (physiology) (1,302 words) [view diff] no match in snippet view article

of potassium channels in closing. Voltage-gated sodium channels have two gating mechanisms, the activation mechanism that opens the channel with depolarization

Voltage clamp (3,681 words) [view diff] no match in snippet view article find links to article

model the action potential in detail has laid the foundation for electrophysiology; for which they shared the 1963 Nobel Prize in Physiology or Medicine

KCNE3 (3,185 words) [view diff] no match in snippet view article find links to article

for permitting ultrarapid firing of neurons because of the extremely fast gating (activation and deactivation). KCNE3 moderately slows Kv3.1 and Kv3.2 activation

Afterhyperpolarization (611 words) [view diff] no match in snippet view article find links to article

phosphatidylinositol 4,5-bisphosphate in the expression, regulation, and gating of the slow afterhyperpolarization current in the cerebral cortex, Frontiers

Current–voltage characteristic (1,162 words) [view diff] no match in snippet view article find links to article

field of biological electricity, particularly in the sub-field of electrophysiology. In this case, the voltage refers to the voltage across a biological

CHRNA1 (1,174 words) [view diff] no match in snippet view article find links to article

encodes an alpha subunit that plays a role in acetylcholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have

Inward-rectifier potassium channel (2,007 words) [view diff] no match in snippet view article find links to article

By gating mechanism

Genetically encoded voltage indicator (3,013 words) [view diff] no match in snippet view article find links to article

allows for spike detection fidelity comparable to electrode-based electrophysiology but without the invasiveness. Researchers have used it to probe neural

Chronaxie (2,365 words) [view diff] no match in snippet view article find links to article

complex models of the excitable membrane, which take into account ion-channel gating mechanisms, as well as intracellular current flow, which may be the main

Repolarization (2,413 words) [view diff] no match in snippet view article find links to article

Borhani DW, Leffler AE, Dror RO, Shaw DE (April 2012). "Mechanism of voltage gating in potassium channels". Science. 336 (6078): 229–33. Bibcode:2012Sci...336

Voltage-gated sodium channel (3,587 words) [view diff] no match in snippet view article find links to article

channels are treated as a population that are affected by three independent gating variables. Each of these variables can attain a value between 1 (fully permeant

Epithelial sodium channel (2,827 words) [view diff] no match in snippet view article find links to article

By gating mechanism

Exponential integrate-and-fire (1,369 words) [view diff] no match in snippet view article find links to article

x0(V){\displaystyle x_{0}(V)} is a saturating nonlinearity, similar to the gating variable m of the Hodgkin-Huxley model. The term b[Ex−V]x{\displaystyle

Mechanosensitive channels (7,817 words) [view diff] no match in snippet view article find links to article

cells, blood pressure in veins and arteries, micturition, and heart electrophysiology and contractility. In addition to these functionalities, stretch-activated

SCN3B (1,006 words) [view diff] no match in snippet view article find links to article

subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics". Proc Natl Acad Sci U S A. 97 (5): 2308–13. Bibcode:2000PNAS

Joseph Randall Moorman (1,429 words) [view diff] no match in snippet view article find links to article

post-doctoral research training in membrane biophysics and molecular electrophysiology at Baylor University. From 1985-1990, Moorman was Assistant Professor

TRPA1 (3,998 words) [view diff] no match in snippet view article find links to article

domain. Breakthrough research combining cryo-electron microscopy and electrophysiology later elucidated the molecular mechanism of how the channel functions

Low-threshold spikes (2,150 words) [view diff] no match in snippet view article find links to article

in response to change in membrane potential, and the voltage-dependent gating of the T-type calcium channels. Latency is decreased with an increased depolarizing

Ball and chain inactivation (2,508 words) [view diff] no match in snippet view article find links to article

Armstrong CM & Bezanilla, F (1977). "Inactivation of the sodium channel. II. Gating current experiments". The Journal of General Physiology. 70 (5). Rockefeller

P2RX4 (2,944 words) [view diff] no match in snippet view article find links to article

the desensitized receptor no longer exhibit the cytoplasmic cap. Electrophysiology studies have revealed differences in the rates of receptor desensitization

ROMK (1,756 words) [view diff] no match in snippet view article find links to article

term "inwardly rectifying" referring to corresponding currents in electrophysiology, but has limited physiological relevance). ROMK was identified as

Cell physiology (857 words) [view diff] no match in snippet view article find links to article

U.S. National Library of Medicine Medical Subject Headings (MeSH) Electrophysiology at the U.S. National Library of Medicine Medical Subject Headings

KCNE5 (1,859 words) [view diff] no match in snippet view article find links to article

idiopathic ventricular fibrillation". Circulation: Arrhythmia and Electrophysiology. 4 (3): 352–61. doi:10.1161/CIRCEP.110.959619. PMID 21493962. Palmer

Kv1.1 (2,127 words) [view diff] no match in snippet view article find links to article

in the ion-conducting pore of the channel. This was determined by electrophysiology analysis. The length of time the membrane is depolarised is decreased

N100 (3,568 words) [view diff] no match in snippet view article find links to article

stimuli. With paired clicks, the second N100 is reduced due to sensory gating. The difference between many consonants is their voice onset time (VOT)

Forward problem of electrocardiology (4,648 words) [view diff] no match in snippet view article find links to article

I_{\text{ion}}} is the ionic current, which depends also from a so-called gating variable w{\displaystyle w} (accounting for cellular-level ionic behavior)

Dario DiFrancesco (2,620 words) [view diff] no match in snippet view article find links to article

DiFrancesco published several studies demonstrating its permeability and gating characteristics, its involvement in the autonomic rate control, and investigated

Optogenetics (11,915 words) [view diff] no match in snippet view article find links to article

genetically labelled neurons with light and by using imaging and electrophysiology techniques to record the activity of other cells, researchers can

Outline of cardiology (7,304 words) [view diff] no match in snippet view article find links to article

coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in cardiology are called cardiologists

Electroencephalography (15,276 words) [view diff] no match in snippet view article find links to article

(November 2006). "Gamma and beta neural activity evoked during a sensory gating paradigm: effects of auditory, somatosensory and cross-modal stimulation"

Supraventricular tachycardia (3,431 words) [view diff] no match in snippet view article find links to article

against excessively high rates arising from the supraventricular areas by a "gating mechanism" at the atrioventricular node, which allows only a proportion

Basal ganglia (6,289 words) [view diff] no match in snippet view article find links to article

to reward. There is also evidence from non-human primate and human electrophysiology studies that other basal ganglia structures including the globus pallidus

Hertz Foundation (1,984 words) [view diff] no match in snippet view article find links to article

High Speed Polycrystalline Silicon Photoconductors for On-Chip Pulsing and Gating 1987 Brian L. Heffner, Switchable Optical Fiber Taps Using the Acousto-Optic

Magnetoencephalography (5,053 words) [view diff] no match in snippet view article find links to article

the data difficult. Auditory evoked field Direct brain interfaces Electrophysiology Evoked field FieldTrip Magnetocardiography Magnetogastrography Magnetometer

Visual processing (2,052 words) [view diff] no match in snippet view article find links to article

fields and the global context of a scene. Two other monkey study used electrophysiology to find different frequencies that are associated with feedforward

Endophenotype (2,218 words) [view diff] no match in snippet view article find links to article

psychosis, but the underlying phenotypes are, for example, a lack of sensory gating and a decline in working memory. Both of these traits have a clear genetic

Index of biochemistry articles (2,471 words) [view diff] no match in snippet view article find links to article

electron volt - electronegativity - electrophile - electrophoresis - electrophysiology - element - element symbol - ELISA - ELISPOT - embryo - embryonal

KCNE2 (3,521 words) [view diff] no match in snippet view article find links to article

is associated with sinus bradycardia". Journal of Cardiovascular Electrophysiology. 24 (9): 1021–7. doi:10.1111/jce.12163. PMC 4059362. PMID 23631727

D. James Surmeier (2,529 words) [view diff] no match in snippet view article find links to article

at-risk in Parkinson's disease. Using a combination of patch clamp electrophysiology and two photon laser scanning microscopy to monitor key intracellular

Visual N1 (3,531 words) [view diff] no match in snippet view article find links to article

Evoked field Evoked potential International Society for Clinical Electrophysiology of Vision Late positive component Lateralized readiness potential

Computational neuroscience (4,522 words) [view diff] no match in snippet view article find links to article

simulation Computational anatomy Connectomics Differentiable programming Electrophysiology FitzHugh–Nagumo model Galves–Löcherbach model Goldman equation Hodgkin–Huxley

Georg Winterer (1,774 words) [view diff] no match in snippet view article find links to article

publications are dedicated to addiction research and schizophrenia (electrophysiology, neuroimaging, pharmacology, genetics). His more recent scientific

Uniporter (3,212 words) [view diff] no match in snippet view article find links to article

research is focusing on techniques using recombinant DNA technology, electrophysiology and advanced imaging to understand uniporter functions. These experiments

Neuron (8,964 words) [view diff] no match in snippet view article find links to article

done by considering the three essential qualities of all neurons: electrophysiology, morphology, and the individual transcriptome of the cells. Besides

Lysenin (2,898 words) [view diff] no match in snippet view article find links to article

on prepore to pore transition was given by congestion effects in electrophysiology experiments. High-Speed AFM studies incubating lysenin on sphingomyelin/cholesterol

Theories of general anaesthetic action (6,745 words) [view diff] no match in snippet view article find links to article

changes in proteins that may be the basis for such membrane events as ion gating, synaptic transmitter release, and transmitter binding to receptors. More

Magnesium transporter (12,021 words) [view diff] no match in snippet view article find links to article

Maguire ME, Ito K, Maturana A, Nureki O (Nov 2009). "Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis". The EMBO Journal

Cluster of Excellence Frankfurt Macromolecular Complexes (15,450 words) [view diff] no match in snippet view article find links to article

protonation changes in channelrhodopsin-2 and their relevance to channel gating". Proc Natl Acad Sci USA. 110 (14): E1273-81. Bibcode:2013PNAS..110E1273L