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searching for Biological target 34 found (306 total)

Quenching (fluorescence) (1,023 words) [view diff] exact match in snippet view article

Quenching and dequenching upon interaction with a specific molecular biological target is the basis for activatable optical contrast agents for molecular

Clinical biophysics (364 words) [view diff] exact match in snippet view article find links to article

the physical signal applied: recognizability: the capacity of the biological target to recognise the presence of the physical energy: this aspect becomes

Alpha-4 beta-2 nicotinic receptor (1,633 words) [view diff] exact match in snippet view article find links to article

affinity at the α4β2 receptor (ki=1 nM), which is also the primary biological target that mediates nicotine's addictive properties. The receptors exist

1966 in spaceflight (370 words) [view diff] no match in snippet view article find links to article

Canaveral LC-19 US Air Force Gemini VIII NASA Low Earth Technology/Biological/Target 17 March 03:22:28 Successful First docking with the Agena target vehicle

Scoring functions for docking (2,545 words) [view diff] exact match in snippet view article find links to article

small organic compound such as a drug and the second is the drug's biological target such as a protein receptor. Scoring functions have also been developed

RAB23 (800 words) [view diff] exact match in snippet view article find links to article

PMID 15489334. Liu YJ, Wang Q, Li W, et al. (2007). "Rab23 is a potential biological target for treating hepatocellular carcinoma". World J. Gastroenterol. 13

Pesticide application (2,666 words) [view diff] exact match in snippet view article find links to article

in the properties of droplets. Historically, dose-transfer to the biological target (i.e. the pest) has been shown to be inefficient. However, relating

Drug development (2,858 words) [view diff] exact match in snippet view article find links to article

drug discovery. These have promising activity against a particular biological target that is important in disease. However, little is known about the safety

Tripterygium wilfordii (1,166 words) [view diff] exact match in snippet view article find links to article

activity, but its clinical use is limited by severe toxicity. The biological target of triptolide is believed to be the XPB subunit of the TFIIH protein

LGALS13 (345 words) [view diff] exact match in snippet view article find links to article

G, Sammar M (February 2013). "Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design

Active site (4,839 words) [view diff] exact match in snippet view article find links to article

of molecular properties on the binding kinetics of a ligand to its biological target". MedChemComm. 3 (4): 449–452. doi:10.1039/c2md00270a. ISSN 2040-2503

Severe cutaneous adverse reactions (4,098 words) [view diff] exact match in snippet view article find links to article

reactions, i.e. reactions in which a drug causes toxicity by impacting a biological target other than the one(s) for which it is intended. They are T cell-initiated

Insilico Medicine (1,679 words) [view diff] case mismatch in snippet view article find links to article

for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform". Frontiers in Aging Neuroscience. 14: 914017.

Denaturation (biochemistry) (3,056 words) [view diff] exact match in snippet view article

still functionally active and tend to fold upon binding to their biological target. In quaternary structure denaturation, protein sub-units are dissociated

JAG2 (1,018 words) [view diff] exact match in snippet view article find links to article

(February 2015). "A MicroRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma". Oncotarget. 6 (5): 2709–24. doi:10

Pesticide drift (2,248 words) [view diff] exact match in snippet view article find links to article

(AI) in droplets falls into the target area, but does not reach the biological target. "Endo-drift" is volumetrically more significant and may therefore

Diphenhydramine (6,172 words) [view diff] exact match in snippet view article find links to article

Overview of diphenhydramine targets and effects Biological target Mode of action Effect H1 receptor Inverse agonist Allergy reduction; Sedation mACh receptors

Nicotine (13,936 words) [view diff] exact match in snippet view article find links to article

binding affinity at the α4β2 receptor (ki=1 nM), which is also the biological target that mediates nicotine's addictive properties. Nicotine has potential

Biometric device (2,245 words) [view diff] exact match in snippet view article find links to article

individual so as to confuse the system between the artifact and the real biological target and gain access to sensitive data/materials. One such high-profile

Troponin C type 1 (4,609 words) [view diff] exact match in snippet view article find links to article

inhibits type 3 phosphodiesterase with nanomolar affinity, so its biological target is controversial. Some compounds have been identified to bind cNTnC

Standardized uptake value (1,529 words) [view diff] case mismatch in snippet view article find links to article

(2008-01-01), Paulino, Arnold C.; Teh, Bin S. (eds.), "chapter 4 - Biological Target Volume", PET-CT in Radiotherapy Treatment Planning, Philadelphia:

MTOR (12,710 words) [view diff] exact match in snippet view article find links to article

the mTOR complexes, mTORC1 (left) and mTORC2 (right). FKBP12, the biological target to which rapamycin binds, is a non-obligate component protein of mTORC1

Neuroinflammation (5,084 words) [view diff] case mismatch in snippet view article find links to article

for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform". Frontiers in Aging Neuroscience. 14: 914017.

Dynamic combinatorial chemistry (2,944 words) [view diff] exact match in snippet view article find links to article

neuraminidase inhibitors generated via selective pressure of the biological target". J. Med. Chem. 46 (3): 356–358. doi:10.1021/jm025589m. PMID 12540234

Cyclothiazomycin (1,128 words) [view diff] exact match in snippet view article find links to article

analogue of cyclothiazomycin is believed to interact with at least one biological target. Cyclothiazomycin A has been shown to inhibit blood plasma renin leading

Regenerative medicine advanced therapy (1,371 words) [view diff] exact match in snippet view article find links to article

List of pharmaceuticals designated as RMATs Name Designee Type Biological target Therapeutic indication ED-101 Abeona Therapeutics cell therapy Collagen

Topological drugs (1,446 words) [view diff] exact match in snippet view article find links to article

biomimetic substituents (“guests”) that bind to the molecules of the biological target (“hosts”) are prospective for the drug design, (iv) the macropolycyclic

Roswell Conspiracies: Aliens, Myths and Legends (6,924 words) [view diff] exact match in snippet view article find links to article

is designed to infiltrate any known fortress, execute a designated biological target and its offspring, and detonate to ensure all traces of it and its

Callystatin A (1,817 words) [view diff] exact match in snippet view article find links to article

believed that this highly conserved structural motif is important for biological target recognition with the α,β-unsaturated lactone moiety serving as the

Boom method (2,534 words) [view diff] exact match in snippet view article find links to article

method for isolating nucleic acid using the same". "Kits for isolating biological target materials using silica magnetic particles". Magnetic Particles Archived

Cinnamycin (1,946 words) [view diff] exact match in snippet view article find links to article

position 15 which mediates the interaction between cinnamycin and its biological target phosphatidylethanolamine and hence important for their antimicrobial

Photonic crystal sensor (1,513 words) [view diff] exact match in snippet view article find links to article

concentrations as low as 15 nM.[citation needed] Certain chemical or biological target molecules can be integrated within the structure to provide specificity

Photoacoustic flow cytometry (2,860 words) [view diff] exact match in snippet view article find links to article

which is dependent on the attenuation through the tissue prior to biological target to be irradiated. Below then establishes the heat-pressure relationship

1965 in spaceflight (October–December) (163 words) [view diff] no match in snippet view article

Canaveral LC-19 US Air Force Gemini VII NASA Low Earth Technology/Biological/Target 18 December 14:05:04 Successful Carried two astronauts, set endurance