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Longer titles found: DNA methylation in cancer (view), RNA-directed DNA methylation (view), Decrease in DNA Methylation I (DDM1) (view)

searching for DNA methylation 304 found (753 total)

alternate case: dNA methylation

RNA polymerase V (177 words) [view diff] exact match in snippet view article find links to article

small interfering RNA (siRNA). Pol V is involved in siRNA-directed DNA methylation pathway which leads to heterochromatic silencing. RNA polymerase V
DNA (cytosine-5)-methyltransferase 3A (2,719 words) [view diff] exact match in snippet view article
process called DNA methylation. The enzyme is encoded in humans by the DNMT3A gene. This enzyme is responsible for de novo DNA methylation. Such function
Howard Cedar (329 words) [view diff] exact match in snippet view article find links to article
born January 12, 1943) is an Israeli American biochemist who works on DNA methylation, a mechanism that turns genes on and off. Howard Chaim Cedar was born
Computational epigenetics (1,204 words) [view diff] exact match in snippet view article find links to article
Contains DNA methylation data of human chromosomes 21, 22, male germ cells and DNA methylation profiles in monozygotic and dizygotic twins. MethyLogiX DNA methylation
Epigenetics of schizophrenia (2,858 words) [view diff] exact match in snippet view article find links to article
both of these changes are linked to schizophrenia and its symptoms. DNA methylation is the covalent addition of a methyl group to a segment of the DNA
RNA polymerase IV (374 words) [view diff] exact match in snippet view article find links to article
against the invading viruses and transposable elements by RNA directed DNA methylation. Polymerase IV and ROS1 demethylase unlocks and recondenses the 5S
5-Methylcytosine (2,539 words) [view diff] exact match in snippet view article find links to article
between chronological age and levels of DNA methylation in the genome. Coupling the levels of DNA methylation, in specific sets of CpGs called "clock
DNMT3B (1,415 words) [view diff] exact match in snippet view article find links to article
X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase
Bayesian tool for methylation analysis (1,093 words) [view diff] exact match in snippet view article find links to article
DNA immunoprecipitation) is an experimental technique used to assess DNA methylation levels by using an antibody to isolate methylated DNA sequences. The
Methyltransferase (2,884 words) [view diff] exact match in snippet view article find links to article
function of Retinoblastoma protein N-terminal methylation is not known. DNA methylation, a key component of genetic regulation, occurs primarily at the 5-carbon
Human Epigenome Project (224 words) [view diff] exact match in snippet view article find links to article
with the stated aim to "identify, catalog, and interpret genome-wide DNA methylation patterns of all human genes in all major tissues". It is financed by
DNMT3L (1,056 words) [view diff] exact match in snippet view article find links to article
X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear
Epigenetic therapy (2,643 words) [view diff] exact match in snippet view article find links to article
The first is DNA methylation, where a cytosine residue that is followed by a guanine residue (CpG) is methylated. In general, DNA methylation attracts proteins
HELLS (825 words) [view diff] exact match in snippet view article find links to article
the HELLS gene. The HELLS gene has proved to play critical roles in DNA methylation, chromatin packaging, control of Hox genes, stem cell proliferation
Epigenetics (journal) (156 words) [view diff] case mismatch in snippet view article
It is the official journal of the Epigenetics Society (formerly the DNA Methylation Society). The editor-in-chief is Manel Esteller (University of Barcelona)
Tuberculinic acid (431 words) [view diff] exact match in snippet view article find links to article
most toxic component of the bacillus. It was from this compound that DNA methylation was discovered as it was the first molecule found to contain 5-methylcytosine
Immunofluorescence (1,976 words) [view diff] exact match in snippet view article find links to article
method to gain insight into the levels and localization patterns of DNA methylation since it is a more time-consuming method than true quantitative methods
8-Oxo-2'-deoxyguanosine (2,551 words) [view diff] exact match in snippet view article find links to article
promoter region of a gene, can repress expression of the gene (see DNA methylation). In general, epigenetic alteration can modulate gene expression. As
Downregulation and upregulation (1,767 words) [view diff] exact match in snippet view article find links to article
strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island". PLOS Genet. 4 (8): e1000155.
Methyl-CpG-binding domain (561 words) [view diff] exact match in snippet view article find links to article
could protect a 12 nucleotide region surrounding a methyl CpG pair. DNA methylation at CpG dinucleotides, the most common DNA modification in eukaryotes
Robin Holliday (667 words) [view diff] exact match in snippet view article find links to article
BioMolecular Engineering, Sydney, Australia. In 1975 he suggested that DNA methylation could be an important mechanism for the control of gene expression
MBD3 (1,442 words) [view diff] exact match in snippet view article find links to article
protein 3 is a protein that in humans is encoded by the MBD3 gene. DNA methylation is the major modification of eukaryotic genomes and plays an essential
Somatic epitype (219 words) [view diff] exact match in snippet view article find links to article
sequence. Physically, the somatic epitype corresponds to changes in DNA methylation, oxidative damage (replacement of GTP with oxo-8-dGTP), or changes
MTA2 (2,057 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
RARRES1 (531 words) [view diff] exact match in snippet view article find links to article
et al. (2005). "DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1
Representational difference analysis (293 words) [view diff] exact match in snippet view article find links to article
to perform such analyses. This method may also be adapted to detect DNA methylation differences, as seen in methylation-sensitive representational difference
Zootermopsis nevadensis (1,465 words) [view diff] exact match in snippet view article find links to article
1 and 3. This feature shows that exists a functional machinery for DNA methylation. CpG islands meethylation levels in Z. nevadensis are 1.5-3 times higher
ZBTB33 (1,133 words) [view diff] exact match in snippet view article find links to article
HG, Chan DW, Reynolds AB, Qin J, Wong J (Sep 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular
Agouti-signaling protein (3,294 words) [view diff] exact match in snippet view article find links to article
epithelial and mesenchymal tissues. Correct functioning of agouti requires DNA methylation. Methylation occurs in six guanine-cytosine (GC) rich sequences in
TRDMT1 (709 words) [view diff] exact match in snippet view article find links to article
X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein
MBD1 (1,240 words) [view diff] exact match in snippet view article find links to article
H3K9 methyltransferase SETDB1. H3K9me3 is a repressive modification. DNA methylation is the major modification of eukaryotic genomes and plays an essential
Methyl-CpG-binding domain protein 2 (1,440 words) [view diff] exact match in snippet view article find links to article
protein 2 is a protein that in humans is encoded by the MBD2 gene. DNA methylation is the major modification of eukaryotic genomes and plays an essential
Joomyeong Kim (1,008 words) [view diff] exact match in snippet view article find links to article
targeting protein and in neural crest cell development, as well as the DNA methylation of mouse and human retrotransposons. Ph.D. Biochemistry and Molecular
Bromodeoxyuridine (969 words) [view diff] exact match in snippet view article find links to article
Bromodeoxyuridine releases gene silenced by association with the histone caused by DNA methylation. BrdU can also be used to identify microorganisms that respond to specific
EHMT1 (1,592 words) [view diff] case mismatch in snippet view article find links to article
Alves F, et al. (April 2016). "G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells". Cell Reports. 15 (1): 77–85. doi:10.1016/j
Jian-Kang Zhu (2,361 words) [view diff] exact match in snippet view article find links to article
repair pathway for active DNA demethylation to erase DNA methylation marks and to prevent DNA methylation-mediated gene silencing. Zhu’s lab has found nearly
Tiling array (2,025 words) [view diff] exact match in snippet view article find links to article
discovering sites of DNA/protein interaction (ChIP-chip, DamID), of DNA methylation (MeDIP-chip) and of sensitivity to DNase (DNase Chip) and array CGH
Epigenetics of human herpesvirus latency (2,029 words) [view diff] exact match in snippet view article find links to article
through mechanisms such as methylation and acetylation of histones, DNA methylation, and non-coding RNAs (ncRNA). Altering the acetylation of histones
DNA oxidation (4,719 words) [view diff] exact match in snippet view article find links to article
promoter region of a gene, can repress expression of the gene (see DNA methylation in cancer). In general, epigenetic alteration can modulate gene expression
Decitabine (653 words) [view diff] exact match in snippet view article find links to article
upregulates DNA methyltransferase expression, which leads to genome-wide DNA methylation alterations and global gene expression changes. These studies have
KIR2DL4 (1,223 words) [view diff] exact match in snippet view article find links to article
Eisermann B, Meyer KL, Wernet P, Uhrberg M (2002). "Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor
Dirk Schübeler (727 words) [view diff] exact match in snippet view article find links to article
his research group, Schübeler has pioneered approaches to measure DNA methylation, histone modifications and DNA replication at the level of the genome
H3K36me (1,301 words) [view diff] exact match in snippet view article find links to article
alternative splicing, dosage compensation, DNA replication and repair, DNA methylation, and the transmission of the memory of gene expression from parents
IRF8 (2,299 words) [view diff] exact match in snippet view article find links to article
human colon carcinoma cells, suggesting that these cells might use DNA methylation to silence IRF8 expression to advance the disease. IRF8 has been shown
Reduced representation bisulfite sequencing (1,728 words) [view diff] exact match in snippet view article find links to article
representation bisulfite sequencing for comparative high-resolution DNA methylation analysis". Nucleic Acids Res. 33(18):5868-77 Gu H, Smith ZD, Bock C
Neoplasm (5,752 words) [view diff] exact match in snippet view article find links to article
mouse colitis model, and non-essential roles of T- and B-cells in DNA methylation induction". Oncogene. 31 (3): 342–51. doi:10.1038/onc.2011.241. PMID 21685942
Farah Lubin (2,424 words) [view diff] exact match in snippet view article find links to article
of the bdnf gene in fear memory consolidation. She found that bdnf DNA methylation altered bdnf transcription and that blocking BDNF expression in the
Epigenetics of depression (4,264 words) [view diff] exact match in snippet view article find links to article
antidepressants can be used to stabilize moods and decrease global DNA methylation levels, but they could also be used to determine the risk of depression
Robert J. Schmitz (867 words) [view diff] exact match in snippet view article find links to article
developed sets of epi-RILs which have identical DNA but different DNA methylation. By using an enzyme from humans, they can remove the methylation from
NEIL1 (1,840 words) [view diff] exact match in snippet view article find links to article
SA, Vymetalkova V, Vodickova L, Vodicka P, Nilsson TK (Apr 2014). "DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and
H3K27me3 (2,394 words) [view diff] exact match in snippet view article find links to article
H3K27me3 in conjunction with differential expression of H3K4me3 AND DNA methylation may play a factor in Fetal Alcohol Spectrum Disorder (FASD) in C57BL/6J
KDM1B (351 words) [view diff] exact match in snippet view article find links to article
expression by genetic imprinting • regulation of DNA methylation • transcription, DNA-templated • DNA methylation involved in gamete generation • oxidation-reduction
Folami Ideraabdullah (1,996 words) [view diff] exact match in snippet view article find links to article
imprinted gene expression. She found that the deletion did not perturb DNA methylation, though it did impact gene repression and further that the impacts
RBBP7 (1,711 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes Dev. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924. PMC 316920
Mir-542 microRNA precursor family (705 words) [view diff] exact match in snippet view article find links to article
Finazzi-Agrò E, Levine AJ, Melino G, Bernardini S, Candi E (January 2013). "DNA methylation silences miR-132 in prostate cancer". Oncogene. 32 (1): 127–34. doi:10
MSH2 (4,063 words) [view diff] exact match in snippet view article find links to article
signaling module and regulate two branches of the damage response to DNA methylation". Proc. Natl. Acad. Sci. U.S.A. 100 (26): 15387–92. doi:10.1073/pnas
Protein-glutamate O-methyltransferase (718 words) [view diff] exact match in snippet view article find links to article
catechol for regulatory purposes. The various aspects of the role of DNA methylation in prokaryotic restriction-modification systems and in a number of
Cancer Likelihood in Plasma (746 words) [view diff] exact match in snippet view article find links to article
CancerSEEK / DETECT-A ), cfDNA fragmentation patterns (e.g., DELFI), and DNA methylation (e.g., cfMeDIP-Seq, GRAIL). While the CLiP method has not yet been
SRD5A1 (1,614 words) [view diff] exact match in snippet view article find links to article
level of GCLM gene but is not directly mediated by changes in promoter DNA methylation. Insulin increases the expression of 5α-reductase type 1 mRNA via Akt
Stem cell genomics (701 words) [view diff] exact match in snippet view article find links to article
methylated at H3K27me3. Stem cell epigenomic studies are also looking into DNA methylation patterns, specifically characteristics of hydroxy methylation versus
CTCFL (733 words) [view diff] exact match in snippet view article find links to article
PMID 18195709. Woloszynska-Read A, James SR, Link PA, et al. (2008). "DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer".
Vimentin (2,138 words) [view diff] exact match in snippet view article find links to article
adenocarcinoma, and intestinal type gastric cancer. High levels of DNA methylation in the promoter region have also been associated with markedly decreased
Betaine (451 words) [view diff] case mismatch in snippet view article find links to article
Modern Coined Terms and Their Origins. Pergamon. ISBN 978-0080344812. DNA Methylation and Complex Human Disease, Michel Neidhart Rees, William A.; Yager
S-Adenosyl methionine (1,991 words) [view diff] exact match in snippet view article find links to article
SAM-e has recently been shown to play a role in epigenetic regulation. DNA methylation is a key regulator in epigenetic modification during mammalian cell
Cell cycle regulated Methyltransferase (1,513 words) [view diff] exact match in snippet view article find links to article
Schübeler, Dirk (January 2015). "Function and information content of DNA methylation". Nature. 517 (7534): 321–326. doi:10.1038/nature14192. ISSN 1476-4687
DNA damage (naturally occurring) (9,316 words) [view diff] case mismatch in snippet view article
DNA Methylation and MeCP2 in Neuronal Function". Genes. 8 (5): 141. doi:10.3390/genes8050141. PMC 5448015. PMID 28505093. Bird A (January 2002). "DNA
Mucin 17 (426 words) [view diff] exact match in snippet view article find links to article
surface associated". Kitamoto S, Yamada N, Yokoyama S, et al. (2011). "DNA methylation and histone H3-K9 modifications contribute to MUC17 expression". Glycobiology
Reactive oxygen species (7,539 words) [view diff] exact match in snippet view article find links to article
epigenetic modifications in neurons, including alterations in neuronal DNA methylation. The two bodies of information on memory formation appear to be connected
PICK1 (1,460 words) [view diff] exact match in snippet view article find links to article
complex-mediated actin nucleation • monoamine transport • receptor clustering • DNA methylation involved in gamete generation • negative regulation of Arp2/3 complex-mediated
Neuroimmunology (2,707 words) [view diff] exact match in snippet view article find links to article
trials. These three classes include DNA methylation inhibitors, HDAC inhibitors, and RNA-based approaches. DNA methylation inhibitors are used to activate
Small nuclear ribonucleoprotein polypeptide N (1,173 words) [view diff] exact match in snippet view article find links to article
Doerfler W (1997). "Imprinted segments in the human genome: different DNA methylation patterns in the Prader-Willi/Angelman syndrome region as determined
MTRR (gene) (5,246 words) [view diff] exact match in snippet view article
processes influenced by MTRR include: sulfur amino acid metabolic process, DNA methylation, methionine metabolic process, methionine biosynthetic process, methylation
Poly (ADP-ribose) polymerase (2,997 words) [view diff] exact match in snippet view article
post-translational modification of proteins such as CTCF can affect the amount of DNA methylation at CpG dinucleotides (needs references). This regulates the insulator
Fibrosis (884 words) [view diff] exact match in snippet view article find links to article
Baugh JA (2015). "Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis". Fibrogenesis & Tissue Repair. 8: 18. doi:10.1186/s13069-015-0035-8
P16 (4,143 words) [view diff] exact match in snippet view article find links to article
DNA methylation of the p16 gene in esophageal cancer. As the degree of tumor differentiation increased, so did the frequency of p16 DNA methylation.
5-Hydroxymethylcytosine (1,740 words) [view diff] exact match in snippet view article find links to article
of 5-hydroxymethylcytosine some concerns have been raised regarding DNA methylation studies using the bisulfite sequencing technique. 5-hydroxymethylcytosine
GPS2 (gene) (1,317 words) [view diff] exact match in snippet view article
HG, Chan DW, Reynolds AB, Qin J, Wong J (Sep 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular
C11orf52 (646 words) [view diff] exact match in snippet view article find links to article
reptiles and birds. There are no paralogs for the C11orf52 gene. Unusual DNA methylation in the C11orf52 gene in some children can be attributed to prenatal
Homeobox (4,309 words) [view diff] exact match in snippet view article find links to article
to be dysregulated in several cancers and are often controlled by DNA methylation. The regulation of Hox genes is highly complex and involves reciprocal
SLC22A8 (1,082 words) [view diff] case mismatch in snippet view article find links to article
Organic Anion Transporter 3 by Hepatocyte Nuclear Factor 1 /beta and DNA Methylation". Molecular Pharmacology. 70 (3): 887–96. doi:10.1124/mol.106.025494
DNA-PKcs (3,160 words) [view diff] exact match in snippet view article find links to article
strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island". PLOS Genetics. 4 (8): e1000155
Flavan-4-ol (212 words) [view diff] case mismatch in snippet view article find links to article
Sekhon, Rajandeep S.; Chopra, Surinder (2009). "Progressive Loss of DNA Methylation Releases Epigenetic Gene Silencing from a Tandemly Repeated Maize Myb
GlaxoSmithKline Prize (135 words) [view diff] exact match in snippet view article find links to article
outstanding contributions in the field of epigenetics, especially DNA methylation and its role in development and disease." - 2014 Nicholas Lydon "for
Crick Lecture (440 words) [view diff] exact match in snippet view article find links to article
17 April 2019. Klose, Robert J.; Bird, Adrian P. (2006). "Genomic DNA methylation: the mark and its mediators". Trends in Biochemical Sciences. 31 (2):
FANCF (2,425 words) [view diff] exact match in snippet view article find links to article
strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island". PLOS Genetics. 4 (8): e1000155
Oxoguanine glycosylase (2,494 words) [view diff] exact match in snippet view article find links to article
Kristensen VN, Tost J (June 2014). "Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points
XPC (gene) (1,923 words) [view diff] exact match in snippet view article
strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island". PLOS Genetics. 4 (8): e1000155
Trefoil factor 1 (1,273 words) [view diff] exact match in snippet view article find links to article
frequently lost in gastric carcinoma, probably through mechanism of DNA methylation, and it is therefore considered as a tumor suppressor gene. GRCh38:
Insulin-like growth factor 2 (1,512 words) [view diff] case mismatch in snippet view article find links to article
(2016). DNA Methylation and Complex Human Disease (1st ed.). San Diego: Academic Press. p. 222. ISBN 9780124201941. Neidhart, M (2016). DNA Methylation and
Aviv Regev (724 words) [view diff] case mismatch in snippet view article find links to article
Institute. Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?". Molecular
Immunodeficiency–centromeric instability–facial anomalies syndrome (449 words) [view diff] exact match in snippet view article find links to article
Moncla, A; Viegas-Péquignot, E (January 2005). "DNMT3B mutations and DNA methylation defect define two types of ICF syndrome". Human Mutation. 25 (1): 56–63
KMT2A (2,393 words) [view diff] exact match in snippet view article find links to article
acetylation • positive regulation of transcription, DNA-templated • DNA methylation • histone H3-K4 methylation • methylation • positive regulation of
SAP30 (1,825 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
Gastrointestinal cancer (2,570 words) [view diff] exact match in snippet view article find links to article
that field cancerization occurs in the colon, often due to aberrant DNA methylation. Yamada T, Alpers DH, et al. (2009). Textbook of gastroenterology (5th
Gs alpha subunit (774 words) [view diff] exact match in snippet view article find links to article
• post-embryonic development • post-embryonic body morphogenesis • DNA methylation • cartilage development • positive regulation of osteoblast differentiation
Babraham Institute (924 words) [view diff] exact match in snippet view article find links to article
Michael Berridge, the discovery that genomic imprinting was carried by DNA methylation by Wolf Reik. Many of its past and current employees were elected fellows
Histone deacetylase 2 (4,492 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
HEMK1 (72 words) [view diff] exact match in snippet view article find links to article
methyltransferase activity Cellular component • mitochondrion Biological process • DNA methylation • protein methylation • methylation Sources:Amigo / QuickGO
Columbia University Mailman School of Public Health (1,781 words) [view diff] case mismatch in snippet view article find links to article
School offers a summer Epigenetic Boot Camp for Planning and Analyzing DNA Methylation Studies, a two-day intensive boot camp of seminars and hands-on analytical
RBBP4 (2,139 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes Dev. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924. PMC 316920
Columbia University Mailman School of Public Health (1,781 words) [view diff] case mismatch in snippet view article find links to article
School offers a summer Epigenetic Boot Camp for Planning and Analyzing DNA Methylation Studies, a two-day intensive boot camp of seminars and hands-on analytical
Transcription factor binding site databases (849 words) [view diff] exact match in snippet view article find links to article
specific database of transcription factor binding motifs coupled with DNA methylation profiles". Nucleic Acids Research. 47 (D1): D145–D154. doi:10.1093/nar/gky1005
Cytosine (798 words) [view diff] exact match in snippet view article find links to article
bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis — A personal account". Proceedings of the Japan Academy. Series
TBL1XR1 (1,020 words) [view diff] exact match in snippet view article find links to article
Chan DW, Reynolds AB, Qin J, Wong J (September 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular
EIF3A (1,354 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes Dev. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924. PMC 316920
Choroid plexus carcinoma (871 words) [view diff] case mismatch in snippet view article find links to article
1159/000028933. PMID 10940770. S2CID 20244382. Dricua A, et al. (Dec 1999). DNA Methylation, Stem Cells and Cancer. Rickert CH, Paulus W (Jan 2001). "Tumors of
Mixed connective tissue disease (3,119 words) [view diff] exact match in snippet view article find links to article
discovered. DNA methylation may affect the as yet unknown genetic risks of this disease as patients with MCTD have decreased DNA methylation levels in opposition
TMCO5A (158 words) [view diff] exact match in snippet view article find links to article
"Progression-free survival in ovarian cancer is reflected in epigenetic DNA methylation profiles". Oncology. 80 (1–2): 12–20. doi:10.1159/000327746. PMID 21577013
PCTK1 (905 words) [view diff] exact match in snippet view article find links to article
Hunt PA, Lawrence JB, Willard HF (1996). "X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in
SPRY4 (521 words) [view diff] exact match in snippet view article find links to article
"Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer". The Prostate. 66 (6): 613–24. doi:10.1002/pros
NLRP7 (632 words) [view diff] exact match in snippet view article find links to article
mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation". Hum. Genet. 120 (3): 390–5. doi:10.1007/s00439-006-0192-3. PMID 16874523
DAPK2 (683 words) [view diff] exact match in snippet view article find links to article
PMC 2173279. PMID 11980920. Satoh A, Toyota M, Itoh F, et al. (2002). "DNA methylation and histone deacetylation associated with silencing DAP kinase gene
HOXA3 (889 words) [view diff] exact match in snippet view article find links to article
PMID 25249461. Han L, Witmer PD, Casey E, Valle D, Sukumar S (August 2007). "DNA methylation regulates MicroRNA expression". Cancer Biology & Therapy. 6 (8): 1284–8
Trans-acting siRNA (1,143 words) [view diff] exact match in snippet view article find links to article
argonaute proteins in TAS-derived small interfering RNA-triggered DNA methylation". Plant Physiol. 160 (2): 990–9. doi:10.1104/pp.112.200279. PMC 3461571
Demethylating agent (348 words) [view diff] exact match in snippet view article find links to article
sort of viral mimicry inside the cell. Holliday, R.; Ho, T. (2002). "DNA methylation and epigenetic inheritance". Methods. 27 (2): 179–83. doi:10
Neuropeptides B/W receptor 1 (1,058 words) [view diff] exact match in snippet view article find links to article
Kristiansen G, et al. (2007). "Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis". J. Urol. 177 (5): 1753–8. doi:10
Lieber Institute for Brain Development (1,265 words) [view diff] exact match in snippet view article find links to article
researchers found that patients with schizophrenia had high levels of DNA methylation in brain regions associated with risk for schizophrenia. They are also
C8orf46 (929 words) [view diff] exact match in snippet view article find links to article
Ruth; Stirzaker, Clare; Graham, Peter; Trau, Matt (2015-07-14). "DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast
Alpha-1D adrenergic receptor (1,027 words) [view diff] exact match in snippet view article find links to article
regulation of human α1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation". FASEB J. 21 (9): 1979–93. doi:10.1096/fj
Wolf Prize in Medicine (162 words) [view diff] exact match in snippet view article find links to article
their fundamental contributions to our understanding of the role of DNA methylation in the control of gene expression. 2009 No award 2010 Axel Ullrich
CodonCode Aligner (828 words) [view diff] exact match in snippet view article find links to article
areas, including HIV research, biogeography and environmental biology, DNA methylation studies, genetic diseases, clinical microbiology, and evolution research
Green-legged Partridge (519 words) [view diff] case mismatch in snippet view article find links to article
Grazyna Jezewska-Witkowska (2013). Analysis of Age-Related Global DNA Methylation in Chicken. Biochemical Genetics 51 (7–8): 554–563. doi:10.1007/s10528-013-9586-9
Fertility testing (922 words) [view diff] exact match in snippet view article find links to article
Andrew D. Smith; Douglas T. Carrell (December 2015). "Aberrant sperm DNA methylation predicts male fertility status and embryo quality". Fertility and Sterility
BAZ2A (420 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated • transcription, DNA-templated • DNA methylation • chromatin silencing at rDNA • histone deacetylation • RNA polymerase
GNAS-AS1 (339 words) [view diff] exact match in snippet view article find links to article
835. PMID 10749992. Tobi EW, Lumey LH, Talens RP, et al. (2009). "DNA methylation differences after exposure to prenatal famine are common and timing-
Rex1 (1,731 words) [view diff] exact match in snippet view article find links to article
epigenetic changes. YY1 has been shown to be involved in setting up DNA methylation on the maternal allele of PEG3 during oogenesis. Rex1 was found to
Liz Dennis (1,189 words) [view diff] exact match in snippet view article find links to article
down-regulated by vernalisation. They also observed that a reduction in DNA methylation plays an important role in this response to cold. The mechanism involves
TDRKH (375 words) [view diff] exact match in snippet view article find links to article
meiotic nuclear division • fertilization • cell differentiation • DNA methylation involved in gamete generation • spermatogenesis • gene silencing by
Andrew Singleton (948 words) [view diff] case mismatch in snippet view article find links to article
Flint, Jonathan (ed.). "Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain". PLOS Genetics. 6 (5): e1000952
SMN2 (1,340 words) [view diff] exact match in snippet view article find links to article
Hahnen E (January 2009). "Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be
SPRY3 (526 words) [view diff] exact match in snippet view article find links to article
Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications". Hum
Michael Wigler (2,200 words) [view diff] exact match in snippet view article find links to article
stability of expression in host cells, demonstrating the inheritance of DNA methylation patterns, and isolating the first vertebrate genes, and first human
TRIM33 (1,023 words) [view diff] exact match in snippet view article find links to article
Chan DW, Reynolds AB, Qin J, Wong J (September 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular
Andrew Singleton (948 words) [view diff] case mismatch in snippet view article find links to article
Flint, Jonathan (ed.). "Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain". PLOS Genetics. 6 (5): e1000952
CDCP1 (1,481 words) [view diff] exact match in snippet view article find links to article
Tomita Y, Shibayama H, Kanakura Y, Aozasa K (September 2006). "Role of DNA methylation for expression of novel stem cell marker CDCP1 in hematopoietic cells"
ASZ1 (376 words) [view diff] exact match in snippet view article find links to article
differentiation • GO:0007126 meiotic cell cycle • spermatogenesis • DNA methylation involved in gamete generation • gene silencing by RNA • signal transduction
SPRYD7 (449 words) [view diff] exact match in snippet view article find links to article
suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia". Blood. 99 (11): 4116–21
CYP2S1 (1,314 words) [view diff] case mismatch in snippet view article find links to article
(2016). "Epigenome-Wide Association Analysis Identified Nine Skin DNA Methylation Loci for Psoriasis". The Journal of Investigative Dermatology. 136
AGBL4 (301 words) [view diff] case mismatch in snippet view article find links to article
Tsai SF, Chang SC (December 2015). "Clinical Relevance of Plasma DNA Methylation in Colorectal Cancer Patients Identified by Using a Genome-Wide High-Resolution
Task allocation and partitioning of social insects (3,732 words) [view diff] exact match in snippet view article find links to article
differences in DNA methylation, which causes differences in gene expression. Reverting foragers to nurses by removing younger workers causes changes in DNA methylation
Neuroepigenetics (3,572 words) [view diff] exact match in snippet view article find links to article
A, Minucci S, Pelicci PG (January 2008). "Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases
KMT2E (249 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated • transcription, DNA-templated • DNA methylation • cell cycle arrest • erythrocyte differentiation • cell cycle • neutrophil
HMCES (250 words) [view diff] exact match in snippet view article find links to article
C, Faull RL, Curtis MA, Dragunow M (June 2014). "Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain". Neurobiol
MPHOSPH8 (351 words) [view diff] exact match in snippet view article find links to article
complex • cytosol • heterochromatin Biological process • regulation of DNA methylation • negative regulation of transcription, DNA-templated • regulation
MIS18A (572 words) [view diff] exact match in snippet view article find links to article
chromatin • cytosol Biological process • cell division • regulation of DNA methylation • cell cycle • chromosome segregation • CENP-A containing nucleosome
COSMIC cancer database (863 words) [view diff] exact match in snippet view article find links to article
Cytogenetics in Oncology and Haematology MethyCancer, a database of human DNA methylation and cancer COSMIC in the bioinformatics.ca Links Directory
RLF (gene) (424 words) [view diff] exact match in snippet view article
positive regulation of transcription from RNA polymerase II promoter • regulation of DNA methylation • histone H3-K4 monomethylation Sources:Amigo / QuickGO
CDX1 (1,184 words) [view diff] exact match in snippet view article find links to article
Suh ER, Ha CS, Rankin EB, Toyota M, Traber PG (September 2002). "DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines"
ATF7IP (709 words) [view diff] exact match in snippet view article find links to article
Biological process • positive regulation of transcription, DNA-templated • DNA methylation • regulation of RNA polymerase II transcriptional preinitiation complex
KIR3DL2 (1,145 words) [view diff] exact match in snippet view article find links to article
PMC 139241. PMID 12477932. Chan HW, Kurago ZB, Stewart CA, et al. (2003). "DNA methylation maintains allele-specific KIR gene expression in human natural killer
HOXD10 (1,099 words) [view diff] exact match in snippet view article find links to article
S2CID 4421050. Han L, Witmer PD, Casey E, Valle D, Sukumar S (Aug 2007). "DNA methylation regulates MicroRNA expression". Cancer Biology & Therapy. 6 (8): 1284–8
CBX5 (gene) (2,386 words) [view diff] exact match in snippet view article
(Jul 2003). "Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin". Current
Obligate carrier (832 words) [view diff] exact match in snippet view article find links to article
PMID 22178198. Riggs, A.D. (1975). "X inactivation, differentiation, and DNA methylation". Cytogenet Cell Genet. 14: 9–25. doi:10.1159/000130315. PMID 1093816
SIN3B (1,090 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
RAD52 (2,982 words) [view diff] exact match in snippet view article find links to article
strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island". PLOS Genetics. 4 (8): e1000155
Survivin (8,370 words) [view diff] exact match in snippet view article find links to article
However, De Carvalho et al. performed a DNA methylation screening and identified that DNA methylation of IRAK3 plays a key role in survivin up-regulation
Methyltransferase like 4 (68 words) [view diff] exact match in snippet view article find links to article
(adenine-specific) activity Cellular component • cell nucleus Biological process • methylation • DNA methylation on adenine Sources:Amigo / QuickGO
Osteoprotegerin (3,675 words) [view diff] exact match in snippet view article find links to article
OPG gene. Downregulation of OPG can be effected by TGF-β1, PTH and DNA methylation of a CpG island in the OPG gene. OPG expression in osteoblast lineage
CYTL1 (474 words) [view diff] exact match in snippet view article find links to article
Bae JB, Kim YJ, Park JH (January 2012). "Genome-wide analysis of DNA methylation and the gene expression change in lung cancer". Journal of Thoracic
Mi-2/NuRD complex (557 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
Cyclin-dependent kinase inhibitor 1C (1,589 words) [view diff] exact match in snippet view article find links to article
Hatano S, Ito E, Mori N, Saito H, Kinoshita T (Oct 2002). "Aberrant DNA methylation of p57(KIP2) gene in the promoter region in lymphoid malignancies of
Unexplained infertility (819 words) [view diff] exact match in snippet view article find links to article
Andrew D. Smith; Douglas T. Carrell (December 2015). "Aberrant sperm DNA methylation predicts male fertility status and embryo quality". Fertility and Sterility
Xu Guoliang (267 words) [view diff] exact match in snippet view article find links to article
the cells. In 2014, he published his study concerning the effect of DNA methylation and histone modification. In 2013, Xu was awarded the TWAS Prize "for
UHRF2 (445 words) [view diff] exact match in snippet view article find links to article
cycle • cell differentiation • cellular proliferation • maintenance of DNA methylation • protein ubiquitination • regulation of cell cycle • protein sumoylation
Glioma (5,296 words) [view diff] exact match in snippet view article find links to article
A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal.pgen.0030110. PMC 1913100
ZGPAT (445 words) [view diff] exact match in snippet view article find links to article
N, Leon J, Martienssen RA, Jeddeloh JA (Nov 2006). "Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets"
TMEFF2 (889 words) [view diff] exact match in snippet view article find links to article
Iizasa T, Frenkel EP, Minna JD, Fujisawa T, Gazdar AF (October 2005). "DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3
TBX3 (4,718 words) [view diff] exact match in snippet view article find links to article
(September 2014). "Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate
Polbar (212 words) [view diff] case mismatch in snippet view article find links to article
Grazyna Jezewska-Witkowska (2013). Analysis of Age-Related Global DNA Methylation in Chicken. Biochemical Genetics 51 (7-8): 554–563. doi:10.1007/s10528-013-9586-9
Colorectal cancer (11,823 words) [view diff] exact match in snippet view article find links to article
confirmed with clinical studies. Epigenetic factors, such as abnormal DNA methylation of tumor suppressor promoters, play a role in the development of colorectal
KLF13 (1,466 words) [view diff] exact match in snippet view article find links to article
Larsson EM, Rask-Andersen M, Benedict C, Schiöth HB (14 Feb 2017). "A DNA methylation site within the KLF13 gene is associated with orexigenic processes
Epigenetic regulation of transposable elements in the plant kingdom (2,221 words) [view diff] case mismatch in snippet view article find links to article
in which siRNA transposon transcript is loaded onto an RNA-Directed DNA Methylation complex, which methylates the region of DNA which is reactive to the
CSPG4 (1,478 words) [view diff] exact match in snippet view article find links to article
weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells". Oncogene. 25 (20): 2873–84. doi:10.1038/sj
ANK1 (1,624 words) [view diff] exact match in snippet view article find links to article
Bennett, D. A. (2014). "Alzheimer's disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci". Nature Neuroscience. 17 (9):
Maelstrom gene (449 words) [view diff] exact match in snippet view article find links to article
Zhou JA (2010). Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation. Molecular Biology Reports. 37: 2355-2360.
MTSS1 (739 words) [view diff] exact match in snippet view article find links to article
"The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation". Int. J. Cancer. 119 (10): 2287–93. doi:10.1002/ijc.22106. PMID 16921485
Nanjing Medical University (1,028 words) [view diff] case mismatch in snippet view article find links to article
Hong Kong.. Springer; 8 October 2010. ISBN 978-90-481-9382-0. Plasma DNA Methylation Analysis in Predicting Short-Term Recurrence of Surgical Patients with
C16orf86 (2,431 words) [view diff] exact match in snippet view article find links to article
with GWAS to figure out the DNA methylation profiles at day 3, day 8, and day 15 for skeletal myoblasts. This DNA methylation at day 3, day 8, and day 15
ZFP57 (480 words) [view diff] exact match in snippet view article find links to article
DNA-templated • regulation of gene expression by genetic imprinting • DNA methylation involved in embryo development • Duncan Kiige Sources:Amigo / QuickGO
Scaffold/matrix attachment region (1,023 words) [view diff] no match in snippet view article find links to article
poly(ADP-ribosyl) polymerases and enzymes of the histone-acetylation and DNA-methylation apparatus). S/MARs have been classified as either being constitutive
NLRC4 (1,180 words) [view diff] exact match in snippet view article find links to article
SM, McElwaine SM, Cotter FE, Newland AC, Jia L (Jan 2003). "Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia". Oncogene
Douglas Higgs (921 words) [view diff] exact match in snippet view article find links to article
encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation". Nature Genetics. 24 (4): 368–371. doi:10.1038/74191. ISSN 1546-1718
H1FOO (486 words) [view diff] exact match in snippet view article find links to article
GO:0007126 meiotic cell cycle • nucleosome positioning • regulation of DNA methylation • negative regulation of stem cell differentiation • regulation of
CORO2A (442 words) [view diff] exact match in snippet view article find links to article
Chan DW, Reynolds AB, Qin J, Wong J (September 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular
Elymus canadensis (947 words) [view diff] exact match in snippet view article find links to article
chromosomes in the hybrids was not random, and were caused by differences in DNA methylation. Thus, further research can use these differences in order to figure
Virus latency (1,993 words) [view diff] case mismatch in snippet view article find links to article
Minarovits J (2006). "Epigenotypes of Latent Herpesvirus Genomes". DNA Methylation: Development, Genetic Disease and Cancer. Current Topics in Microbiology
SMCHD1 (313 words) [view diff] exact match in snippet view article find links to article
by inactivation of X chromosome • inactivation of X chromosome by DNA methylation • chromosome organization • nose development • double-strand break
HSV epigenetics (2,241 words) [view diff] exact match in snippet view article find links to article
have been well described: chromatin assembly, histone modifications, DNA methylation, and regulatory RNA. Upon initial infection, viral genomes are not
Targeted analysis sequencing (198 words) [view diff] case mismatch in snippet view article find links to article
D.R.; Stanford, D.R.; Freeman, W.M. (24 February 2015). "Targeted DNA Methylation Analysis by Next-generation Sequencing". Journal of Visualized Experiments
Interleukin 6 (6,478 words) [view diff] exact match in snippet view article find links to article
metastasis through down-regulation of E-cadherin, and alteration of DNA methylation in oral cancer. Advanced/metastatic cancer patients have higher levels
Richard Deth (712 words) [view diff] exact match in snippet view article find links to article
conversion of dietary forms of B12 into the active form and so impedes DNA methylation and disrupts mercury detoxification and some normal gene actions. Based
Nadine Provençal (433 words) [view diff] exact match in snippet view article find links to article
neurogenesis primes future stress response by inducing changes in DNA methylation which found that when fetuses are exposures to stress during pregnancy
Ruth Stephens Gani Medal (408 words) [view diff] exact match in snippet view article find links to article
on or off. He has also discovered that a ‘punctuation mark’ called DNA methylation can instruct the accurate usage of spacer sequences. The work by Dr
Genome instability (4,532 words) [view diff] exact match in snippet view article find links to article
Avvedimento, EV (2007). "DNA damage, homology-directed repair, and DNA methylation". PLoS Genet. 3 (7): e110. doi:10.1371/journal.pgen.0030110. PMC 1913100
Frances Champagne (1,925 words) [view diff] exact match in snippet view article find links to article
aromatic hydrocarbon exposure on behavior, cortical gene expression, and DNA methylation of the Bdnf gene. Neuroepigenetics 5: 11-18. PMID 27088078 Jensen Peña
Ifood (581 words) [view diff] case mismatch in snippet view article find links to article
Norbert O; Shchepinov, Mikhail S (2016). "Rational Manipulation of DNA Methylation by Using Isotopically Reinforced Cytosine". ChemBioChem. 17 (21): 2018–2021
Secreted frizzled-related protein 1 (6,274 words) [view diff] exact match in snippet view article find links to article
cancers (46%) Malignant mesotheliomas (48%) Colorectal cancers (76%) DNA methylation involves the addition of a methyl group to the carbon-5 position of
Histone H1 (2,212 words) [view diff] exact match in snippet view article find links to article
organism-specific defects in nuclear morphology, chromatin structure, DNA methylation, and/or specific gene expression. While most histone H1 in the nucleus
Stereocilia (inner ear) (2,208 words) [view diff] exact match in snippet view article
1093/hmg/ddt549. PMID 24191262. Retrieved December 3, 2015. Lee, Hwajin (2012). "DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational
HOXA6 (678 words) [view diff] exact match in snippet view article find links to article
"Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses". Carcinogenesis. 33 (2): 436–41. doi:10.1093/carcin/bgr260
Multiplex ligation-dependent probe amplification (1,486 words) [view diff] exact match in snippet view article find links to article
detection of mutations and single nucleotide polymorphisms, analysis of DNA methylation, relative mRNA quantification, chromosomal characterisation of cell
Institute of Molecular Biology (450 words) [view diff] case mismatch in snippet view article find links to article
(Christof Niehrs) Gene Expression, Transcriptional Cycling and Dynamic DNA Methylation (George Reid) Epigenetic Mechanisms of Cellular Differentiation and
Stereocilia (inner ear) (2,208 words) [view diff] exact match in snippet view article
1093/hmg/ddt549. PMID 24191262. Retrieved December 3, 2015. Lee, Hwajin (2012). "DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational
Hiroyuki Sasaki (407 words) [view diff] exact match in snippet view article find links to article
Watanabe T; et al. (2011). "Role for piRNAs and non-coding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus". Science. 332 (6031): 848–852
HAND2 (1,787 words) [view diff] exact match in snippet view article find links to article
HB, Bagchi MK, Bagchi IC, Widschwendter M (November 2013). "Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development"
Animal testing on rodents (1,963 words) [view diff] exact match in snippet view article find links to article
PMID 15669134. Murgatroyd, C; et al. (8 November 2009). "Dynamic DNA methylation programs persistent adverse effects of early-life stress". Nature Neuroscience
SNRPN upstream reading frame protein (907 words) [view diff] exact match in snippet view article find links to article
Surti U, Driscoll DJ, Nicholls RD (February 1996). "Gene structure, DNA methylation, and imprinted expression of the human SNRPN gene". American Journal
Surfactant protein A1 (3,339 words) [view diff] exact match in snippet view article find links to article
PMC 3191759. PMID 21784968. Vaid M, Floros J (Jan 2009). "Surfactant protein DNA methylation: a new entrant in the field of lung cancer diagnostics? (Review)".
MIZF (758 words) [view diff] exact match in snippet view article find links to article
histone deacetylase (HDAC) complex. MIZF is thought to play a role in DNA methylation and transcription repression.[supplied by OMIM] One key partner protein
ZBTB32 (1,640 words) [view diff] exact match in snippet view article find links to article
promoter, results in the development of aggressive breast cancers. A DNA methylation correlation network was built based on the methylation correlation
Bivalent chromatin (927 words) [view diff] exact match in snippet view article find links to article
permanently by repelling transcription repressors and blocking repressive DNA methylation. Once the cell has differentiated to a specific type of cell only one
Surfactant protein A2 (3,577 words) [view diff] exact match in snippet view article find links to article
PMID 20466729. Vaid M, Floros J (January 2009). "Surfactant protein DNA methylation: a new entrant in the field of lung cancer diagnostics? (Review)".
Barbara Tudek (437 words) [view diff] exact match in snippet view article find links to article
2009: The effect of early life nutritional exposures on repair and DNA methylation in brain tissue from young piglets 2009: Cockayne syndrome group B
CHD4 (1,313 words) [view diff] exact match in snippet view article find links to article
subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes & Development. 13 (15): 1924–35. doi:10.1101/gad.13.15.1924
Pikachurin (1,254 words) [view diff] exact match in snippet view article find links to article
XH, Lu Y, Ma D, Liu XS, Guo SW (October 2009). "[Model of aberrant DNA methylation patterns and its applications in epithelial ovarian cancer.]". Zhonghua
GNAS complex locus (1,688 words) [view diff] exact match in snippet view article find links to article
• post-embryonic development • post-embryonic body morphogenesis • DNA methylation • cartilage development • positive regulation of osteoblast differentiation
XAF1 (1,042 words) [view diff] exact match in snippet view article find links to article
full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor". Int. J. Cancer. 118 (10): 2485–9. doi:10.1002/ijc.21636
Cadherin (2,707 words) [view diff] exact match in snippet view article find links to article
AK, Kim S, Lababidi S, Scherf U, et al. (February 2007). "Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells". Molecular
Mir-184 (2,131 words) [view diff] exact match in snippet view article find links to article
of MeCP2 after depolarization, suggesting a link between miRNAs and DNA methylation pathways . J. Yu et al. demonstrated that the lipid phosphatase SH2-containing
EGR1 (1,440 words) [view diff] exact match in snippet view article find links to article
TET1 protein that initiates a pathway of DNA demethylation. Removing DNA methylation marks allows the activation of downstream genes. EGR-1, together with
Oncostatin M receptor (1,626 words) [view diff] exact match in snippet view article find links to article
Meijer GA, Van Criekinge W, Sidransky D (August 2009). "Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic
SUV39H1 (1,469 words) [view diff] exact match in snippet view article find links to article
(MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression". J. Biol. Chem. 278 (26): 24132–8
CLIP4 (1,579 words) [view diff] exact match in snippet view article find links to article
gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies". Oncotarget. 8 (24): 38501–38516. doi:10.18632/oncotarget
Ventricular zone (715 words) [view diff] exact match in snippet view article find links to article
Neuroscience. 16 (19): 6183–96. PMID 8815900. Wang Z, Tang B, He Y, Jin P. DNA methylation dynamics in neurogenesis. Epigenomics. 2016 Mar;8(3):401-14. doi:10
H3K9me2 (2,590 words) [view diff] case mismatch in snippet view article find links to article
Alves F, et al. (April 2016). "G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells". Cell Reports. 15 (1): 77–85. doi:10.1016/j
Ras association domain family member 7 (328 words) [view diff] exact match in snippet view article find links to article
RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma". Mol. Cancer. 11: 40. doi:10.1186/1476-4598-11-40
HS3ST2 (679 words) [view diff] case mismatch in snippet view article find links to article
(glucosamine) 3-O-sulfotransferase 2". Dietrich, Dimo (2009). "Analysis of DNA Methylation of Multiple Genes in Microdissected Cells From Formalin-fixed and Paraffin-embedded
DMAP1 (1,080 words) [view diff] exact match in snippet view article find links to article
transcription from RNA polymerase II promoter • transcription, DNA-templated • DNA methylation • regulation of growth • response to ethanol • DNA repair • negative
Radiation-induced cancer (6,019 words) [view diff] exact match in snippet view article find links to article
decrease in global DNA methylation than acute irradiation, causing 2.5- and 6.1-fold (P < 0.05) reduction in global DNA methylation Rothkamm K, Löbrich
EHMT2 (1,743 words) [view diff] exact match in snippet view article find links to article
negative regulation of transcription from RNA polymerase II promoter • DNA methylation • methylation • peptidyl-lysine dimethylation • histone lysine methylation
TBL1X (929 words) [view diff] exact match in snippet view article find links to article
Yoon HG, Chan DW, Reynolds AB, Qin J, Wong J (2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Mol
Endogenous retrovirus (6,887 words) [view diff] exact match in snippet view article find links to article
they were endogenized; however, this also may be due to a lack of DNA methylation in germ-line tissues. The best-characterized instance of placental
Muscle memory (4,652 words) [view diff] exact match in snippet view article find links to article
went on to examine the human epigenome in order to understand how DNA methylation may aid in creating this effect. During the first period of resistance
Urbanization (9,264 words) [view diff] exact match in snippet view article find links to article
matter with a diameter of less than 2.5 micrometers (PM2.5), can cause DNA methylation of CpG sites in immune cells, which increases children's risk of developing
SUV420H1 (668 words) [view diff] exact match in snippet view article find links to article
PMID 15489334. Tryndyak VP, Kovalchuk O, Pogribny IP (2006). "Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells
DNase I hypersensitive site (907 words) [view diff] exact match in snippet view article find links to article
factors is implicated in the remodeling and accessibility of chromatin. DNA methylation patterns: CpG methylation has been closely linked with transcriptional
Ridge (biology) (3,446 words) [view diff] exact match in snippet view article
regulated by different phyla. For example, in vertebrates and plants DNA methylation is used, whereas it is absent in yeast and flies. Chromatin DNA sequence
H3K4me1 (1,594 words) [view diff] case mismatch in snippet view article find links to article
07.050. PMC 5821249. PMID 27518561. Neidhart, Michel (2015-09-17). DNA Methylation and Complex Human Disease. p. 124. ISBN 978-0-12-420194-1. "Whole-Genome
CHD3 (1,390 words) [view diff] exact match in snippet view article find links to article
Ballestar E, Aubry F, Wolffe AP (Sep 1999). "Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation". Nature Genetics
Déborah Bourc'his (473 words) [view diff] exact match in snippet view article find links to article
shows that germline cells require a specific stimulation to acquire DNA methylation, via the cofactor 3 DNMT3L. Déborah Bourch'his runs a research team
Argonaute (1,934 words) [view diff] exact match in snippet view article find links to article
itself. AGO4 does not involve in RNAi directed RNA degradation, but in DNA methylation and other epigenetic regulation, through small RNA (smRNA) pathway
Protein SET (1,242 words) [view diff] exact match in snippet view article find links to article
acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing". The Journal of Biological Chemistry
PD-L1 (2,479 words) [view diff] exact match in snippet view article find links to article
been shown to regulate LMP1 induced PD-L1 expression. PD-L1 promoter DNA methylation may predict survival in some cancers after surgery. It appears that
GNMT (3,104 words) [view diff] exact match in snippet view article find links to article
019273. PMC 2755656. PMID 19483083. McCabe DC, Caudill MA (2005). "DNA methylation, genomic silencing, and links to nutrition and cancer". Nutrition Reviews
Pou class 3 homeobox 3 (218 words) [view diff] exact match in snippet view article find links to article
levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells". Gastroenterology. 146
Trinucleotide repeat containing 18 (1,213 words) [view diff] exact match in snippet view article find links to article
filtration rate (eGFR), 5 were also linked with renal fibrosis and DNA methylation occurrences in the kidney cortex of chronic kidney disease (CKD) patients
Marnie Blewitt (653 words) [view diff] exact match in snippet view article find links to article
NK, Paldi A Koseki H and Whitelaw E (2006) Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice. PLoS Genetics April
Retrotransposon (3,010 words) [view diff] exact match in snippet view article find links to article
S2CID 22129236. Walter M (2015). "Transposon regulation upon dynamic loss of DNA methylation (PDF Download Available)". ResearchGate. doi:10.13140/rg.2.2.18747
Morc family cw-type zinc finger 1 (208 words) [view diff] exact match in snippet view article find links to article
regulation of transposition • epigenetic regulation of gene expression • DNA methylation involved in gamete generation • DNA hypermethylation • negative regulation
Tc1/mariner (1,795 words) [view diff] exact match in snippet view article find links to article
Walter, Marius (2016). Transposon regulation upon dynamic loss of DNA methylation (Thesis). Université Pierre et Marie Curie. doi:10.13140/rg.2.2.18747
Owen Smith (physician) (583 words) [view diff] exact match in snippet view article
cancer cells could be broken into three subgroups through analysis of DNA methylation. Smith and his wife Jude have three children together. In 2019, Smith
Long non-coding RNA (11,692 words) [view diff] exact match in snippet view article find links to article
Tsix (see above). Epigenetic modifications, including histone and DNA methylation, histone acetylation and sumoylation, affect many aspects of chromosomal
Carbonic anhydrase III, muscle specific (1,042 words) [view diff] exact match in snippet view article find links to article
et al. (1987). "Human muscle carbonic anhydrase: gene structure and DNA methylation patterns in fetal and adult tissues". Genes Dev. 1 (6): 594–602. doi:10
Mir-452 microRNA precursor family (562 words) [view diff] exact match in snippet view article find links to article
Maurya PK, Su CM, Tzeng CR (April 2012). "MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice". Molecular Human
Chromosome conformation capture (4,855 words) [view diff] exact match in snippet view article find links to article
postulated the epigenetic landscapes. In 1948, Rollin Hotchkiss discovered DNA methylation. In 1953, Watson and Crick discovered the double helix structure of
Deleted in lung and esophageal cancer 1 (693 words) [view diff] exact match in snippet view article find links to article
2008). "The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle". J
TLR9 (2,443 words) [view diff] exact match in snippet view article find links to article
Jordan CK, McGovern JL, Brown MA, Ehrenstein MR (February 2017). "DNA methylation governs the dynamic regulation of inflammation by apoptotic cells during
Gregory L. Verdine (1,425 words) [view diff] exact match in snippet view article find links to article
School, Verdine has elucidated the molecular mechanism of epigenetic DNA methylation and pathways by which certain genotoxic forms of DNA damage are surveilled
Ewing's sarcoma (3,221 words) [view diff] no match in snippet view article find links to article
D, Stichel D, Jabar S, Ranft A, et al. (August 2018). "Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides
TRIM28 (2,240 words) [view diff] exact match in snippet view article find links to article
phosphorylation • protein oligomerization • autophosphorylation • DNA methylation involved in embryo development • Ras protein signal transduction •
Molecular pathological epidemiology (1,919 words) [view diff] exact match in snippet view article find links to article
Shanmugam K (January 2013). "Conventional and nanotechniques for DNA methylation profiling". review. The Journal of Molecular Diagnostics. 15 (1): 17–26
MYC (663 words) [view diff] exact match in snippet view article find links to article
hypoxia • G1/S transition of mitotic cell cycle • cytokine-mediated signaling pathway • positive regulation of DNA methylation Sources:Amigo / QuickGO
KAT7 (gene) (1,219 words) [view diff] exact match in snippet view article
acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing". The Journal of Biological Chemistry
Transgelin (942 words) [view diff] exact match in snippet view article find links to article
chromosome 11, and repression of the promoter activity by cytosine DNA methylation". J. Biochem. 122 (1): 157–67. doi:10.1093/oxfordjournals.jbchem.a021722
RHOQ (1,240 words) [view diff] exact match in snippet view article find links to article
kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding". J. Biol. Chem. 279 (33): 34156–64. doi:10.1074/jbc
Homeobox protein NANOG (2,607 words) [view diff] exact match in snippet view article find links to article
D, Jezierski A, Sikorska M, Walker PR (February 2005). "Sequential DNA methylation of the Nanog and Oct-4 upstream regions in human NT2 cells during neuronal
Metastasis suppressor (1,540 words) [view diff] exact match in snippet view article find links to article
priming cells to apoptosis. Cancer cells suppress the gene via promoter DNA methylation hence exemplifies the significance of epigenetic changes in cancer
Body identification (2,653 words) [view diff] exact match in snippet view article find links to article
(2013-09-20). "Body fluid identification by integrated analysis of DNA methylation and body fluid-specific microbial DNA". International Journal of Legal
KDM1A (1,473 words) [view diff] exact match in snippet view article find links to article
lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation". Nature Genetics. 41 (1): 125–9. doi:10.1038/ng.268. PMID 19098913
ID4 (3,026 words) [view diff] exact match in snippet view article find links to article
Hagiwara K, Nagai H, Li Y, Ohashi H, Hotta T, Saito H (2007). "Frequent DNA methylation but not mutation of the ID4 gene in malignant lymphoma". Journal of
Transgelin (942 words) [view diff] exact match in snippet view article find links to article
chromosome 11, and repression of the promoter activity by cytosine DNA methylation". J. Biochem. 122 (1): 157–67. doi:10.1093/oxfordjournals.jbchem.a021722
ID4 (3,026 words) [view diff] exact match in snippet view article find links to article
Hagiwara K, Nagai H, Li Y, Ohashi H, Hotta T, Saito H (2007). "Frequent DNA methylation but not mutation of the ID4 gene in malignant lymphoma". Journal of
Coprinopsis cinerea (1,468 words) [view diff] exact match in snippet view article find links to article
may have important human (or mammalian) implications like cancer. DNA methylation is vital in humans and dysfunction is associated with cancer, thus
Essential hypertension (2,935 words) [view diff] exact match in snippet view article find links to article
genetic loci influencing blood pressure and implicates a role for DNA methylation". Nature Genetics. 47 (11): 1282–1293. doi:10.1038/ng.3405. PMC 4719169
OSR1 (2,690 words) [view diff] exact match in snippet view article find links to article
Rauch TA, Wang Z, Wu X, Kernstine KH, Riggs AD, Pfeifer GP (2012). "DNA methylation biomarkers for lung cancer". Tumour Biology. 33 (2): 287–96. doi:10
Transvection (genetics) (750 words) [view diff] exact match in snippet view article
Magliano M, Cuzin F (Feb 1, 2002). "Transvection effects involving DNA methylation during meiosis in the mouse". EMBO J. 21 (3): 440–50. doi:10.1093/emboj/21
Vacuum activity (1,482 words) [view diff] exact match in snippet view article find links to article
Epigenetics explains how certain mutations (e.g., histone modification and DNA methylation) affect how genes are expressed without altering the genetic code,
T helper 17 cell (3,211 words) [view diff] exact match in snippet view article find links to article
O'Byrne PM, Tebbutt SJ (24 Jun 2014). "Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response". Allergy
CACNA2D3 (974 words) [view diff] exact match in snippet view article find links to article
Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K (2009). "DNA methylation status is inversely correlated with green tea intake and physical activity
RNA-induced transcriptional silencing (963 words) [view diff] exact match in snippet view article find links to article
has been characterized fairly well, and functions primarily through DNA methylation via the RdDM pathway. In this process, which is distinct from the process
Serdar Bulun (808 words) [view diff] exact match in snippet view article find links to article
2013;110:17053-8. Dyson MT, Roqueiro D, Monsivais D, et al. Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in
Mir-185 microRNA precursor family (970 words) [view diff] exact match in snippet view article find links to article
"MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma". Molecular Cancer. 10: 124. doi:10.1186/1476-4598-10-124
Piwi like rna-mediated gene silencing 4 (539 words) [view diff] exact match in snippet view article find links to article
differentiation • GO:0007126 meiotic cell cycle • regulation of translation • DNA methylation involved in gamete generation • spermatogenesis • gene silencing by
MIR141 (692 words) [view diff] exact match in snippet view article find links to article
AE, Dickinson S, Stampfer MR, Futscher BW (January 2010). "Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and
HP1BP3 (1,179 words) [view diff] exact match in snippet view article find links to article
(May 2014). "Antenatal prediction of postpartum depression with blood DNA methylation biomarkers". Molecular Psychiatry. 19 (5): 560–7. doi:10.1038/mp.2013
CLOCK (3,286 words) [view diff] exact match in snippet view article find links to article
April 2011. Joska TM, Zaman R, Belden WJ (September 2014). "Regulated DNA methylation and the circadian clock: implications in cancer". Biology. 3 (3): 560–577
Mir-663 microRNA precursor family (1,392 words) [view diff] exact match in snippet view article find links to article
454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution". BMC Biotechnology. 11: 6. doi:10
Centenarian (5,905 words) [view diff] exact match in snippet view article find links to article
18632/aging.100742. PMC 4468311. PMID 26000617. Horvath, S (2013). "DNA methylation age of human tissues and cell types". Genome Biology. 14 (10): R115
UHRF1 (1,325 words) [view diff] exact match in snippet view article find links to article
process • regulation of transcription, DNA-templated • maintenance of DNA methylation • positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
Vinclozolin (2,364 words) [view diff] exact match in snippet view article find links to article
correlate with epigenetic changes, specifically, an alteration in DNA methylation in the male germ line. However, these transgenerational changes have
Chlamydomonas reinhardtii (2,790 words) [view diff] exact match in snippet view article find links to article
Kenny, C; Berger, L; Pratt, K (September 1978). "Comparative study of DNA methylation in three unicellular eucaryotes". Journal of Bacteriology. 135 (3):
Kang Zhang (2,577 words) [view diff] exact match in snippet view article find links to article
X, Zhang E, Zhang C, Zhu JK, Karin M, Xu RH, Zhang K (July 2017). "DNA methylation markers for diagnosis and prognosis of common cancers". Proc. Natl
Neuronatin (353 words) [view diff] case mismatch in snippet view article find links to article
Daniel R.; Kleinman, Joel E.; Lipska, Barbara K. (10 Feb 2012). "DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex"
Biomarker discovery (1,743 words) [view diff] exact match in snippet view article find links to article
epigenetic clock which measures the age of cells/tissues/organs based on DNA methylation levels is arguably the most accurate genomic biomarker. Using biomarkers
HDAC3 (2,839 words) [view diff] exact match in snippet view article find links to article
Chan DW, Reynolds AB, Qin J, Wong J (September 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Mol
NDUFB6 (1,206 words) [view diff] exact match in snippet view article find links to article
resulting in an adenine to guanine shift at rs629566 was shown to create a DNA methylation site that is associated with a decline in NDUFB6 expression in muscle
PPM1D (1,071 words) [view diff] exact match in snippet view article find links to article
peptidyl-threonine dephosphorylation • negative regulation of cell proliferation • DNA methylation • chromatin silencing • transcription initiation from RNA polymerase
Family with sequence similarity 19 member A4, C-C motif chemokine like (613 words) [view diff] exact match in snippet view article find links to article
Meijer CJ, Heideman DA (2016). "Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical
Senescence (4,541 words) [view diff] exact match in snippet view article find links to article
B180–86. doi:10.1093/gerona/56.4.b180. PMID 11283189. Horvath S (2013). "DNA methylation age of human tissues and cell types". Genome Biology. 14 (10): R115
Valerie Hu (400 words) [view diff] exact match in snippet view article find links to article
that levels of two proteins produced by genes which showed changes in DNA methylation were reduced in the brains of autistic children relative to controls
Ataxia telangiectasia and Rad3 related (1,927 words) [view diff] exact match in snippet view article find links to article
signaling module and regulate two branches of the damage response to DNA methylation". Proceedings of the National Academy of Sciences of the United States
MIR200C (670 words) [view diff] exact match in snippet view article find links to article
AE, Dickinson S, Stampfer MR, Futscher BW (January 2010). "Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and
HERPUD1 (1,030 words) [view diff] exact match in snippet view article find links to article
al. (December 2006). "Homocysteine regulates expression of Herp by DNA methylation involving the AARE and CREB binding sites". Experimental Cell Research
Nuclear receptor co-repressor 1 (2,677 words) [view diff] exact match in snippet view article find links to article
Chan DW, Reynolds AB, Qin J, Wong J (September 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Mol