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searching for ChemMedChem 130 found (137 total)

HYDIA (217 words) [view diff] exact match in snippet view article find links to article

determining interactions of the group II receptor antagonist (3)H-HYDIA". ChemMedChem. 4 (7): 1086–94. doi:10.1002/cmdc.200900028. PMID 19402024. S2CID 9062937

PB-28 (338 words) [view diff] exact match in snippet view article find links to article

computational and experimental probes of interaction with the H2A/H2B dimer". ChemMedChem. 5 (2): 268–73. doi:10.1002/cmdc.200900402. PMID 20077462. S2CID 33532349

LeDock (757 words) [view diff] exact match in snippet view article find links to article

into an Inactive Kinase Conformation Generated by Molecular Dynamics". ChemMedChem. 7 (11): 1983–1990. doi:10.1002/cmdc.201200331. ISSN 1860-7179. Zhao

Combretastatin A-4 (412 words) [view diff] exact match in snippet view article find links to article

Derivatives and their hCE1-Activated Prodrugs as Antiviral Agents". ChemMedChem. 14 (4): 469–483. doi:10.1002/cmdc.201800641. ISSN 1860-7187. PMID 30605241

Arzoxifene (513 words) [view diff] exact match in snippet view article find links to article

selective estrogen receptor modulators including raloxifene and arzoxifene". ChemMedChem. 2 (10): 1520–6. doi:10.1002/cmdc.200700104. PMID 17654759. S2CID 35664796

ADX-47273 (303 words) [view diff] exact match in snippet view article find links to article

pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273". ChemMedChem. 4 (4): 505–11. doi:10.1002/cmdc.200800357. PMC 2865690. PMID 19197923

ACT-335827 (122 words) [view diff] exact match in snippet view article find links to article

available, brain penetrant orexin receptor type 1 selective antagonist". ChemMedChem. 8 (6): 898–903. doi:10.1002/cmdc.201300003. PMID 23589487. S2CID 21644009

Huprine X (554 words) [view diff] exact match in snippet view article find links to article

functionalized at position 9 as highly potent acetylcholinesterase inhibitors". ChemMedChem. 6 (5): 876–88. doi:10.1002/cmdc.201000523. PMID 21344648. S2CID 10893910

Nucleoside (851 words) [view diff] exact match in snippet view article find links to article

Tackling Human Immunodeficiency Virus and Hepatitis Virus Infections". ChemMedChem. 16 (9): 1403–1419. doi:10.1002/cmdc.202000849. PMID 33427377. S2CID 231576801

ABT-202 (155 words) [view diff] exact match in snippet view article find links to article

receptors: structure, function, ligands, and therapeutic potential". ChemMedChem. 2 (6): 746–67. doi:10.1002/cmdc.200600207. PMID 17295372. S2CID 34763474

Amnon Albeck (732 words) [view diff] exact match in snippet view article find links to article

1021/ct3003767; Isr. J. Chem. 2014, 54, 1137-1151, DOI: 10.1002/ijch.201300144. ChemMedChem 2006, 1, 631-638, 639-643, DOI: 10.1002/cmdc.200600029; J. Chem. Info

TC-1698 (224 words) [view diff] exact match in snippet view article find links to article

receptors: structure, function, ligands, and therapeutic potential". ChemMedChem. 2 (6): 746–67. doi:10.1002/cmdc.200600207. PMID 17295372. S2CID 34763474

TC-2216 (133 words) [view diff] exact match in snippet view article find links to article

receptors: structure, function, ligands, and therapeutic potential". ChemMedChem. 2 (6): 746–67. doi:10.1002/cmdc.200600207. PMID 17295372. S2CID 34763474

A-366,833 (212 words) [view diff] exact match in snippet view article find links to article

receptors: structure, function, ligands, and therapeutic potential". ChemMedChem. 2 (6): 746–67. doi:10.1002/cmdc.200600207. PMID 17295372. S2CID 34763474

RD-162 (323 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Halofantrine (597 words) [view diff] exact match in snippet view article find links to article

plasmepsin inhibitors by fragment-based docking and consensus scoring" (PDF). ChemMedChem. 4 (8): 1317–26. doi:10.1002/cmdc.200900078. PMID 19472268. S2CID 14642593

Depsipeptide (987 words) [view diff] exact match in snippet view article find links to article

Optimization of Acyldepsipeptides of the Enopeptin Class Antibiotics". ChemMedChem. 1 (7): 689–693. doi:10.1002/cmdc.200600055. PMID 16902918. S2CID 36525372

Sazetidine A (255 words) [view diff] exact match in snippet view article find links to article

idin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression". ChemMedChem. 4 (8): 1279–91. doi:10.1002/cmdc.200900079. PMC 2955514. PMID 19569163

Galanin receptor (1,378 words) [view diff] exact match in snippet view article find links to article

"Generating orally active galanin analogues with analgesic activities". ChemMedChem. 7 (5): 903–9. doi:10.1002/cmdc.201100574. PMC 4332549. PMID 22374865

BP-897 (608 words) [view diff] exact match in snippet view article find links to article

subtype-selective potential PET radioligands for the dopamine D3 receptor". ChemMedChem. 3 (5): 788–793. doi:10.1002/cmdc.200700327. PMID 18306190. S2CID 23143152

Quisqualamine (298 words) [view diff] exact match in snippet view article find links to article

N-1-alkyl-3-carbonyl-1-hydroxyureas against in vitro cerebral ischemia". ChemMedChem. 5 (1): 79–85. doi:10.1002/cmdc.200900418. PMID 19943277. S2CID 39067721

DIMP (antiandrogen) (554 words) [view diff] exact match in snippet view article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–1661. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Benzothiadiazine (233 words) [view diff] exact match in snippet view article find links to article

Halogenated Benzothiadiazine Derivatives with Anticancer Activity*". ChemMedChem. 16 (7): 1143–1162. doi:10.1002/cmdc.202000729. PMC 8035258. PMID 33331124

Dequalinium (494 words) [view diff] exact match in snippet view article find links to article

their antimicrobial potential: targets or nonspecific interactions?". ChemMedChem. 7 (1): 22–31. doi:10.1002/cmdc.201100404. PMID 22113995. S2CID 26326417

Elbasvir (492 words) [view diff] exact match in snippet view article find links to article

"Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity". ChemMedChem. 8 (12): 1930–40. doi:10.1002/cmdc.201300343. PMID 24127258. S2CID 10543092

RU-59063 (496 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Intrinsic activity (965 words) [view diff] exact match in snippet view article find links to article

-Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation". ChemMedChem. 12 (16): 1335–1348. doi:10.1002/cmdc.201700162. PMC 5573630. PMID 28494140

Ipamorelin (478 words) [view diff] exact match in snippet view article find links to article

(September 2007). "Recent developments in ghrelin receptor ligands". ChemMedChem. 2 (9): 1242–59. doi:10.1002/cmdc.200700015. PMID 17520591. S2CID 24945528

Retinoid X receptor (542 words) [view diff] exact match in snippet view article find links to article

(2016). "An Endogenous Mammalian Retinoid X Receptor Ligand, At Last!". ChemMedChem. 11 (10): 1–12. doi:10.1002/cmdc.201600105. PMID 27151148. S2CID 269196

Hypocretin (orexin) receptor 2 (1,639 words) [view diff] exact match in snippet view article

orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia". ChemMedChem. 9 (2): 311–322. doi:10.1002/cmdc.201300447. PMID 24376006. S2CID 26114114

Michael Albeck (501 words) [view diff] exact match in snippet view article find links to article

1055/s-1989-27344; Inorg. Chem. 1998, 37, 1704, DOI:10.1021/ic971456t; ChemMedChem 2007, 2, 1601, DOI:10.1002/cmdc.200700155. Nature 1987, 330, 173, DOI:10

3-Dehydroquinic acid (294 words) [view diff] exact match in snippet view article find links to article

Inhibition of Type II Dehydroquinase by (2R)-2-Benzyl-3-dehydroquinic Acids". ChemMedChem. 5 (10): 1726–1733. doi:10.1002/cmdc.201000281. PMID 20815012. S2CID 13587154

Spanish Royal Society of Chemistry (847 words) [view diff] exact match in snippet view article find links to article

Inorganic Chemistry, European Journal of Organic Chemistry, ChemBioChem, ChemMedChem and ChemSusChem. The RSEQ is also co-editor of the journal Analytical

Quaternary ammonium cation (2,773 words) [view diff] exact match in snippet view article find links to article

Their Antimicrobial Potential: Targets or Nonspecific Interactions?". ChemMedChem. 7 (1): 22–31. doi:10.1002/cmdc.201100404. PMID 22113995. S2CID 26326417

TM-38837 (166 words) [view diff] exact match in snippet view article find links to article

as a potential peripheral cannabinoid-1 receptor inverse agonist". ChemMedChem. 5 (9): 1439–43. doi:10.1002/cmdc.201000246. PMID 20652930. S2CID 34244587

Finerenone (1,448 words) [view diff] exact match in snippet view article find links to article

mineralocorticoid receptor for the treatment of cardiorenal diseases". ChemMedChem. 7 (8): 1385–1403. doi:10.1002/cmdc.201200081. PMID 22791416. S2CID 36084480

Nitroxoline (1,079 words) [view diff] exact match in snippet view article find links to article

cathepsin B inhibition by antibiotic nitroxoline and related compounds". ChemMedChem. 6 (8): 1351–1356. doi:10.1002/cmdc.201100098. PMID 21598397. S2CID 2963633

Platensimycin (1,252 words) [view diff] exact match in snippet view article find links to article

"Platensimycin, a New Antibiotic and "Superbug Challenger" from Nature". ChemMedChem. 1 (9): 951–4. doi:10.1002/cmdc.200600145. PMID 16952137. Wright, H.

Katherine Seley-Radtke (2,015 words) [view diff] exact match in snippet view article find links to article

Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution. ChemMedChem. 2018;13(2):178–85. Geisman AN, Valuev-Elliston VT, Ozerov AA, et al

Atropisomer (1,902 words) [view diff] exact match in snippet view article find links to article

Oliver (2011). "Revealing Atropisomer Axial Chirality in Drug Discovery". ChemMedChem. 6 (3): 505–513. doi:10.1002/cmdc.201000485. PMID 21360821. S2CID 27354841

Helenalin (1,927 words) [view diff] exact match in snippet view article find links to article

Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles". ChemMedChem. 13 (4): 303–311. doi:10.1002/cmdc.201700752. PMC 5894512. PMID 29349898

Fluorophore (2,024 words) [view diff] exact match in snippet view article find links to article

Injury in C57BL/6 Mice Using a Highly Bright Near-Infrared BODIPY Dye". ChemMedChem. 14 (10): 995–999. doi:10.1002/cmdc.201900181. ISSN 1860-7187. PMID 30920173

List of AM cannabinoids (996 words) [view diff] exact match in snippet view article find links to article

(2009). "The Cannabinoid Receptors. Edited by Patricia H. Reggio". ChemMedChem. 4: 1949. doi:10.1002/cmdc.200900286. Pacher, P.; Bátkai, S; Kunos, G

Serine hydroxymethyltransferase (2,378 words) [view diff] exact match in snippet view article find links to article

antifolate inhibitors of human cytosolic serine hydroxymethyltransferase". ChemMedChem. 10 (3): 490–497. doi:10.1002/cmdc.201500028. PMC 5438088. PMID 25677305

HIV gag stem loop 3 (GSL3) (548 words) [view diff] exact match in snippet view article

HIV-1 by a peptide ligand of the genomic RNA packaging signal Psi". ChemMedChem. 3 (5): 749–755. doi:10.1002/cmdc.200700194. PMID 18205165. Damgaard

Muscarinic acetylcholine receptor M5 (1,508 words) [view diff] exact match in snippet view article find links to article

M5-orthosteric antagonist, VU0488130 (ML381): a novel molecular probe". ChemMedChem. 9 (8): 1677–82. doi:10.1002/cmdc.201402051. PMC 4116439. PMID 24692176

Gerhard Ecker (687 words) [view diff] exact match in snippet view article find links to article

Trapping: Insight from Docking Studies with Propafenone Derivatives". ChemMedChem. 5 (3): 436–442. doi:10.1002/cmdc.200900374. PMID 20146282. S2CID 23597808

GLUT1 (2,591 words) [view diff] exact match in snippet view article find links to article

Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876". ChemMedChem. 7 (11): 3546–55. doi:10.1002/cmdc.201600276. PMC 5095872. PMID 27552707

Acyldepsipeptide antibiotics (2,313 words) [view diff] exact match in snippet view article find links to article

Optimization of Acyldepsipeptides of the Enopeptin Class Antibiotics". ChemMedChem. 1 (7): 689–693. doi:10.1002/cmdc.200600055. PMID 16902918. S2CID 36525372

Adenosine A3 receptor (2,124 words) [view diff] exact match in snippet view article find links to article

pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding". ChemMedChem. 3 (1): 111–119. doi:10.1002/cmdc.200700173. hdl:10261/82277. PMID 18000937

Nucleotide (3,299 words) [view diff] exact match in snippet view article find links to article

Tackling Human Immunodeficiency Virus and Hepatitis Virus Infections". ChemMedChem. 16 (9): 1403–1419. doi:10.1002/cmdc.202000849. PMID 33427377. S2CID 231576801

Uracil (2,942 words) [view diff] exact match in snippet view article find links to article

Tackling Human Immunodeficiency Virus and Hepatitis Virus Infections". ChemMedChem. 16 (9): 1403–1419. doi:10.1002/cmdc.202000849. ISSN 1860-7179. PMID 33427377

Ligand (biochemistry) (3,144 words) [view diff] exact match in snippet view article

(June 2011). "Design strategies for bivalent ligands targeting GPCRs". ChemMedChem. 6 (6): 963–974. doi:10.1002/cmdc.201100101. PMID 21520422. S2CID 10561038

Ferroquine (385 words) [view diff] exact match in snippet view article find links to article

other antimalarials: the development of ferroquine, a new antimalarial". ChemMedChem. 3 (3): 383–391. doi:10.1002/cmdc.200700127. PMC 7162372. PMID 17806092

Pipeline Pilot (864 words) [view diff] exact match in snippet view article find links to article

Filtering and Application of a Bit-Density-Dependent Similarity Function". ChemMedChem. 4 (4): 540–548. doi:10.1002/cmdc.200800408. ISSN 1860-7179. PMID 19263458

Metabotropic glutamate receptor 3 (3,074 words) [view diff] exact match in snippet view article find links to article

6S)-2-amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid-HYDIA". ChemMedChem. 3 (2): 323–35. doi:10.1002/cmdc.200700226. PMID 18058780. S2CID 1695024

Trypanothione-disulfide reductase (632 words) [view diff] exact match in snippet view article find links to article

Trypanothione Reductase: Subversive Substrates and Antitrypanosomal Properties". ChemMedChem. 2 (12): 1708–12. doi:10.1002/cmdc.200700172. PMID 17918760. S2CID 31754415

JNJ-7925476 (1,369 words) [view diff] exact match in snippet view article find links to article

triple monoamine reuptake inhibitors as potential antidepressants". ChemMedChem. 7 (12): 2093–100. doi:10.1002/cmdc.201200352. PMC 3733990. PMID 23060293

Neuroprotection (3,639 words) [view diff] exact match in snippet view article find links to article

approach for neurodegenerative diseases: strategies and mechanisms". ChemMedChem. 7 (3): 359–374. doi:10.1002/cmdc.201100585. PMID 22323134. S2CID 14427130

Albicidin (506 words) [view diff] exact match in snippet view article find links to article

Assessing the Role of N-terminal Acylation on the Antibacterial Activity". ChemMedChem. 11 (17): 1899–1903. doi:10.1002/cmdc.201600231. PMID 27439374. S2CID 5009104

François Diederich (657 words) [view diff] exact match in snippet view article find links to article

Anna K. H. (14 December 2020). "François Diederich – In Memoriam**". ChemMedChem. 16 (1). Wiley: 11–13. doi:10.1002/cmdc.202000920. hdl:10033/622843.

Examorelin (1,306 words) [view diff] exact match in snippet view article find links to article

(September 2007). "Recent developments in ghrelin receptor ligands". ChemMedChem. 2 (9): 1242–1259. doi:10.1002/cmdc.200700015. PMID 17520591. S2CID 24945528

Alpha-7 nicotinic receptor (2,626 words) [view diff] exact match in snippet view article find links to article

potent and selective agonists of α7 nicotinic acetylcholine receptors". ChemMedChem. 6 (5): 889–903. doi:10.1002/cmdc.201000514. PMID 21365765. S2CID 21407917

Quinoxalinedione (346 words) [view diff] exact match in snippet view article find links to article

(2013). "Heterocycles as Nonclassical Bioisosteres of α-Amino Acids". ChemMedChem. 8 (2): 205–215. doi:10.1002/cmdc.201200436. PMID 23322633. S2CID 38623973

Noscapine (2,869 words) [view diff] exact match in snippet view article find links to article

Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure". ChemMedChem. 16 (18): 2882–2894. doi:10.1002/cmdc.202100363. PMID 34159741. S2CID 235610355

Riociguat (2,115 words) [view diff] exact match in snippet view article find links to article

soluble guanylate cyclase for the treatment of pulmonary hypertension". ChemMedChem. 4 (5): 853–65. doi:10.1002/cmdc.200900014. PMC 3313366. PMID 19263460

Caspase 1 (2,392 words) [view diff] exact match in snippet view article find links to article

caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety". ChemMedChem. 5 (5): 730–8. doi:10.1002/cmdc.200900531. PMC 3062473. PMID 20229566

Nonsteroidal antiandrogen (1,576 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

CYP17A1 (2,740 words) [view diff] exact match in snippet view article find links to article

Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer". ChemMedChem. 11 (18): 1983–6. doi:10.1002/cmdc.201600238. PMC 5588864. PMID 27435344

MMP7 (2,277 words) [view diff] exact match in snippet view article find links to article

discovery of MMP7 inhibitors exploiting a novel selectivity trigger". ChemMedChem. 6 (5): 769–73. doi:10.1002/cmdc.201000550. PMID 21520417. S2CID 32715622

Targeted covalent inhibitors (2,061 words) [view diff] exact match in snippet view article find links to article

Non-Michaelis-Menten and Atypical Kinetics in Early Drug Discovery*". ChemMedChem. 16 (6): 899–918. doi:10.1002/cmdc.202000791. PMID 33231926. S2CID 227157473

Eicosanoid receptor (2,893 words) [view diff] exact match in snippet view article find links to article

(2016). "The G Protein-Coupled Receptor GPR17: Overview and Update". ChemMedChem. 11 (23): 2567–2574. doi:10.1002/cmdc.201600453. hdl:11581/394099. PMID 27863043

25CN-NBOH (1,822 words) [view diff] exact match in snippet view article find links to article

for in vitro and in vivo Investigations of the Serotonin 2A Receptor". ChemMedChem. 16 (21): 3263–3270. doi:10.1002/cmdc.202100395. PMID 34288515. S2CID 236157499

Photoactivated peptide (953 words) [view diff] exact match in snippet view article find links to article

Nanoswitchable Inhibitors of Protein–Protein Interactions Involved in Apoptosis". ChemMedChem. 14 (1): 100–106. doi:10.1002/cmdc.201800647. ISSN 1860-7179. PMID 30380184

Jesús Jiménez Barbero (394 words) [view diff] exact match in snippet view article find links to article

Glycoconj. J.(2008-2010) Eur. J. Org. Chem. (2009-2016) ChemBioChem (2011-) ChemMedChem (2013-) Adv Carbohydr Chem Biochem (2013-2016) ACS Chem Biol (2016-)

Apalutamide (3,082 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Charles Louis Alphonse Laveran (3,287 words) [view diff] exact match in snippet view article find links to article

"Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite". ChemMedChem. 16 (10): 1515–1532. doi:10.1002/cmdc.202000895. ISSN 1860-7179. PMC 8252759

BODIPY (1,940 words) [view diff] exact match in snippet view article find links to article

Injury in C57BL/6 Mice Using a Highly Bright Near-Infrared BODIPY Dye". ChemMedChem. 14 (10): 995–999. doi:10.1002/cmdc.201900181. ISSN 1860-7179. PMID 30920173

Doxorubicin (4,385 words) [view diff] exact match in snippet view article find links to article

plasmepsin inhibitors by fragment-based docking and consensus scoring". ChemMedChem. 4 (8): 1317–1326. doi:10.1002/cmdc.200900078. PMID 19472268. S2CID 14642593

Subunit vaccine (6,761 words) [view diff] exact match in snippet view article find links to article

subunit vaccines: development, components, and research opportunities". ChemMedChem. 8 (3): 360–376. doi:10.1002/cmdc.201200487. PMID 23316023. S2CID 205647062

RAPTA (761 words) [view diff] exact match in snippet view article find links to article

protein adducts of anticancer ruthenium(II) arene PTA(RAPTA) complexes". ChemMedChem. 2 (5): 631–635. doi:10.1002/cmdc.200600258. PMID 17366652. S2CID 26537039

Bernd Clement (854 words) [view diff] exact match in snippet view article find links to article

Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment". ChemMedChem. 12 (5): 347–352. doi:10.1002/cmdc.201700026. ISSN 1860-7187. PMID 28099785

Daridorexant (4,075 words) [view diff] exact match in snippet view article find links to article

Receptor Antagonist Daridorexant to 4-Hydroxypiperidinol Metabolites". ChemMedChem. 18 (10): e202300030. doi:10.1002/cmdc.202300030. PMID 36892179. S2CID 257426668

Christian Hartinger (706 words) [view diff] exact match in snippet view article find links to article

metallodrug-protein adducts: ion trap versus time-of-flight mass analyzers. ChemMedChem, 2014, 9 (7), 1351–1355 Hartinger, C. G.; Groessl, M.; Meier, S. M.;

Gunda Georg (813 words) [view diff] exact match in snippet view article find links to article

Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2). ChemMedChem 2017. doi:10.1002/cmdc.201700503. Ayoub, A.; Hawk, M. L.; Herzig, R.

Avasimibe (1,131 words) [view diff] exact match in snippet view article find links to article

2008). "The treatment of dyslipidemia--what's left in the pipeline?". ChemMedChem. 3 (2): 206–21. doi:10.1002/cmdc.200700165. PMID 17963209. S2CID 25244896

Hypoxia-inducible factor (4,913 words) [view diff] exact match in snippet view article find links to article

(April 2016). "Targeting Protein-Protein Interactions in the HIF System". ChemMedChem. 11 (8): 773–86. doi:10.1002/cmdc.201600012. PMC 4848768. PMID 26997519

Enzalutamide (4,551 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

BIM-1 (1,312 words) [view diff] exact match in snippet view article find links to article

Peifer C, Alessi DR (December 2008). "Small-molecule inhibitors of PDK1". ChemMedChem. 3 (12): 1810–38. doi:10.1002/cmdc.200800195. PMID 18972468. S2CID 29838120

Thalidomide (7,473 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–61. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Adenosine A2A receptor (5,102 words) [view diff] exact match in snippet view article find links to article

the development of A(2A) adenosine receptor agonists and antagonists". ChemMedChem. 2 (3): 260–81. doi:10.1002/cmdc.200600193. PMID 17177231. S2CID 6973388

Irosustat (1,564 words) [view diff] exact match in snippet view article find links to article

first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495)". ChemMedChem. 6 (11): 2019–2034. doi:10.1002/cmdc.201100288. PMC 3262147. PMID 21990014

Alpha sheet (1,981 words) [view diff] exact match in snippet view article find links to article

Retro-enantio N-methylated peptides as inhibitors of beta-amyloid aggregation. ChemMedChem 4, 1488-1494. PMID 19591190 Kellock J, Hopping G, Cauchey B, Daggett

Arie Lev Gruzman (1,299 words) [view diff] exact match in snippet view article find links to article

Effective in a Mouse Model of Amyotrophic Lateral Sclerosis (ALS)". ChemMedChem. 10 (5): 850–861. doi:10.1002/cmdc.201500045. ISSN 1860-7179. PMID 25772747

Christopher J. Schofield (4,203 words) [view diff] exact match in snippet view article find links to article

April 2016). "Targeting Protein–Protein Interactions in the HIF System". ChemMedChem. 11 (8): 773–786. doi:10.1002/cmdc.201600012. ISSN 1860-7187. PMC 4848768

Siglec (3,918 words) [view diff] exact match in snippet view article find links to article

2012). "From a library of MAG antagonists to nanomolar CD22 ligands". ChemMedChem. 7 (1): 134–43. doi:10.1002/cmdc.201100407. PMID 21990163. S2CID 28028027

Hypoxia (medicine) (11,638 words) [view diff] exact match in snippet view article

(April 2016). "Targeting Protein-Protein Interactions in the HIF System". ChemMedChem. 11 (8): 773–86. doi:10.1002/cmdc.201600012. PMC 4848768. PMID 26997519

Diazirine (2,309 words) [view diff] exact match in snippet view article find links to article

"Investigation of protein-ligand interactions by mass spectrometry". ChemMedChem. 2 (4): 425–431. doi:10.1002/cmdc.200600298. ISSN 1860-7187. PMID 17299828

Juliane Nguyen (435 words) [view diff] exact match in snippet view article find links to article

Molecular Bioengineering (CMBE) - 2023 International Advisory Board for ChemMedChem - 2021 to present Galenus Guest Professorship - ETH Zuerich - 2024 Elected

YM-254890 (438 words) [view diff] exact match in snippet view article find links to article

Relationship Studies of the Natural Product Gq/11 Protein Inhibitor YM-254890". ChemMedChem. 14 (8): 865–870. doi:10.1002/cmdc.201900018. PMID 30790465. S2CID 73469968

Fluorescence imaging (1,878 words) [view diff] exact match in snippet view article find links to article

Injury in C57BL/6 Mice Using a Highly Bright Near-Infrared BODIPY Dye". ChemMedChem. 14 (10): 995–999. doi:10.1002/cmdc.201900181. ISSN 1860-7179. PMID 30920173

Peter Rutledge (1,220 words) [view diff] exact match in snippet view article find links to article

"Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)". ChemMedChem. 5 (7): 1067–1079. doi:10.1002/cmdc.201000137. PMID 20512795. Spain,

Dynamic combinatorial chemistry (2,944 words) [view diff] exact match in snippet view article find links to article

and dynamic chemistry approach to identify metalloenzyme inhibitors". ChemMedChem. 2 (2): 175–179. doi:10.1002/cmdc.200600250. PMID 17206734. S2CID 36592352

Suvorexant (8,958 words) [view diff] exact match in snippet view article find links to article

2010). "Orexin receptor antagonists: a new concept in CNS disorders?". ChemMedChem. 5 (8): 1197–1214. doi:10.1002/cmdc.201000132. PMID 20544785. S2CID 39427538

Opioid-induced hyperalgesia (3,511 words) [view diff] exact match in snippet view article find links to article

November 2007). "Mu Opioid Receptor Antagonists: Recent Developments". ChemMedChem. 2 (11): 1552–1570. doi:10.1002/cmdc.200700143. PMID 17918759. S2CID 22243459

Alpha-ketoglutarate-dependent hydroxylases (3,976 words) [view diff] exact match in snippet view article find links to article

studies on prolyl hydroxylase domain 2 reveal a new metal binding site". ChemMedChem. 3 (4): 569–572. doi:10.1002/cmdc.200700233. PMID 18058781. S2CID 37628097

Peripherally acting μ-opioid receptor antagonist (3,278 words) [view diff] exact match in snippet view article find links to article

4-dimethyl-4-(3'-hydroxyphenyl)piperidine class of a pure opioid receptor antagonists". ChemMedChem. 9 (8): 1638–1654. doi:10.1002/cmdc.201402142. ISSN 1860-7187. PMC 5588862

Toll-like receptor 4 (9,082 words) [view diff] exact match in snippet view article find links to article

Imidazo[4,5-b]Pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 2". ChemMedChem. 14 (24): 2093–2101. doi:10.1002/cmdc.201900373. PMID 31697454. S2CID 207951964

5-HT2A receptor (9,594 words) [view diff] exact match in snippet view article find links to article

relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors". ChemMedChem. 3 (9): 1299–1309. doi:10.1002/cmdc.200800133. PMID 18666267. S2CID 7537908

Dendrimer (6,905 words) [view diff] exact match in snippet view article find links to article

Dendrimers: Dendrimers Specifically Designed for Pharmaceutical Applications". ChemMedChem. 11 (15): 1583–6. doi:10.1002/cmdc.201600270. PMID 27390296. S2CID 5007374

Alessio Ciulli (1,087 words) [view diff] exact match in snippet view article find links to article

and Elongin BC Substrate Adaptor in Cullin RING E3 Ubiquitin Ligases". ChemMedChem. 12 (18): 1491–1496. doi:10.1002/cmdc.201700359. PMC 5639367. PMID 28776949

Noor Aldeen Atatreh (1,581 words) [view diff] exact match in snippet view article find links to article

Inhibitor Solutions: Understanding the Molecular Basis of Promiscuity. ChemMedChem 2018, 13(6), 500-506. Ghattas, M. A.; Eissa, N. A.; Bardaweel, S. K.;

Peptide therapeutics (2,768 words) [view diff] exact match in snippet view article find links to article

Biopharmaceuticals using Chemical Methods: Alternatives to PEGylation". ChemMedChem. 11 (22): 2474–2495. doi:10.1002/cmdc.201600374. PMID 27775236. S2CID 205649390

Antiandrogen (15,044 words) [view diff] exact match in snippet view article find links to article

"Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10): 1651–1661. doi:10.1002/cmdc.201000259. PMID 20853390. S2CID 23228778

Discovery and development of neuraminidase inhibitors (4,066 words) [view diff] exact match in snippet view article find links to article

Advances in Neuraminidase Inhibitor Development as Anti‐influenza Drugs. ChemMedChem 7.9 (2012): 1527-1536 Chand, Pooran et al. Systematic structure-based

Latrunculin (2,852 words) [view diff] exact match in snippet view article find links to article

preliminary structure-activity relationship and molecular modeling studies". ChemMedChem. 5 (2): 274–85. doi:10.1002/cmdc.200900430. PMC 3529144. PMID 20043312

Valosin-containing protein (5,868 words) [view diff] exact match in snippet view article find links to article

reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase". ChemMedChem. 8 (2): 297–312. doi:10.1002/cmdc.201200520. PMC 3662613. PMID 23316025

Zinc finger inhibitor (1,927 words) [view diff] exact match in snippet view article find links to article

"Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein7". ChemMedChem. 12 (10): 714–721. doi:10.1002/cmdc.201700141. PMC 5572807. PMID 28395128

Molecular glue (2,465 words) [view diff] exact match in snippet view article find links to article

Cell-Surface Receptors, and the Sticky Problem of Finding a Molecular Glue". ChemMedChem. 16 (2): 316–318. doi:10.1002/cmdc.202000683. PMID 33112038. S2CID 225100015

Gold nanoparticles in chemotherapy (5,785 words) [view diff] exact match in snippet view article find links to article

Francois, A. Laroche, N. Pinaud, L. Salmon, J. Ruiz, J. Robert, D. Astruc.; ChemMedChem: Encapsulation of Docetaxel into PEGylated Gold Nanoparticles for Vectorization

Coinage metal N-heterocyclic carbene complexes (2,695 words) [view diff] exact match in snippet view article find links to article

Complexes: Recent Synthetic Strategies and Medicinal Applications". ChemMedChem. 16 (9): 1360–1390. doi:10.1002/cmdc.202000836. ISSN 1860-7179. PMID 33277791

Edward Roberts (chemist) (1,318 words) [view diff] exact match in snippet view article

Binding Cavity is the Main Interaction for Different Y 2 R Antagonists". ChemMedChem. 12 (1): 75–85. doi:10.1002/cmdc.201600433. PMID 27874262. Harris, R

Serotonin–norepinephrine–dopamine reuptake inhibitor (15,216 words) [view diff] exact match in snippet view article find links to article

Oxa-azaspiro derivatives: a novel class of triple re-uptake inhibitors. ChemMedChem. 2010 Mar 1;5(3):361-6. doi: 10.1002/cmdc.200900482. PMID 20112329. Meyerson

Sonodynamic therapy (9,346 words) [view diff] exact match in snippet view article find links to article

Ultrasound and Light on Indocyanine-Green-Treated Tumour Cells and Tissues". ChemMedChem. 7 (8): 1465–1471. doi:10.1002/cmdc.201200233. PMID 22715137. S2CID 28851902

Hedgehog pathway inhibitor (3,864 words) [view diff] exact match in snippet view article find links to article

inhibitors of the hedgehog signaling pathway as cancer therapeutics. ChemMedChem: Chemistry Enabling Drug Discovery. 2010 Apr 6;5(4):500-12. Rimkus T

Donald F. Weaver (1,221 words) [view diff] exact match in snippet view article find links to article

as Indoleamine 2,3‐Dioxygenase 1 (IDO1) Inhibitors". ChemMedChem. 16 (14): 2195–2205. doi:10.1002/cmdc.202100107. ISSN 1860-7179. PMID 33759400

I-motif DNA (7,083 words) [view diff] exact match in snippet view article find links to article

Secondary Structures as Drug Targets: the Prospect of the i-Motif". ChemMedChem. 9 (9): 2026–2030. doi:10.1002/cmdc.201402153. ISSN 1860-7179. PMID 24962454

Fetal protein (1,719 words) [view diff] exact match in snippet view article find links to article

as a Promising Tool for Epigenetic Upregulation of Fetal Hemoglobin". ChemMedChem. 15 (24): 2436–2443. doi:10.1002/cmdc.202000574. PMC 7756256. PMID 33002296

RNA therapeutics (8,886 words) [view diff] exact match in snippet view article find links to article

"Molecular recognition of small-cell lung cancer cells using aptamers". ChemMedChem. 3 (6): 991–1001. doi:10.1002/cmdc.200800030. PMC 3544301. PMID 18338423

Paucimannosylation (6,223 words) [view diff] exact match in snippet view article find links to article

of PA-IIL fromPseudomonas aeruginosa with Disaccharide Derivatives". ChemMedChem. 2 (9): 1328–1338. doi:10.1002/cmdc.200700100. ISSN 1860-7179. PMID 17623286