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searching for ADAM10 21 found (40 total)

alternate case: aDAM10

Betacellulin (1,755 words) [view diff] exact match in snippet view article find links to article

Dempsey P, Lenhart PM, et al. (December 2007). "The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding

UniGene (1,265 words) [view diff] exact match in snippet view article find links to article

the sequence for human ADAM10 can be retrieved by entering ADAM10, disintegrin, AF009615 (the GenBank accession number of ADAM10), or H69859 (the GenBank

PAK2 (2,164 words) [view diff] exact match in snippet view article find links to article

breast cancer cells, Paxillin phosphorylation at S272 and S274 activates ADAM10 protease, and STAT5 phosphorylation at S779 modulates BCL-ABL-mediated leukemogenesis

CXCL16 (433 words) [view diff] exact match in snippet view article find links to article

TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10". J Immunol. 172 (10): 6362–72. doi:10.4049/jimmunol.172.10.6362. PMID 15128827

FAT1 (2,060 words) [view diff] exact match in snippet view article find links to article

ectodomain of FAT1 can also be shed from the cell surface by the sheddase ADAM10, with release of this ectodomain a possible new biomarker in pancreatic

SPPL2A (715 words) [view diff] exact match in snippet view article find links to article

Guardiola-Serrano F, et al. (2007). "The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells". Cell Death Differ. 14 (9): 1678–87. doi:10

Rudolph E. Tanzi (4,371 words) [view diff] exact match in snippet view article find links to article

pharmaceutical and biotech companies. Other AD genes Tanzi has discovered include ADAM10, UBQLN1, IDE, A2M, ITGB3, and ATXN1. In 2019, Tanzi, his ex-trainee, Jaehong

Protocadherin (1,810 words) [view diff] exact match in snippet view article find links to article

Haas IG, Schulte M, Ludwig A, Frank M, Saftig P (August 2006). "Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell

PCDHGC3 (723 words) [view diff] exact match in snippet view article find links to article

PMID 15489334. Reiss K, Maretzky T, Haas IG, et al. (2006). "Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell

Proximity ligation assay (1,144 words) [view diff] exact match in snippet view article find links to article

PMC 4354543. PMID 25650626. Kwon J, Jeong SM, Choi I, Kim NH (2016). "ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development"

Notch signaling pathway (10,149 words) [view diff] exact match in snippet view article find links to article

extracellular domain interacts with a ligand, an ADAM-family metalloprotease called ADAM10, cleaves the notch protein just outside the membrane. This releases the

Duojia Pan (909 words) [view diff] exact match in snippet view article find links to article

protein kinase (PKA) as a mediator of Hedgehog signaling and Kuzbanian (ADAM10) as a transmembrane metalloprotease responsible for the proteolytic cleavage

Notch proteins (3,548 words) [view diff] exact match in snippet view article find links to article

This protein is called Kuzbanian in Drosophila, sup-17 in C. elegans, and ADAM10 in humans. After proteolytic cleavage, the released NECD is endocytosed

Protectin D1 (2,846 words) [view diff] exact match in snippet view article find links to article

down-regulating β-secretase-1 (BACE1), while up-regulating the α-secretase ADAM10 and the secreted amyloid precursor protein-α (sAPPα). Overall, the above

Estrogen and neurodegenerative diseases (2,223 words) [view diff] exact match in snippet view article find links to article

Anti-amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation". PLOS ONE. 8 (8): e71913. Bibcode:2013PLoSO...871913Z. doi:10

PAK1 (5,251 words) [view diff] exact match in snippet view article find links to article

"HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases". Molecular Cell. 49 (4): 668–79. doi:10.1016/j.molcel.2012.12

CEFIP (1,678 words) [view diff] exact match in snippet view article find links to article

Deficiency, Nuclear Type 1 TSPAN17 Tetraspanin 17 Predicted to regulate ADAM10 maturation Unconfirmed C14orf80 Chromosome 14 Open Reading Frame 80 Unknown

List of EC numbers (EC 3) (15,553 words) [view diff] exact match in snippet view article

pappalysin-1 EC 3.4.24.80: membrane-type matrix metalloproteinase-1 EC 3.4.24.81: ADAM10 endopeptidase EC 3.4.24.82: ADAMTS-4 endopeptidase EC 3.4.24.83: anthrax

Joseph Buxbaum (2,412 words) [view diff] exact match in snippet view article find links to article

Margaret; Buxbaum, Joseph D. (2012-02-01). "Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer disease". Neurobiology of Aging. 33 (2):

Degradomics (5,013 words) [view diff] exact match in snippet view article find links to article

activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresis. Mol. Cell Biol. 26(13):5086-95 (2006)

Dario Angelo Alberto Vignali (3,523 words) [view diff] exact match in snippet view article find links to article

when it could not be shed from the cell surface by the metalloprotease ADAM10, highlighting the ability of LAG3 to serve as a resistance factor limiting