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Longer titles found: Diastereomeric recrystallization (view)

searching for Diastereomer 40 found (102 total)

3,4-Dichloromethylphenidate (479 words) [view diff] exact match in snippet view article find links to article

remove those monoamines from the synaptic cleft. 3,4-DCMP, the threo-diastereomer, is approximately seven times more potent than methylphenidate in animal

Isoborneol (224 words) [view diff] exact match in snippet view article find links to article

hydroxyl group in this compound is placed in an exo position. The endo diastereomer is called borneol. Being chiral, isoborneol exists as enantiomers. Isoborneol

Conia-ene reaction (1,805 words) [view diff] exact match in snippet view article find links to article

AuCl(PPh3) and AgBF4 to furnish vinyl iodide 3 in high yield as a single diastereomer. The remainder of the molecule was completed in three steps to give (+)-lycopladine

Reductions with hydrosilanes (1,452 words) [view diff] exact match in snippet view article find links to article

either diastereomer of 2-phenyl-2-norbornanol leads exclusively to the endo diastereomer of 2-phenylnorbornane. None of the exo diastereomer was observed

Rubottom oxidation (3,396 words) [view diff] exact match in snippet view article find links to article

compound that could then be carried on to (±)-periplanone B and its diastereomers to prove its structure. Brevisamide, a proposed biosynthetic precursor

Nitrone-olefin (3+2) cycloaddition (923 words) [view diff] exact match in snippet view article

between the alkene and nitrone often leads to the generation of a single diastereomer of product. In this example, the bulkier phenyl substituent ends up on

Α-Tocopherol (564 words) [view diff] exact match in snippet view article find links to article

because whether l-α-tocopherol should mean SSS enantiomer or the SRR diastereomer is not clear, from historical reasons. The SRR may be named 2-epi-α-tocopherol

Trigonal bipyramidal molecular geometry (683 words) [view diff] exact match in snippet view article find links to article

Pseudorotation is similar in concept to the movement of a conformational diastereomer, though no full revolutions are completed. In the process of pseudorotation

Organoindium chemistry (1,134 words) [view diff] exact match in snippet view article find links to article

present in an α-oxy aldehyde, the product is expected to be the syn diastereomer. A sample reaction of chelation versus non-chelation control is illustrated

C4H10O4 (66 words) [view diff] exact match in snippet view article find links to article

(or polyol) food additive Threitol, a four-carbon sugar alcohol; the diastereomer of erythritol This set index page lists chemical structure articles associated

1,2-Diaminopropane (277 words) [view diff] exact match in snippet view article find links to article

diastereomeric tartaric acid ammonium salt. After purification of the diastereomer, the diamine can be regenerated by treatment of the ammonium salt with

Carboprost (597 words) [view diff] exact match in snippet view article find links to article

transformations, including separation of diastereomers, so that the final product is the C-15 analogue. This diastereomer is reputably freeer of prostaglandin

Diphenylethylenediamine (340 words) [view diff] exact match in snippet view article find links to article

two enantiomers S,S- and R,R-. The chiral diastereomers are used in asymmetric hydrogenation. Both diastereomers are bidentate ligands. 1,2-Diphenyl-1,2-ethylenediamine

W. Clark Still (2,031 words) [view diff] exact match in snippet view article find links to article

chlorotrimethylsilane to form the macrocyclic silyl enol ether as a single diastereomer. This intermediate was then transformed into a key enone substrate over

Johnson–Corey–Chaykovsky reaction (2,122 words) [view diff] exact match in snippet view article find links to article

availability of only one enantiomer of the reagent. The synthesis of the axial diastereomer is rationalized via the 1,3-anomeric effect which reduces the nucleophilicity

Organostannane addition (971 words) [view diff] exact match in snippet view article find links to article

allylstannanes often react with good stereoselectivity to give single diastereomers. Models explaining the sense of selectivity are reliable. In terms of

Petasis reaction (3,232 words) [view diff] exact match in snippet view article find links to article

room temperature, the corresponding allylamine is formed as a single diastereomer. Furthermore, enantiomeric purity can be achieved by hydrogenation of

Erythritol (2,283 words) [view diff] exact match in snippet view article find links to article

for erythritol. Erythritol tetranitrate Pentaerythritol Threitol, the diastereomer of erythritol O'Neil M, ed. (2006). The Merck Index: An Encyclopedia

Paraldehyde (1,458 words) [view diff] exact match in snippet view article find links to article

produced and used as a mixture of two diastereomers, known as cis- and trans-paraldehyde. For each diastereomer, two chair conformers are possible. The

Fosfomycin (2,278 words) [view diff] exact match in snippet view article find links to article

(2011). "Asymmetric synthesis of (−)-fosfomycin and its trans-(1S,2S)-diastereomer using a biocatalytic reduction as the key step". Tetrahedron: Asymmetry

Hammond's postulate (2,552 words) [view diff] exact match in snippet view article find links to article

energy-inequivalent intermediates, referred to as diastereomers. According to Hammond's postulate, the more stable diastereomer is formed faster. Elimination, bimolecular

Pauson–Khand reaction (2,913 words) [view diff] exact match in snippet view article find links to article

temperature and ultrasound failed to improve the d.r. for the desired diastereomer (the red hydrogen). But the N-oxide additive, while lower yielding, gave

Tartaric acid (2,286 words) [view diff] exact match in snippet view article find links to article

enantiomer as (2S,3S)-tartaric acid (D-(-)-tartaric acid). The meso diastereomer is referred to as (2R,3S)-tartaric acid or (2S,3R)-tartaric acid. Dextro

Pharmacology of antidepressants (2,911 words) [view diff] exact match in snippet view article find links to article

faeces (20–30%) CYP3A4 ? Reboxetine 94% 12–13 26 L (R,R diastereomer), 63 L (S,S diastereomer) ? 2 hr 97% Urine (78%; 10% as unchanged) CYP3A4 ? Trazodone

Ephedrine (4,412 words) [view diff] exact match in snippet view article find links to article

wrongly named L-ephedrine and the dextrorotary d-pseudoephedrine (the diastereomer) wrongly D-pseudoephedrine. The IUPAC names of the two enantiomers are

Intramolecular reactions of diazocarbonyl compounds (1,217 words) [view diff] exact match in snippet view article find links to article

is applied in a racemic synthesis of sirenin. A single cyclopropane diastereomer was isolated in 55% yield after diazoketone formation and cyclization

Broad-spectrum chemokine inhibitor (1,706 words) [view diff] exact match in snippet view article find links to article

synthetic peptide, NR58-3.14.3, in serum by LC-MS with inclusion of a diastereomer as internal standard". Anal. Biochem. 278 (1): 14–21. doi:10.1006/abio

George S. Hammond (3,775 words) [view diff] exact match in snippet view article find links to article

energy-inequivalent intermediates, referred to as diastereomers. According to Hammond's postulate, the more stable diastereomer is formed faster. Elimination, bimolecular

KCNA3 (4,363 words) [view diff] exact match in snippet view article find links to article

I, Chi V, Chandy KG, Pennington MW, Norton RS (January 2008). "The D-diastereomer of ShK toxin selectively blocks voltage-gated K + channels and inhibits

Elias James Corey (5,524 words) [view diff] exact match in snippet view article find links to article

in the prostaglandin synthesis revealing a 9:1 mixture of the desired diastereomer (scheme 24). The iodolactonization transform affords an allylic alcohol

Alloisoleucine (202 words) [view diff] exact match in snippet view article find links to article

amino acid (BCAA). It is the rarest of the four. L-Alloisoleucine is a diastereomer of the proteogenic amino acid L-isoleucine. The stereochemistry of the

Κ-opioid receptor (7,675 words) [view diff] exact match in snippet view article find links to article

optically pure enantiomers of the kappa opioid agonist, U50,488, and its cis diastereomer: evidence for three kappa receptor subtypes" (PDF). European Journal

Discovery and development of ACE inhibitors (3,407 words) [view diff] exact match in snippet view article find links to article

with the initial modeling studies of RXPA380 which showed that only one diastereomer could accommodate in the active site of germinal ACE. Analogues where

W. Dean Harman (835 words) [view diff] exact match in snippet view article find links to article

suggested that dihapto-coordinate complex can be isolated as a single diastereomer, methylated, and reacted with a number of nucleophiles. In 2017, he reviewed

Lewis acid catalysis (5,017 words) [view diff] exact match in snippet view article find links to article

2-addition, proposed by Kumada, is presented in the scheme below; the syn diastereomer is predominant when the (E) silane is used, and also slightly favored

Ugi's amine (1,790 words) [view diff] exact match in snippet view article find links to article

allowing broad synthetic utility of Ugi’s amine. If the (S,Sp) or (R,Rp) diastereomers are desired, the first metalate can be trapped with TMSCl to block the

Cyclopentadienylcobalt dinitrosyl (3,688 words) [view diff] exact match in snippet view article find links to article

functionalized alkane. Most functionalizations were highly selective for the diastereomer which had the Michael acceptor in the endo position. Additionally most

Spirotetronate cyclase AbyU (1,045 words) [view diff] exact match in snippet view article find links to article

Li, Qinglian; Ju, Jianhua (July 7, 2021). "Enzymatic Synthesis of a Diastereomer of Neoabyssomicin Derivative Using the Diels‐Alderase AbyU". Chinese

Totarol (4,785 words) [view diff] exact match in snippet view article find links to article

treated with SmI2 to yield totarane diastereomers which were separated by column chromatography. The desired diastereomer was treated with p-TsOH in benzene

Chiral analysis (6,792 words) [view diff] exact match in snippet view article find links to article

derivatives using enantiomerically pure chiral derivatizing agent. The diastereomers thus formed unlike enantiomers, exhibit different physicochemical properties